1Division of Endocrinology and Metabolism, Department of Internal Medicine, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
2Division of Endocrinology and Metabolism, Department of Internal Medicine, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Suwon, Korea.
3Division of Endocrinology and Metabolism, Department of Internal Medicine, Soonchunhyang University Bucheon Hospital, Soonchunhyang University College of Medicine, Bucheon, Korea.
4Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
5Division of Endocrinology and Metabolism, Department of Internal Medicine, Inje University Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea.
6Division of Endocrinology and Metabolism, Department of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Korea.
7Gwangmyeong Sungae Hospital, Gwangmyeong, Korea.
8Division of Endocrinology and Metabolism, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
9Department of Endocrinology and Metabolism, Kyung Hee University School of Medicine, Seoul, Korea.
10Department of Internal Medicine, Seoul Metropolitan Government Seoul National University Boramae Medical Center, Seoul National University College of Medicine, Seoul, Korea.
11Department of Internal Medicine, Korea University College of Medicine, Ansan, Korea.
12Division of Endocrinology and Metabolism, Department of Internal Medicine, Chosun University College of Medicine, Gwangju, Korea.
13Sejong St. Mary's Diabetes and Endocrine Clinic, Sejong, Korea.
14Division of Endocrinology and Metabolism, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.
15Department of Internal Medicine, Soonchunhyang University Cheonan Hospital, Soonchunhyang University College of Medicine, Cheonan, Korea.
16Department of Endocrinology and Metabolism, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Korea.
17Department of Endocrinology and Metabolism, Ajou University School of Medicine, Suwon, Korea.
18Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, Korea.
19Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
Copyright © 2019 Korean Diabetes Association
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CONFLICTS OF INTEREST: No potential conflict of interest relevant to this article was reported.
Effect of Switching from Linagliptin to Teneligliptin Dipeptidyl Peptidase-4 Inhibitors in Older Patients with Type 2 Diabetes Mellitus
1. Glycated hemoglobin (HbA1c) level ≥6.5% (HbA1c concentration must be measured through a standardized method)a or |
2. Eight-hour fasting plasma glucose of ≥126 mg/dLa or |
3. Plasma glucose concentration of ≥200 mg/dL at 2 hours after a 75-g oral glucose tolerance testa or |
4. Classic symptoms of diabetes (polyuria, polydipsia, unexplained weight loss) with a random plasma glucose concentration of ≥200 mg/dL |
Cardiovascular diseases | Present | Absent |
---|---|---|
HbA1c, % | <6.5 | |
Blood pressure, mm Hg | <130/80 | <140/85 |
Lipid profiles | ||
LDL-C, mg/dL | <70 | <100a |
Triglycerides, mg/dL | <150 | |
HDL-C, mg/dL | >40 (men) | |
>50 (women) |
aDiagnosis must be confirmed through a repeat test on a different day. However, if more than two criteria are met on the same day, a definite diagnosis can be made.
HbA1c, glycated hemoglobin; LDL-C, low density lipoprotein cholesterol; HDL-C, high density lipoprotein cholesterol. aTarget LDL-C is <70 mg/dL in the presence of target organ damage or cardiovascular risk factors.