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Volume 34(5); October 2010
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Ubiquitous Diabetes Management System via Interactive Communication Based on Information Technologies: Clinical Effects and Perspectives
Jae-Hyoung Cho, Hun-Sung Kim, Jae-Hoon Han, Jin-Hee Lee, Jeong-Ah Oh, Yoon-Hee Choi, Kun-Ho Yoon
Korean Diabetes J. 2010;34(5):267-273.   Published online October 31, 2010
DOI: https://doi.org/10.4093/kdj.2010.34.5.267
  • 3,784 View
  • 28 Download
  • 16 Crossref
AbstractAbstract PDFPubReader   

New diabetes management systems based on interactive communication have been introduced recently, accompanying rapid advances in information technology; these systems are referred to as "ubiquitous diabetes management systems." In such ubiquitous systems, patients and medical teams can communicate via Internet or telecommunications, with patients uploading their glucose data and personal information, and medical teams sending optimal feedback. Clinical evidence from both long-term and short-term trials has been reported by some researchers. Such systems appear to be effective not only in reducing the levels of HbA1c but also in stabilizing glucose control. However, most notably, evidence for the cost-effectiveness of such a system should be demonstrated before it can be propagated out to the general population in actual clinical practice. To establish a cost-effective model, various types of clinical decision supporting software designed to reduce the labor time of physicians must first be developed. A number of sensors and devices for monitoring patients' data are expected to be available in the near future; thus, methods for automatic interconnections between devices and web charts were also developed. Further investigations to demonstrate the clinical outcomes of such a system should be conducted, hopefully leading to a new paradigm of diabetes management.

Citations

Citations to this article as recorded by  
  • Development of a diabetes mobile healthcare system and clinical application in China: a narrative review
    Lin Sun, Zhuo Li, Shugang Xi, Huan Wang, Heyuan Wang, Haimin Wang, Ruoxuan Peng, Qin Xu, Mei Gao, Xianchao Xiao, Gang Wang, Yuan Gao, Guixia Wang, Chenglin Sun
    Journal of Public Health.2021; 29(6): 1471.     CrossRef
  • A case-control study of pattern and determinants of quality of life of patients with diabetes in a developing country
    Ofem Enang, Ogban Omoronyia, Udeme Asibong, Agam Ayuk, Kenneth Nwafor, Annette Legogie
    Journal of the Egyptian Public Health Association.2021;[Epub]     CrossRef
  • Clinical Effects of Remote Glucose Monitoring and Patient-Centered Education Platform for Patients with Diabetes
    Yeoree Yang, Jae-Hyoung Cho
    The Journal of Korean Diabetes.2020; 21(4): 204.     CrossRef
  • Low Cost Inkjet Fabrication of Glucose Electrochemical Sensors Based on Copper Oxide
    R. Bernasconi, A. Mangogna, L. Magagnin
    Journal of The Electrochemical Society.2018; 165(8): B3176.     CrossRef
  • An Internet-based health gateway device for interactive communication and automatic data uploading: Clinical efficacy for type 2 diabetes in a multi-centre trial
    Jae Hyoung Cho, Hun-Sung Kim, Seung Hyun Yoo, Chang Hee Jung, Woo Je Lee, Cheol Young Park, Hae Kyung Yang, Joong Yeol Park, Sung Woo Park, Kun Ho Yoon
    Journal of Telemedicine and Telecare.2017; 23(6): 595.     CrossRef
  • A systematic review on incentive-driven mobile health technology: As used in diabetes management
    Michael de Ridder, Jinman Kim, Yan Jing, Mohamed Khadra, Ralph Nanan
    Journal of Telemedicine and Telecare.2017; 23(1): 26.     CrossRef
  • New Directions in Chronic Disease Management
    Hun-Sung Kim, Jae-Hyoung Cho, Kun-Ho Yoon
    Endocrinology and Metabolism.2015; 30(2): 159.     CrossRef
  • Current Clinical Status of Telehealth in Korea: Categories, Scientific Basis, and Obstacles
    Hun-Sung Kim, Hyunah Kim, Suehyun Lee, Kye Hwa Lee, Ju Han Kim
    Healthcare Informatics Research.2015; 21(4): 244.     CrossRef
  • Using mobile phones in healthcare management for the elderly
    Hun-Sung Kim, Kye-Hwa Lee, Hyunah Kim, Ju Han Kim
    Maturitas.2014; 79(4): 381.     CrossRef
  • Future Prospects of Health Management Systems Using Cellular Phones
    Hun-Sung Kim, Yunji Hwang, Jae-Ho Lee, Hye Young Oh, Yi-Jun Kim, Hyeon Yoon Kwon, Hyoseung Kang, Hyunah Kim, Rae Woong Park, Ju Han Kim
    Telemedicine and e-Health.2014; 20(6): 544.     CrossRef
  • Exploring the Relationship Among User Satisfaction, Compliance, and Clinical Outcomes of Telemedicine Services for Glucose Control
    Mi Jung Rho, Si Ra Kim, Hun-Sung Kim, Jae-Hyoung Cho, Kun-Ho Yoon, Seong K. Mun, In Young Choi
    Telemedicine and e-Health.2014; 20(8): 712.     CrossRef
  • Therapeutic training: past, present and future
    Alexander Sergeevich Ametov, Bulat Iskandarovich Valitov, Natalya Al'bertovna Chernikova
    Diabetes mellitus.2012; 15(1): 71.     CrossRef
  • Continuous glucose monitoring: current clinical use
    Hun‐Sung Kim, Jeong‐Ah Shin, Jin‐Sun Chang, Jae‐Hyoung Cho, Ho‐Young Son, Kun‐Ho Yoon
    Diabetes/Metabolism Research and Reviews.2012; 28(s2): 73.     CrossRef
  • Provider and Systems Factors in Diabetes Quality of Care
    Kimia Ghaznavi, Shaista Malik
    Current Cardiology Reports.2012; 14(1): 97.     CrossRef
  • Effectiveness and safety of a glucose data-filtering system with automatic response software to reduce the physician workload in managing type 2 diabetes
    Jae-Hyoung Cho, Yoon-Hee Choi, Hun-Sung Kim, Jin-Hee Lee, Kun-Ho Yoon
    Journal of Telemedicine and Telecare.2011; 17(5): 257.     CrossRef
  • Effects on diabetes management of a health-care provider mediated, remote coaching system via a PDA-type glucometer and the Internet
    Jae-Hyoung Cho, Hyuk-Sang Kwon, Hun-Sung Kim, Jeong-Ah Oh, Kun-Ho Yoon
    Journal of Telemedicine and Telecare.2011; 17(7): 365.     CrossRef
Role of Pyruvate Dehydrogenase Kinase 4 in Regulation of Blood Glucose Levels
Nam Ho Jeoung, Robert A. Harris
Korean Diabetes J. 2010;34(5):274-283.   Published online October 31, 2010
DOI: https://doi.org/10.4093/kdj.2010.34.5.274
  • 5,658 View
  • 72 Download
  • 48 Crossref
AbstractAbstract PDFPubReader   

In the well-fed state a relatively high activity of the pyruvate dehydrogenase complex (PDC) reduces blood glucose levels by directing the carbon of pyruvate into the citric acid cycle. In the fasted state a relatively low activity of the PDC helps maintain blood glucose levels by conserving pyruvate and other three carbon compounds for gluconeogenesis. The relative activities of the pyruvate dehydrogenase kinases (PDKs) and the opposing pyruvate dehydrogenase phosphatases determine the activity of PDC in the fed and fasted states. Up regulation of PDK4 is largely responsible for inactivation of PDC in the fasted state. PDK4 knockout mice have lower fasting blood glucose levels than wild type mice, proving that up regulation of PDK4 is important for normal glucose homeostasis. In type 2 diabetes, up regulation of PDK4 also inactivates PDC, which promotes gluconeogenesis and thereby contributes to the hyperglycemia characteristic of this disease. When fed a high fat diet, wild type mice develop fasting hyperglycemia but PDK4 knockout mice remain euglycemic, proving that up regulation of PDK4 contributes to hyperglycemia in diabetes. These finding suggest PDK4 inhibitors might prove useful in the treatment of type 2 diabetes.

Citations

Citations to this article as recorded by  
  • Effects of HIIT training and HIIT combined with circuit resistance training on measures of physical fitness, miRNA expression, and metabolic risk factors in overweight/obese middle-aged women
    Zhaleh Pashaei, Abbas Malandish, Shahriar Alipour, Afshar Jafari, Ismail Laher, Anthony C. Hackney, Katsuhiko Suzuki, Urs Granacher, Ayoub Saeidi, Hassane Zouhal
    BMC Sports Science, Medicine and Rehabilitation.2024;[Epub]     CrossRef
  • Hepatic fibrosis: Targeting peroxisome proliferator-activated receptor alpha from mechanism to medicines
    Lijun Gong, Fang Wei, Frank J. Gonzalez, Guolin Li
    Hepatology.2023; 78(5): 1625.     CrossRef
  • microRNA-15b-5p shuttled by mesenchymal stem cell-derived extracellular vesicles protects podocytes from diabetic nephropathy via downregulation of VEGF/PDK4 axis
    Tiantian Zhao, Qingsong Jin, Lili Kong, Dongdong Zhang, Yaqin Teng, Liangyan Lin, Xiaoyan Yao, Yongjun Jin, Minglong Li
    Journal of Bioenergetics and Biomembranes.2022; 54(1): 17.     CrossRef
  • Circulating exosome-derived miR-122-5p is a novel biomarker for prediction of postoperative atrial fibrillation
    Chen Bai, Yisi Liu, Yichen Zhao, Qing Ye, Cheng Zhao, Yang Liu, Jiangang Wang
    Journal of Cardiovascular Translational Research.2022; 15(6): 1393.     CrossRef
  • The impact of different feeds on DNA methylation, glycolysis/gluconeogenesis signaling pathway, and gene expression of sheep muscle
    Feng Song, Zaccheaus Pazamilala Akonyani, Ying Li, Deqiqige Su, Lantuya Wu, Yue Pang, Sile Hu, Dubala Wu, Chun Li, Ding Yang, Jianghong Wu
    PeerJ.2022; 10: e13455.     CrossRef
  • Assessment of hepatic pyruvate carboxylase activity using hyperpolarized [1‐13C]‐l‐lactate
    Jun Chen, Edward P. Hackett, Zoltan Kovacs, Craig R. Malloy, Jae Mo Park
    Magnetic Resonance in Medicine.2021; 85(3): 1175.     CrossRef
  • Loss of metabolic flexibility as a result of overexpression of pyruvate dehydrogenase kinases in muscle, liver and the immune system: Therapeutic targets in metabolic diseases
    Jae‐Han Jeon, Themis Thoudam, Eun Jung Choi, Min‐Ji Kim, Robert A Harris, In‐Kyu Lee
    Journal of Diabetes Investigation.2021; 12(1): 21.     CrossRef
  • Exploring the Genetic Conception of Obesity via the Dual Role of FoxO
    Tapan Behl, Ishnoor Kaur, Aayush Sehgal, Sukhbir Singh, Gokhan Zengin, Nicoleta Negrut, Delia Carmen Nistor-Cseppento, Flavia Maria Pavel, Raluca Anca Corb Aron, Simona Bungau
    International Journal of Molecular Sciences.2021; 22(6): 3179.     CrossRef
  • Pyruvate dehydrogenase kinases (PDKs): an overview toward clinical applications
    Xiuxiu Wang, Xiaoyue Shen, Yuting Yan, Hongmin Li
    Bioscience Reports.2021;[Epub]     CrossRef
  • PDK2: An Underappreciated Regulator of Liver Metabolism
    Benjamin L. Woolbright, Robert A. Harris
    Livers.2021; 1(2): 82.     CrossRef
  • Pyruvate dehydrogenase kinase 1 and 2 deficiency reduces high-fat diet-induced hypertrophic obesity and inhibits the differentiation of preadipocytes into mature adipocytes
    Hyeon-Ji Kang, Byong-Keol Min, Won-Il Choi, Jae-Han Jeon, Dong Wook Kim, Sungmi Park, Yun-Kyung Lee, Hwa-jin Kim, Ju-Eun Byeon, Younghoon Go, Hye Jin Ham, Yong Hyun Jeon, Mi-Jin Kim, Jung Yi Lee, Adam R. Wende, Sung Hee Choi, Robert A. Harris, In-Kyu Lee
    Experimental & Molecular Medicine.2021; 53(9): 1390.     CrossRef
  • Drug evaluation based on phosphomimetic PDHA1 reveals the complexity of activity-related cell death in A549 non-small cell lung cancer cells
    Ling Jin, Minkyoung Cho, Bo-Sung Kim, Jung Ho Han, Sungmi Park, In-Kyu Lee, Dongryeol Ryu, Jae Ho Kim, Sung-Jin Bae, Ki-Tae Ha
    BMB Reports.2021; 54(11): 563.     CrossRef
  • Aberrant PDK4 Promoter Methylation Preceding Hyperglycemia in a Mouse Model
    Sulistyo Emantoko Dwi Putra, Stephanie Singajaya, Ferensia Thesman, Dicky Andhika Pranoto, Ricky Sanjaya, Yoanes Maria Vianney, Ida Bagus Made Artadana
    Applied Biochemistry and Biotechnology.2020; 190(3): 1023.     CrossRef
  • Plasma Lipid Profile and Cardiac Risk Markers in Diabetic Nephropathy
    Nagendra Subba Rammaiah, Praveenkumar Deverbhavi, Kashinath Rattihalli Thirumala
    Journal of Evolution of Medical and Dental Sciences.2020; 9(8): 516.     CrossRef
  • The Role of High-Density Lipoproteins in Endothelial Cell Metabolism and Diabetes-Impaired Angiogenesis
    Khalia R. Primer, Peter J. Psaltis, Joanne T.M. Tan, Christina A. Bursill
    International Journal of Molecular Sciences.2020; 21(10): 3633.     CrossRef
  • The lncRNA ENST00000608794 acts as a competing endogenous RNA to regulate PDK4 expression by sponging miR-15b-5p in dexamethasone induced steatosis
    Fengqiong Liu, Qing Chen, Fa Chen, Jing Wang, Ruijie Gong, Baochang He
    Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids.2019; 1864(10): 1449.     CrossRef
  • The Changing Landscape of Pharmacotherapy for Diabetes Mellitus: A Review of Cardiovascular Outcomes
    Linda Wu, Jenny E. Gunton
    International Journal of Molecular Sciences.2019; 20(23): 5853.     CrossRef
  • Emerging role of the orphan nuclear receptor estrogen-related receptor gamma in liver metabolic diseases
    Don-Kyu Kim, Hueng-Sik Choi
    Liver Research.2019; 3(2): 99.     CrossRef
  • Characterization of in vitro and in vivo metabolism of leelamine using liquid chromatography-tandem mass spectrometry
    Riya Shrestha, Jung Jae Jo, DooHyun Lee, Taeho Lee, Sangkyu Lee
    Xenobiotica.2019; 49(5): 577.     CrossRef
  • Proteomics of Rat Lungs Infected by Cryptococcus gattii Reveals a Potential Warburg-like Effect
    Rafael L. Rosa, Markus Berger, Lucélia Santi, David Driemeier, Paula Barros Terraciano, Alexandre R. Campos, Jorge A. Guimarães, Marilene H. Vainstein, John R. Yates, Walter O. Beys-da-Silva
    Journal of Proteome Research.2019; 18(11): 3885.     CrossRef
  • Dihydrolipoamide dehydrogenase suppression induces human tau phosphorylation by increasing whole body glucose levels in a C. elegans model of Alzheimer’s Disease
    Waqar Ahmad
    Experimental Brain Research.2018; 236(11): 2857.     CrossRef
  • Peroxisome proliferator-activated receptor β/δ does not regulate glucose uptake and lactose synthesis in bovine mammary epithelial cells cultivated in vitro
    Jayant Lohakare, Johan S Osorio, Massimo Bionaz
    Journal of Dairy Research.2018; 85(3): 295.     CrossRef
  • Protective potential of Averrhoa bilimbi fruits in ameliorating the hepatic key enzymes in streptozotocin-induced diabetic rats
    Surya B Kurup, Mini S
    Biomedicine & Pharmacotherapy.2017; 85: 725.     CrossRef
  • Pyruvate dehydrogenase kinase 4 deficiency attenuates cisplatin-induced acute kidney injury
    Chang Joo Oh, Chae-Myeong Ha, Young-Keun Choi, Sungmi Park, Mi Sun Choe, Nam Ho Jeoung, Yang Hoon Huh, Hyo-Jeong Kim, Hee-Seok Kweon, Ji-min Lee, Sun Joo Lee, Jae-Han Jeon, Robert A. Harris, Keun-Gyu Park, In-Kyu Lee
    Kidney International.2017; 91(4): 880.     CrossRef
  • PDK4 Deficiency Induces Intrinsic Apoptosis in Response to Starvation in Fibroblasts from Doberman Pinschers with Dilated Cardiomyopathy
    Kathryn Taggart, Amara Estrada, Patrick Thompson, Francisco Lourenco, Sara Kirmani, Silveli Suzuki-Hatano, Christina A. Pacak
    BioResearch Open Access.2017; 6(1): 182.     CrossRef
  • High-salt intake negatively regulates fat deposition in mouse
    Huanxian Cui, Shuyan Yang, Maiqing Zheng, Ranran Liu, Guiping Zhao, Jie Wen
    Scientific Reports.2017;[Epub]     CrossRef
  • The Effects of Myo-Inositol and B and D Vitamin Supplementation in the db/+ Mouse Model of Gestational Diabetes Mellitus
    Jasmine Plows, Florence Budin, Rebecka Andersson, Valerie Mills, Katherine Mace, Sandra Davidge, Mark Vickers, Philip Baker, Irma Silva-Zolezzi, Joanna Stanley
    Nutrients.2017; 9(2): 141.     CrossRef
  • Transcriptome analysis illuminates the nature of the intracellular interaction in a vertebrate-algal symbiosis
    John A Burns, Huanjia Zhang, Elizabeth Hill, Eunsoo Kim, Ryan Kerney
    eLife.2017;[Epub]     CrossRef
  • Equine performance genes and the future of doping in horseracing
    Tessa Wilkin, Anna Baoutina, Natasha Hamilton
    Drug Testing and Analysis.2017; 9(9): 1456.     CrossRef
  • Urine metabonomic study for blood-replenishing mechanism of Angelica sinensis in a blood-deficient mouse model
    Tao WANG, Hong-Guo SUN, Yong-Li HUA, Peng-Ling LI, Yan-Ming WEI
    Chinese Journal of Natural Medicines.2016; 14(3): 210.     CrossRef
  • MiR-155 Enhances Insulin Sensitivity by Coordinated Regulation of Multiple Genes in Mice
    Xiaolin Lin, Yujuan Qin, Junshuang Jia, Taoyan Lin, Xia Lin, Li Chen, Hui Zeng, Yanjiang Han, Lihong Wu, Shun Huang, Meng Wang, Shenhao Huang, Raoying Xie, Liqi Liang, Yu Liu, Ruiyu Liu, Tingting Zhang, Jing Li, Shengchun Wang, Penghui Sun, Wenhua Huang,
    PLOS Genetics.2016; 12(10): e1006308.     CrossRef
  • Antidiabetic efficacy of citronellol, a citrus monoterpene by ameliorating the hepatic key enzymes of carbohydrate metabolism in streptozotocin-induced diabetic rats
    Subramani Srinivasan, Udaiyar Muruganathan
    Chemico-Biological Interactions.2016; 250: 38.     CrossRef
  • Inflammation increases pyruvate dehydrogenase kinase 4 (PDK4) expression via the Jun N-Terminal Kinase (JNK) pathway in C2C12 cells
    Hana Park, Nam Ho Jeoung
    Biochemical and Biophysical Research Communications.2016; 469(4): 1049.     CrossRef
  • Whole Blood Gene Expression Differentiates between Atrial Fibrillation and Sinus Rhythm after Cardioversion
    Kripa Raman, Stefanie Aeschbacher, Matthias Bossard, Thomas Hochgruber, Andreas J. Zimmermann, Beat A. Kaufmann, Katrin Pumpol, Peter Rickenbacker, Guillaume Paré, David Conen, Alena Talkachova
    PLOS ONE.2016; 11(6): e0157550.     CrossRef
  • Soybean Oil Is More Obesogenic and Diabetogenic than Coconut Oil and Fructose in Mouse: Potential Role for the Liver
    Poonamjot Deol, Jane R. Evans, Joseph Dhahbi, Karthikeyani Chellappa, Diana S. Han, Stephen Spindler, Frances M. Sladek, Jonathan Peterson
    PLOS ONE.2015; 10(7): e0132672.     CrossRef
  • Type 2 diabetes mellitus
    Ralph A. DeFronzo, Ele Ferrannini, Leif Groop, Robert R. Henry, William H. Herman, Jens Juul Holst, Frank B. Hu, C. Ronald Kahn, Itamar Raz, Gerald I. Shulman, Donald C. Simonson, Marcia A. Testa, Ram Weiss
    Nature Reviews Disease Primers.2015;[Epub]     CrossRef
  • Pyruvate Dehydrogenase Kinases: Therapeutic Targets for Diabetes and Cancers
    Nam Ho Jeoung
    Diabetes & Metabolism Journal.2015; 39(3): 188.     CrossRef
  • Differential gene expression pattern in hypothalamus of chickens during fasting-induced metabolic reprogramming: Functions of glucose and lipid metabolism in the feed intake of chickens
    Xin-Ling Fang, Xiao-Tong Zhu, Sheng-Feng Chen, Zhi-Qi Zhang, Qing-Jie Zeng, Lin Deng, Jian-Long Peng, Jian-Jian Yu, Li-Na Wang, Song-Bo Wang, Ping Gao, Qing-Yan Jiang, Gang Shu
    Poultry Science.2014; 93(11): 2841.     CrossRef
  • The pivotal role of pyruvate dehydrogenase kinases in metabolic flexibility
    Shuai Zhang, Matthew W Hulver, Ryan P McMillan, Mark A Cline, Elizabeth R Gilbert
    Nutrition & Metabolism.2014;[Epub]     CrossRef
  • Proteome-Based Systems Biology Analysis of the Diabetic Mouse Aorta Reveals Major Changes in Fatty Acid Biosynthesis as Potential Hallmark in Diabetes Mellitus–Associated Vascular Disease
    Holger Husi, Tom Van Agtmael, William Mullen, Ferdinand H. Bahlmann, Joost P. Schanstra, Antonia Vlahou, Christian Delles, Paul Perco, Harald Mischak
    Circulation: Cardiovascular Genetics.2014; 7(2): 161.     CrossRef
  • Fatty acid elongase-5 (Elovl5) regulates hepatic triglyceride catabolism in obese C57BL/6J mice
    Sasmita Tripathy, Kelli A. Lytle, Robert D. Stevens, James R. Bain, Christopher B. Newgard, Andrew S. Greenberg, Li-Shin Huang, Donald B. Jump
    Journal of Lipid Research.2014; 55(7): 1448.     CrossRef
  • Mechanisms for the adverse effects of late gestational increases in maternal cortisol on the heart revealed by transcriptomic analyses of the fetal septum
    Elaine M. Richards, Charles E. Wood, Maria Belen Rabaglino, Andrew Antolic, Maureen Keller-Wood
    Physiological Genomics.2014; 46(15): 547.     CrossRef
  • Novel Agents for the Treatment of Type 2 Diabetes
    Ralph A. DeFronzo, Curtis L. Triplitt, Muhammad Abdul-Ghani, Eugenio Cersosimo
    Diabetes Spectrum.2014; 27(2): 100.     CrossRef
  • Serotonin (5-HT) Affects Expression of Liver Metabolic Enzymes and Mammary Gland Glucose Transporters during the Transition from Pregnancy to Lactation
    Jimena Laporta, Tonia L. Peters, Kathryn E. Merriman, Chad M. Vezina, Laura L. Hernandez, Julie A. Chowen
    PLoS ONE.2013; 8(2): e57847.     CrossRef
  • Dietary supplementation with vitamin E and C attenuates dexamethasone-induced glucose intolerance in rats
    Deon B. Williams, Zhongxiao Wan, Bruce C. Frier, Rhonda C. Bell, Catherine J. Field, David C. Wright
    American Journal of Physiology-Regulatory, Integrative and Comparative Physiology.2012; 302(1): R49.     CrossRef
  • Association of pyruvate dehydrogenase kinase 4 gene polymorphisms with type 2 diabetes and metabolic syndrome
    Seong-Su Moon, Jung-Eun Lee, Young-Sil Lee, Su-Won Kim, Nam Ho Jeoung, In-Kyu Lee, Jung-Guk Kim
    Diabetes Research and Clinical Practice.2012; 95(2): 230.     CrossRef
  • Sex-dependent differences in rat hepatic lipid accumulation and insulin sensitivity in response to diet-induced obesity
    Antònia Nadal-Casellas, Ana Maria Proenza, Isabel Lladó, Magdalena Gianotti
    Biochemistry and Cell Biology.2012; 90(2): 164.     CrossRef
  • Prednisolone-Induced Changes in Gene-Expression Profiles in Healthy Volunteers
    Erik JM Toonen, Wilco WM Fleuren, Ulla Nässander, Marie-José C van Lierop, Susanne Bauerschmidt, Wim HA Dokter, Wynand Alkema
    Pharmacogenomics.2011; 12(7): 985.     CrossRef
Editorial
The Association of Brachial-Ankle Pulse Wave Velocity with Acute Postprandial Hyperglycemia in Korean Prediabetic and Diabetic Subjects
Chul Woo Ahn
Korean Diabetes J. 2010;34(5):284-286.   Published online October 31, 2010
DOI: https://doi.org/10.4093/kdj.2010.34.5.284
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PDFPubReader   

Citations

Citations to this article as recorded by  
  • Regular Intermittent Aerobic Exercise Reduces Arterial Stiffness Associated with Postprandial Hyperglycemia in Middle-Aged and Older Individuals
    Ryota Kobayashi, Hideyuki Negoro
    BioMed.2024; 4(1): 39.     CrossRef
Original Articles
The Association of Brachial-Ankle Pulse Wave Velocity with 30-Minute Post-Challenge Plasma Glucose Levels in Korean Adults with No History of Type 2 Diabetes
Eun-Suk Choi, Eun-Jung Rhee, Ji-Hoon Choi, Ji-Cheol Bae, Seung-Hyun Yoo, Won-Jun Kim, Se-Eun Park, Cheol-Young Park, Won-Young Lee, Yong-Kyun Cho, Ki-Won Oh, Sung-Woo Park, Sun-Woo Kim
Korean Diabetes J. 2010;34(5):287-293.   Published online October 31, 2010
DOI: https://doi.org/10.4093/kdj.2010.34.5.287
  • 4,367 View
  • 33 Download
  • 10 Crossref
AbstractAbstract PDFPubReader   
Background

Acute postprandial hyperglycemia is an important affector for atherosclerosis in subjects with glucose intolerance. We analyzed the relationship of brachial-ankle pulse wave velocity (baPWV) with fasting and post-challenge plasma glucose levels according to different time points during oral glucose tolerance test (OGTT).

Methods

In 663 subjects with fasting hyperglycemia, 75 g OGTT were performed to confirm the glucose tolerant status, and fasting, post-challenge 30-minute and 120-minute glucose levels were measured. Anthropometric measurements were done, and fasting lipid profiles were measured. baPWV were measured in all subjects and the relationship between fasting, 30- and 120-minute post-challenge glucose levels and baPWV were analyzed.

Results

Among the participants, 62.9% were prediabetes and 31.7% were diabetes. Mean baPWV value was significantly higher in subjects with diabetes compared with prediabetes group. In bivariate correlation analyses, age, blood pressure, total cholesterol, low density lipoprotein cholesterol, 30-minute and 120-minute post-challenge glucose levels showed significant positive correlation with baPWV value. In multiple regression analysis, 30-minute post-challenge glucose level was a weak but significant determinant for mean baPWV value even after adjustment for other confounding variables.

Conclusions

Postprandial hyperglycemia, especially 30-minute glucose levels showed significant correlation with baPWV in subjects with fasting hyperglycemia. These results can imply the deleterious effect of acute hyperglycemic excursion on arterial stiffness in subjects with glucose intolerance.

Citations

Citations to this article as recorded by  
  • One-Hour Post-Load Plasma Glucose Levels are Associated with Early Arterial Stiffness in Subjects with Different Glucose Tolerance
    Rui Wang, Xiao-li Liu, Xiao-jiao Jia, Yan Liu, Qiang Lu
    Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy.2022; Volume 15: 1537.     CrossRef
  • The Temporal Pattern of Arterial Stiffness during Aging: A Large-Scale Cross-Sectional Study
    Zhengli Tang, Yuanyuan Lu, Yiming Hao, Robert Morris, Di Kang, Fang Wang, Lin Fan, Weijian Wang, Yiqin Wang, Feng Cheng, Gaetano Santulli
    Journal of Diabetes Research.2021; 2021: 1.     CrossRef
  • Newly diagnosed abnormal glucose tolerance determines post-MI prognosis in patients with hospital related hyperglycaemia but without known diabetes
    Sudipta Chattopadhyay, Anish George, Joseph John, Thozhukat Sathyapalan
    Journal of Diabetes and its Complications.2020; 34(4): 107518.     CrossRef
  • The effect of oral glucose tolerance testing on changes in arterial stiffness and blood pressure in elderly women with hypertension and relationships between the stage of diabetes and physical fitness levels
    Jaesong Lee, Wonil Park, Eunsook Sung, Bokbeom Kim, Nahyun Kim, Saejong Park, Chulho Shin, Jonghoon Park
    Physical Activity and Nutrition.2020; 24(4): 34.     CrossRef
  • Two-hour post-challenge glucose is a better predictor of adverse outcome after myocardial infarction than fasting or admission glucose in patients without diabetes
    Sudipta Chattopadhyay, Anish George, Joseph John, Thozhukat Sathyapalan
    Acta Diabetologica.2018; 55(5): 449.     CrossRef
  • Adjustment of the GRACE score by 2-hour post-load glucose improves prediction of long-term major adverse cardiac events in acute coronary syndrome in patients without known diabetes
    Sudipta Chattopadhyay, Anish George, Joseph John, Thozhukat Sathyapalan
    European Heart Journal.2018; 39(29): 2740.     CrossRef
  • Investigating the Effect of Glucose on Aortic Pulse Wave Velocity Using Pancreatic Clamping Methodology
    Houry Puzantian, Karen Teff, Raymond R. Townsend
    Biological Research For Nursing.2015; 17(3): 270.     CrossRef
  • Association between the Postprandial Glucose Levels and Arterial Stiffness Measured According to the Cardio-ankle Vascular Index in Non-diabetic Subjects
    Atsuko Tsuboi, Chikako Ito, Rumi Fujikawa, Hideya Yamamoto, Yasuki Kihara
    Internal Medicine.2015; 54(16): 1961.     CrossRef
  • Insulin Sensitivity and Beta-Cell Function Are Associated with Arterial Stiffness in Individuals without Hypertension
    Chuchen Meng, Min Sun, Zhixiao Wang, Qi Fu, Mengdie Cao, Zhenxin Zhu, Jia Mao, Yun Shi, Wei Tang, Xiaoping Huang, Yu Duan, Tao Yang
    Journal of Diabetes Research.2013; 2013: 1.     CrossRef
  • Urinary adiponectin concentration is positively associated with micro- and macro-vascular complications
    Won Seon Jeon, Ji Woo Park, Namseok Lee, Se Eun Park, Eun Jung Rhee, Won Young Lee, Ki Won Oh, Sung Woo Park, Cheol-Young Park, Byung-Soo Youn
    Cardiovascular Diabetology.2013;[Epub]     CrossRef
Bone Mineral Density in Prediabetic Men
Ju Hee Lee, Yun Hyeong Lee, Kyoung Hye Jung, Min Kyeong Kim, Hye Won Jang, Tae Kyun Kim, Hyun Jin Kim, Young Suk Jo, Minho Shong, Tae Yong Lee, Bon Jeong Ku
Korean Diabetes J. 2010;34(5):294-302.   Published online October 31, 2010
DOI: https://doi.org/10.4093/kdj.2010.34.5.294
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AbstractAbstract PDFPubReader   
Background

There are many studies regarding the effects of insulin on bone metabolism and changes in bone mineral density (BMD) in the setting of diabetes. The effect of prediabetes on BMD is not known.

Methods

A total of 802 men participated in the Korea Rural Genomic Cohort Study (in Geumsan County). According to the results of an oral glucose tolerance test, subjects were classified into normal, prediabetic, and diabetic categories. One hundred twenty-four subjects diagnosed with type 2 diabetes were excluded, leaving 678 subjects for the study inclusion. BMD was estimated with a quantitative ultrasonometer.

Results

The average BMD T scores of normal and prediabetic subjects were -1.34 ± 1.42 and -1.33 ± 1.30, respectively; there was no significant difference in the BMD T scores between these groups. The BMD T score was inversely associated with age and positively correlated with body weight, body mass index, total cholesterol, low density lipoprotein cholesterol, and HbA1c. On multiple linear regression analysis, low density lipoprotein cholesterol was the only statistically significant variable for prediabetes (β = 0.007, P = 0.005). On the stepwise regression analysis, age (β = -0.026, P < 0.001), the body mass index (β = 0.079, P < 0.001), and low density lipoprotein cholesterol (β = 0.004, P = 0.016) were significant variables for prediabetes.

Conclusions

There was no significant difference in the BMD T score between the normal and prediabetic subjects. Further studies are needed regarding the association of fracture risk and changes in BMD with the development of overt diabetes.

Citations

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  • More Rapid Bone Mineral Density Loss in Older Men With Diabetes: The Osteoporotic Fractures in Men (MrOS) Study
    Flavia Tramontana, Nicola Napoli, Stephanie Litwack-Harrison, Douglas C Bauer, Eric S Orwoll, Jane A Cauley, Elsa S Strotmeyer, Ann V Schwartz
    The Journal of Clinical Endocrinology & Metabolism.2024;[Epub]     CrossRef
  • Prediabetes and skeletal health
    Catherine Lindsay, Albert Shieh
    Current Opinion in Endocrinology, Diabetes & Obesity.2023; 30(4): 200.     CrossRef
  • Serum levels of sclerostin in prediabetes and its correlation with bone mineral density
    Ajay Chauhan, Manoj Kumar Bhakhar, Parul Goyal
    Journal of Family Medicine and Primary Care.2023; 12(11): 2702.     CrossRef
  • The risk of hip fractures in individuals over 50 years old with prediabetes and type 2 diabetes – A longitudinal nationwide population-based study
    Ho Youn Park, Kyoungdo Han, Youngwoo Kim, Yoon Hwan Kim, Yoo Joon Sur
    Bone.2021; 142: 115691.     CrossRef
  • Bone health in diabetes and prediabetes
    Silvia Costantini, Caterina Conte
    World Journal of Diabetes.2019; 10(8): 421.     CrossRef
  • Bone mineral density in obese children with prediabetes
    Ala ÜSTYOL, Mehmet Emre ATABEK
    Ege Tıp Dergisi.2018; 57(2): 94.     CrossRef
  • The Prevalence of Osteopenia and Osteoporosis Among Malaysian Type 2 Diabetic Patients Using Quantitative Ultrasound Densitometer
    Shaymaa Abdalwahed Abdulameer, Mohanad Naji Sahib, Syed Azhar Syed Sulaiman
    The Open Rheumatology Journal.2018; 12(1): 50.     CrossRef
  • An association between bone mineral density and anabolic hormones in middle-aged and elderly men with prediabetes
    Michał Rabijewski, Lucyna Papierska, Paweł Piątkiewicz
    The Aging Male.2017; : 1.     CrossRef
  • Amplification of transcutaneous and percutaneous bone-conduction devices with a test-band in an induced model of conductive hearing loss
    Marn Joon Park, Jae Ryung Lee, Chan Joo Yang, Myung Hoon Yoo, In Suk Jin, Chi Ho Choi, Hong Ju Park
    International Journal of Audiology.2016; 55(11): 653.     CrossRef
  • Osteoporosis in Men with Diabetes Mellitus
    Claire Issa, Mira S. Zantout, Sami T. Azar
    Journal of Osteoporosis.2011; 2011: 1.     CrossRef
  • Response: Bone Mineral Density in Prediabetic Men (Korean Diabetes J 2010;34:294-302)
    Ju Hee Lee, Hyun Jin Kim, Bon Jeong Ku
    Korean Diabetes Journal.2010; 34(6): 386.     CrossRef
  • Letter: Bone Mineral Density in Prediabetic Men (Korean Diabetes J 2010;34:294-302)
    Chul-Hee Kim
    Korean Diabetes Journal.2010; 34(6): 384.     CrossRef
A Comparative Study of Diet in Good and Poor Glycemic Control Groups in Elderly Patients with Type 2 Diabetes Mellitus
Mi-Hye Woo, Soojin Park, Jeong-Taek Woo, Ryowon Choue
Korean Diabetes J. 2010;34(5):303-311.   Published online October 31, 2010
DOI: https://doi.org/10.4093/kdj.2010.34.5.303
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AbstractAbstract PDFPubReader   
Background

Identification of dietary patterns is important for glycemic management in elderly patients with type 2 diabetes mellitus (T2DM).

Methods

Elderly T2DM patients (> 65 years of age, n = 48) were categorized based on their concentration of glycated hemoglobin (HbA1c). Subjects with HbA1c levels below 7% were placed in the good control (GC) group and those with HbA1c levels equal to or above 8% were placed in the poor control (PC) group. Anthropometric data, blood parameters, and dietary intake records were compared between the groups. Statistical analysis included Student's t-test, chi-square test, and Pearson correlation coefficient test.

Results

Anthropometric data, including body mass index (24.7 ± 2.9 kg/m2), did not differ between the GC and PC groups. Significant abnormalities in blood glucose levels (P < 0.01), lean body mass (P < 0.01), and plasma protein and albumin levels (P < 0.05, P < 0.01) were found in the PC group. In contrast to the GC group, the PC group depended on carbohydrate (P = 0.014) rather than protein (P = 0.013) or fat (P = 0.005) as a major source of energy, and had a lower index of nutritional quality for nutrients such as protein (P = 0.001), and all vitamins and minerals (P < 0.001, 0.01, or 0.05 for individual nutrients), except vitamin C, in their usual diet. Negative correlations between HbA1c levels and protein (r = -0.338, P < 0.05) or fat (r = -0.385, P < 0.01) intakes were also found.

Conclusions

Healthcare professionals should encourage elderly diabetic patients to consume a balanced diet to maintain good glycemic control.

Citations

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  • Effects of Vitamin Intake on Blood Glucose in Cancer Patients Undergoing Chemotherapy: Quantitative and Descriptive Research
    Ji Yeong Kim, Kyung Hee Lim
    Korean Journal of Adult Nursing.2023; 35(2): 148.     CrossRef
  • Malnutrition in elderly patients with type 2 diabetes mellitus in a Nigerian tertiary hospital: A cross-sectional study
    Oladimeji Adedeji Junaid, Olubukola Ayoola Ojo, Oluseyi Ademola Adejumo, Folorunsho Mansally Junaid, Kehinde John Ajiboye, Olalekan Ezekiel Ojo, Toluwani Olusola Akitikori, Ayodeji Babatope Kolawole, Temidayo Rosemary Ikem
    Dialogues in Health.2022; 1: 100030.     CrossRef
  • Increased stress, weight gain and less exercise in relation to glycemic control in people with type 1 and type 2 diabetes during the COVID-19 pandemic
    Merel M Ruissen, Hannah Regeer, Cyril P Landstra, Marielle Schroijen, Ingrid Jazet, Michiel F Nijhoff, Hanno Pijl, Bart E P B Ballieux, Olaf Dekkers, Sasja D Huisman, Eelco J P de Koning
    BMJ Open Diabetes Research & Care.2021; 9(1): e002035.     CrossRef
  • Medical nutrition therapy and dietary counseling for patients with diabetes-energy, carbohydrates, protein intake and dietary counseling
    Toshimasa Yamauchi, Hideki Kamiya, Kazunori Utsunomiya, Hirotaka Watada, Daiji Kawanami, Junko Sato, Munehiro Kitada, Daisuke Koya, Norio Harada, Kenichiro Shide, Erina Joo, Ryo Suzuki, Ryotaro Bouchi, Yasuharu Ohta, Tatsuya Kondo
    Diabetology International.2020; 11(3): 224.     CrossRef
  • Dietary survey in Japanese patients with type 2 diabetes and the influence of dietary carbohydrate on glycated hemoglobin: The Sleep and Food Registry in Kanagawa study
    Tadashi Yamakawa, Rika Sakamoto, Kenichiro Takahashi, Jun Suzuki, Minori Matuura‐Shinoda, Mayumi Takahashi, Erina Shigematsu, Shunichi Tanaka, Mizuki Kaneshiro, Taro Asakura, Takehiro Kawata, Yoshihiko Yamada, Uru Nezu Osada, Tetsuo Isozaki, Atsushi Takah
    Journal of Diabetes Investigation.2019; 10(2): 309.     CrossRef
  • Association between dietary habit and diabetic risk profiles among diagnosed Type-2 diabetic patients in a selected area of Bangladesh
    Md. Abdul Majid, Md. Abdul Bashet, Md. Ruhul Furkan Siddique, Md. Estiar Rahman
    Diabetes & Metabolic Syndrome: Clinical Research & Reviews.2019; 13(2): 1633.     CrossRef
  • Impact of High-Carbohydrate Diet on Metabolic Parameters in Patients with Type 2 Diabetes
    Chan-Hee Jung, Kyung Mook Choi
    Nutrients.2017; 9(4): 322.     CrossRef
  • Total Energy Intake May Be More Associated with Glycemic Control Compared to Each Proportion of Macronutrients in the Korean Diabetic Population
    Hye Mi Kang, Dong-Jun Kim
    Diabetes & Metabolism Journal.2012; 36(4): 300.     CrossRef
  • Diet Therapy for Postprandial Hyperglycemia in Patients with Diabetes
    Jeong-a Yoo
    Journal of Korean Diabetes.2012; 13(1): 33.     CrossRef
  • Optimal energy distribution of carbohydrate intake for Japanese elderly patients with type 2 diabetes: The Japanese Elderly Intervention Trial
    Chiemi Kamada, Hidenori Yoshimura, Ryota Okumura, Keiko Takahashi, Satoshi Iimuro, Yasuo Ohashi, Atsushi Araki, Hiroyuki Umegaki, Takashi Sakurai, Yukio Yoshimura, Hideki Ito
    Geriatrics & Gerontology International.2012; 12(s1): 41.     CrossRef
The Effect of Tribbles-Related Protein 3 on ER Stress-Suppressed Insulin Gene Expression in INS-1 Cells
Young Yun Jang, Nam Keong Kim, Mi Kyung Kim, Ho Young Lee, Sang Jin Kim, Hye Soon Kim, Hye-Young Seo, In Kyu Lee, Keun Gyu Park
Korean Diabetes J. 2010;34(5):312-319.   Published online October 31, 2010
DOI: https://doi.org/10.4093/kdj.2010.34.5.312
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AbstractAbstract PDFPubReader   
Background

The highly developed endoplasmic reticulum (ER) structure in pancreatic beta cells is heavily involved in insulin biosynthesis. Thus, any perturbation in ER function inevitably impacts insulin biosynthesis. Recent studies showed that the expression of tribbles-related protein 3 (TRB3), a mammalian homolog of Drosophilia tribbles, in various cell types is induced by ER stress. Here, we examined whether ER stress induces TRB3 expression in INS-1 cells and found that TRB3 mediates ER stress-induced suppression of insulin gene expression.

Methods

The effects of tunicamycin and thapsigargin on insulin and TRB3 expression in INS-1 cells were measured by Northern and Western blot analysis, respectively. The effects of adenovirus-mediated overexpression of TRB3 on insulin, PDX-1 and MafA gene expression in INS-1 cells were measured by Northern blot analysis. The effect of TRB3 on insulin promoter was measured by transient transfection study with constructs of human insulin promoter.

Results

The treatment of INS-1 cells with tunicamycin and thapsigargin decreased insulin mRNA expression, but increased TRB3 protein expression. Adenovirus-mediated overexpression of TRB3 decreased insulin gene expression in a dose-dependent manner. A transient transfection study showed that TRB3 inhibited insulin promoter activity, suggesting that TRB3 inhibited insulin gene expression at transcriptional level. Adenovirus-mediated overexpression of TRB3 also decreased PDX-1 mRNA expression, but did not influence MafA mRNA expression.

Conclusions

This study showed that ER stress induced TRB3 expression, but decreased both insulin and PDX-1 gene expression in INS-1 cells. Our data suggest that TRB3 plays an important role in ER stress-induced beta cell dysfunction.

Citations

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  • Endoplasmic reticulum stress causes insulin resistance by inhibiting delivery of newly synthesized insulin receptors to the cell surface
    Max Brown, Samantha Dainty, Natalie Strudwick, Adina D. Mihai, Jamie N. Watson, Robina Dendooven, Adrienne W. Paton, James C. Paton, Martin Schröder, James Arthur Olzmann
    Molecular Biology of the Cell.2020; 31(23): 2597.     CrossRef
  • PTB and TIAR binding to insulin mRNA 3′- and 5′UTRs; implications for insulin biosynthesis and messenger stability
    Rikard G. Fred, Syrina Mehrabi, Christopher M. Adams, Nils Welsh
    Heliyon.2016; 2(9): e00159.     CrossRef
  • Asna1/TRC40 Controls β-Cell Function and Endoplasmic Reticulum Homeostasis by Ensuring Retrograde Transport
    Stefan Norlin, Vishal S. Parekh, Peter Naredi, Helena Edlund
    Diabetes.2016; 65(1): 110.     CrossRef
  • Role of the Unfolded Protein Response inβCell Compensation and Failure during Diabetes
    Nabil Rabhi, Elisabet Salas, Philippe Froguel, Jean-Sébastien Annicotte
    Journal of Diabetes Research.2014; 2014: 1.     CrossRef
  • Endoplasmic Reticulum Stress and Insulin Biosynthesis: A Review
    Mi-Kyung Kim, Hye-Soon Kim, In-Kyu Lee, Keun-Gyu Park
    Experimental Diabetes Research.2012; 2012: 1.     CrossRef
ENPP1 K121Q Genotype Not Associated with Coronary Artery Calcification in Korean Patients with Type 2 Diabetes Mellitus
Dae Joon Jeong, Dong Gyu Lee, Hee-Jung Kim, Eun Hee Cho, Sang-Wook Kim
Korean Diabetes J. 2010;34(5):320-326.   Published online October 31, 2010
DOI: https://doi.org/10.4093/kdj.2010.34.5.320
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AbstractAbstract PDFPubReader   
Background

Ectonucleotide pyrophosphatase/phosphodiesterase-1 (ENPP1) generates inorganic pyrophosphate, a solute that serves as an essential physiological inhibitor of calcification. Inactivating mutations of ENPP1 are associated with generalized calcification in infancy and an increased risk of developing type 2 diabetes mellitus (T2DM). We hypothesized that the ENPP1 K121Q variant may be associated with increased coronary artery calcification in T2DM patients.

Methods

The study subjects were aged 34 to 85 years and showed no evidence of clinical cardiovascular disease prior to recruitment. A total of 140 patients with T2DM were assessed for their coronary artery calcium (CAC) scores and ENPP1 K121Q polymorphisms were identified.

Results

The prevalence of subjects carrying the KQ genotype was 12.9% (n = 18). There were no 121QQ homozygotes. Patients with the KQ genotype did not show a significantly higher CAC score (122 vs. 18; P = 0.858). We matched each patient with the KQ genotype to a respective control with the KK genotype by gender, age, and duration of diabetes. When compared to matched controls, we observed no significant difference in CAC score (P = 0.959).

Conclusions

The ENPP1 K121Q polymorphism does not appear to be associated with coronary artery calcification in patients with T2DM.

Citations

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  • Evaluation of NPP1 as a Novel Biomarker of Coronary Artery Disease: A Pilot Study in Human Beings
    Amir Hooshang Mohammadpour, Saeed Nazemi, Fatemeh Mashhadi, Atefeh Rezapour, Mohammad Afshar, Sepideh Afzalnia, Afsaneh Mohammadi, Hamid Reza Mashreghi Moghadam, Maryam Moradian, Seyed Mohammad Hasan Moallem, Saeed Falahaty, Azadeh Zayerzadeh, Sepideh Ely
    Advanced Pharmaceutical Bulletin.2018; 8(3): 489.     CrossRef
  • ENPP1 121Q functional variant enhances susceptibility to coronary artery disease in South Indian patients with type 2 diabetes mellitus
    S. Sumi, Surya Ramachandran, V RamanKutty, Maulin M. Patel, T. N. Anand, Ajit S Mullasari, C. C. Kartha
    Molecular and Cellular Biochemistry.2017; 435(1-2): 67.     CrossRef
  • Genetics in Arterial Calcification
    Frank Rutsch, Yvonne Nitschke, Robert Terkeltaub, Dwight A. Towler
    Circulation Research.2011; 109(5): 578.     CrossRef
  • Distribution of allelic variants of genes inhibitors and activators ectopic calcification in patients with acute coronary syndrome
    V. Yu. Harbuzova, O. A. Obukhova, I. O. Rozumenko, Ye. I. Dubovyk, T. M. Oleshko, Ye. A. Harbuzova, D. V. Shvachko, O. V. Ataman
    Faktori eksperimental'noi evolucii organizmiv.1970; 21: 306.     CrossRef
Letter
Response
Response: The Relationship between Lung Function and Metabolic Syndrome in Obese and Non-Obese Korean Adult Males (Korean Diabetes J 2010;34:253-60)
Soo Kyoung Kim, Jae Hyeon Kim
Korean Diabetes J. 2010;34(5):329-330.   Published online October 31, 2010
DOI: https://doi.org/10.4093/kdj.2010.34.5.329
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