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Enhancing Diabetes Care through a Mobile Application: A Randomized Clinical Trial on Integrating Physical and Mental Health among Disadvantaged Individuals
Jae Hyun Bae, Eun Hee Park, Hae Kyung Lee, Kun Ho Yoon, Kyu Chang Won, Hyun Mi Kim, Sin Gon Kim
Diabetes Metab J. 2024;48(4):790-801.   Published online February 2, 2024
DOI: https://doi.org/10.4093/dmj.2023.0298
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AbstractAbstract PDFSupplementary MaterialPubReader   ePub   
Background
This study examines integrating physical and mental healthcare for disadvantaged persons with type 2 diabetes mellitus and mild-to-moderate depression in the community, using a mobile application within a public-private-academic partnership.
Methods
The Korean Diabetes Association has developed a mobile application combining behavioral activation for psychological well-being and diabetes self-management, with conventional medical therapy. Participants were randomly assigned to receive the application with usual care or only usual care. Primary outcomes measured changes in psychological status and diabetes selfmanagement through questionnaires at week 12 from the baseline. Secondary outcomes assessed glycemic and lipid control, with psychological assessments at week 16.
Results
Thirty-nine of 73 participants completed the study (20 and 19 in the intervention and control groups, respectively) and were included in the analysis. At week 12, the intervention group showed significant reductions in depression severity and perceived stress compared to the control group. Additionally, they reported increased perceived social support and demonstrated improved diabetes self-care behavior. These positive effects persisted through week 16, with the added benefit of reduced anxiety. While fasting glucose levels in the intervention group tended to improve, no other significant differences were observed in laboratory assessments between the groups.
Conclusion
This study provides compelling evidence for the potential efficacy of a mobile application that integrates physical and mental health components to address depressive symptoms and enhance diabetes self-management in disadvantaged individuals with type 2 diabetes mellitus and depression. Further research involving larger and more diverse populations is warranted to validate these findings and solidify their implications.

Citations

Citations to this article as recorded by  
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    Journal of Affective Disorders.2026; 393: 120297.     CrossRef
  • Social determinants of health and type 2 diabetes in Asia
    Kyunghun Sung, Seung‐Hwan Lee
    Journal of Diabetes Investigation.2025; 16(6): 971.     CrossRef
  • 2025 Clinical Practice Guidelines for Diabetes Management in Korea: Recommendation of the Korean Diabetes Association
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    Review of Managerial Science.2025;[Epub]     CrossRef
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    Applied Psychology: Health and Well-Being.2025;[Epub]     CrossRef
  • Tele–Cognitive Behavioral Therapy for the Treatment of Diabetes-Related Distress in Individuals With Diabetes Mellitus: Systematic Review and Meta-Analysis of Randomized Controlled Trials
    Xiaohong Xu, Fang Wang, Shunqi Liao, Jingxian Liu, Lingyi Xiao
    Journal of Medical Internet Research.2025; 27: e80476.     CrossRef

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