Diabetes Metab J > Volume 30(4); 2006 > Article
Korean Diabetes Journal 2006;30(4):312-315.
DOI: https://doi.org/10.4093/jkda.2006.30.4.312    Published online July 1, 2006.
A Case of Acromegaly Presenting with Diabetic Ketoacidosis.
Jin Dong Kim, Tae Seo Sohn, Jee In Lee, Jick Hwan Hah, Yun Hwa Jung, Jung Min Lee, Sung Min Nam, Seung Won Lee, Hyun Shik Son
Division of Endocrinology and Metabolism, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Korea.
In patients with acromegaly, glucose intolerance and diabetes mellitus are one of the frequent manifestations. And the type of diabetes in these patients is usually non-insulin dependent type secondary to insulin resistance caused by growth hormone excess. Therefore, the diabetes mellitus in these patients dose not tend to develop diabetic ketoacidosis. But we experienced and presented the case of a patient with acromegaly hospitalized due to the diabetic ketoacidosis without overt clinical manifestations of acromegaly. This case of acromegaly showed that growth hormone excess could cause diabetic ketoacidosis in the presence of relative insulin deficiency.
Key Words: Acromegaly, Diabetic ketoacidosis, Insulin resistance, Growth hormone

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