Skip Navigation
Skip to contents

Diabetes Metab J : Diabetes & Metabolism Journal

Search
OPEN ACCESS

Articles

Page Path
HOME > Diabetes Metab J > Volume 31(3); 2007 > Article
Review Mitochondrial Gene Therapy.
Kyung Soo Ko
Diabetes & Metabolism Journal 2007;31(3):187-192
DOI: https://doi.org/10.4093/jkda.2007.31.3.187
Published online: May 1, 2007
  • 1,504 Views
  • 24 Download
  • 0 Crossref
  • 0 Scopus
Mitochondrial Research Group, Department of Internal Medicine, College of Medicine, Inje University, Korea.

Mitochondrial dysfunction contributes to a large variety of human disorders, ranging from neurodegenerative and neuromuscular diseases, obesity, and diabetes to ischemia-reperfusion injury and cancer. Increasing pharmacological efforts toward therapeutic interventions have been made leading to the emergence of 'Mitochondrial Medicine' as a new field of biomedical research. The identification of molecular mitochondrial drugs targets in combination with the development of methods for selectively delivering biologically active molecules to the site of mitochondria will eventually launch a multitude of new therapies for the treatment of mitochondria-related diseases, which are based either on the selective protection, repair, or eradication of cells. Yet, while tremendous efforts are being undertaken to identify new mitochondrial drugs and drug targets, the development of mitochondria-specific drug carrier systems is lagging behind. To ensure a high efficiency of current and future mitochondrial therapeutics, delivery systems need to be developed, which are able to selectively transport biologically active molecules to and into mitochondria within living cells.

  • Cite
    CITE
    export Copy
    Close
    Download Citation
    Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.

    Format:
    • RIS — For EndNote, ProCite, RefWorks, and most other reference management software
    • BibTeX — For JabRef, BibDesk, and other BibTeX-specific software
    Include:
    • Citation for the content below
    Mitochondrial Gene Therapy.
    Korean Diabetes J. 2007;31(3):187-192.   Published online May 1, 2007
    Close
Related articles

Diabetes Metab J : Diabetes & Metabolism Journal