1Division of Endocrinology and Metabolism, Department of Medicine, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea.
2Division of Endocrinology and Metabolism, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
3Department of Biostatistic, The Catholic University of Korea, Seoul, Korea.
4Department of Statistics and Actuarial Science, Soongsil University, Seoul, Korea.
5Division of Endocrinology and Metabolism, Department of Medicine, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Medicine, Seoul, Korea.
6Department of Clinical Research Design and Evaluation, Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University, Seoul, Korea.
Copyright © 2018 Korean Diabetes Association
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2007 | 2008 | 2009 | 2010 | 2011 | 2012 | 2013 | P for trend | |
---|---|---|---|---|---|---|---|---|
Total population | ||||||||
Total number | 49,570,064 | 49,884,461 | 50,175,381 | 50,455,745 | 50,771,065 | 51,020,532 | 51,289,103 | |
Male | 24,864,222 (50.16) | 25,016,666 (50.15) | 25,154,436 (50.13) | 25,287,443 (50.12) | 25,438,317 (50.10) | 25,542,446 (50.06) | 25,669,471 (50.05) | |
Female | 24,705,842 (49.84) | 24,867,795 (49.85) | 25,020,945 (49.87) | 25,168,302 (49.88) | 25,332,748 (49.90) | 25,478,086 (49.94) | 25,619,632 (49.95) | |
Age, yr | 36.08±20.39 | 36.53±20.26 | 37.07±20.54 | 37.56±20.69 | 38.02±20.74 | 38.46±20.84 | 38.94±20.96 | |
Prevalent cases | ||||||||
Total number | 21,131 | 21,935 | 21,497 | 20,814 | 21,551 | 23,129 | 23,932 | |
Male | 11,363 (53.77) | 11,820 (53.89) | 11,683 (54.35) | 11,178 (53.70) | 11,587 (53.77) | 12,427 (53.73) | 12,954 (54.13) | |
Female | 9,768 (46.23) | 10,115 (46.11) | 9,814 (45.65) | 9,636 (46.30) | 9,964 (46.23) | 10,702 (46.27) | 10,978 (45.87) | |
Age, yr | 54.08±18.44 | 54.00±18.07 | 53.89±18.67 | 52.93±19.32 | 52.54±19.49 | 51.96±19.74 | 51.36±20.1 | |
Prevalence (per 100,000) | ||||||||
Total | 42.63 | 43.97 | 42.84 | 41.25 | 42.45 | 45.33 | 46.66 | <0.0001 |
Prevalence (per 100,000) by sex | ||||||||
Male | 45.70 | 47.25 | 46.45 | 44.20 | 45.55 | 48.65 | 50.46 | <0.0001 |
Female | 39.54 | 40.68 | 39.22 | 38.29 | 39.33 | 42.00 | 42.85 | <0.0001 |
2007 | 2008 | 2009 | 2010 | 2011 | 2012 | 2013 | P for trend | |
---|---|---|---|---|---|---|---|---|
Incident cases | ||||||||
Total number | 2,489 | 2,284 | 2,124 | 1,767 | 2,102 | 1,802 | 1,400 | |
Male | 1,375 (55.24) | 1,254 (54.90) | 1,195 (56.26) | 1,003 (56.76) | 1,202 (57.18) | 995 (55.22) | 820 (58.57) | |
Female | 1,114 (44.76) | 1,030 (45.10) | 929 (43.74) | 764 (43.24) | 900 (42.82) | 807 (44.78) | 580 (41.43) | |
Age, yr | 54.24±20.60 | 54.13±17.37 | 53.97±17.73 | 52.55±18.50 | 52.49±19.31 | 52.27±21.00 | 49.62±21.74 | |
Incidence rate (per 100,000) | ||||||||
Total | 5.02 | 4.58 | 4.23 | 3.5 | 4.14 | 3.53 | 2.73 | <0.0001 |
Incidence rate (per 100,000) by sex | ||||||||
Male | 5.53 | 5.01 | 4.75 | 3.97 | 4.73 | 3.90 | 3.19 | <0.0001 |
Female | 4.51 | 4.14 | 3.71 | 3.04 | 3.55 | 3.17 | 2.26 | <0.0001 |
Incidence rate (per 100,000) by age | ||||||||
0–19 yr | 1.47 | 1.28 | 1.33 | 1.42 | 1.82 | 1.82 | 1.76 | <0.0001 |
20 yr or older | 6.17 | 5.62 | 5.12 | 4.12 | 4.81 | 4.01 | 2.99 | <0.0001 |
Incident T1DM cases | Prevalent T1DM cases | |||||
---|---|---|---|---|---|---|
Typical T1DM | Atypical T1DM | Total T1DM | Typical T1DM | Atypical T1DM | Total T1DM | |
Total number | 565 | 835 | 1,400 | 16,190 | 7,742 | 23,932 |
Male | 320 (56.64) | 500 (59.88) | 820 (58.57) | 8,779 (54.22) | 4,175 (53.93) | 12,954 (54.13) |
Female | 245 (43.36) | 335 (40.12) | 580 (41.43) | 7,411 (45.78) | 3,567 (46.07) | 10,978 (45.87) |
Age, yr | 35.72±22.55 | 58.83±13.58 | 49.62±21.74 | 49.48±20.78 | 55.24±17.55 | 51.36±20.10 |
Rate (per 100,000) | ||||||
Male | 1.25 | 1.95 | 3.19 | 34.20 | 16.26 | 50.46 |
Female | 0.96 | 1.31 | 2.26 | 28.93 | 13.92 | 42.85 |
Total | 1.10 | 1.63 | 2.73 | 31.57 | 15.09 | 46.66 |
Year | 2007 | 2008 | 2009 | 2010 | 2011 | 2012 | 2013 |
---|---|---|---|---|---|---|---|
Total population in national preventive health care database | |||||||
Number | 7,878,249 | 9,751,365 | 10,490,491 | 11,447,468 | 11,687,229 | 12,144,200 | 11,739,899 |
Men | 4,563,167 (57.92) | 5,525,658 (56.67) | 5,785,632 (55.15) | 6,293,856 (54.98) | 6,408,686 (54.83) | 6,615,411 (54.47) | 6,385,819 (54.39) |
Age, yr | 45.89±14.34 | 45.67±14.01 | 47.11±14.13 | 47.46±13.90 | 47.66±14.00 | 48.21±13.90 | 48.38±14.16 |
Clinical characteristics of patients with prevalent T1DM | |||||||
Number | 2,998 | 3,843 | 4,235 | 4,220 | 4,480 | 5,198 | 4,910 |
Men | 1,813 (60.47) | 2,323 (60.45) | 2,482 (58.61) | 2,486 (58.91) | 2,646 (59.06) | 3,081 (59.27) | 2,921 (59.49) |
Women | 1,185 (39.53) | 1,520 (39.55) | 1,753 (41.39) | 1,734 (41.09) | 1,834 (40.94) | 2,117 (40.73) | 1,989 (40.51) |
Age, yr | 57.30±13.31 | 56.56±13.37 | 58.35±12.72 | 57.56±13.17 | 57.44±13.64 | 56.80±13.93 | 55.89±14.35 |
Current smoker | 683 (22.78) | 854 (22.22) | 941 (22.22) | 959 (22.73) | 1,017 (22.7) | 1,209 (23.26) | 1,114 (22.69) |
Body weight, kg | 63.59±10.29 | 63.9±10.57 | 64.02±10.48 | 64.11±10.94 | 64.52±11.01 | 64.23±11.28 | 64.44±11.64 |
BMI, kg/m2 | 24.12±3.23 | 24.10±3.24 | 24.29±3.3 | 24.23±3.34 | 24.27±3.34 | 24.10±3.38 | 24.05±3.44 |
Waist circumference, cm | NA | NA | 84.49±8.94 | 84.11±9.23 | 84.13±9.39 | 83.61±9.57 | 83.34±9.75 |
Systolic BP, mm Hg | 129.07±17.14 | 128.20±16.97 | 127.71±16.52 | 127.37±16.42 | 127.26±16.31 | 126.55±16.49 | 125.86±15.84 |
Diastolic BP, mm Hg | 77.80±10.22 | 77.32±10.01 | 77.03±10.00 | 76.76±10.05 | 76.45±10.01 | 75.98±9.97 | 75.62±9.72 |
Fasting glucose, mg/dL | 158.50±72.60 | 152.74±69.07 | 155.03±68.33 | 151.45±66.51 | 151.41±66.55 | 150.10±66.15 | 150.63±67.58 |
Total cholesterol, mg/dL | 191.73±42.29 | 188.46±40.75 | 189.10±41.12 | 185.55±39.64 | 183.26±40.36 | 179.97±39.08 | 179.69±39.70 |
Triglyceride, mg/dL | NA | NA | 121.0 (82.0–181.0) | 114.0 (79.0–169.0) | 112.0 (77.0–170.0) | 110.0 (75.0–168.0) | 108.0 (72.0–162.0) |
HDL-C, mg/dL | NA | NA | 52.79±22.57 | 51.96±16.65 | 52.18±14.71 | 52.30±16.08 | 52.77±15.65 |
LDL-C, mg/dL | NA | NA | 107.02±41.90 | 106.39±37.68 | 103.98±39.56 | 101.03±35.10 | 100.88±34.79 |
LDL-C ≥100 mg/dL | NA | NA | 2,348 (55.44) | 2,321 (55.00) | 2,351 (52.48) | 2,526 (48.6) | 2,382 (48.51) |
Proteinuria (urine dipstick positivity) | 445 (14.84) | 506 (13.17) | 716 (16.91) | 641 (15.19) | 717 (16.00) | 781 (15.03) | 690 (14.05) |
In patients with prevalent T1DM | In patients with age and sex-matcheda prevalent T2DM | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
2009 | 2010 | 2011 | 2012 | 2013 | 2009 | 2010 | 2011 | 2012 | 2013 | |
Prevalence of metabolic syndrome | ||||||||||
Total, unadjusted | 2,890 (68.24) | 2,836 (67.20) | 3,020 (67.41) | 3,498 (67.30) | 3,313 (67.47) | 6,400 (75.56) | 6,439 (76.29) | 6,809 (75.99) | 7,990 (76.86) | 7,621 (77.61) |
Men | 1,486 (59.87) | 1,474 (59.29) | 1,618 (61.15) | 1,881 (61.05) | 1,824 (62.44) | 3,486 (70.23) | 3,537 (71.14) | 3,740 (70.67) | 4,466 (72.48) | 4,278 (73.25) |
Women | 1,404 (80.09) | 1,362 (78.55) | 1,402 (76.44) | 1,617 (76.38) | 1,489 (74.86) | 2,914 (83.11) | 2,902 (83.68) | 3,069 (83.67) | 3,524 (83.23) | 3,343 (83.99) |
Total, age and sex-adjusted, %b | 53.99 | 51.65 | 51.97 | 53.50 | 55.06 | 69.71 | 70.47 | 70.73 | 73.01 | 74.17 |
Prevalence of individual components of metabolic syndrome | ||||||||||
Abdominal obesityc | 1,908 (45.05) | 1,848 (43.79) | 1,939 (43.28) | 2,126 (40.90) | 1,948 (39.67) | 4,096 (48.87) | 4,103 (49.30) | 4,285 (48.34) | 4,884 (47.67) | 4,689 (48.47) |
Men | 775 (31.22) | 766 (30.81) | 832 (31.44) | 926 (30.06) | 886 (30.33) | 1,782 (36.26) | 1,850 (37.83) | 1,869 (35.79) | 2,213 (36.56) | 2,163 (37.72) |
Women | 1,133 (64.63) | 1,082 (62.40) | 1,107 (60.36) | 1,200 (56.68) | 1,062 (53.39) | 2,314 (66.72) | 2,253 (65.63) | 2,416 (66.34) | 2,671 (63.70) | 2,526 (64.13) |
BP ≥130/85 mm Hg or medication use | 3,071 (72.51) | 2,993 (70.92) | 3,189 (71.18) | 3,568 (68.64) | 3,349 (68.21) | 6,136 (73.20) | 6,136 (73.72) | 6,420 (72.43) | 7,464 (72.85) | 6,920 (71.53) |
Men | 1,779 (71.68) | 1,735 (69.79) | 1,878 (70.98) | 2,095 (68.00) | 2,032 (69.57) | 3,632 (73.91) | 3,636 (74.36) | 3,823 (73.21) | 4,484 (74.08) | 4,217 (73.53) |
Women | 1,292 (73.70) | 1,258 (72.55) | 1,311 (71.48) | 1,473 (69.58) | 1,317 (66.21) | 2,504 (72.20) | 2,500 (72.82) | 2,597 (71.31) | 2,980 (71.07) | 2,703 (68.62) |
Triglyceride ≥150 mg/dL or medicationd use | 2,357 (55.66) | 2,287 (54.19) | 2,456 (54.82) | 2,919 (56.16) | 2,776 (56.54) | 5,418 (64.64) | 5,455 (65.54) | 5,917 (66.75) | 6,930 (67.64) | 6,610 (68.33) |
Men | 1,270 (51.17) | 1,259 (50.64) | 1,364 (51.55) | 1,630 (52.90) | 1,562 (53.47) | 3,124 (63.57) | 3,170 (64.83) | 3,460 (66.26) | 4,083 (67.45) | 3,907 (68.13) |
Women | 1,087 (62.01) | 1,028 (59.28) | 1,092 (59.54) | 1,289 (60.89) | 1,214 (61.04) | 2,294 (66.15) | 2,285 (66.56) | 2,457 (67.46) | 2,847 (67.90) | 2,703 (68.62) |
HDL-C | 2,273 (53.67) | 2,286 (54.17) | 2,454 (54.78) | 2,949 (56.73) | 2,849 (58.02) | 4,767 (56.87) | 4,873 (58.55) | 5,272 (59.48) | 6,337 (61.85) | 6,153 (63.60) |
Men <40 mg/dL or medicationd use | 1,098 (44.24) | 1,126 (45.29) | 1,245 (47.05) | 1,518 (49.27) | 1,500 (51.35) | 2,379 (48.41) | 2,485 (50.82) | 2,684 (51.40) | 3,308 (54.65) | 3,277 (57.14) |
Women <50 mg/dL or medicationd use | 1,175 (67.03) | 1,160 (66.90) | 1,209 (65.92) | 1,431 (67.60) | 1,349 (67.82) | 2,388 (68.86) | 2,388 (69.56) | 2,588 (71.06) | 3,029 (72.24) | 2,876 (73.01) |
Values are presented as number (%) or mean±standard deviation.
Values are presented as number (%) or mean±standard deviation.
Values are presented as number (%) or mean±standard deviation. T1DM, type 1 diabetes mellitus.
Values are presented as number (%), mean±standard deviation, or median (interquartile range). T1DM, type 1 diabetes mellitus; BMI, body mass index; BP, blood pressure; NA, not available; HDL-C, high density lipoprotein cholesterol; LDL-C, low density
Values are presented as number (%). T1DM, type 1 diabetes mellitus; T2DM, type 2 diabetes mellitus; BP, blood pressure; HDL-C, high density lipoprotein cholesterol. aPatients with T1DM and those with T2DM were matched 1:2 according to age and sex for adjustment, bDirect age and sex-adjustment was performed for the Korean population in the year 2010, cWaist circumference >90 cm in men and >80 cm in women using Asian-specific cut-off for abdominal obesity, dStatins, fibrates, and ezetimibes were included.