1Department of Biochemistry, Yonsei University Wonju College of Medicine, Wonju, Korea.
2Mitohormesis Research Center, Yonsei University Wonju College of Medicine, Wonju, Korea.
3Institute of Lifestyle Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.
4Department of Physiology, Yonsei University Wonju College of Medicine, Wonju, Korea.
5Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.
6Institute of Genomic Cohort, Yonsei University Wonju College of Medicine, Wonju, Korea.
7Department of Preventive Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.
Copyright © 2019 Korean Diabetes Association
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Values are presented as mean±standard deviation or number (%). Paired t-tests were carried out for comparison.
ANGPTL6, angiopoietin-like 6; BMI, body mass index; BP, blood pressure; TG, triglyceride; HDL-C, high density lipoprotein cholesterol; LDL-C, low density lipoprotein cholesterol; HOMA-IR, homeostasis model assessment of insulin resistance; HbA1c, glycosylated hemoglobin; AST, aspartate transaminase; ALT, alanine transaminase; GGT, gamma-glutamyl transferase; CRP, C-reactive protein.
Changes of components no. | No. | Serum ANGPTL6, ng/mL | P value for trend |
---|---|---|---|
Decreased | 56 | 46.52±16.59 | |
Not changed | 65 | 49.92±21.00 | 0.003 |
Increased | 100 | 62.01±40.33 |
Values are presented as odd ratio (95% confidence interval). Model 1: baseline ANGPTL6, sex, age, and baseline number of MetS components; Model 2: Model 1+additionally adjusted with baseline body mass index, low density lipoprotein, smoking, and regular exercise; Model 3: Model 2+additionally adjusted with baseline homeostasis model assessment of insulin resistance and C-reactive protein.
ANGPTL6, angiopoietin-like 6; MetS, metabolic syndrome; HDL-C, high density lipoprotein cholesterol; TG, triglyceride; WC, waist circumference; BP, blood pressure.
aSubjects with each component of MetS at baseline have been excluded.