1Department of Anatomy, Jahrom University of Medical Sciences, Jahrom, Iran.
2Research Center for Non-Communicable Diseases, Jahrom University of Medical Sciences, Jahrom, Iran.
3Department of New Sciences and Technology, Mashhad University of Medical Sciences, Mashhad, Iran.
Copyright © 2015 Korean Diabetes Association
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Variable | NGT subjects | Type 2 diabetic subjects | P value |
---|---|---|---|
Sex, male/female | 71/129 (35.5/64.5) | 63/137 (31.5/68.5) | 0.397 |
Age, yr | 11.1±51.6 | 13.5±52.7 | 0.199 |
BMI, kg/m2 | 11.3±27 | 16.2±28.4 | 0.031 |
FBG, mg/dL | 9.3±93.5 | 70±159.6 | <0.001 |
Total cholesterol, mg/dL | 44.4±197.6 | 56.6±206.1 | 0.205 |
HDL-C, mg/dL | 8.9±42.8 | 25.5±45.8 | 0.299 |
LDL-C, mg/dL | 33.1±125.1 | 42.8±122.6 | 0.545 |
TG, mg/dL | 77.9±150.9 | 122.7±186.2 | 0.001 |
Genotype | NGT subjects (n=200) | Type 2 diabetic subjects (n=200) | Odds ratio | P value |
---|---|---|---|---|
rs12255372 (G/T) | ||||
GG | 148 (75) | 130 (65) | Reference | Reference |
TG | 46 (22) | 59 (29.5) | 0.646 (0.410-1.019) | 0.060 |
TT | 6 (3) | 11 (6.5) | 0.473 (0.170-1.314) | 0.151 |
TT+TG | 52 (24) | 70 (35) | 0.619 (0.402-0.954) | 0.038 |
GG | 148 (76) | 130 (65) | ||
Frequency of T allele, % | 14.5 | 20.3 | 0.668 (0.461-0.967) | 0.033 |
rs7903146 (C/T) | ||||
CC | 126 (63) | 109 (54.5) | Reference | |
TC | 59 (29.5) | 68 (34) | 0.751 (0.487-1.157) | 0.194 |
TT | 15 (7.5) | 23 (11.5) | 0.564 (0.280-1.135) | 0.109 |
TT+TC | 74 (37) | 91 (45.5) | 0.703 (0.472-1.049) | 0.104 |
CC | 126 (63) | 109 (54.5) | ||
Frequency of T allele, % | 22.25 | 28.5 | 0.718 (0.521-0.989) | 0.043 |
Variable | rs12255372 (G/T) | rs7903146 (C/T) | ||||
---|---|---|---|---|---|---|
TT+TG | GG | P value | TT+TC | CC | P value | |
BMI, kg/m2 | 28.5±1.9 | 27.3±0.59 | 0.478 | 27.7±0.9 | 27.7±0.9 | 0.991 |
Fasting glucose, mg/dL | 129.4±5.5 | 125.3±3.6 | 0.536 | 120.6±3.9 | 131.1±4.2 | 0.086 |
Total cholesterol, mg/dL | 212.2±4.7 | 197.4±2.9 | 0.008 | 194.1±4.0 | 204.2±3.2 | 0.050 |
HDL-C, mg/dL | 46.3±1.2 | 43.4±1.3 | 0.175 | 45.4±2.7 | 44.2±0.7 | 0.611 |
LDL-C, mg/dL | 128.2±3.4 | 121.9±2.3 | 0.138 | 117.2±2.9 | 126.1±2.5 | 0.021 |
TG, mg/dL | 174.1±10.5 | 166.2±5.9 | 0.489 | 158.7±7.2 | 176.1±7.1 | 0.101 |
Values are presented as number (%) or mean±standard error. NGT, normal glucose tolerance; BMI, body mass index; FBG, fasting blood glucose; HDL-C, high density lipoprotein cholesterol; LDL-C, low density lipoprotein cholesterol; TG, triglyceride.
Values are presented as number (%). NGT, normal glucose tolerance.
Values are presented as the mean±standard error. BMI, body mass index; HDL-C, high density lipoprotein cholesterol; LDL-C, low density lipoprotein cholesterol; TG, triglyceride.