Abstract

To evaluate the exocrine fnnction of the pancrea in diabetics, we measured the serum a- amylase, pancratic and salivary isoamylase activtty in 20 diabetics. The results are summarized as follows: 1) The mean serum a-amylase activity and pancreatic isoamylas activity were not differed between normal control and diabetics(p< 0.5, P* < 0. 5). 2) There was no significant correlatian between the duration of illness and serum pancreatic isoamyiase activity in diabetics (correlation coefficient 0.15, p<0.05). And there was slight positive correlation 'between the fasting blood, sugar level and the serum pancreatic isoamylase activity without statistical significance(correlation coefficient 0.36, p<0.5) 3) The serum a-amylase activity of the patint with diabetic ketoacidosis was much higher than that of normal control or other diabetics, and that was mainly due to elevation of the serum salivary isoamylase activity. These results suggest that the pancreatic exacrine function. Determined by serum isoamylase activity was normal in diabetics. .