Skip Navigation
Skip to contents

Diabetes Metab J : Diabetes & Metabolism Journal

Search
OPEN ACCESS

Articles

Page Path
HOME > Diabetes Metab J > Volume 33(1); 2009 > Article
Review Diabetic Cardiomyopathy.
Sung Ai Kim, Jong Won Ha
Diabetes & Metabolism Journal 2009;33(1):9-12
DOI: https://doi.org/10.4093/kdj.2009.33.1.9
Published online: February 1, 2009
  • 2,228 Views
  • 23 Download
  • 0 Crossref
  • 0 Scopus
Cardiology Division, Yonsei University College of Medicine, Seoul, Korea.
prev next

Cardiovascular disease is the most common cause of death in patients with diabetes mellitus (DM). In particular, the focus of many studies has been on ischemic heart disease, as it is a eading cause of death in diabetic patients. However, independent of coronary artery disease, DM can also lead to cardiac structural and functional changes, supporting the presence of diabetic cardiomyopathy. The pathologic mechanismin the development of diabetic cardiomyopathy is multifactorial including metabolic disturbance, myocardial fibrosis, microvascular disease, and autonomic dysfunction. Functionally, diabetic patients have a higher prevalence of LV (left ventricle) diastolic dysfunction. Because most diabetic patients with early myocardial disease have a wide spectrum of diastolic dysfunction at rest, assessment of LV functional reserve during exercise is helpful for early identification of myocardial dysfunction. Recent research has demonstrated that LV diastolic functional reserve (DFR) assessed by diastolic stress echocardiography was significantly reduced in patients with DM, compared with a control group, suggesting DFR might be an early indicator of diabetic cardiomyopathy. Glycemic control might be the most important and basic therapeutic strategy for preventing the development of diabetic cardiomyopathy. However, more extensive studies are needed to garner further evidence of preventive and therapeutic strategies of diabetic cardiomyopathy.

  • Cite
    CITE
    export Copy
    Close
    Download Citation
    Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.

    Format:
    • RIS — For EndNote, ProCite, RefWorks, and most other reference management software
    • BibTeX — For JabRef, BibDesk, and other BibTeX-specific software
    Include:
    • Citation for the content below
    Diabetic Cardiomyopathy.
    Korean Diabetes J. 2009;33(1):9-12.   Published online February 1, 2009
    Close
Related articles
Kim SA, Ha JW. Diabetic Cardiomyopathy.. Diabetes Metab J. 2009;33(1):9-12.
DOI: https://doi.org/10.4093/kdj.2009.33.1.9.

Diabetes Metab J : Diabetes & Metabolism Journal
Close layer
TOP