Diabetes Metab J > Volume 33(3); 2009 > Article
Korean Diabetes Journal 2009;33(3):251-256.
DOI: https://doi.org/10.4093/kdj.2009.33.3.251    Published online June 1, 2009.
Hypoglycemia due to Focal Nesidioblastosis in a Patient with Type 2 Diabetes Mellitus.
Eun Jung Lee, Kee Ho Song, Suk Kyeong Kim, Seong Hwan Chang, Dong Lim Kim
1Department of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea. dlkim@kuh.ac.kr
2Department of Surgery, Konkuk University School of Medicine, Seoul, Korea.
We report a 45-year-old man with type 2 diabetes who presented with recurrent hypoglycemia. Biochemical and imagingstudies did not show any mass-like lesion in the pancreas, so prednisolone and diazoxide were administered for the treatment of hypoglycemia. However, the hypoglycemia persisted during and after the medical treatment. A selective arterial calcium stimulation test was performed and revealed a suspicious lesion at the head of the pancreas. The patient underwent enucleation of the pancreas head lesion. The lesion was confirmed histologically to be focal nesidioblastosis and surgical resection was successfully performed. The patient showed no hypoglycemic symptoms postoperatively.
Key Words: Diabetes mellitus, Nesidioblastosis, Hypoglycemia

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