Skip Navigation
Skip to contents

Diabetes Metab J : Diabetes & Metabolism Journal

Search
OPEN ACCESS

Articles

Page Path
HOME > Diabetes Metab J > Volume 33(4); 2009 > Article
Original Article Effects of Vitamin D and Calcium Intervention on the Improvement of Resistance in Patients with Type 2 Diabetes Mellitus.
Young Mee Choi, Jun Ho Lee, Ji Sook Han
Diabetes & Metabolism Journal 2009;33(4):324-334
DOI: https://doi.org/10.4093/kdj.2009.33.4.324
Published online: August 1, 2009
  • 2,895 Views
  • 55 Download
  • 6 Crossref
  • 0 Scopus
1Department of Nutrition Care Services, Dong-eui Medical Center, Pusan, Korea.
2Department of Internal Medicine, Dong-eui Medical Center, Pusan, Korea.
3Department of Food Science and Nutrition, Research Institute of Ecology for The Elderly, Pusan National University, Pusan, Korea. hanjs@pusan.ac.kr
prev next

BACKGROUND
Recent reports suggest that the intake of vitamin D and calcium may influence insulin resistance. The aim of this study was to assess the effects of vitamin D and calcium intervention on the improvement of blood glucose and insulin resistance in patients with type 2 diabetes mellitus (DM). METHODS: Fasting blood glucose, glycosylated hemoglobin A1c (HbA1C), serum 25(OH)D3, serum lipid levels, insulin secretion, and activity and dietary surveys were analyzed in type 2 DM patients both before and after a 12-week vitamin D and calcium intake intervention. RESULTS: The serum 25(OH)D3 level was found to be negatively correlated with insulin resistance and fasting blood glucose. Calcium intake level was also negatively correlated with insulin resistance. Fasting blood glucose, HbA1C, and HOMA-IR decreased significantly (P <0.05) following vitamin D and calcium intake intervention in the medical nutrition therapy (MNT) group, while there was no such change observed in the control group. Dietary calcium and vitamin D intakes were significantly (P <0.05) higher in the MNT group than in the control group. The concentrations of serum 25(OH)D3 and insulin secretion increased slightly in the MNT group following the 12-week intervention; however, these results did not reach statistical significance. CONCLUSION: The results of the present study indicate that calcium and vitamin D intervention may be helpful in improving fasting blood glucose, HbA1C, serum 25(OH)D3 and HOMA-IR in patients with type 2 DM who have insufficient serum 25(OH)D3 concentrations.

  • Cite
    CITE
    export Copy
    Close
    Download Citation
    Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.

    Format:
    • RIS — For EndNote, ProCite, RefWorks, and most other reference management software
    • BibTeX — For JabRef, BibDesk, and other BibTeX-specific software
    Include:
    • Citation for the content below
    Effects of Vitamin D and Calcium Intervention on the Improvement of Resistance in Patients with Type 2 Diabetes Mellitus.
    Korean Diabetes J. 2009;33(4):324-334.   Published online August 1, 2009
    Close
Related articles
Choi YM, Lee JH, Han JS. Effects of Vitamin D and Calcium Intervention on the Improvement of Resistance in Patients with Type 2 Diabetes Mellitus.. Diabetes Metab J. 2009;33(4):324-334.
DOI: https://doi.org/10.4093/kdj.2009.33.4.324.

Diabetes Metab J : Diabetes & Metabolism Journal
Close layer
TOP