Clinical and Coronary Angiographic Findings of Coronary Artery Disease in Patients with Noninsulin Dependent Diabetes Mellitus.

Ku,  Bon Jeong; An,  Bong Soo; Jeong,  Jin Ok; Seong,  In Whan; Jeon,  Eun Seok; Shong,  Min Ho; Ro,  Heung Kyu; Kim,  Young Kun

Original Article

Korean Diabetes Journal 1997;21(3):308-313.
Published online January 1, 2001.

Clinical and Coronary Angiographic Findings of Coronary Artery Disease in Patients with Noninsulin Dependent Diabetes Mellitus.

Bon Jeong Ku, Bong Soo An, Jin Ok Jeong, In Whan Seong, Eun Seok Jeon, Min Ho Shong, Heung Kyu Ro, Young Kun Kim

Abstract

BACKGROUND
Diabetes mellitus has a major impact on cardiac morbidity and mortality. We analyzed the clinical characteristics and coronary angiographic findings in patients with a coronary artery disease and with noninsulin dependent diabetes mellitus. METHODS: We retrospectively reviewed the clinical and coronary angiographic findings in 74 patients with noninsulin dependent cliabetes mellitus and in 328 non-diabetic patients who had a coronary insufficiency. RESULTS: Significant coronary occlusions and multiple coronary artery diseases were more common in diabetics than in non-diabetics. The patients with noninsulin dependent diabetes mellitus has several limiting factors to perform the successful percutaneous coronary angioplasty, it could be a possible factor for rapid deterioration of coronary insufficiency in patients with diabetes mellitus. Smoking and hypertension significantly increased the incidence of signiftcant coronary occlusions whereas obesity and hypercholesterolemia did not any significant influence on incidence of the significant coronary occlusions. The longer duration of diabetes rnellitus associated with higher incidence of significant coronary occlusions and multiple coronary diseases. CONCLUSION: Significant coronary occlusions and multiple coronary artery diseases were occurred more common in diabetics than in non-diabetics. Coronary angiography should be performed routinely in noninsulin dependent diabetes.

Key Words: DM, Risk factor, Coronary artery disease