Fig. 1Urinary neutrophil gelatinase-associated lipocalin (NGAL) levels and glomerular filtration rate (GFR) in patients and healthy populations. (A) NGAL levels: 18.8 (1.3 to 81.9) ng/mL vs. 96.0 (2.7 to 975.2) ng/mL (P=0.02). (B) GFR: 49.3 (13.1 to 78.3) mL/min/1.73 m2 vs. 85.6 (72 to 106.7) mL/min/1.73 m2 (P<0.0001). CKD, chronic kidney disease.
Fig. 2Correlation analysis between glomerular filtration rate (GFR) and urinary neutrophil gelatinase-associated lipocalin (NGAL) in chronic kidney disease patients (r=-0.5634, P<0.0001).
Fig. 3Correlation analyses for urine protein and urinary neutrophil gelatinase-associated lipocalin (NGAL) levels and glomerular filtration rate (GFR) in chronic kidney disease patients. Correlations were analyzed between urinary protein level and urinary NGAL level (A) (r=0.3009, P=0.0256), urine protein and GFR (B) (r=-0.6245, P<0.0001), urine albumin and urinary NGAL (C) (r=0.1794, P=0.2275), and urine albumin and GFR (D) (r=-0.5190, P=0.0002).
Fig. 4Correlation between age (A) (r=-0.1488, P=0.3866), sex (B) (P=0.1823), and glomerular filtration rate (GFR) (C) (r=-0.2621, P=0.1226) and urinary neutrophil gelatinase-associated lipocalin (NGAL) in healthy populations.
Table 1Demographic data of 31 patients and 36 healthy individuals