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Adenoviruses Expressing PDX-1, BETA2/NeuroD and MafA Induces the Transdifferentiation of Porcine Neonatal Pancreas Cell Clusters and Adult Pig Pancreatic Cells into Beta-Cells |
Young-Hye You, Dong-Sik Ham, Heon-Seok Park, Marie Rhee, Ji-Won Kim, Kun-Ho Yoon |
Diabetes Metab J. 2011;35(2):119-129. Published online April 30, 2011 DOI: https://doi.org/10.4093/dmj.2011.35.2.119 |
Adenoviruses Expressing PDX-1, BETA2/NeuroD and MafA Induces the Transdifferentiation of Porcine Neonatal Pancreas Cell Clusters and Adult Pig Pancreatic Cells into Beta-Cells Generation of Insulin Expressing Cells in Mouse Small Intestine by Pdx1, MafA, and BETA2/NeuroD Generation of Functional Insulin-Producing Cells from Neonatal Porcine Liver-Derived Cells by PDX1/VP16, BETA2/NeuroD and MafA Generation of Insulin-Expressing Cells in Mouse Small Intestine by Pdx1, MafA, and BETA2/NeuroD Cell coupling regulates Ins1, Pdx-1 and MafA to promote insulin secretion in mouse pancreatic beta cells Xenogeneic pancreatic islet cell transplantation—Application of pig cells and techniques for clinical islet cell xenotransplantation Overexpression of BETA2/NeuroD induces neurite outgrowth in F11 neuroblastoma cells PDX-1/VP16 Overexpression Induce the Transdifferentiation of Canine Adult Pancreatic Cells into Beta-cells Neonatal pig pancreatic cell cluster accelerates regeneration of mouse pancreatic beta cells Transdifferentiation molecular pathways of neonatal pig pancreatic duct cells into endocrine cell phenotypes |