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| DA-1241, a Novel GPR119 Agonist, Improves Hyperglycaemia by Inhibiting Hepatic Gluconeogenesis and Enhancing Insulin Secretion in Diabetic Mice |
| Youjin Kim, Si Woo Lee, Hyejin Wang, Ryeong-Hyeon Kim, Hyun Ki Park, Hangkyu Lee, Eun Seok Kang |
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Diabetes Metab J. 2022;46(2):337-348. Published online January 21, 2022 DOI: https://doi.org/10.4093/dmj.2021.0056 |
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DA-1241, a Novel GPR119 Agonist, Improves Hyperglycaemia by Inhibiting Hepatic Gluconeogenesis and Enhancing Insulin Secretion in Diabetic Mice Diabetes & Metabolism Journal. 2022;46(2):337-348  1162-P: DA-1241, a Novel GPR119 Agonist, Improves Hyperglycaemia by Inhibiting Hepatic Gluconeogenesis and Enhancing Insulin Secretion via Stimulation of GLP-1 Secretion Diabetes. 2019;68(Supplement_1): 217-LB: A Novel GPR119 Agonist, DA-1241, Improves Hepatic Inflammation and Fibrosis in ob-NASH Mice Diabetes. 2020;69(Supplement_1): 216-LB: A Novel GPR119 Agonist, DA-1241, Reduces Hepatic Inflammation and Fibrosis in Preestablished Diet-Induced NASH Mice Diabetes. 2020;69(Supplement_1): Novel GPR119 agonist AS1669058 potentiates insulin secretion from rat islets and has potent anti-diabetic effects in ICR and diabetic db/db mice Life Sciences. 2013;92(2):167-173 Novel GPR119 agonist AS1535907 contributes to first-phase insulin secretion in rat perfused pancreas and diabetic db/db mice Biochemical and Biophysical Research Communications. 2010;402(2):280-285 Upregulated insulin secretion in insulin-resistant mice: evidence of increased islet GLP1 receptor levels and GPR119-activated GLP1 secretion Endocrine Connections. 2013;2(2):69-78 1285 HEPATIC PTEN DEFICIENCY TRIGGERS STEATOSIS DEVELOPMENT BUT IMPROVES GLUCOSE TOLERANCE BY INHIBITING HEPATIC GLUCONEOGENESIS AND INDUCING MUSCLE INSULIN HYPERSENSITIVITY Journal of Hepatology. 2013;58:S519-S520 Identification of a novel GPR119 agonist, AS1269574, with in vitro and in vivo glucose-stimulated insulin secretion Biochemical and Biophysical Research Communications. 2010;400(3):437-441 Red Pepper (Capsicum annuum L.) Seed Extract Improves Glycemic Control by Inhibiting Hepatic Gluconeogenesis via Phosphorylation of FOXO1 and AMPK in Obese Diabetic db/db Mice Nutrients. 2020;12(9):2546 |
