AMPK and Exercise: Glucose Uptake and Insulin Sensitivity
Hayley M. O'Neill (O'Neill HM)
Diabetes Metab J. 2013;37(1):1-21.   Published online 2013 Feb 15     DOI:
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Biomedicine & Pharmacotherapy.2019; 109: 1593.     CrossRef
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Ritu Varshney, Rutusmita Mishra, Neeladrisingha Das, Debabrata Sircar, Partha Roy
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Diabetes Research and Clinical Practice.2019; 156: 107092.     CrossRef
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Life Sciences.2018; 213: 226.     CrossRef
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Victor Castro, Marta Skowronska, Jorge Lombardi, Jane He, Neil Seth, Martina Velichkovska, Michal Toborek
Journal of Cerebral Blood Flow & Metabolism.2018; 38(2): 317.     CrossRef
Interactions between dietary carbohydrate and metformin: Implications on energy sensing, insulin signaling pathway, glycolipid metabolism and glucose tolerance in blunt snout bream Megalobrama amblycephala
Chao Xu, Wen-Bin Liu, Ding-Dong Zhang, Xiu-Fei Cao, Hua-Juan Shi, Xiang-Fei Li
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Aerobic exercise training decreases cereblon and increases AMPK signaling in the skeletal muscle of STZ-induced diabetic rats
Jeong Rim Ko, Dae Yun Seo, Se Hwan Park, Hyo Bum Kwak, Min Kim, Kyung Soo Ko, Byoung Doo Rhee, Jin Han
Biochemical and Biophysical Research Communications.2018; 501(2): 448.     CrossRef
AMPK in skeletal muscle function and metabolism
Rasmus Kjøbsted, Janne R. Hingst, Joachim Fentz, Marc Foretz, Maria‐Nieves Sanz, Christian Pehmøller, Michael Shum, André Marette, Remi Mounier, Jonas T. Treebak, Jørgen F. P. Wojtaszewski, Benoit Viollet, Louise Lantier
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Exercise improves glucose uptake in murine myotubes through the AMPKα2-mediated induction of Sestrins
Tianyi Wang, Yanmei Niu, Sujuan Liu, Hairui Yuan, Xiaolei Liu, Li Fu
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease.2018; 1864(10): 3368.     CrossRef
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Peng Wang, Lizhu Jiang, Nian Zhou, Hao Zhou, Huzhe Liu, Wenrui Zhao, Hanxiang Zhang, Xiang Zhang, Zhenming Hu
Oncotarget.2018; 9(9): 8427.     CrossRef
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Hojun Lee, Wook Song
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Vernonia cinerea water extract improves insulin resistance in high-fat diet–induced obese mice
Jarinyaporn Naowaboot, Supaporn Wannasiri, Patchareewan Pannangpetch
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Edward Archer, Gregory Pavela, Samantha McDonald, Carl J. Lavie, James O. Hill
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Hypothalamic AMPK as a Mediator of Hormonal Regulation of Energy Balance
Baile Wang, Kenneth Cheng
International Journal of Molecular Sciences.2018; 19(11): 3552.     CrossRef
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International Journal of Molecular Sciences.2018; 19(9): 2763.     CrossRef
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Siyuan Zhan, Wei Zhao, Tianzeng Song, Yao Dong, Jiazhong Guo, Jiaxue Cao, Tao Zhong, Linjie Wang, Li Li, Hongping Zhang
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Oyster mushroom functions as an anti-hyperglycaemic through phosphorylation of AMPK and increased expression of GLUT4 in type 2 diabetic model rats
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General and Comparative Endocrinology.2018; 267: 66.     CrossRef
Comprehensive Relevance of AMPK in Adaptive Responses of Physical Exercise, Skeletal Muscle and Neuromuscular Disorders
Jun-Ho Lee
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Interactive Roles for AMPK and Glycogen from Cellular Energy Sensing to Exercise Metabolism
Natalie Janzen, Jamie Whitfield, Nolan Hoffman
International Journal of Molecular Sciences.2018; 19(11): 3344.     CrossRef
Exercising with blocked muscle glycogenolysis: Adaptation in the McArdle mouse
Tue L. Nielsen, Tomàs Pinós, Astrid Brull, John Vissing, Thomas O. Krag
Molecular Genetics and Metabolism.2018; 123(1): 21.     CrossRef
Pharmacological activities of mogrosides
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Future Medicinal Chemistry.2018; 10(8): 845.     CrossRef
Structural Determinants for Small-Molecule Activation of Skeletal Muscle AMPK α2β2γ1 by the Glucose Importagog SC4
Kevin R.W. Ngoei, Christopher G. Langendorf, Naomi X.Y. Ling, Ashfaqul Hoque, Swapna Varghese, Michelle A. Camerino, Scott R. Walker, Ylva E. Bozikis, Toby A. Dite, Ashley J. Ovens, William J. Smiles, Roxane Jacobs, He Huang, Michael W. Parker, John W. Sc
Cell Chemical Biology.2018; 25(6): 728.     CrossRef
Fiber type-specific analysis of AMPK isoforms in human skeletal muscle: advancement in methods via capillary nanoimmunoassay
Irene S. Tobias, Kara K. Lazauskas, Jose A. Arevalo, James R. Bagley, Lee E. Brown, Andrew J. Galpin
Journal of Applied Physiology.2018; 124(4): 840.     CrossRef
Insulin Mimetic Activity of 3,4-Seco and Hexanordammarane Triterpenoids Isolated from Gynostemma longipes
Ha Thanh Tung Pham, Thi Kim Quy Ha, Hyo Moon Cho, Ba Wool Lee, Jin Pyo An, Van On Tran, Won Keun Oh
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Subcutaneous adipose tissue accumulation protects systemic glucose tolerance and muscle metabolism
A.D. Booth, A.M. Magnuson, J. Fouts, Y. Wei, D. Wang, M.J. Pagliassotti, M.T. Foster
Adipocyte.2018; 7(4): 261.     CrossRef
Host Adaptive Immune Status Regulates Expression of the Schistosome AMP-Activated Protein Kinase
Kasandra S. Hunter, Stephen J. Davies
Frontiers in Immunology.2018;[Epub]     CrossRef
Neurogenic obesity and systemic inflammation following spinal cord injury: A review
Gary J. Farkas, David R. Gater
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Progress in Cardiovascular Diseases.2018; 61(1): 10.     CrossRef
Anti-inflammatory effects induced by pharmaceutical substances on inflammatory active brain astrocytes—promising treatment of neuroinflammation
Elisabeth Hansson, Ulrika Björklund, Eva Skiöldebrand, Lars Rönnbäck
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Systemic pan-AMPK activator MK-8722 improves glucose homeostasis but induces cardiac hypertrophy
Robert W. Myers, Hong-Ping Guan, Juliann Ehrhart, Aleksandr Petrov, Srinivasa Prahalada, Effie Tozzo, Xiaodong Yang, Marc M. Kurtz, Maria Trujillo, Dinko Gonzalez Trotter, Danqing Feng, Shiyao Xu, George Eiermann, Marie A. Holahan, Daniel Rubins, Stacey C
Science.2017; 357(6350): 507.     CrossRef
Pioglitazone-induced bone loss in diabetic rats and its amelioration by berberine: A portrait of molecular crosstalk
Mohammad Adil, Mohd Nizam Mansoori, Divya Singh, Amit Dattatraya Kandhare, Manju Sharma
Biomedicine & Pharmacotherapy.2017; 94: 1010.     CrossRef
Rb2 inhibits α-glucosidase and regulates glucose metabolism by activating AMPK pathways in HepG2 cells
Hui Teng, Lei Chen, Ting Fang, Benyao Yuan, Qiyang Lin
Journal of Functional Foods.2017; 28: 306.     CrossRef
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Journal of Cardiovascular Pharmacology and Therapeutics.2017; 22(3): 219.     CrossRef
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Revista Colombiana de Médicina Física y Rehabilitación.2017; 27(2): 140.     CrossRef
Piperine regulates UCP1 through the AMPK pathway by generating intracellular lactate production in muscle cells
Nami Kim, Miso Nam, Mi Sun Kang, Jung Ok Lee, Yong Woo Lee, Geum-Sook Hwang, Hyeon Soo Kim
Scientific Reports.2017;[Epub]     CrossRef
Vitamin D supplementation inhibits oxidative stress and upregulate SIRT1/AMPK/GLUT4 cascade in high glucose-treated 3T3L1 adipocytes and in adipose tissue of high fat diet-fed diabetic mice
Prasenjit Manna, Arunkumar E. Achari, Sushil K. Jain
Archives of Biochemistry and Biophysics.2017; 615: 22.     CrossRef
Care of the Athlete With Type 1 Diabetes Mellitus: A Clinical Review
William B. Horton, Jose S. Subauste
International Journal of Endocrinology and Metabolism.2016;[Epub]     CrossRef
Cheonggukjang, a soybean paste fermented with B. licheniformis-67 prevents weight gain and improves glycemic control in high fat diet induced obese mice
Joo-Hee Choi, P.B.Tirupathi Pichiah, Min-Jung Kim, Youn-Soo Cha
Journal of Clinical Biochemistry and Nutrition.2016; 59(1): 31.     CrossRef
Rg3 Improves Mitochondrial Function and the Expression of Key Genes Involved in Mitochondrial Biogenesis in C2C12 Myotubes
Min Joo Kim, Young Do Koo, Min Kim, Soo Lim, Young Joo Park, Sung Soo Chung, Hak C. Jang, Kyong Soo Park
Diabetes & Metabolism Journal.2016; 40(5): 406.     CrossRef
Phytochemicals in regulating fatty acid β-oxidation: Potential underlying mechanisms and their involvement in obesity and weight loss
H.P. Vasantha Rupasinghe, Satvir Sekhon-Loodu, Theodora Mantso, Mihalis I. Panayiotidis
Pharmacology & Therapeutics.2016; 165: 153.     CrossRef
Insulin Signaling and Glucose Uptake in the Soleus Muscle of 30-Month-Old Rats After Calorie Restriction With or Without Acute Exercise
Haiyan Wang, Naveen Sharma, Edward B. Arias, Gregory D. Cartee
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences.2016; 71(3): 323.     CrossRef
Acute resistance exercise-induced IGF1 expression and subsequent GLUT4 translocation
Kohei Kido, Satoru Ato, Takumi Yokokawa, Yuhei Makanae, Koji Sato, Satoshi Fujita
Physiological Reports.2016; 4(16): e12907.     CrossRef
Regulation and function of AMPK in physiology and diseases
Sang-Min Jeon
Experimental & Molecular Medicine.2016; 48(7): e245.     CrossRef
Inhibiting stemness and invasive properties of glioblastoma tumorsphere by combined treatment with temozolomide and a newly designed biguanide (HL156A)
Junjeong Choi, Ji-Hyun Lee, Ilkyoo Koh, Jin-Kyoung Shim, Junseong Park, Jeong Yong Jeon, Mijin Yun, Se Hoon Kim, Jong In Yook, Eui Hyun Kim, Jong Hee Chang, Sun Ho Kim, Yong Min Huh, Su Jae Lee, Michael Pollak, Pilnam Kim, Seok-Gu Kang, Jae-Ho Cheong
Oncotarget.2016; 7(40): 65643.     CrossRef
[6]-Gingerol Affects Glucose Metabolism by Dual Regulation via the AMPKα2-Mediated AS160-Rab5 Pathway and AMPK-Mediated Insulin Sensitizing Effects
Jung Ok Lee, Nami Kim, Hye Jeong Lee, Ji Wook Moon, Soo Kyung Lee, Su Jin Kim, Joong Kwan Kim, Sun Hwa Park, Hyeon Soo Kim
Journal of Cellular Biochemistry.2015; 116(7): 1401.     CrossRef
A glance at … exercise and glucose uptake
Michael J. Glade, Kyl Smith
Nutrition.2015; 31(6): 893.     CrossRef
Exercising insulin sensitivity: AMPK turns on autophagy!
Yossi Dagon, Christos Mantzoros, Young-Bum Kim
Metabolism.2015; 64(6): 655.     CrossRef
Leucine supplementation does not affect protein turnover and impairs the beneficial effects of endurance training on glucose homeostasis in healthy mice
José M. Costa Júnior, Morgana R. Rosa, André O. Protzek, Flávia M. de Paula, Sandra M. Ferreira, Luiz F. Rezende, Emerielle C. Vanzela, Cláudio C. Zoppi, Leonardo R. Silveira, Isis C. Kettelhut, Antonio C. Boschero, Camila A. M. de Oliveira, Everardo M. C
Amino Acids.2015; 47(4): 745.     CrossRef
Endoplasmic reticulum chaperone GRP78 is involved in autophagy activation induced by ischemic preconditioning in neural cells
Xiang-Yang Zhang, Tong-Tong Zhang, Dan-Dan Song, Jun- Hao Zhou, Rong Han, Zheng-Hong Qin, Rui Sheng
Molecular Brain.2015;[Epub]     CrossRef
Identification of adenine modulating AMPK activation in NIH/3T3 cells by proteomic approach
Guang-Huar Young, Jiun-Tsai Lin, Yi-Fang Cheng, Chun-Fang Huang, Cheng-Yu Chao, Jing-Yi Nong, Po-Ku Chen, Han-Min Chen
Journal of Proteomics.2015; 120: 204.     CrossRef
Mechanisms for independent and combined effects of calorie restriction and acute exercise on insulin-stimulated glucose uptake by skeletal muscle of old rats
Naveen Sharma, Haiyan Wang, Edward B. Arias, Carlos M. Castorena, Gregory D. Cartee
American Journal of Physiology-Endocrinology and Metabolism.2015; 308(7): E603.     CrossRef
Human muscle fibre type-specific regulation of AMPK and downstream targets by exercise
Dorte E. Kristensen, Peter H. Albers, Clara Prats, Otto Baba, Jesper B. Birk, Jørgen F. P. Wojtaszewski
The Journal of Physiology.2015; 593(8): 2053.     CrossRef
Phenolic compounds ameliorate the glucose uptake in HepG2 cells' insulin resistance via activating AMPK
Qun Huang, Lei Chen, Hui Teng, Hongbo Song, Xiaoqi Wu, Meiyu Xu
Journal of Functional Foods.2015; 19: 487.     CrossRef
Celastrol Protects against Antimycin A-Induced Insulin Resistance in Human Skeletal Muscle Cells
Mohamad Abu Bakar, Kian-Kai Cheng, Mohamad Sarmidi, Harisun Yaakob, Hasniza Huri
Molecules.2015; 20(5): 8242.     CrossRef
Glucose uptake in human brown adipose tissue is impaired upon fasting-induced insulin resistance
Mark J. W. Hanssen, Roel Wierts, Joris Hoeks, Anne Gemmink, Boudewijn Brans, Felix M. Mottaghy, Patrick Schrauwen, Wouter D. van Marken Lichtenbelt
Diabetologia.2015; 58(3): 586.     CrossRef
Skeletal muscle ACC2 S212 phosphorylation is not required for the control of fatty acid oxidation during exercise
Hayley M. O'Neill, James S. Lally, Sandra Galic, Thomas Pulinilkunnil, Rebecca J. Ford, Jason R. B. Dyck, Bryce J. van Denderen, Bruce E. Kemp, Gregory R. Steinberg
Physiological Reports.2015; 3(7): e12444.     CrossRef
Adenosine Monophosphate–Activated Kinase and Its Key Role in Catabolism: Structure, Regulation, Biological Activity, and Pharmacological Activation
Sukriti Krishan, Des R. Richardson, Sumit Sahni
Molecular Pharmacology.2015; 87(3): 363.     CrossRef
Role of AMPK and PPARγ1 in exercise-induced lipoprotein lipase in skeletal muscle
Takashi Sasaki, Rieko Nakata, Hiroyasu Inoue, Makoto Shimizu, Jun Inoue, Ryuichiro Sato
American Journal of Physiology-Endocrinology and Metabolism.2014; 306(9): E1085.     CrossRef
A novel heterozygous mutation in the glucokinase gene conferring exercise-induced symptomatic hyperglycaemia responsive to sulfonylurea
M.S.E. Ebrahim, M.L. Lawson, M.T. Geraghty
Diabetes & Metabolism.2014; 40(4): 310.     CrossRef
Anti-obesity and anti-insulin resistance effects of tomato vinegar beverage in diet-induced obese mice
Kwon-Il Seo, Jin Lee, Ra-Yeong Choi, Hae-In Lee, Ju-Hye Lee, Yong-Ki Jeong, Myung-Joo Kim, Mi-Kyung Lee
Food & Function.2014; 5(7): 1579.     CrossRef
The AMPK-SIRT signaling network regulates glucose tolerance under calorie restriction conditions
M.F.P. Silvestre, B. Viollet, P.W. Caton, J. Leclerc, I. Sakakibara, M. Foretz, M.C. Holness, M.C. Sugden
Life Sciences.2014; 100(1): 55.     CrossRef
Calanquinone A induces anti-glioblastoma activity through glutathione-involved DNA damage and AMPK activation
Fan-Lun Liu, Jui-Ling Hsu, Yean-Jang Lee, Yu-Shun Dong, Fan-Lu Kung, Ching-Shih Chen, Jih-Hwa Guh
European Journal of Pharmacology.2014; 730: 90.     CrossRef
Fighting obesity: When muscle meets fat
Xin Yang, Pengpeng Bi, Shihuan Kuang
Adipocyte.2014; 3(4): 280.     CrossRef
Quercetin attenuates renal ischemia/reperfusion injury via an activation of AMP-activated protein kinase-regulated autophagy pathway
Bo-Lin Chen, Li-Ting Wang, Kuo-How Huang, Ching-Chia Wang, Chih-Kang Chiang, Shing-Hwa Liu
The Journal of Nutritional Biochemistry.2014; 25(11): 1226.     CrossRef
AMPK controls exercise endurance, mitochondrial oxidative capacity, and skeletal muscle integrity
Louise Lantier, Joachim Fentz, Rémi Mounier, Jocelyne Leclerc, Jonas T. Treebak, Christian Pehmøller, Nieves Sanz, Iori Sakakibara, Emmanuelle Saint‐Amand, Stéphanie Rimbaud, Pascal Maire, André Marette, Renée Ventura‐Clapier, Arnaud Ferry, Jørgen F. P. W
The FASEB Journal.2014; 28(7): 3211.     CrossRef
Activation of AMPKα2 Is Not Crucial for Mitochondrial Uncoupling-Induced Metabolic Effects but Required to Maintain Skeletal Muscle Integrity
Mario Ost, Franziska Werner, Janine Dokas, Susanne Klaus, Anja Voigt, Juergen Eckel
PLoS ONE.2014; 9(4): e94689.     CrossRef
Thioredoxin-interacting protein mediates hepatic lipogenesis and inflammation via PRMT1 and PGC-1α regulation in vitro and in vivo
Min-Jung Park, Dong-Il Kim, Seul-Ki Lim, Joo-Hee Choi, Jong-Choon Kim, Kyung-Chul Yoon, Jee-Bum Lee, Jae-Hyuk Lee, Ho-Jae Han, In-Pyo Choi, Hyoung-Chin Kim, Soo-Hyun Park
Journal of Hepatology.2014; 61(5): 1151.     CrossRef
Liraglutide enhances glucose transporter 4 translocation via regulation of AMP-activated protein kinase signaling pathways in mouse skeletal muscle cells
Zhu Li, Chang-Lin Ni, Zhi Yao, Li-Ming Chen, Wen-Yan Niu
Metabolism.2014; 63(8): 1022.     CrossRef
Effects of metformin on weight loss
Steven K. Malin, Sangeeta R. Kashyap
Current Opinion in Endocrinology, Diabetes & Obesity.2014; 21(5): 323.     CrossRef
Changes of Blood Glucose and Lactate Concentration in Body Wearing Firefighting Protective Equipments
Chang-Hoon Bang
Journal of Korean Society of Hazard Mitigation.2014; 14(1): 263.     CrossRef
The Effects of Exercise Training on Obesity-Induced Dysregulated Expression of Adipokines in White Adipose Tissue
Takuya Sakurai, Junetsu Ogasawara, Takako Kizaki, Shogo Sato, Yoshinaga Ishibashi, Motoko Takahashi, Osamu Kobayashi, Shuji Oh-ishi, Junichi Nagasawa, Kazuto Takahashi, Hitoshi Ishida, Tetsuya Izawa, Hideki Ohno
International Journal of Endocrinology.2013; 2013: 1.     CrossRef
Flavonoids from Tetrastigma obtectum enhancing glucose consumption in insulin-resistance HepG2 cells via activating AMPK
Mei-Na Jin, Guo-Ru Shi, Sheng-An Tang, Nan-Qin, Wei Qiao, Hong-Quan Duan
Fitoterapia.2013; 90: 240.     CrossRef
AMPK, insulin resistance, and the metabolic syndrome
Neil B. Ruderman, David Carling, Marc Prentki, José M. Cacicedo
Journal of Clinical Investigation.2013; 123(7): 2764.     CrossRef
Resistance to Dasatinib in primary chronic lymphocytic leukemia lymphocytes involves AMPK-mediated energetic re-programming
Veronica Martinez Marignac, Sarah Smith, Nader Toban, Miguel Bazile, Raquel Aloyz
Oncotarget.2013; 4(12): 2550.     CrossRef
Improvement of vascular insulin sensitivity by downregulation of GRK2 mediates exercise-induced alleviation of hypertension in spontaneously hypertensive rats
Wenjuan Xing, Youyou Li, Haifeng Zhang, Chunjuan Mi, Zuoxu Hou, Michael J. Quon, Feng Gao
American Journal of Physiology-Heart and Circulatory Physiology.2013; 305(8): H1111.     CrossRef
AMP-activated protein kinase activation mediates CCL3-induced cell migration and matrix metalloproteinase-2 expression in human chondrosarcoma
Chin-Jung Hsu, Min-Huan Wu, Chin-Yuan Chen, Chun-Hao Tsai, Horng-Chaung Hsu, Chih-Hsin Tang
Cell Communication and Signaling.2013;[Epub]     CrossRef