Diabetes & Metabolism Journal

Review

Cardiovascular Risk/Epidemiology
Artificial Light at Night and Type 2 Diabetes Mellitus: Jong-Ha Baek, Yong Zhu, Chandra L. Jackson, Yong-Moon Mark Park; Diabetes Metab J. 2024;48(5):847-863. Published online September 12, 2024; DOI: https://doi.org/10.4093/dmj.2024.0237

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Abstract PDF PubReader ePub: The widespread and pervasive use of artificial light at night (ALAN) in our modern 24-hour society has emerged as a substantial disruptor of natural circadian rhythms, potentially leading to a rise in unhealthy lifestyle-related behaviors (e.g., poor sleep; shift work). This phenomenon has been associated with an increased risk of type 2 diabetes mellitus (T2DM), which is a pressing global public health concern. However, to date, reviews summarizing associations between ALAN and T2DM have primarily focused on the limited characteristics of exposure (e.g., intensity) to ALAN. This literature review extends beyond prior reviews by consolidating recent studies from 2000 to 2024 regarding associations between both indoor and outdoor ALAN exposure and the incidence or prevalence of T2DM. We also described potential biological mechanisms through which ALAN modulates glucose metabolism. Furthermore, we outlined knowledge gaps and investigated how various ALAN characteristics beyond only light intensity (including light type, timing, duration, wavelength, and individual sensitivity) influence T2DM risk. Recognizing the detrimental impact of ALAN on sleep health and the behavioral correlates of physical activity and dietary patterns, we additionally summarized studies investigating the potential mediating role of each component in the relationship between ALAN and glucose metabolism. Lastly, we proposed implications of chronotherapies and chrononutrition for diabetes management in the context of ALAN exposure.

Original Articles

Complications
Association between Sleep Quality and Painless Diabetic Peripheral Neuropathy Assessed by Current Perception Threshold in Type 2 Diabetes Mellitus: Dughyun Choi, Bo-Yeon Kim, Chan-Hee Jung, Chul-Hee Kim, Ji-Oh Mok; Diabetes Metab J. 2021;45(3):358-367. Published online August 6, 2020; DOI: https://doi.org/10.4093/dmj.2019.0219

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Graphical Abstract Abstract PDF Supplementary Material PubReader ePub

Background

It is known that the painful sensation of diabetic peripheral neuropathy (DPN) results in sleep problems in type 2 diabetes mellitus (T2DM). However, it is not known that the painless DPN also is associated with poor sleep quality in T2DM. The purpose of the current study was to investigate the association between painless DPN and poor sleep quality in T2DM.

Methods

A total of 146 patients of T2DM who do not have any painful symptoms of DPN were recruited into the study. Among the patients, painless DPN was diagnosed by using the current perception threshold test. Sleep quality was assessed using the Pittsburgh Sleep Quality Index questionnaire.

Results

The percentage of painless DPN was significantly higher in the poor sleep quality group than the good sleep quality group (70.0% vs. 35.5%, P<0.001). In the subscale results, stimulus values at 2,000 Hz, hypoesthesia and hyperesthesia were more common in the poor sleep quality group than in the good sleep quality group (45.7% vs. 25.0%, P=0.009; 34.3% vs. 18.4%, P=0.029; 40.0% vs. 19.7%, P=0.007, respectively). The association of painless DPN and poor sleep quality remained significant after adjustment for significant covariates (odds ratio, 3.825; 95% confidence interval, 1.674 to 8.742; P<0.001).

Conclusion

The current study showed that painless DPN was associated with poor sleep quality. Future studies are required to clarify the pathophysiologic causal relationship between painless DPN and sleep quality.

Citations

Citations to this article as recorded by

Deteriorated sleep quality and associate factors in patients with type 2 diabetes mellitus complicated with diabetic peripheral neuropathy
Lin Fu, Liping Zhong, Xin Liao, Lingrui Wang, Youyi Wang, Xiuquan Shi, Yanna Zhou
PeerJ.2024; 12: e16789. CrossRef
Sleep impairment: Is it an overlooked burden in painful diabetic peripheral neuropathy? A single-centre, cross-sectional study from south India
Adlin Lawrence, Himsikhar Khataniar, Sinimol Joseph, Thenmozhi Nagarajan, Soumya Umesh, John Michael Raj A
Diabetes & Metabolic Syndrome: Clinical Research & Reviews.2022; 16(8): 102568. CrossRef
Sleep: an emerging therapeutic target in diabetes care
Nishant Raizada, S. V. Madhu
International Journal of Diabetes in Developing Countries.2021; 41(1): 1. CrossRef

Complications
Deterioration of Sleep Quality According to Glycemic Status: Myung Haeng Hur, Mi-Kyoung Lee, Kayeon Seong, Jun Hwa Hong; Diabetes Metab J. 2020;44(5):679-686. Published online April 17, 2020; DOI: https://doi.org/10.4093/dmj.2019.0125

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Abstract PDF Supplementary Material PubReader ePub

Background

Type 2 diabetes mellitus (T2DM) is a progressive disease with multiple complications. The present study aimed to determine the effects of glycemic status on sleep quality in individuals with T2DM, prediabetes, and normal glucose tolerance (NGT).

Methods

A total of 90 participants were categorized into three groups, T2DM (n=30), prediabetes (n=30), and NGT (n=30). Objective sleep quality was measured with the actigraph wrist-worn device over 3 nights and subjective sleep quality was evaluated with a questionnaire.

Results

The duration of diabetes in the T2DM group was 2.23 years and the glycosylated hemoglobin (HbA1c) levels in the T2DM, prediabetes, and NGT groups were 7.83%, 5.80%, and 5.31%, respectively. Sleep efficiency decreased across the T2DM, prediabetes, and NGT groups (86.25%, 87.99%, and 90.22%, respectively; P=0.047). Additionally, HbA1c levels revealed a significant negative correlation with sleep efficiency (r=−0.348, P=0.001). The sleep quality questionnaire results were similar among the three groups.

Conclusion

Although the participants in the present study were not necessarily conscious of their sleep disturbances, deterioration in sleep quality progressed according to glycemic status.

Citations

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Reviews

Obesity and Metabolic Syndrome
Metabolic Consequences of Obstructive Sleep Apnea Especially Pertaining to Diabetes Mellitus and Insulin Sensitivity: Sun Ok Song, Ken He, Radhika R. Narla, Hyun Goo Kang, Han Uk Ryu, Edward J. Boyko; Diabetes Metab J. 2019;43(2):144-155. Published online April 15, 2019; DOI: https://doi.org/10.4093/dmj.2018.0256

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Abstract PDF PubReader

Obstructive sleep apnea (OSA) and diabetes has been known to be closely related to each other and both diseases impact highly on the public health. There are many evidence of reports that OSA is associated with diabetes with a bidirectional correlation. A possible causal mechanism of OSA to diabetes is intermittent hypoxemia and diabetes to OSA is microvascular complication. However, OSA and diabetes have a high prevalence rate in public and shares the common overlap characteristic and risk factors such as age, obesity, and metabolic syndrome that make it difficult to establish the exact pathophysiologic mechanism between them. In addition, studies demonstrating that treatment of OSA may help prevent diabetes or improve glycemic control have not shown convincing result but have become a great field of interest research. This review outlines the bidirectional correlation between OSA and diabetes and explore the pathophysiologic mechanisms by approaching their basic etiologies.

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The Laryngoscope.2024; 134(4): 1978. CrossRef
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International Journal of Molecular Sciences.2024; 25(6): 3243. CrossRef
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Nature and Science of Sleep.2024; Volume 16: 517. CrossRef
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World Journal of Diabetes.2024; 15(7): 1448. CrossRef
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Nature and Science of Sleep.2024; Volume 16: 1515. CrossRef
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Clinical Endocrinology.2023; 98(1): 3. CrossRef
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Journal of Sleep Research.2023;[Epub] CrossRef
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Nigerian Journal of Clinical Practice.2023; 26(10): 1423. CrossRef
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Obstructive Sleep Apnea and Abnormal Glucose Metabolism: Nan Hee Kim; Diabetes Metab J. 2012;36(4):268-272. Published online August 20, 2012; DOI: https://doi.org/10.4093/dmj.2012.36.4.268

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Abstract PDF PubReader

Obstructive sleep apnea (OSA) is a chronic disorder that is prevalent, especially in subjects with obesity or diabetes. OSA is related to several metabolic abnormalities, including diabetes, insulin resistance, hypertension, and cardiovascular diseases. Although Koreans are less obese than Caucasians, the prevalence of OSA is comparable in both groups. Thus, the impact of OSA on metabolism may be similar. Many epidemiologic and experimental studies have demonstrated that OSA is associated with glucose intolerance and insulin resistance via intermittent hypoxia, sleep fragmentation, and sleep deprivation. The effect of continuous positive airway pressure treatment on glucose metabolism is still controversial. Randomized controlled trials are needed to evaluate the ability of OSA treatment to reduce the risk of diabetes and insulin resistance in subjects without diabetes and to ameliorate glucose control in patients with diabetes.

Citations

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Clinical Nutrition ESPEN.2021; 42: 82. CrossRef
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Sina Akbarian, Nasim Montazeri Ghahjaverestan, Azadeh Yadollahi, Babak Taati
Journal of Medical Internet Research.2021; 23(11): e26524. CrossRef
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Sina Akbarian, Nasim Montazeri Ghahjaverestan, Azadeh Yadollahi, Babak Taati
Journal of Medical Internet Research.2020; 22(5): e17252. CrossRef
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Suhas S. Khaire, Jugal V. Gada, Ketaki V. Utpat, Nikita Shah, Premlata K. Varthakavi, Nikhil M. Bhagwat
Clinical Diabetes and Endocrinology.2020;[Epub] CrossRef
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Alessio Pecori, Fabrizio Buffolo, Jacopo Pieroni, Vittorio Forestiero, Elisa Sconfienza, Franco Veglio, Paolo Mulatero, Silvia Monticone
Hormone and Metabolic Research.2020; 52(06): 366. CrossRef
Automated Non-Contact Detection of Head and Body Positions During Sleep
Sina Akbarian, Ghazaleh Delfi, Kaiyin Zhu, Azadeh Yadollahi, Babak Taati
IEEE Access.2019; 7: 72826. CrossRef
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Ji A Seo, Da Young Lee, Ji Hee Yu, Hyunjoo Cho, Seung Ku Lee, Sooyeon Suh, Sin Gon Kim, Kyung Mook Choi, Sei Hyun Baik, Chol Shin, Nan Hee Kim
Sleep.2019;[Epub] CrossRef
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Tetiana V Serebrovska, Alla G Portnychenko, Tetiana I Drevytska, Vladimir I Portnichenko, Lei Xi, Egor Egorov, Anna V Gavalko, Svitlana Naskalova, Valentina Chizhova, Valeriy B Shatylo
Experimental Biology and Medicine.2017; 242(15): 1542. CrossRef
Features of continuous glycemic profile and glycemic variability in patients with obstructive sleep apnea syndrome
Chao-Sheng Peng, Yue-An Cao, Yu-Hong Tian, Wen-Luo Zhang, Jing Xia, Lu Yang
Diabetes Research and Clinical Practice.2017; 134: 106. CrossRef
Acute Hypoxic Test in Patients with Prediabetes
Valerii B. Shatylo, Tatiana V. Serebrovska, Anna V. Gavalko, Egor Egorov, Oleg V. Korkushko
High Altitude Medicine & Biology.2016; 17(2): 101. CrossRef
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The Korean Journal of Internal Medicine.2015; 30(6): 846. CrossRef
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Obesity and metabolism.2015; 12(2): 24. CrossRef
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Original Article

Prevalence and Correlates of Disordered Sleep in Southeast Asian Indians with Type 2 Diabetes: Amarabalan Rajendran, Shruthi Parthsarathy, Bubblu Tamilselvan, Krishna G. Seshadri, Mohamed Shuaib; Diabetes Metab J. 2012;36(1):70-76. Published online February 17, 2012; DOI: https://doi.org/10.4093/dmj.2012.36.1.70

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Background

Sleep disturbances are common in individuals with diabetes. Patients with diabetes have higher rates of insomnia, excessive daytime sleepiness and increased incidence of restless leg syndrome. The purpose of our study was to investigate the prevalence and determine the predictors of sleep dysfunction in patients with type 2 diabetes in a southeast Asian Indian population.

Methods

We enrolled 120 patients with type 2 diabetes who attended an endocrinology clinic in a tertiary-care hospital. After we collected their demographic data, we recorded their anthropometric measurements. Fasting, postprandial blood glucose values and glycosylated hemoglobin (HbA1c) values were then obtained. Quality of sleep was evaluated in all the patients through the Pittsburgh Sleep Quality Index (PSQI), which is a questionnaire that assesses sleep quality and disturbances over a monthlong period. A Global Sleep Quality score ≥5 discriminates between good and poor sleepers.

Results

The mean global PSQI score was 7.08 (standard deviation, 3.89), which suggested poor sleep quality in this population. Sixty-nine percent of patients had a global PSQI score ≥5, indicating that they were "poor sleepers." The global PSQI score positively correlated with the duration of diabetes and was also independent of other variables such as age, gender, body mass index, HbA1c, or medications.

Conclusion

We found a high prevalence of sleep dysfunction in patients with type 2 diabetes. We also found a significant correlation between duration of diabetes and quality of sleep, independent of other variables. It is important for physicians to address the quality and duration of sleep in patients with type 2 diabetes.

Citations

Citations to this article as recorded by

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