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Clinical Characteristics of Diabetic Patients Controlled by Diet and Exercise.
Kil Sang Wang, Sung Bae Lee, Hyun Suk Lee, Jae Suk Jeon, Kyung Wan Min, Kyung Ah Han, Eung Jin Kim
Korean Diabetes J. 1999;23(1):98-107.   Published online January 1, 2001
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BACKGROUND
In order to rnaintain blood glucose in ao acceptable range, some patients with type 2 diabetes mellitus may be able to their level manage with diet and exercise alone, but others require oral agents or insulin. To assess which factors gave important influences on therapeutic methocls, we investigated clinical characteristics and life-style in the type 2 diabetic patients who could be managed with diet and exercise alone. METHODS: We recruited patients with type 2 diabetes mellitus from Eulji Medical College Diabetes Center, who had dieted and exercised for over 3 years (99; group 1) and compared them with patients who were managed with oral agents (130; group 2) or insulin (47; group 3). We conducted the retrospective evaluation of age, sex, duration of DM, initial and recent BM1 (body mass index), serial HbA 1c, skipped period ratio of hospital follow-up, self monitoring of blood glucose (SMBG) or urine sugar, diet and exercise and educational chance for diabetes with dependency of folk remedies. RESULTS: The duration of the DM was significantly shorter in group 1 than in group 2 or 3 (p<0,05). Initial BMI and HbA. were not different among these three groups, but HMI reduction was more decreased in group 1 (p<0.05). The mean HbA, during follow-up was lower in group 1 (p<0.05). The skipped period ratio of hospital follow-up was lower in group 1 (p<0.05). SMBG was less frequent, the meal-time was more regular, extra-snacks were less frequent and folk remedies were rarely tried in group 1. CONCLUSION: This study suggests that the duration of DM, BMI reduction and mean HbA 1c, were associated with the therapeutic method in patients with type 2 diabetes mellitus. We would like to a]so emphasize the importance of SMBG, meal-time regularity, extra-snacks and folk remedies in the education of patients with type 2 diabetes mellitus.
Fasting Serum Insulin Levels in Relation to Age and Body Mass Index and Serum Glucose Level in Healthy Subjects in Korea.
Sang Ah Chang, Ho Young Son, Bong Yun Cha, Sung Dae Moon, Ki Ho Song, Soon Jib Yoo, Kun Ho Yoon, Moo Il Kang, Kwang Woo Lee, Sung Ku Kang
Korean Diabetes J. 1997;21(4):433-443.   Published online January 1, 2001
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AbstractAbstract PDF
BACKGROUND
Ethnic variability in the relationship between glucose tolerance and insulin secretion has been reported. Clinical characteristics of Korean diabetic patients are different from that of diabetic patients in Western countries. It is generally assumed that typical IDDM or obese diabetic patients are relatively rare among Korean subjects. This study attempted to define the characteristics of fasting serum insulin levels of healthy Korean adult subjects. Futhermore, we tried to evaluate the relationship between fasting serum insulin level and age, body mass index, serum glucose. METHODS: We examined 1917 Korean subjects who had fasting blood glucose within normal range (3.6~6.4mmol/L). The fasting insulin levels, total choiesterol, triglyceride concentrations and anthropometric characteristics(body weight, height and body mass index(BMI)) of these subjects were measured. RESULTS: 1) Mean fasting insulin levels were 33.9+0.5pmol/ L, the fasting insulin levels in men and women were 34.9+0.6 and 31.8+0.6pmol/L, respectively. 2) The fasting insulin levels of obese(BMI>25) subjects were significantly higher than those of non-obese subjects(43.2+ 1.2 pmol/L vs. 30.6+0.6 pmol/L, p<0.001). 3) There were significant differences in the basal insulin levels among the age groups, and fasting blood glucose levels were increased with aging. 4) In a multiple stepwise regression analysis, insulin levels were positively correlated with serum triglycerides, fasting blood glucose, body mass index and negatively correlated with age. Conclusion : The fasting insulin levels of healthy subjects in Korea were relatively lower than the previously measured value of Caucasians. The insulin levels were decreased with aging and increased with the elevation of BMI, fasting blood glucose and triglyceride.

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