Skip Navigation
Skip to contents

Diabetes Metab J : Diabetes & Metabolism Journal

Search
OPEN ACCESS

Search

Page Path
HOME > Search
1 "Shriram Nallamshetty"
Filter
Filter
Article category
Keywords
Publication year
Authors
Original Article
Obesity and Metabolic Syndrome
Increased Risk of Progression of Coronary Artery Calcification in Male Subjects with High Baseline Waist-to-Height Ratio: The Kangbuk Samsung Health Study
Hyung-Geun Oh, Shriram Nallamshetty, Eun-Jung Rhee
Diabetes Metab J. 2016;40(1):54-61.   Published online February 19, 2016
DOI: https://doi.org/10.4093/dmj.2016.40.1.54
  • 3,654 View
  • 29 Download
  • 10 Web of Science
  • 12 Crossref
AbstractAbstract PDFPubReader   
Background

The waist-to-height ratio (WHtR) is an easy and inexpensive adiposity index that reflects central obesity. In this study, we examined the association of baseline WHtR and progression of coronary artery calcification (CAC) over 4 years of follow-up in apparently healthy Korean men.

Methods

A total of 1,048 male participants (mean age, 40.9 years) in a health-screening program in Kangbuk Samsung Hospital, Seoul, Korea who repeated a medical check-up in 2010 and 2014 were recruited. Baseline WHtR was calculated using the value for the waist in 2010 divided by the value for height in 2010. The CAC score (CACS) of each subject was measured by multi-detector computed tomography in both 2010 and 2014. Progression of CAC was defined as a CACS change over 4 years greater than 0.

Results

During the follow-up period, progression of CAC occurred in 278 subjects (26.5%). The subjects with CAC progression had slightly higher but significant baseline WHtR compared to those who did not show CAC progression (0.51±0.04 vs. 0.50±0.04, P<0.01). The proportion of subjects with CAC progression significantly increased as the baseline WHtR increased from the 1st quartile to 4th quartile groups (18.3%, 18.7%, 28.8%, and 34.2%; P<0.01). The risk for CAC progression was elevated with an odds ratio of 1.602 in the 4th quartile group of baseline WHtR even after adjustment for confounding variables (95% confidence interval, 1.040 to 2.466).

Conclusion

Increased baseline WHtR was associated with increased risk for CAC progression. WHtR might be a useful screening tool to identify individuals at high risk for subclinical atherosclerosis.

Citations

Citations to this article as recorded by  
  • Nicotine dependence and visceral adiposity as risk factors for the development and severity of carotid artery stenosis
    Mahmood Shaker Khazaal, Farqad Bader Hamdan, Qasim Sharhan Al-Mayah
    Journal of Medicine and Life.2023; 16(3): 463.     CrossRef
  • Differences in the number of stented coronary arteries based on the seven traditional obesity parameters among patients with coronary artery diseases undergoing cardiac catheterization
    Audai A Hayajneh, Islam M Alhusban, Mohammad Rababa, Sami Al-Rawashdeh, Shatha Al-Sabbah, Dania Bani-Hamad
    Electronic Journal of General Medicine.2022; 19(5): em391.     CrossRef
  • Predictive Model for High Coronary Artery Calcium Score in Young Patients with Non-Dialysis Chronic Kidney Disease
    Tae Ryom Oh, Su Hyun Song, Hong Sang Choi, Sang Heon Suh, Chang Seong Kim, Ji Yong Jung, Kyu Hun Choi, Kook-Hwan Oh, Seong Kwon Ma, Eun Hui Bae, Soo Wan Kim
    Journal of Personalized Medicine.2021; 11(12): 1372.     CrossRef
  • Computed tomography calcium scoring association and reclassification of clinical cardiovascular risk in asymptomatic Mexican patients
    Aldo Javier Vázquez Mézquita, Michelle Claire Williams, Rafael Choza Chenhalls, Nancy Berenice Guzmán Martínez, Ana Patricia Chischistz Condey, Maria José Acosta Falomir, Marco Antonio Téliz Meneses, María Nayeli Vázquez Sánchez
    SAGE Open Medicine.2020; 8: 205031212093823.     CrossRef
  • The association of waist-to-height ratio and other anthropometric measurements with subclinical atherosclerosis: Results from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)
    Rosana Raele, Paulo A. Lotufo, Marcio S. Bittencourt, Maria de Jesus M. Fonseca, Alessandra C. Goulart, Itamar S. Santos, Isabela M. Bensenor
    Nutrition, Metabolism and Cardiovascular Diseases.2020; 30(11): 1989.     CrossRef
  • The Risk of Myocardial Infarction and Ischemic Stroke According to Waist Circumference in 21,749,261 Korean Adults: A Nationwide Population-Based Study
    Jung-Hwan Cho, Eun-Jung Rhee, Se-Eun Park, Hyemi Kwon, Jin-Hyung Jung, Kyung-Do Han, Yong-Gyu Park, Hye Soon Park, Yang-Hyun Kim, Soon-Jib Yoo, Won-Young Lee
    Diabetes & Metabolism Journal.2019; 43(2): 206.     CrossRef
  • Being Metabolically Healthy, the Most Responsible Factor for Vascular Health
    Eun-Jung Rhee
    Diabetes & Metabolism Journal.2018; 42(1): 19.     CrossRef
  • The renal tubular damage marker urinary N-acetyl-β-d-glucosaminidase may be more closely associated with early detection of atherosclerosis than the glomerular damage marker albuminuria in patients with type 2 diabetes
    So Ra Kim, Yong-ho Lee, Sang-Guk Lee, Eun Seok Kang, Bong-Soo Cha, Byung-Wan Lee
    Cardiovascular Diabetology.2017;[Epub]     CrossRef
  • Influencia de la actividad física y el consumo calórico sobre la adiposidad visceral en adultos de la ciudad de Cuenca, Ecuador
    Rina Ortiz, Maritza Torres, Wilson Siguencia, Nube Sigüenza-Cobos, Juan Salazar, Roberto Añez, Joselyn Rojas, Valmore Bermúdez
    Revista Argentina de Endocrinología y Metabolismo.2017; 54(4): 160.     CrossRef
  • The association between various indices of obesity and severity of atherosclerosis in adults in the north of Iran
    Arsalan Salari, Maryam Shakiba, Marjan Mahdavi-Roshan, Mahboobeh Gholipour, Moona Naghshbandi, Ramin Rajabi
    Medicine.2016; 95(50): e5670.     CrossRef
  • Diet Quality and Mortality Risk in Metabolically Obese Normal-Weight Adults
    Yong-Moon Mark Park, Teresa T. Fung, Susan E. Steck, Jiajia Zhang, Linda J. Hazlett, Kyungdo Han, Seung-Hwan Lee, Anwar T. Merchant
    Mayo Clinic Proceedings.2016; 91(10): 1372.     CrossRef
  • Waist Circumference as a Marker of Obesity Is More Predictive of Coronary Artery Calcification than Body Mass Index in Apparently Healthy Korean Adults: The Kangbuk Samsung Health Study
    Jongsin Park, Eun Seo Lee, Da Young Lee, Jihyun Kim, Se Eun Park, Cheol-Young Park, Won-Young Lee, Ki-Won Oh, Sung-Woo Park, Eun-Jung Rhee
    Endocrinology and Metabolism.2016; 31(4): 559.     CrossRef

Diabetes Metab J : Diabetes & Metabolism Journal