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Consequences of Obesity on the Sense of Taste: Taste Buds as Treatment Targets?
Kerstin Rohde, Imke Schamarek, Matthias Blüher
Diabetes Metab J. 2020;44(4):509-528.   Published online May 11, 2020
DOI: https://doi.org/10.4093/dmj.2020.0058
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  • 39 Crossref
AbstractAbstract PDFPubReader   ePub   

Premature obesity-related mortality is caused by cardiovascular and pulmonary diseases, type 2 diabetes mellitus, physical disabilities, osteoarthritis, and certain types of cancer. Obesity is caused by a positive energy balance due to hyper-caloric nutrition, low physical activity, and energy expenditure. Overeating is partially driven by impaired homeostatic feedback of the peripheral energy status in obesity. However, food with its different qualities is a key driver for the reward driven hedonic feeding with tremendous consequences on calorie consumption. In addition to visual and olfactory cues, taste buds of the oral cavity process the earliest signals which affect the regulation of food intake, appetite and satiety. Therefore, taste buds may play a crucial role how food related signals are transmitted to the brain, particularly in priming the body for digestion during the cephalic phase. Indeed, obesity development is associated with a significant reduction in taste buds. Impaired taste bud sensitivity may play a causal role in the pathophysiology of obesity in children and adolescents. In addition, genetic variation in taste receptors has been linked to body weight regulation. This review discusses the importance of taste buds as contributing factors in the development of obesity and how obesity may affect the sense of taste, alterations in food preferences and eating behavior.

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    Physiology & Behavior.2024; 275: 114446.     CrossRef
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    Current Oral Health Reports.2024; 11(4): 283.     CrossRef
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    Nutrients.2024; 16(16): 2633.     CrossRef
  • Relationships between sensory processing patterns and metabolic risk factors among community dwelling people with metabolic syndrome: A cross-sectional and correlational research design
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    PLOS ONE.2024; 19(9): e0308421.     CrossRef
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    Eating Behaviors.2023; 48: 101698.     CrossRef
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    Nutrients.2023; 15(5): 1114.     CrossRef
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    Nutrients.2023; 15(5): 1281.     CrossRef
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    Acta Physiologica.2023;[Epub]     CrossRef
  • The role of the oral microbiome in obesity and metabolic disease: potential systemic implications and effects on taste perception
    Imke Schamarek, Lars Anders, Rima M. Chakaroun, Peter Kovacs, Kerstin Rohde-Zimmermann
    Nutrition Journal.2023;[Epub]     CrossRef
  • Smell, taste and food habits changes along body mass index increase: an observational study
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    European Archives of Oto-Rhino-Laryngology.2023; 280(12): 5595.     CrossRef
  • Sweet-inhibiting effects of gurmarin on intake during repeated acute and long-term sugar exposure: A behavioural analysis using an animal model
    Raquel Rayo-Morales, Antonio Segura-Carretero, Nicolas Poirier, Loïc Briand, David Garcia-Burgos
    Journal of Functional Foods.2023; 108: 105743.     CrossRef
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    Heliyon.2023; 9(10): e19733.     CrossRef
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    Archives of Physiology and Biochemistry.2023; : 1.     CrossRef
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    Nutrients.2022; 14(3): 555.     CrossRef
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    Nutrients.2022; 14(4): 866.     CrossRef
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    Journal of Oral Rehabilitation.2022; 49(5): 529.     CrossRef
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    Nutrients.2022; 14(6): 1261.     CrossRef
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    Bioscience, Biotechnology, and Biochemistry.2022; 86(5): 655.     CrossRef
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    Journal of Clinical Medicine.2022; 11(14): 3957.     CrossRef
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    Obesity Reviews.2022;[Epub]     CrossRef
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    Current Opinion in Physiology.2021; 20: 57.     CrossRef
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    Childhood Obesity.2021; 17(2): 136.     CrossRef
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    Clinical Nutrition.2021; 40(5): 2707.     CrossRef
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