Skip Navigation
Skip to contents

Diabetes Metab J : Diabetes & Metabolism Journal

Search
OPEN ACCESS

Search

Page Path
HOME > Search
4 "Dong-Lim Kim"
Filter
Filter
Article category
Keywords
Publication year
Authors
Original Article
Clinical Care/Education
Is an Oral Glucose Tolerance Test Still Valid for Diagnosing Diabetes Mellitus?
Dong-Lim Kim, Sun-Doo Kim, Suk Kyeong Kim, Sooyoun Park, Kee-Ho Song
Diabetes Metab J. 2016;40(2):118-128.   Published online November 20, 2015
DOI: https://doi.org/10.4093/dmj.2016.40.2.118
  • 4,881 View
  • 68 Download
  • 18 Web of Science
  • 16 Crossref
AbstractAbstract PDFPubReader   
Background

We evaluated the diagnostic rate of diabetes using fasting plasma glucose (FPG), 2-hour plasma glucose (2h PG) after 75 g oral glucose tolerance test (OGTT), and glycosylated hemoglobin (HbA1c) levels, and we elucidated the pathophysiologic characteristics and risk factors that give rise to diabetes in patients with prediabetes.

Methods

The data of 236 patients who had the OGTT at Konkuk University Hospital were analyzed. Fasting, 30, and 120 minutes blood glucose levels and insulin levels were measured. The diagnostic rate of diabetes was assessed using FPG, 2h PG, and HbA1c levels. The clinical data and insulin resistance and secretion evaluations were compared using indexes according to the fasting glucose level.

Results

Among 236 subjects, 97 (41.1%) were diabetics and 102 (43.2%) were prediabetics. The rate of diabetes diagnosis by one of the individual criteria was 56.7%, 53.6%, and 84.5% for FPG, HbA1c, and 2h PG, respectively. When two criteria were used to diagnose diabetes, 72.2% of the diabetic patients were identified by FPG and HbA1c, while 100% were identified by FPG and 2h PG, and 91.7% were identified by 2h PG and HbA1c. The HbA1c cut-off value for 2h PG ≥200 mg/dL was 6.1%, and the FPG cut-off value was 115 mg/dL. In impaired fasting glucose subjects, the HbA1c level, Matsuda index, and insulinogenic index were associated with risk of occurrence of overt diabetes (P<0.01).

Conclusion

This study suggests that performing additional OGTT for patients with FPG ≥110 mg/dL or HbA1c ≥6.1% is helpful to reclassify their glucose tolerance status and evaluate their potential for progressing to overt diabetes.

Citations

Citations to this article as recorded by  
  • The effect of preprandial versus postprandial physical activity on glycaemia: Meta-analysis of human intervention studies
    Romy Slebe, Eva Wenker, Linda J. Schoonmade, Emma J. Bouman, Denis P. Blondin, David J.T. Campbell, André C. Carpentier, Joris Hoeks, Parminder Raina, Patrick Schrauwen, Mireille J. Serlie, Dirk Jan Stenvers, Renée de Mutsert, Joline W.J. Beulens, Femke R
    Diabetes Research and Clinical Practice.2024; 210: 111638.     CrossRef
  • Dysglycaemia prediction using readily available clinical, anthropometric, and biochemical measurements
    R. Guizar-Heredia, M. Guevara-Cruz, M. Aguilar-López, L.E. González-Salazar, I. Medina-Vera, L. Arteaga-Sánchez, E. Pichardo-Ontiveros, A.E. Serralde-Zúñiga, A. Diaz-Villaseñor, A. Ávila-Nava, N. Torres, A.R. Tovar
    Clinical Nutrition Open Science.2024; 55: 91.     CrossRef
  • Dichotomy in the Impact of Elevated Maternal Glucose Levels on Neonatal Epigenome
    Ives Yubin Lim, Xinyi Lin, Ai Ling Teh, Yonghui Wu, Li Chen, Menglan He, Shiao-Yng Chan, Julia L MacIsaac, Jerry K Y Chan, Kok Hian Tan, Mary Foong Fong Chong, Michael S Kobor, Keith M Godfrey, Michael J Meaney, Yung Seng Lee, Johan G Eriksson, Peter D Gl
    The Journal of Clinical Endocrinology & Metabolism.2022; 107(3): e1277.     CrossRef
  • Imaging evaluation of the pancreas in diabetic patients
    Ni Zeng, Yi Wang, Yue Cheng, Zixing Huang, Bin Song
    Abdominal Radiology.2022; 47(2): 715.     CrossRef
  • The Impact of Financial Incentives on Behavior and Self-Management of Uncontrolled Type 2 Diabetes: Pre- and Post-Quasiexperimental Study
    Dalal Abdulaziz Al Kathiry, Fatima Al Slail, Khaled Al-Surimi, Raghib Abusaris
    Global Journal on Quality and Safety in Healthcare.2021; 4(3): 88.     CrossRef
  • Practice Patterns in the Acceptance of Medically Complex Living Kidney Donors with Obesity, Hypertension, Family History of Kidney Disease, or Donor-Recipient Age Discrepancy
    Ziad Arabi, Muhammad Bukhari, Abdullah Hamad, Abdulrahman Altheaby, Saleh Kaysi
    Avicenna Journal of Medicine.2021; 11(04): 172.     CrossRef
  • Secretagogin is Related to Insulin Secretion but Unrelated to Gestational Diabetes Mellitus Status in Pregnancy
    Carola Deischinger, Jürgen Harreiter, Karoline Leitner, Dagmar Bancher-Todesca, Sabina Baumgartner-Parzer, Alexandra Kautzky-Willer
    Journal of Clinical Medicine.2020; 9(7): 2277.     CrossRef
  • Hypoglycemic activity of extracts of Chamaecyparis obtusa var. formosana leaf in rats with hyperglycemia induced by high-fat diets and streptozotocin
    Chia-Yun Hsu, Gong-Min Lin, Shang-Tzen Chang
    Journal of Traditional and Complementary Medicine.2020; 10(4): 389.     CrossRef
  • Optimal fasting plasma glucose and haemoglobin A1c levels for screening of prediabetes and diabetes according to 2‐hour plasma glucose in a high‐risk population: The Korean Diabetes Prevention Study
    Seon‐Ah Cha, Suk Chon, Jae‐Seung Yun, Sang Youl Rhee, Sun‐Young Lim, Kun‐Ho Yoon, Yu‐Bae Ahn, Seung‐Hyun Ko, Jeong‐Taek Woo, Jin‐Hee Lee
    Diabetes/Metabolism Research and Reviews.2020;[Epub]     CrossRef
  • Prediction of type 2 diabetes mellitus using fasting plasma glucose and HbA1c levels among individuals with impaired fasting plasma glucose: a cross-sectional study in Thailand
    Tullaya Sitasuwan, Raweewan Lertwattanarak
    BMJ Open.2020; 10(11): e041269.     CrossRef
  • The effect of oral glucose tolerance testing on changes in arterial stiffness and blood pressure in elderly women with hypertension and relationships between the stage of diabetes and physical fitness levels
    Jaesong Lee, Wonil Park, Eunsook Sung, Bokbeom Kim, Nahyun Kim, Saejong Park, Chulho Shin, Jonghoon Park
    Physical Activity and Nutrition.2020; 24(4): 34.     CrossRef
  • From Pre-Diabetes to Diabetes: Diagnosis, Treatments and Translational Research
    Radia Khan, Zoey Chua, Jia Tan, Yingying Yang, Zehuan Liao, Yan Zhao
    Medicina.2019; 55(9): 546.     CrossRef
  • Molecular imaging of β-cells: diabetes and beyond
    Weijun Wei, Emily B. Ehlerding, Xiaoli Lan, Quan-Yong Luo, Weibo Cai
    Advanced Drug Delivery Reviews.2019; 139: 16.     CrossRef
  • HbA1c Cutoff for Prediabetes and Diabetes Based on Oral Glucose Tolerance Test in Obese Children and Adolescents
    Hyo-Kyoung Nam, Won Kyoung Cho, Jae Hyun Kim, Young-Jun Rhie, Sochung Chung, Kee-Hyoung Lee, Byung-Kyu Suh
    Journal of Korean Medical Science.2018;[Epub]     CrossRef
  • Detection of glucose metabolism disorders in coronary patients enrolled in cardiac rehabilitation: Is glycated haemoglobin useful? Data from the prospective REHABDIAB study
    Sopio Tatulashvili, Bénédicte Patois-Vergès, Amandine Nguyen, Marie-Cécile Blonde, Bruno Vergès
    European Journal of Preventive Cardiology.2018; 25(5): 464.     CrossRef
  • Imaging in pancreatic disease
    Julien Dimastromatteo, Teresa Brentnall, Kimberly A. Kelly
    Nature Reviews Gastroenterology & Hepatology.2017; 14(2): 97.     CrossRef
Editorials
Metformin Based Dual-Combination Therapies in Drug Naïve Type 2 Diabetic Patients
Dong-Lim Kim
Diabetes Metab J. 2013;37(6):429-432.   Published online December 12, 2013
DOI: https://doi.org/10.4093/dmj.2013.37.6.429
  • 2,998 View
  • 30 Download
  • 3 Crossref
PDFPubReader   

Citations

Citations to this article as recorded by  
  • Association between Metformin Use and Risk of Lactic Acidosis or Elevated Lactate Concentration in Type 2 Diabetes
    Eun Young Lee, Sena Hwang, Yong-ho Lee, Seo Hee Lee, Young Mi Lee, Hua Pyong Kang, Eugene Han, Woonhyoung Lee, Byung-Wan Lee, Eun Seok Kang, Bong Soo Cha, Hyun Chul Lee
    Yonsei Medical Journal.2017; 58(2): 312.     CrossRef
  • Initial Combination Therapy With Canagliflozin Plus Metformin Versus Each Component as Monotherapy for Drug-Naïve Type 2 Diabetes
    Julio Rosenstock, Leonard Chuck, Manuel González-Ortiz, Kate Merton, Jagriti Craig, George Capuano, Rong Qiu
    Diabetes Care.2016; 39(3): 353.     CrossRef
  • Cardioprotective effect of concomitant administration of trigonelline and sitagliptin on cardiac biomarkers, lipid levels, electrocardiographic and heamodynamic modulation on cardiomyopathy in diabetic Wistar rats
    Hemant V. Kamble, Subhash L. Bodhankar
    Biomedicine & Aging Pathology.2014; 4(4): 335.     CrossRef
Candidate Dipeptidyl Peptidase-4 Inhibitors for the Treatment of Type 2 Diabetes
Yun-Mi Jang, Dong-Lim Kim
Diabetes Metab J. 2011;35(2):117-118.   Published online April 30, 2011
DOI: https://doi.org/10.4093/dmj.2011.35.2.117
  • 2,544 View
  • 24 Download
PDFPubReader   
Letter

Diabetes Metab J : Diabetes & Metabolism Journal