Diabetes & Metabolism Journal

Original Articles

Clinical Diabetes & Therapeutics
Efficacy and Safety of Voglibose Plus Metformin in Patients with Type 2 Diabetes Mellitus: A Randomized Controlled Trial: Tae Jung Oh, Jae Myung Yu, Kyung Wan Min, Hyun Shik Son, Moon Kyu Lee, Kun Ho Yoon, Young Duk Song, Joong Yeol Park, In Kyung Jeong, Bong Soo Cha, Yong Seong Kim, Sei Hyun Baik, In Joo Kim, Doo Man Kim, Sung Rae Kim, Kwan Woo Lee, Jeong Hyung Park, In Kyu Lee, Tae Sun Park, Sung Hee Choi, Sung Woo Park; Diabetes Metab J. 2019;43(3):276-286. Published online December 7, 2018; DOI: https://doi.org/10.4093/dmj.2018.0051

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Background

Combination of metformin to reduce the fasting plasma glucose level and an α-glucosidase inhibitor to decrease the postprandial glucose level is expected to generate a complementary effect. We compared the efficacy and safety of a fixed-dose combination of voglibose plus metformin (vogmet) with metformin monotherapy in drug-naïve newly-diagnosed type 2 diabetes mellitus.

Methods

A total of 187 eligible patients aged 20 to 70 years, with a glycosylated hemoglobin (HbA1c) level of 7.0% to 11.0%, were randomized into either vogmet or metformin treatments for 24 weeks. A change in the HbA1c level from baseline was measured at week 24.

Results

The reduction in the levels of HbA1c was −1.62%±0.07% in the vogmet group and −1.31%±0.07% in the metformin group (P=0.003), and significantly more vogmet-treated patients achieved the target HbA1c levels of <6.5% (P=0.002) or <7% (P=0.039). Glycemic variability was also significantly improved with vogmet treatment, estimated by M-values (P=0.004). Gastrointestinal adverse events and hypoglycemia (%) were numerically lower in the vogmet-treated group. Moreover, a significant weight loss was observed with vogmet treatment compared with metformin (−1.63 kg vs. −0.86 kg, P=0.039).

Conclusion

Vogmet is a safe antihyperglycemic agent that controls blood glucose level effectively, yields weight loss, and is superior to metformin in terms of various key glycemic parameters without increasing the risk of hypoglycemia.

Citations

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Phytochemical analysis and antihyperglycemic activity of Castilleja arvensis
Mónica Aideé Díaz-Román, Juan José Acevedo-Fernández, Gabriela Ávila-Villarreal, Elizabeth Negrete-León, A. Berenice Aguilar-Guadarrama
Fitoterapia.2024; 174: 105839. CrossRef
Efficacy and Safety of DPP-4 Inhibitors and Metformin Combinations in Type 2 Diabetes: A Systematic Literature Review and Network Meta-Analysis
Rongping Chen, Jing Li, Danqi Chen, Weiheng Wen, Susu Zhang, Jitong Li, Yuting Ruan, Zhen Zhang, Jia Sun, Hong Chen
Diabetes, Metabolic Syndrome and Obesity.2024; Volume 17: 2471. CrossRef
Metformin-Associated Gastrointestinal Adverse Events Are Reduced by Probiotics: A Meta-Analysis
Izabela Szymczak-Pajor, Józef Drzewoski, Sylwia Wenclewska, Agnieszka Śliwińska
Pharmaceuticals.2024; 17(7): 898. CrossRef
YAP/TAZ axis was involved in the effects of metformin on breast cancer
Yu Xu, Hongke Cai, Yuanfeng Xiong, Li Tang, Longjiang Li, Li Zhang, Yi Shen, Yongqiang Yang, Ling Lin, Jiayi Huang
Journal of Chemotherapy.2023; 35(7): 627. CrossRef
Diabetes Remission
Ashok Kumar, Shubha Laxmi Margekar, Ravi Kumar
Indian Journal of Medical Specialities.2023; 14(1): 3. CrossRef
Analysis of Reports Sent to the Portuguese Pharmacovigilance System and Published Literature Regarding the Safety of Metformin in the Elderly
Beatriz Esteves, Cristina Monteiro, Ana Paula Coelho Duarte
Healthcare.2023; 11(15): 2197. CrossRef
Rapid prediction method of α-Glycosidase inhibitory activity of Coreopsis tinctoria extract from different habitats by near infrared spectroscopy
Xiaogang He, Xiang Han, Jiaping Yu, Yulong Feng, Ganghui Chu
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy.2022; 268: 120601. CrossRef
Insulin autoimmune syndrome in patients with type 2 diabetes: A report of two cases
Y. Shin, T.J. Oh, S.H. Choi, H.C. Jang
Diabetes & Metabolism.2021; 47(1): 101115. CrossRef
Efficacy and Safety of Treatment with Quadruple Oral Hypoglycemic Agents in Uncontrolled Type 2 Diabetes Mellitus: A Multi-Center, Retrospective, Observational Study
Jun Sung Moon, Sunghwan Suh, Sang Soo Kim, Heung Yong Jin, Jeong Mi Kim, Min Hee Jang, Kyung Ae Lee, Ju Hyung Lee, Seung Min Chung, Young Sang Lyu, Jin Hwa Kim, Sang Yong Kim, Jung Eun Jang, Tae Nyun Kim, Sung Woo Kim, Eonju Jeon, Nan Hee Cho, Mi-Kyung Ki
Diabetes & Metabolism Journal.2021; 45(5): 675. CrossRef
Quantifying Remission Probability in Type 2 Diabetes Mellitus
Sanjay Kalra, Ganapathi Bantwal, Nitin Kapoor, Rakesh Sahay, Saptarshi Bhattacharya, Beatrice Anne, Raju A Gopal, Sunil Kota, Ashok Kumar, Ameya Joshi, Debmalya Sanyal, Mangesh Tiwaskar, Ashok Kumar Das
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The effect of voglibose on metabolic profiles in patients with type 2 diabetes mellitus: A systematic review and meta-analysis of clinical trials
Peyman Nowrouzi-Sohrabi, Reza Tabrizi, Shahla Rezaei, Fatemeh Jafari, Kamran Hessami, Mehdi Abedi, Mohammad Jalali, Pedram Keshavarzi, Saeed Shahabi, Ali Asghar Kolahi, Kristin Carson-Chahhoud, Amirhossein Sahebkar, Saeid Safiri
Pharmacological Research.2020; 159: 104988. CrossRef
Role of Intestinal Microbiota in Metabolism of Voglibose In Vitro and In Vivo
Mahesh Raj Nepal, Mi Jeong Kang, Geon Ho Kim, Dong Ho Cha, Ju-Hyun Kim, Tae Cheon Jeong
Diabetes & Metabolism Journal.2020; 44(6): 908. CrossRef
Response: Efficacy and Safety of Voglibose Plus Metformin in Patients with Type 2 Diabetes Mellitus: A Randomized Controlled Trial (Diabetes metab J 2019;43;276-86)
Tae Jung Oh, Sung Hee Choi
Diabetes & Metabolism Journal.2019; 43(4): 547. CrossRef
Letter: Efficacy and Safety of Voglibose Plus Metformin in Patients with Type 2 Diabetes Mellitus: A Randomized Controlled Trial (Diabetes Metab J 2019;43;276-86)
Hannah Seok, Tae Seo Sohn
Diabetes & Metabolism Journal.2019; 43(4): 545. CrossRef

1,5-Anhydroglucitol as a Useful Marker for Assessing Short-Term Glycemic Excursions in Type 1 Diabetes: Hannah Seok, Ji Hye Huh, Hyun Min Kim, Byung-Wan Lee, Eun Seok Kang, Hyun Chul Lee, Bong Soo Cha; Diabetes Metab J. 2015;39(2):164-170. Published online March 9, 2015; DOI: https://doi.org/10.4093/dmj.2015.39.2.164

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Background

Type 1 diabetes is associated with more severe glycemic variability and more frequent hypoglycemia than type 2 diabetes. Glycemic variability is associated with poor glycemic control and diabetic complications. In this study, we demonstrate the clinical usefulness of serum 1,5-anhydroglucitol (1,5-AG) for assessing changes in glycemic excursion in type 1 diabetes.

Methods

Seventeen patients with type 1 diabetes were enrolled in this study. A continuous glucose monitoring system (CGMS) was applied twice at a 2-week interval to evaluate changes in glycemic variability. The changes in serum glycemic assays, including 1,5-AG, glycated albumin and hemoglobin A1c (HbA1c), were also evaluated.

Results

Most subjects showed severe glycemic excursions, including hypoglycemia and hyperglycemia. The change in 1,5-AG level was significantly correlated with changes in the glycemic excursion indices of the standard deviation (SD), mean amplitude of glucose excursion (MAGE), lability index, mean postmeal maximum glucose, and area under the curve for glucose above 180 mg/dL (r=-0.576, -0.613, -0.600, -0.630, and -0.500, respectively; all P<0.05). Changes in glycated albumin were correlated with changes in SD and MAGE (r=0.495 and 0.517, respectively; all P<0.05). However, changes in HbA1c were not correlated with any changes in the CGMS variables.

Conclusion

1,5-AG may be a useful marker for the assessment of short-term changes in glycemic variability. Furthermore, 1,5-AG may have clinical implications for the evaluation and treatment of glycemic excursions in type 1 diabetes.

Citations

Citations to this article as recorded by

The progress of clinical research on the detection of 1,5-anhydroglucitol in diabetes and its complications
Huijuan Xu, Junhua Pan, Qiu Chen
Frontiers in Endocrinology.2024;[Epub] CrossRef
Glycation and Glucose Variability in Subjects with Type 1 Diabetes
V. V. Klimontov, D. M. Bulumbaeva, J. F. Semenova
Biochemistry (Moscow), Supplement Series B: Biomedical Chemistry.2024; 18(1): 59. CrossRef
Glycemic dispersion: a new index for screening high glycemic variability
Rui Shi, Lei Feng, Yan-Mei Liu, Wen-Bo Xu, Bei-Bei Luo, Ling-Tong Tang, Qian-Ye Bi, Hui-Ying Cao
Diabetology & Metabolic Syndrome.2023;[Epub] CrossRef
Digital Behavior Change Interventions to Reduce Sedentary Behavior and Promote Physical Activity in Adults with Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Xiaoyan Zhang, Xue Qiao, Ke Peng, Shan Gao, Yufang Hao
International Journal of Behavioral Medicine.2023;[Epub] CrossRef
DBS are suitable for 1,5-anhydroglucitol monitoring in GSD1b and G6PC3-deficient patients taking SGLT2 inhibitors to treat neutropenia
Joseph P. Dewulf, Nathalie Chevalier, Sandrine Marie, Maria Veiga-da-Cunha
Molecular Genetics and Metabolism.2023; 140(3): 107712. CrossRef
The correlation between serum 1, 5-anhydroglucitol and β-cell function in Chinese adults with different glucose metabolism statuses
Yuexing Yuan, Yuanyuan Tan, Yao Wang, Shanhu Qiu, Jiao Yang, Cheng Chen
International Journal of Diabetes in Developing Countries.2023;[Epub] CrossRef
HbA1c combined with glycated albumin or 1,5‐anhydroglucitol improves the efficiency of diabetes screening in a Chinese population
Junyi Qian, Cheng Chen, Xiaohang Wang, Yuanyuan Tan, Jiao Yang, Yuexing Yuan, Juan Chen, Haijian Guo, Bei Wang, Zilin Sun, Yao Wang
Diabetic Medicine.2022;[Epub] CrossRef
Assessment of glycemia in chronic kidney disease
Mohamed Hassanein, Tariq Shafi
BMC Medicine.2022;[Epub] CrossRef
Continuous subcutaneous insulin infusion alters microRNA expression and glycaemic variability in children with type 1 diabetes
Emma S. Scott, Andrzej S. Januszewski, Luke M. Carroll, Gregory R. Fulcher, Mugdha V. Joglekar, Anandwardhan A. Hardikar, Timothy W. Jones, Elizabeth A. Davis, Alicia J. Jenkins
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Red rice koji extract alleviates hyperglycemia by increasing glucose uptake and glucose transporter type 4 levels in skeletal muscle in two diabetic mouse models
Takakazu Yagi, Koji Ataka, Kai-Chun Cheng, Hajime Suzuki, Keizaburo Ogata, Yumiko Yoshizaki, Kazunori Takamine, Ikuo Kato, Shouichi Miyawaki, Akio Inui, Akihiro Asakawa
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How tightly controlled do fluctuations in blood glucose levels need to be to reduce the risk of developing complications in people with Type 1 diabetes?
R. Livingstone, J. G. Boyle, J. R. Petrie
Diabetic Medicine.2020; 37(4): 513. CrossRef
Resolution on the results of the first working meeting of the scientific advisory board «Actual problems of glycemic variability as a new criterion of glycemic control and safety of diabetes therapy»
Mikhail B. Antsiferov, Gagik R. Galstyan, Alexey V. Zilov, Alexander Y. Mayorov, Tatyana N. Markova, Nikolay A. Demidov, Olga M. Koteshkova, Dmitry N. Laptev, Alisa V. Vitebskaya
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Hyperglycemia and Carotenoid Intake Are Associated with Serum Carotenoids in Youth with Type 1 Diabetes
Namrata Sanjeevi, Leah M. Lipsky, Tonja R. Nansel
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Correlation of Serum 1,5-AG with Uric Acid in Type 2 Diabetes Mellitus with Different Renal Functions
Kai Zhang, Bizhen Xue, Yuexing Yuan, Yao Wang
International Journal of Endocrinology.2019; 2019: 1. CrossRef
Glycaemic control and glycaemic variability in older people with diabetes
Hermes J Florez
The Lancet Diabetes & Endocrinology.2018; 6(6): 433. CrossRef
Alternate glycemic markers reflect glycemic variability in continuous glucose monitoring in youth with prediabetes and type 2 diabetes
Christine L. Chan, Laura Pyle, Megan M. Kelsey, Lindsey Newnes, Amy Baumgartner, Philip S. Zeitler, Kristen J. Nadeau
Pediatric Diabetes.2017; 18(7): 629. CrossRef
1,5-anidroglucitolo: un marcatore non tradizionale di iperglicemia
Gabriella Lavalle, Roberto Testa, Maria Elisabetta Onori, Raffaella Vero, Anna Vero
La Rivista Italiana della Medicina di Laboratorio - Italian Journal of Laboratory Medicine.2017; 13(3-4): 139. CrossRef
Glycemic control and variability in association with body mass index and body composition over 18months in youth with type 1 diabetes
Leah M. Lipsky, Benjamin Gee, Aiyi Liu, Tonja R. Nansel
Diabetes Research and Clinical Practice.2016; 120: 97. CrossRef
How Can We Easily Measure Glycemic Variability in Diabetes Mellitus?
Suk Chon
Diabetes & Metabolism Journal.2015; 39(2): 114. CrossRef
Alternative biomarkers for assessing glycemic control in diabetes: fructosamine, glycated albumin, and 1,5-anhydroglucitol
Ji-Eun Lee
Annals of Pediatric Endocrinology & Metabolism.2015; 20(2): 74. CrossRef
Glycemic Variability: How Do We Measure It and Why Is It Important?
Sunghwan Suh, Jae Hyeon Kim
Diabetes & Metabolism Journal.2015; 39(4): 273. CrossRef

The Glycated Albumin to Glycated Hemoglobin Ratio Might Not Be Associated with Carotid Atherosclerosis in Patients with Type 1 Diabetes: Wonjin Kim, Kwang Joon Kim, Byung-Wan Lee, Eun Seok Kang, Bong Soo Cha, Hyun Chul Lee; Diabetes Metab J. 2014;38(6):456-463. Published online December 15, 2014; DOI: https://doi.org/10.4093/dmj.2014.38.6.456

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Background

The ratio of glycated albumin to glycated hemoglobin (GA/A1c) is known to be elevated in subjects with type 2 diabetes mellitus (T2DM) who had decreased insulin secretion. Additionally, the carotid intima media thickness (IMT) is greater in T2DM patients with higher GA/A1c ratios. We investigated whether increased GA/A1c ratio and IMT are also associated in type 1 diabetes mellitus (T1DM), which is characterized by lack of insulin secretory capacity.

Methods

In this cross-sectional study, we recruited 81 T1DM patients (33 men, 48 women; mean age 44.1±13.0 years) who underwent carotid IMT, GA, and HbA1c measurements.

Results

The mean GA/A1c ratio was 2.90. Based on these results, we classified the subjects into two groups: group I (GA/A1c ratio <2.90, n=36) and group II (GA/A1c ratio ≥2.90, n=45). Compared with group I, the body mass indexes (BMIs), waist circumferences, and IMTs were lower in group II. GA/A1c ratio was negatively correlated with BMI, urine albumin to creatinine ratio (P<0.001 for both), and both the mean and maximal IMT (P=0.001, both). However, after adjusting the confounding factors, we observed that IMT was no longer associated with GA/A1c ratio.

Conclusion

In contrast to T2DM, IMT was not significantly related to GA/A1c ratio in the subjects with T1DM. This suggests that the correlations between GA/A1c ratio and the parameters known to be associated with atherosclerosis in T2DM could be manifested differently in T1DM. Further studies are needed to investigate these relationships in T1DM.

Citations

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High glycated albumin is associated with early neurological deterioration in patients with acute ischemic stroke
Ki-Woong Nam, Jung Hoon Han, Chi Kyung Kim, Hyung-Min Kwon, Yong-Seok Lee, Kyungmi Oh, Keon-Joo Lee, Byeongsu Park
BMC Neurology.2024;[Epub] CrossRef
Glycated Albumin and Glycated Albumin/HbA1c Predict the Progression of Coronavirus Disease 2019 from Mild to Severe Disease in Korean Patients with Type 2 Diabetes
Jeongseon Yoo, Youngah Choi, Shin Ae Park, Ji Yeon Seo, Chul Woo Ahn, Jaehyun Han
Journal of Clinical Medicine.2022; 11(9): 2327. CrossRef
Variability in glycated albumin levels predicts the progression of diabetic nephropathy
Su Bin Park, Sang Soo Kim, In Joo Kim, Yoon Jeong Nam, Kang Hee Ahn, Jong Ho Kim, Yun Kyung Jeon, Bo Hyun Kim, Sang Heon Song, Ihm Soo Kwak, Eun Kyung Lee, Yong Ki Kim
Journal of Diabetes and its Complications.2017; 31(6): 1041. CrossRef
Significant liver fibrosis assessed using liver transient elastography is independently associated with low bone mineral density in patients with non-alcoholic fatty liver disease
Gyuri Kim, Kwang Joon Kim, Yumie Rhee, Sung-Kil Lim, Salvatore Petta
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Determinants of Preclinical Atherosclerosis Are Different in Type 1 and Type 2 Diabetic Women
P. PIŤHOVÁ, K. ŠTECHOVÁ, J. PIŤHA, V. LÁNSKÁ, M. KVAPIL
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Gyuri Kim, Yong-ho Lee, Eun Seok Kang, Bong-Soo Cha, Hyun Chul Lee, Byung-Wan Lee
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Visceral adiposity is associated with altered myocardial glucose uptake measured by 18FDG-PET in 346 subjects with normal glucose tolerance, prediabetes, and type 2 diabetes
Gyuri Kim, Kwanhyeong Jo, Kwang Joon Kim, Yong-ho Lee, Eugene Han, Hye-jin Yoon, Hye Jin Wang, Eun Seok Kang, Mijin Yun
Cardiovascular Diabetology.2015;[Epub] CrossRef
Glycated albumin and the risk of micro- and macrovascular complications in subjects with Type 1 Diabetes
Hye-jin Yoon, Yong-ho Lee, So Ra Kim, Tyler Hyungtaek Rim, Eun Young Lee, Eun Seok Kang, Bong-Soo Cha, Hyun Chul Lee, Byung-Wan Lee
Cardiovascular Diabetology.2015;[Epub] CrossRef
Comparison of Candidate Pairs of Hydrolytic Enzymes for Spectrophotometric-dual-enzyme-simultaneous-assay
Hongbo Liu, Mei Yuan, Xiaolan Yang, Xiaolei Hu, Juan Liao, Jizheng Dang, Yanling Xie, Jun Pu, Yuanli Li, Chang-Guo Zhan, Fei Liao
Analytical Sciences.2015; 31(5): 421. CrossRef
Glycated Albumin Levels in Patients with Type 2 Diabetes Increase Relative to HbA1cwith Time
Hye-jin Yoon, Yong-ho Lee, Kwang Joon Kim, So Ra Kim, Eun Seok Kang, Bong-Soo Cha, Hyun Chul Lee, Byung-Wan Lee
BioMed Research International.2015; 2015: 1. CrossRef
Association of hemoglobin A1c and glycated albumin with carotid atherosclerosis in community-dwelling Japanese subjects: the Hisayama Study
Naoko Mukai, Toshiharu Ninomiya, Jun Hata, Yoichiro Hirakawa, Fumie Ikeda, Masayo Fukuhara, Taeko Hotta, Masafumi Koga, Udai Nakamura, Dongchon Kang, Takanari Kitazono, Yutaka Kiyohara
Cardiovascular Diabetology.2015;[Epub] CrossRef

Background and Data Configuration Process of a Nationwide Population-Based Study Using the Korean National Health Insurance System: Sun Ok Song, Chang Hee Jung, Young Duk Song, Cheol-Young Park, Hyuk-Sang Kwon, Bong Soo Cha, Joong-Yeol Park, Ki-Up Lee, Kyung Soo Ko, Byung-Wan Lee; Diabetes Metab J. 2014;38(5):395-403. Published online October 17, 2014; DOI: https://doi.org/10.4093/dmj.2014.38.5.395

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Background

The National Health Insurance Service (NHIS) recently signed an agreement to provide limited open access to the databases within the Korean Diabetes Association for the benefit of Korean subjects with diabetes. Here, we present the history, structure, contents, and way to use data procurement in the Korean National Health Insurance (NHI) system for the benefit of Korean researchers.

Methods

The NHIS in Korea is a single-payer program and is mandatory for all residents in Korea. The three main healthcare programs of the NHI, Medical Aid, and long-term care insurance (LTCI) provide 100% coverage for the Korean population. The NHIS in Korea has adopted a fee-for-service system to pay health providers. Researchers can obtain health information from the four databases of the insured that contain data on health insurance claims, health check-ups and LTCI.

Results

Metabolic disease as chronic disease is increasing with aging society. NHIS data is based on mandatory, serial population data, so, this might show the time course of disease and predict some disease progress, and also be used in primary and secondary prevention of disease after data mining.

Conclusion

The NHIS database represents the entire Korean population and can be used as a population-based database. The integrated information technology of the NHIS database makes it a world-leading population-based epidemiology and disease research platform.

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Proton Pump Inhibitor for Gastrointestinal Bleeding in Patients with Myocardial Infarction on Dual-Antiplatelet Therapy: A Nationwide Cohort Study
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Cancer Incidence Among Residents Near Coal-Fired Power Plants Based on the Korean National Health Insurance System Data
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Risk of avascular necrosis in patients with inflammatory bowel disease: Insights from a nationwide cohort study and the impact of corticosteroid use
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Liver Cancer Risk Across Metabolic Dysfunction-Associated Steatotic Liver Disease and/or Alcohol: A Nationwide Study
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Fenofibrate’s impact on cardiovascular risk in patients with diabetes: a nationwide propensity-score matched cohort study
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Nationwide analysis of EVAR explantation outcomes in Korea: A comprehensive dataset study
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Elevated Risk of Stroke in Young Adults After Traumatic Brain Injury: A Nationwide Study of 1 Million Individuals
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Journal of the American Heart Association.2024;[Epub] CrossRef
Improved Proteinuria May Attenuate the Risk of Atrial Fibrillation: A Nationwide Population-Based Cohort Study
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Estimated economic costs of dental implants among older South Korean adults, 2015–2018
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Risk of depression in amyotrophic lateral sclerosis: A nationwide cohort study in South Korea
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Association Between Influenza Vaccination and Acute Kidney Injury Among the Elderly: A Self‐Controlled Case Series
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Inequality in Mortality and Cardiovascular Risk Among Young, Low-Income, Self-Employed Workers: Nationwide Retrospective Cohort Study
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Changes in seasonality and sex ratio of scrub typhus: a case study of South Korea from 2003 to 2019 based on wavelet transform analysis
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SGLT2 Inhibitor Use and Risk of Dementia and Parkinson Disease Among Patients With Type 2 Diabetes
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Metabolic Dysfunction-Associated Steatotic Liver Disease Is Associated with Increased Risk of Kidney Cancer: A Nationwide Study
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Incidence and prevalence of seropositive rheumatoid arthritis among Korean women of childbearing age: a nationwide population-based study
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The Korean Journal of Internal Medicine.2023; 38(1): 125. CrossRef
Myth and Truth in Opioid Consumption with Intrathecal Morphine Pump Implantation in Chronic Pain: A Retrospective Cohort Study with Claims Database in South Korea
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Epidemiology of idiopathic sudden sensorineural hearing loss in the era of big data
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European Archives of Oto-Rhino-Laryngology.2023; 280(5): 2181. CrossRef
Allergic Diseases and Risk of Incident Dementia and Alzheimer's Disease
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Annals of Neurology.2023; 93(2): 384. CrossRef
Post-operative recurrence of liver cancer according to antiviral therapy for detectable hepatitis B viremia: A nationwide study
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European Journal of Internal Medicine.2023; 107: 66. CrossRef
Comparable Mortality Between Asian Patients with Chronic Hepatitis B Under Long-Term Antiviral Therapy vs Matched Control: A Population-Based Study
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Body mass index, waist circumference and cardiovascular diseases in transitional ages (40 and 66 years)
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Journal of Cachexia, Sarcopenia and Muscle.2023; 14(1): 369. CrossRef
Waist circumference and end‐stage renal disease based on glycaemic status: National Health Insurance Service data 2009–2018
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Journal of Cachexia, Sarcopenia and Muscle.2023; 14(1): 585. CrossRef
Comparison of Trends in the Incidence of Traumatic Spinal Cord Injury in Daily Life, Automobile Accidents, and Industrial Accidents: A National Multi-Insurance Study in Korea
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A population-based study on the risk of prescription opioid abuse in patients with chronic opioid use and cost-effectiveness of prescription drug monitoring program using a patient simulation model in South Korea
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The effects of sociodemographic factors on help-seeking for depression: Based on the 2017–2020 Korean Community Health Survey
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Efficacy of acupuncture on cardiovascular complications in patients with diabetes mellitus in Korea: A nationwide retrospective cohort
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Journal of Integrative Medicine.2023; 21(2): 176. CrossRef
A 12-year nationwide cohort study on the association between central retinal artery occlusion and cancer
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Long-Term Nonoperative Management is Associated With Lower Mean 9-Year Follow-Up Survival Compared to Total Knee Arthroplasty in Knee Osteoarthritis Patients—Survival Analysis of a Nationwide South Korean Cohort
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The Journal of Arthroplasty.2023; 38(8): 1470. CrossRef
Positive faecal immunochemical test predicts the onset of inflammatory bowel disease: A nationwide, propensity score-matched study
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Frontiers in Immunology.2023;[Epub] CrossRef
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Association of general and central obesity, and their changes with risk of knee osteoarthritis: a nationwide population-based cohort study
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Histamine-2 Receptor Antagonists and Proton Pump Inhibitors Are Associated With Reduced Risk of SARS-CoV-2 Infection Without Comorbidities Including Diabetes, Hypertension, and Dyslipidemia: A Propensity Score-Matched Nationwide Cohort Study
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Blood pressure and dementia risk by physical frailty in the elderly: a nationwide cohort study
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Alzheimer's Research & Therapy.2023;[Epub] CrossRef
Increased risk of cardiovascular disease associated with diabetes among adult cancer survivors: a population-based matched cohort study
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European Journal of Preventive Cardiology.2023; 30(8): 670. CrossRef
Association between familial aggregation of chronic kidney disease and its incidence and progression
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Participation and Prognostic Impact of Cardiac Rehabilitation After Acute Coronary Syndrome: Big-Data Study of the Korean National Health Insurance Service
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Analysis of Anxiety or Depression and Long-term Mortality Among Survivors of Out-of-Hospital Cardiac Arrest
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Treatment Changes and Prognoses in Patients with Incident Drug-Induced Parkinsonism Using a Korean Nationwide Healthcare Claims Database
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Journal of Clinical Medicine.2023; 12(8): 2860. CrossRef
Trends in the Incidence and Etiology of Non-Traumatic Spinal Cord Injury in Korea: A Nationwide Population-Based Study From 2007 to 2020
Yoonjeong Choi, Ja-Ho Leigh, Jooeun Jeon, Goo Joo Lee, Hyung-Ik Shin, Moon Suk Bang
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The Association between Metabolic Syndrome and Epithelial Cell Abnormalities Detected on Pap Smear: A Nationwide Population-Based Study
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Journal of Clinical Medicine.2023; 12(8): 2954. CrossRef
Long‐term adverse neurodevelopmental outcomes of discordant twins delivered at term: A nationwide population‐based study
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BJOG: An International Journal of Obstetrics & Gynaecology.2023; 130(11): 1370. CrossRef
Cancer and Mortality Risks of Graves’ Disease in South Korea Based on National Data from 2010 to 2019
Young Ju Choi, Kyungdo Han, Won Kyoung Cho, Min Ho Jung, Byung-Kyu Suh
Clinical Epidemiology.2023; Volume 15: 535. CrossRef
Association of Waist Circumference with the Risk of Inflammatory Bowel Disease: a Nationwide Cohort Study of 10 Million Individuals in Korea
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Journal of Crohn's and Colitis.2023; 17(5): 681. CrossRef
Lifestyle factors and long-term survival in patients with chronic non-cancer pain: a nationwide cohort study in South Korea
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Journal of Anesthesia.2023; 37(4): 522. CrossRef
Long term renal outcome after hypertensive disease during pregnancy: a nationwide population-based study
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Lower risk of depression after smoking cessation and alcohol abstinence in patients with gastric cancer who underwent gastrectomy: A population‐based, nationwide cohort study
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Acute Pancreatitis and the Risk of Dementia in Diabetes: A Nationwide Cohort Study Using Korean Healthcare Claims Database
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Journal of Alzheimer's Disease.2023; 94(1): 205. CrossRef
Application of big data in ophthalmology
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Impact of mental disorders on the risk of heart failure among Korean patients with diabetes: a cohort study
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Evaluating Reference Ages for Selecting Prosthesis Types for Heart Valve Replacement in Korea
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JAMA Network Open.2023; 6(5): e2314671. CrossRef
Higher Non-High-Density Lipoprotein Cholesterol Was Higher Associated With Cardiovascular Disease Comparing Higher LDL-C in Nine Years Follow Up: Cohort Study
Sangmo Hong, Kyungdo Han, Jung Hwan Park, Sung Hoon Yu, Chang Beom Lee, Dong Sun Kim
Journal of Lipid and Atherosclerosis.2023; 12(2): 164. CrossRef
Impact of Allergic Disease on the Risk of Mycobacterial Disease
Taehee Kim, Hayoung Choi, Hyun Lee, Kyungdo Han, Dong Won Park, Tai Sun Park, Ji-Yong Moon, Tae-Hyung Kim, Jang Won Sohn, Ho Joo Yoon, Sang-Heon Kim
The Journal of Allergy and Clinical Immunology: In Practice.2023; 11(9): 2830. CrossRef
Trends in the Prevalence of Blindness and Correlation With Health Status in Korean Adults: A 10-Year Nationwide Population-Based Study
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Journal of Korean Medical Science.2023;[Epub] CrossRef
Association between regular physical activity and lower incidence of colorectal cancer in patients with diabetes mellitus: a nationwide cohort study
Han Hee Lee, Kyu‐na Lee, Jin Su Kim, Dae Young Cheung, Hyuk‐Sang Kwon, Bo‐In Lee, Young‐Seok Cho, Soo‐Heon Park, Kyungdo Han, Jin Il Kim
Colorectal Disease.2023; 25(8): 1588. CrossRef
Bovine pericardial versus porcine bioprosthetic mitral valves: results from a Korean Nationwide Cohort Study
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European Journal of Cardio-Thoracic Surgery.2023;[Epub] CrossRef
Examining the factors associated with inpatients’ perception of overtreatment in Korea: a cross-sectional study
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BMC Health Services Research.2023;[Epub] CrossRef
Long-term clinical outcomes of tricuspid valve replacement using bovine versus porcine valves: a nationwide population-based study
Suk Ho Sohn, Yoonjin Kang, Ji Seong Kim, Ho Young Hwang, Kyung Hwan Kim, Jae Woong Choi
European Journal of Cardio-Thoracic Surgery.2023;[Epub] CrossRef
Association of physical activity with total and cause-specific mortality in patients with diabetes: A nationwide population-based cohort study
Inha Jung, Kyung-Do Han, Sun Joon Moon, Hyemi Kwon, Se Eun Park, Eun-Jung Rhee, Won-Young Lee
Diabetes Research and Clinical Practice.2023; 202: 110819. CrossRef
The Association Between Institutional Case Volume of Hematopoietic Stem Cell Transplantation and Mortality
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Transplantation Proceedings.2023; 55(7): 1715. CrossRef
Association between periodontal disease status and risk of atrial fibrillation: a nationwide population-based cohort study
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Trends in the incidence and prevalence of dysphagia requiring medical attention among adults in South Korea, 2006–2016: A nationwide population study
SuYeon Kwon, Seungwoo Cha, Junsik Kim, Kyungdo Han, Nam-Jong Paik, Won-Seok Kim, Sina Azadnajafabad
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Socioeconomic Disparities in the Association Between All-Cause Mortality and Health Check-Up Participation Among Healthy Middle-Aged Workers: A Nationwide Study
Byungyoon Yun, Juyeon Oh, Jaesung Choi, Laura S. Rozek, Heejoo Park, Juho Sim, Yangwook Kim, Jongmin Lee, Jin-Ha Yoon
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Association between smoking status and death from COVID-19 in South Korea: A nationwide cohort study
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Tobacco Induced Diseases.2023; 21(July): 1. CrossRef
A cohort study found a high risk of end-stage kidney disease associated with acromegaly
Sangmo Hong, Kyung-Soo Kim, Kyungdo Han, Cheol-Young Park
Kidney International.2023; 104(4): 820. CrossRef
Comparative cardiovascular outcomes in type 2 diabetes patients taking dapagliflozin versus empagliflozin: a nationwide population-based cohort study
Jaehyun Lim, You-Jung Choi, Bong Sung Kim, Tae-Min Rhee, Hyun-Jung Lee, Kyung-Do Han, Jun-Bean Park, Jin Oh Na, Yong-Jin Kim, Heesun Lee, Hyung-Kwan Kim
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Effects of Statin Treatment on the Development of Tendinopathy: A Nationwide Population-Based Cohort Study
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Orthopaedic Journal of Sports Medicine.2023;[Epub] CrossRef
Incident dementia in kidney transplantation recipients: a matched comparative nationwide cohort study in South Korea
Seon Ha Baek, Jina Park, Sehoon Park, Mi-yeon Yu, Ji Eun Kim, Sang Hyun Park, Kyungdo Han, Yong Chul Kim, Dong Ki Kim, Kwon Wook Joo, Yon Su Kim, Hajeong Lee
Kidney Research and Clinical Practice.2023; 42(4): 519. CrossRef
Developing Operational Definitions Related toHelicobacter pyloriEradication Therapy
Chan Hyuk Park, Sun-Young Jung, Ju Won Lee, Hyo-Joon Yang, Joon Sung Kim, Beom Jin Kim, Soo In Choi, Seung In Seo, Joongyub Lee, Jae Gyu Kim
Journal of Korean Medical Science.2023;[Epub] CrossRef
Fracture Risk in Middle-Aged and Older Patients With Inflammatory Bowel Disease: A Korean Nationwide Population-Based Cohort Study
Ji Min Lee, Kyungdo Han, Kang-Moon Lee, Jae-Seung Yun
Journal of Korean Medical Science.2023;[Epub] CrossRef
Sex differences in mortality in patients with acromegaly: a nationwide cohort study in Korea
Jiwon Kim, Namki Hong, Jimi Choi, Ju Hyung Moon, Eui Hyun Kim, Jae Won Hong, Eun Jig Lee, Sin Gon Kim, Cheol Ryong Ku
European Journal of Endocrinology.2023; 189(2): 225. CrossRef
Proton pump inhibitor use and the risk of metachronous gastric cancer after H. pylori eradication in patients who underwent endoscopic resection for gastric neoplasms: A population‐based cohort study
Eun Jeong Gong, Hye‐Kyung Jung, Bora Lee, Jitaek Hong, Jong Wook Kim, Cheol Min Shin, Young Hoon Youn, Kwang Jae Lee
Alimentary Pharmacology & Therapeutics.2023; 58(7): 668. CrossRef
National Trends in Rotavirus Enteritis among Infants in South Korea, 2010–2021: A Nationwide Cohort
Hyun Jee Lee, Yujin Choi, Jaeyu Park, Yong-Sung Choi, Dong Keon Yon, Do Hyun Kim
Children.2023; 10(9): 1436. CrossRef
Impact of Concomitant Use of Proton Pump Inhibitors and Clopidogrel on Recurrent Stroke and Myocardial Infarction
Yong Kang Lee, Hyun Sun Lim, Youn I Choi, Eun Ju Choe, Seonji Kim, Seng Chan You, Kyung Joo Lee, Yerim Kim, Da Hee Park, Woon Geon Shin, Seung In Seo
Pharmaceuticals.2023; 16(9): 1213. CrossRef
Uric Acid and Risk of Cardiovascular Disease and Mortality: A Longitudinal Cohort Study
Jae Young Kim, Changhwan Seo, Haeyong Pak, Hyunsun Lim, Tae Ik Chang
Journal of Korean Medical Science.2023;[Epub] CrossRef
Occupational characteristics and risk factors associated with endometriosis among Korean female workers
Seunghyun Lee, Seung-Yeon Lee, Wanhyung Lee, Federico Romano
PLOS ONE.2023; 18(10): e0292362. CrossRef
A Nationwide Population‐Based Study for the Recurrence and Comorbidities in Sudden Sensorineural Hearing Loss
Hye Yeon Ko, Hae Jeong Nam, Min Hee Kim
The Laryngoscope.2023;[Epub] CrossRef
Suicidal Thinking Among Patients With Spinal Conditions in South Korea: A Population-Based Cross-Sectional Study
Tak Kyu Oh, Hye Yoon Park, In-Ae Song
Psychiatry Investigation.2023; 20(9): 834. CrossRef
Increased risk of venous and arterial thromboembolism in patients with colorectal cancer receiving cetuximab-based combination chemotherapy: A population-based study in Korea
Ho-Young Yhim, Juhyun Lee, Kyoung Ha Kim, Sang-A Kim, Ji Yun Lee, Hun-Gyu Hwang, Junshik Hong, Jeong-Ok Lee, Soo-Mee Bang
Thrombosis Research.2023; 231: 50. CrossRef
Volatile Anesthetic Use Versus Total Intravenous Anesthesia for Patients Undergoing Heart Valve Surgery: A Nationwide Population-Based Study
Jae-Woo Ju, Ho-Jin Lee, Karam Nam, Seungwook Kim, Hyunsook Hong, Seung Ho Yoo, Seohee Lee, Youn Joung Cho, Yunseok Jeon
Anesthesia & Analgesia.2023;[Epub] CrossRef
Incidence, Morbidity, and Mortality of Achalasia: A Nationwide, Population-Based Cohort Study in South Korea
Ga Hee Kim, Hyungchul Park, Kee Wook Jung, Min-Ju Kim, Ye-Jee Kim, Ji Min Lee, Bong Eun Lee, Yang Won Min, Jeong Hwan Kim, Hee Kyong Na, Ji Yong Ahn, Jeong Hoon Lee, Do Hoon Kim, Kee Don Choi, Ho June Song, Gin Hyug Lee, Hwoon-Yong Jung, Hyun Jin Kim
Gut and Liver.2023; 17(6): 894. CrossRef
Differential Impact of Obesity on the Risk of Diabetes Development in Two Age Groups: Analysis from the National Health Screening Program
Tae Kyung Yoo, Kyung-Do Han, Yang-Hyun Kim, Ga Eun Nam, Sang Hyun Park, Eun-Jung Rhee, Won-Young Lee
Diabetes & Metabolism Journal.2023; 47(6): 846. CrossRef
Association between preoperative modifiable lifestyle factors and mortality after cancer surgery: a population-based cohort study in South Korea
Tak Kyu Oh, In-Ae Song
Annals of Surgical Treatment and Research.2023; 105(4): 179. CrossRef
Classification of long-term clinical course of Parkinson’s disease using clustering algorithms on social support registry database
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Journal of Big Data.2023;[Epub] CrossRef
Association between Proteinuria Status and Risk of Hypertension: A Nationwide Population-Based Cohort Study
Hyungwoo Lee, Moo-Suk Park, Min Kyoung Kang, Tae-Jin Song
Journal of Personalized Medicine.2023; 13(9): 1414. CrossRef
Association of physical activity with the risk of Parkinson's disease in depressive disorder: A nationwide longitudinal cohort study
Ji hyun An, Kyung-do Han, Jin-Hyung Jung, Hong Jin Jeon
Journal of Psychiatric Research.2023; 167: 93. CrossRef
Effect of changes in the hearing aid subsidy on the prevalence of hearing loss in South Korea
Chul Young Yoon, Junhun Lee, Tae Hoon Kong, Young Joon Seo
Frontiers in Neurology.2023;[Epub] CrossRef
Preoperative Body Mass Index, Waist Circumference, and Mortality After Major Cancer Surgery: A Nationwide Cohort Study in Korea
Tak Kyu Oh, In-Ae Song
Journal of Korean Medical Science.2023;[Epub] CrossRef
Characteristics and risk factors of suicide among people who attempted self-harm in South Korea: A longitudinal National Cohort Study in South Korea
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Psychiatry Research.2023; 330: 115613. CrossRef
Association Between Premature Menopause and Cardiovascular Diseases and All‐Cause Mortality in Korean Women
Gyu Bae Lee, Ga Eun Nam, Wonsock Kim, Byoungduck Han, Kyung Hwan Cho, Seon Mee Kim, Youn Seon Choi, Do Hoon Kim, Yong‐Gyu Park, Jin‐Hyung Jung, Kyungdo Han, Yang‐Hyun Kim
Journal of the American Heart Association.2023;[Epub] CrossRef
Risk of gastric cancer among long-term proton pump inhibitor users: a population-based cohort study
Jong Wook Kim, Hye-Kyung Jung, Bora Lee, Cheol Min Shin, Eun Jeong Gong, Jitaek Hong, Young Hoon Youn, Kwang Jae Lee
European Journal of Clinical Pharmacology.2023; 79(12): 1699. CrossRef
Cancer Risk in Elderly Korean Patients with Neurodegenerative Disease and its relation to Type 2 Diabetes
Hee-Cheol Kim, Ji-Hun Kim, Ho-Jun Lee, Yang-Tae Kim, Byeong-Churl Jang
The Open Neurology Journal.2023;[Epub] CrossRef
Performance of Cardiovascular Risk Prediction Models in Korean Patients With New‐Onset Rheumatoid Arthritis: National Cohort Study
Jae Hyun Kim, Gaeun Lee, Jinseub Hwang, Ji‐Won Kim, Jin‐Won Kwon, Yun‐Kyoung Song
Journal of the American Heart Association.2023;[Epub] CrossRef
Impact of Propofol-based Total Intravenous Anesthesia Versus Inhalation Anesthesia on Long-term Survival After Cancer Surgery in a Nationwide Cohort
Susie Yoon, Sun-Young Jung, Myo-Song Kim, Danbi Yoon, Younghae Cho, Yunseok Jeon
Annals of Surgery.2023; 278(6): 1024. CrossRef
Bovine pericardial versus porcine bioprosthetic aortic valves: A nationwide population-based cohort study in Korea
Hong Rae Kim, Ho Jin Kim, Seonok Kim, Yejee Kim, Jung-Min Ahn, Joon Bum Kim, Dae-Hee Kim
The Journal of Thoracic and Cardiovascular Surgery.2023;[Epub] CrossRef
Decreased Risk of Knee Osteoarthritis with Taller Height in an East Asian Population: A Nationwide Cohort Study
Dong Hwan Lee, Hwa Sung Lee, Soo Hyun Jang, Jun-Young Heu, Kyungdo Han, Se-Won Lee
Journal of Clinical Medicine.2023; 13(1): 92. CrossRef
Cost-effectiveness of the anti-vascular endothelial growth factor intravitreal injection and panretinal photocoagulation for patients with proliferative diabetic retinopathy in South Korea
Hyeon-Jeong Lee, Songhee Cho, Jungeun Park, Yan Jin, Hyung Min Kim, Donghyun Jee
BMC Health Services Research.2023;[Epub] CrossRef
Prior Evaluation of Nutritional Status and Mortality in Patients with Sepsis in South Korea
Tak Kyu Oh, In-Ae Song
Nutrients.2023; 15(24): 5040. CrossRef
Increased Risk of Hip Fracture in Patients with Acromegaly: A Nationwide Cohort Study in Korea
Jiwon Kim, Namki Hong, Jimi Choi, Ju Hyung Moon, Eui Hyun Kim, Eun Jig Lee, Sin Gon Kim, Cheol Ryong Ku
Endocrinology and Metabolism.2023; 38(6): 690. CrossRef
Cancer risks in patients with ankylosing spondylitis and the effects of biologic agents: a population-based study
Sang-Yong Eom, Hyun-a Jang, Yo Han Im, Kyung-Hwa Choi, Ji Hyoun Kim
Rheumatology.2023;[Epub] CrossRef
Proton Pump Inhibitor Co-Therapy in Patients with Atrial Fibrillation Treated with Oral Anticoagulants and a Prior History of Upper Gastrointestinal Tract Bleeding
So-Ryoung Lee, Soonil Kwon, Eue-Keun Choi, Jin-Hyung Jung, Kyung-Do Han, Seil Oh, Gregory Y. H. Lip
Cardiovascular Drugs and Therapy.2022; 36(4): 679. CrossRef
Institutional case volume-incorporated mortality risk prediction model for cardiac surgery
Seohee Lee, Eun Jin Jang, Junwoo Jo, Dongnyeok Park, Ho Geol Ryu
Asian Journal of Surgery.2022; 45(1): 189. CrossRef
Does Surgical Ablation of Atrial Fibrillation Benefit Patients Undergoing Bioprosthetic Valve Replacement?
Won Kyung Pyo, Ho Jin Kim, Joon Bum Kim, Sung-Ho Jung, Suk Jung Choo, Cheol Hyun Chung, Jae Won Lee
Seminars in Thoracic and Cardiovascular Surgery.2022; 34(3): 906. CrossRef
Burden of comorbidities and medication use in childbearing women with rheumatic diseases: a nationwide population-based study
Min Kyung Chung, Chan Hee Lee, Jin Su Park, Hyunsun Lim, Jisoo Lee
The Korean Journal of Internal Medicine.2022; 37(6): 1250. CrossRef
Validation of Dynamic Aspartate‐to–Alanine Aminotransferase Ratio for Predicting Liver Disease Mortality
In‐Ae Song, Eun Sun Jang, Tak Kyu Oh
Hepatology Communications.2022; 6(4): 740. CrossRef
Blood Pressure Levels and Risks of Dementia: a Nationwide Study of 4.5 Million People
Chan Joo Lee, Ji-Yeon Lee, Kyungdo Han, Da Hye Kim, Hanna Cho, Kwang Joon Kim, Eun Seok Kang, Bong-Soo Cha, Yong-ho Lee, Sungha Park
Hypertension.2022; 79(1): 218. CrossRef
Continuing regular physical activity and maintaining body weight have a synergistic interaction in improving survival: a population-based cohort study including 6.5 million people
Chang-Hoon Lee, Kyung-Do Han, Da Hye Kim, Min-Sun Kwak
European Journal of Preventive Cardiology.2022; 29(3): 547. CrossRef
Liver enzymes and risk of ocular motor cranial nerve palsy: a nationwide population-based study
Joonhyoung Kim, Kyungdo Han, Juhwan Yoo, Kyung-Ah Park, Sei Yeul Oh
Neurological Sciences.2022; 43(5): 3395. CrossRef
Underutilisation of prophylactic G-CSF in breast cancer patients receiving adjuvant docetaxel/cyclophosphamide chemotherapy
Minhee Ku, Nam Kyung Je
Journal of Chemotherapy.2022; 34(8): 534. CrossRef
Epidemiologic study of bladder and urethral injury in Korea: A nationwide population-based study
Bum Sik Tae, Young Eun Yoon, Woong Na, Kyung Jin Oh, Sung Yul Park, Jae Young Park, Hong Sang Moon
Investigative and Clinical Urology.2022; 63(1): 92. CrossRef
Acromegaly and cardiovascular outcomes: a cohort study
Sangmo Hong, Kyung-Soo Kim, Kyungdo Han, Cheol-Young Park
European Heart Journal.2022; 43(15): 1491. CrossRef
Pericardial Versus Porcine Valves for Surgical Aortic Valve Replacement
Hong Ju Shin, Wan Kee Kim, Jin Kyoung Kim, Joon Bum Kim, Sung-Ho Jung, Suk Jung Choo, Cheol Hyun Chung, Jae Won Lee
Korean Circulation Journal.2022; 52(2): 136. CrossRef
Effect of obesity and metabolic health on urolithiasis: A nationwide population-based study
Changil Choi, Jong Keun Kim, Kyungdo Han, Young Goo Lee, Jun Hyun Han
Investigative and Clinical Urology.2022; 63(1): 63. CrossRef
Comprehensive risk assessment for hospital-acquired pneumonia: sociodemographic, clinical, and hospital environmental factors associated with the incidence of hospital-acquired pneumonia
Bo-Guen Kim, Minwoong Kang, Jihyun Lim, Jin Lee, Danbee Kang, Minjung Kim, Jinhee Kim, Hyejeong Park, Kyung Hoon Min, Juhee Cho, Kyeongman Jeon
BMC Pulmonary Medicine.2022;[Epub] CrossRef
Metabolic Disease Incidence After Allogeneic Stem Cell Transplantation: A Nationwide Korean Case-Control Study
Jeonghoon Ha, See Hyun Park, Sung-Soo Park, Seunghoon Han
The Journal of Clinical Endocrinology & Metabolism.2022; 107(4): 943. CrossRef
Development of eClaim system for private indemnity health insurance in South Korea: Compatibility and interoperability
Sungchul Bae, Byoung-Kee Yi
Health Informatics Journal.2022;[Epub] CrossRef
Incidence of Depression after Traumatic Brain Injury: A Nationwide Longitudinal Study of 2.2 Million Adults
Yoonjeong Choi, Eun Young Kim, Jiyu Sun, Han-Kyoul Kim, Ye Seol Lee, Byung-Mo Oh, Hye Yoon Park, Ja-Ho Leigh
Journal of Neurotrauma.2022; 39(5-6): 390. CrossRef
Female Reproductive Factors and the Risk of Bronchiectasis: A Nationwide Population-Based Longitudinal Study
Bumhee Yang, Dong-Hwa Lee, Kyungdo Han, Hayoung Choi, Hyung Koo Kang, Dong Wook Shin, Hyun Lee
Biomedicines.2022; 10(2): 303. CrossRef
Clinical outcomes of early closure versus conservative strategy after diagnosis with atrial septal defect: a nationwide population-based cohort study
Sun-Yang Min, Ji Sung Lee, Duk-Woo Park, Jong-Min Song
European Journal of Cardio-Thoracic Surgery.2022;[Epub] CrossRef
Risk of Osteoporotic Fractures Among Obese Women Based on Body Mass Index and Waist Circumference: A Nationwide Cohort in South Korea
Gyeongsil Lee, Seulggie Choi, Yoosun Cho, Sang Min Park
Clinical Nutrition Research.2022; 11(1): 32. CrossRef
Long-term prognosis and causes of death among survivors after out-of-hospital cardiac arrest: A population-based longitudinal study
Yongil Cho, Jaehoon Oh, Jeong-Hun Shin, Byung Sik Kim, Jin-Kyu Park, Jun Ho Lee, Jae Hwan Kim, Minae Park
Resuscitation.2022; 173: 31. CrossRef
Blood pressure and mortality after percutaneous coronary intervention: a population-based cohort study
Chung-woo Lee, Joo Kyung Lee, Yeon Joo Choi, Hyunjin Kim, Kyungdo Han, Jin-hyung Jung, Do Hoon Kim, Joo-Hyun Park
Scientific Reports.2022;[Epub] CrossRef
Analysis of Severe Hypoglycemia Among Adults With Type 2 Diabetes and Nonalcoholic Fatty Liver Disease
Ji-Yeon Lee, Young-eun Kim, Kyungdo Han, Eugene Han, Byung Wan Lee, Eun Seok Kang, Bong-Soo Cha, Seung-Hyun Ko, Yong-ho Lee
JAMA Network Open.2022; 5(2): e220262. CrossRef
Hip Fracture Risk According to Diabetic Kidney Disease Phenotype in a Korean Population
Seung Eun Lee, Juhwan Yoo, Kyoung-Ah Kim, Kyungdo Han, Han Seok Choi
Endocrinology and Metabolism.2022; 37(1): 148. CrossRef
Non-Alcoholic Fatty Liver Disease Defined by Fatty Liver Index and Incidence of Heart Failure in the Korean Population: A Nationwide Cohort Study
Byoungduck Han, Gyu Bae Lee, Sun Young Yim, Kyung-Hwan Cho, Koh Eun Shin, Jung-Hwan Kim, Yong-Gyu Park, Kyung-Do Han, Yang-Hyun Kim
Diagnostics.2022; 12(3): 663. CrossRef
Contact with the health care system prior to suicide: A nationwide population-based analysis using linkage national death certificates and national health insurance data
Eun Jee Park, Nam Ju Ji, Weon Young Lee
Journal of Psychiatric Research.2022; 149: 226. CrossRef
Association between asthma or chronic obstructive pulmonary disease and chronic otitis media
Sung Kyun Kim, Seok Jin Hong, Dae Myoung Yoo, Chanyang Min, Hyo Geun Choi
Scientific Reports.2022;[Epub] CrossRef
Prognosis of pregnancy after breast cancer diagnosis according to the type of treatment: A population-based study in Korea by the SMARTSHIP group
Soo Youn Bae, Jihyoun Lee, Ji Sung Lee, Jae Sun Yoon, Ku Sang Kim, Yoo Seok Kim, Zisun Kim, Jun Won Min, Eun-Jung Shim, Ilkyun Lee, Min Hyuk Lee, Sungmin Park
The Breast.2022; 63: 46. CrossRef
Fracture risk and impact of osteoporosis in patients with Parkinson’s disease: a nationwide database study
Tae-lim Kim, Seong Jun Byun, Min Yong Seong, Byung-Mo Oh, Sang Jun Park, Han Gil Seo
Journal of Bone and Mineral Metabolism.2022; 40(4): 602. CrossRef
Risk prediction models incorporating institutional case volume for mortality after hip fracture surgery in the elderly
Seokha Yoo, Eun Jin Jang, Junwoo Jo, Hannah Lee, Yoonbin Hwang, Ho Geol Ryu
Archives of Orthopaedic and Trauma Surgery.2022; 143(5): 2307. CrossRef
Association of weight change following smoking cessation with the risk of tuberculosis development: A nationwide population-based cohort study
Seung Hoon Kim, Yong-Moon Park, Kyungdo Han, Seung Hyun Ko, Shin Young Kim, So Hyang Song, Chi Hong Kim, Kyu Yeon Hur, Sung Kyoung Kim, Juan F. Orueta
PLOS ONE.2022; 17(4): e0266262. CrossRef
Epidemiology of Acute Leukemia among Children with Down Syndrome in Korea
Young Bae Choi, Keon Hee Yoo
Cancer Research and Treatment.2022; 54(2): 572. CrossRef
The Effect of Alcohol Drinking on Metabolic Syndrome and Obesity in Koreans: Big Data Analysis
Eun Jung Park, Hye Jung Shin, Sung Soo Kim, Ki Eun Kim, Sun Hyun Kim, Youl Ri Kim, Kyong Mee Chung, Kyung Do Han
International Journal of Environmental Research and Public Health.2022; 19(9): 4949. CrossRef
Prolonged or Transition to Metabolically Unhealthy Status, Regardless of Obesity Status, Is Associated with Higher Risk of Cardiovascular Disease Incidence and Mortality in Koreans
Juhee Lee, So-Young Kwak, Dahyun Park, Ga-Eun Kim, Clara Yongjoo Park, Min-Jeong Shin
Nutrients.2022; 14(8): 1644. CrossRef
Lifestyle, body mass index, diabetes, and the risk of pancreatic cancer in a nationwide population-based cohort study with 7.4 million Korean subjects
Byung Kyu Park, Jeong Hun Seo, Jae Bock Chung, Jung Kyu Choi
British Journal of Cancer.2022; 127(3): 549. CrossRef
Cardiovascular Risk and Treatment Outcomes in Severe Hypercholesterolemia: A Nationwide Cohort Study
Chan Joo Lee, Sanghyun Park, Kyungdo Han, Sang‐Hak Lee
Journal of the American Heart Association.2022;[Epub] CrossRef
Association between Smoking Status and Incident Non-Cystic Fibrosis Bronchiectasis in Young Adults: A Nationwide Population-Based Study
Bumhee Yang, Kyungdo Han, Bongseong Kim, Hyung Koo Kang, Jung Soo Kim, Eung-Gook Kim, Hayoung Choi, Hyun Lee
Journal of Personalized Medicine.2022; 12(5): 691. CrossRef
Clinical Indication of Aspirin Associated With Reduced Risk of Liver Cancer in Chronic Hepatitis B: A Nationwide Cohort Study
Byungyoon Yun, Sang Hoon Ahn, Jin-Ha Yoon, Beom Kyung Kim
American Journal of Gastroenterology.2022; 117(5): 758. CrossRef
Association between Attention Deficit Hyperactivity Disorder Medication and Depression: A 10-year Follow-up Self-controlled Case Study
Yunhye Oh, Yoo-Sook Joung, Jinseob Kim
Clinical Psychopharmacology and Neuroscience.2022; 20(2): 320. CrossRef
Association of Chronic Hepatitis B Infection and Antiviral Treatment With the Development of the Extrahepatic Malignancies: A Nationwide Cohort Study
Dong Hyeon Lee, Sung Won Chung, Jeong-Hoon Lee, Hwi Young Kim, Goh Eun Chung, Mi-Sook Kim, Bo Ram Yang, Joon Yeul Nam, Yun Bin Lee, Yoon Jun Kim, Jung-Hwan Yoon
Journal of Clinical Oncology.2022; 40(29): 3394. CrossRef
Cancer risk in the residents of a town near three industrial waste incinerators in Korea: a retrospective cohort study
Kyung-Hwa Choi, Hyungryul Lim, Sanghyuk Bae, Mina Ha, Ho-Jang Kwon, Mira Yoon, Seonmi Hong, Sang-Yong Eom, Yong-Dae Kim, Heon Kim
International Archives of Occupational and Environmental Health.2022; 95(9): 1829. CrossRef
Triglyceride-Glucose Index Is a Useful Marker for Predicting Future Cardiovascular Disease and Mortality in Young Korean Adults: A Nationwide Population-Based Cohort Study
Yun Kyung Cho, Kyung-do Han, Hwi Seung Kim, Chang Hee Jung, Joong-Yeol Park, Woo Je Lee
Journal of Lipid and Atherosclerosis.2022; 11(2): 178. CrossRef
Annual Trends in the Incidence and Prevalence of Alzheimer's Disease in South Korea: A Nationwide Cohort Study
Min Seok Baek, Han-Kyeol Kim, Kyungdo Han, Hyuk-Sung Kwon, Han Kyu Na, Chul Hyoung Lyoo, Hanna Cho
Frontiers in Neurology.2022;[Epub] CrossRef
Risk Factors of Incident Lung Cancer in Patients with Non-Cystic Fibrosis Bronchiectasis: A Korean Population-Based Study
Youlim Kim, Kyungdo Han, Juhwan Yoo, Hyung Koo Kang, Tai Sun Park, Dong Won Park, Ji Young Hong, Ji-Yong Moon, Sang-Heon Kim, Tae Hyung Kim, Kwang Ha Yoo, Jang Won Sohn, Ho Joo Yoon, Hayoung Choi, Hyun Lee
Cancers.2022; 14(11): 2604. CrossRef
Association Between Hypertension and Incident Infective Endocarditis
Gyu Bae Lee, Koh Eun Shin, Kyungdo Han, Ho-Sung Son, Jae-Seung Jung, Yang-Hyun Kim, Hee-Jung Kim
Hypertension.2022; 79(7): 1466. CrossRef
Risk of secondary nonhematologic malignancies after allogeneic stem cell transplantation: A nationwide case‐control cohort study
Sung‐Soo Park, Si‐Hyun Park, Seunghoon Han
International Journal of Cancer.2022; 151(7): 1024. CrossRef
Acute myocardial infarction risk in multiple sclerosis and neuromyelitis optica spectrum disorder: A nationwide cohort study in South Korea
Eun Bin Cho, Yohwan Yeo, Jin-Hyung Jung, Su-Min Jeong, Kyungdo Han, Jeong Hoon Yang, Dong Wook Shin, Ju-Hong Min
Multiple Sclerosis Journal.2022; 28(12): 1849. CrossRef
Nationwide population-based incidence of cancer among patients with HIV/AIDS in South Korea
Soon Ok Lee, Jeong Eun Lee, Shinwon Lee, Sun Hee Lee, Jin Suk Kang, Hyunjin Son, Hyungi Lee, Jinmi Kim
Scientific Reports.2022;[Epub] CrossRef
Association between migraine and risk of ocular motor cranial nerve palsy
Soolienah Rhiu, Kyungdo Han, Juhwan Yoo, Kyung-Ah Park, Sei Yeul Oh
Scientific Reports.2022;[Epub] CrossRef
Statin use and risk of progression to liver cirrhosis in chronic hepatitis B independent of conventional risk factors: A nationwide study
Byungyoon Yun, Sang Hoon Ahn, Jin‐Ha Yoon, Beom Kyung Kim
Hepatology Communications.2022; 6(9): 2455. CrossRef
Association Between Metabolic Syndrome and the Risk of Colorectal Cancer Diagnosed Before Age 50 Years According to Tumor Location
Eun Hyo Jin, Kyungdo Han, Dong Ho Lee, Cheol Min Shin, Joo Hyun Lim, Yoon Jin Choi, Kichul Yoon
Gastroenterology.2022; 163(3): 637. CrossRef
A positive faecal immunochemical test result and its association with the incidence of rheumatoid arthritis, systemic lupus erythematosus, and psoriatic arthritis: an analysis of one-million national colorectal cancer screening programme results
Choong-Kyun Noh, Eunyoung Lee, Bumhee Park, Sung Soo Ahn
BMC Medicine.2022;[Epub] CrossRef
Obesity Fact Sheet in Korea, 2021: Trends in Obesity Prevalence and Obesity-Related Comorbidity Incidence Stratified by Age from 2009 to 2019
Ye Seul Yang, Byoung-Duck Han, Kyungdo Han, Jin-Hyung Jung, Jang Won Son
Journal of Obesity & Metabolic Syndrome.2022; 31(2): 169. CrossRef
Venous Thromboembolism Risk in Asian Patients with Inflammatory Bowel Disease: A Population-Based Nationwide Inception Cohort Study
Su Young Kim, Yeon Seo Cho, Hyun-Soo Kim, Jung Kuk Lee, Hee Man Kim, Hong Jun Park, Hyunil Kim, Jihoon Kim, Dae Ryong Kang
Gut and Liver.2022; 16(4): 555. CrossRef
Impact of Wildfire Smoke Exposure on Health in Korea
Kihyun Lee, Sung-Soo Oh, Kyoung Sook Jeong, Yeon-Soon Ahn, Sei Jin Chang, Se Hwa Hong, Dae Ryong Kang, Sung-Kyung Kim, Sang-Baek Koh
Yonsei Medical Journal.2022; 63(8): 774. CrossRef
Risk for Behçet’s disease gauged via high-density lipoprotein cholesterol: a nationwide population-based study in Korea
Yeong Ho Kim, Hyun Jee Kim, Jin Woo Park, Kyung Do Han, Yong Gyu Park, Young Bok Lee, Ji Hyun Lee
Scientific Reports.2022;[Epub] CrossRef
Analysis of Mortality in Intracerebral Hemorrhage Patients with Hyperacute Ischemic Stroke Treated Using Thrombolytic Therapy: A Nationwide Population-based Cohort Study in South Korea
Hyun-Young Choi, Yongil Cho, Wonhee Kim, Yang-Ki Minn, Gu-Hyun Kang, Yong-Soo Jang, Yoonje Lee, Jae-Guk Kim, Jihoon Kim, Youngsuk Cho, Hyungoo Shin, Shinje Moon, Chiwon Ahn, Juncheol Lee, Dong-Geum Shin, Jae-Keun Park
Journal of Personalized Medicine.2022; 12(8): 1260. CrossRef
Institutional case volume and mortality after aortic and mitral valve replacement: a nationwide study in two Korean cohorts
Karam Nam, Eun Jin Jang, Jun Woo Jo, Jiwon You, Jung-Bin Park, Ho Geol Ryu
Journal of Cardiothoracic Surgery.2022;[Epub] CrossRef
Effect of metabolic dysfunction‐associated fatty liver disease on liver cancer risk in a population with chronic hepatitis B virus infection: A nationwide study
Byungyoon Yun, Sang Hoon Ahn, Juyeon Oh, Jin‐Ha Yoon, Beom Kyung Kim
Hepatology Research.2022; 52(12): 975. CrossRef
Non–Cystic Fibrosis Bronchiectasis Increases the Risk of Lung Cancer Independent of Smoking Status
Hayoung Choi, Hye Yun Park, Kyungdo Han, Juhwan Yoo, Sun Hye Shin, Bumhee Yang, Youlim Kim, Tai Sun Park, Dong Won Park, Ji-Yong Moon, Seung Won Ra, Sang-Heon Kim, Tae-Hyung Kim, Yeon-Mok Oh, Ho Joo Yoon, Jang Won Sohn, Hyun Lee
Annals of the American Thoracic Society.2022; 19(9): 1551. CrossRef
Real-World Prescription Patterns and Barriers Related to the Use of Sodium-Glucose Cotransporter 2 Inhibitors among Korean Patients with Type 2 Diabetes Mellitus and Cardiovascular Disease
Jong Ha Baek, Ye Seul Yang, Seung-Hyun Ko, Kyung Do Han, Jae Hyeon Kim, Min Kyong Moon, Jong Suk Park, Byung-Wan Lee, Tae Jung Oh, Suk Chon, Jong Han Choi, Kyu Yeon Hur
Diabetes & Metabolism Journal.2022; 46(5): 701. CrossRef
Editor's Choice – Effect of Physical Activity and Tobacco Use on Mortality and Morbidity in Patients with Peripheral Arterial Disease After Revascularisation: A Korean Nationwide Population Based Cohort Study
Seungwoo Cha, Sherry L. Grace, Kyungdo Han, Bongseong Kim, Nam-Jong Paik, Won-Seok Kim
European Journal of Vascular and Endovascular Surgery.2022; 64(4): 417. CrossRef
Augmented risk of ischemic stroke in hypertrophic cardiomyopathy patients without documented atrial fibrillation
You-Jung Choi, Bongseong Kim, Tae-Min Rhee, Hyun-Jung Lee, Heesun Lee, Jun-Bean Park, Seung-Pyo Lee, Kyung-Do Han, Yong-Jin Kim, Hyung-Kwan Kim
Scientific Reports.2022;[Epub] CrossRef
Surgical ablation for atrial fibrillation during aortic and mitral valve surgery: A nationwide population-based cohort study
Ho Jin Kim, Ye-Jee Kim, Minju Kim, Jae Suk Yoo, Dae-Hee Kim, Duk-Woo Park, Sung-Ho Jung, Suk Jung Choo, Joon Bum Kim
The Journal of Thoracic and Cardiovascular Surgery.2022;[Epub] CrossRef
Depression in patients with inflammatory bowel disease is associated with increased risk of dementia and Parkinson’s disease: A nationwide, population-based study
Kookhwan Choi, Hyun Jung Lee, Kyungdo Han, Seong-Joon Koh, Jong Pil Im, Joo Sung Kim
Frontiers in Medicine.2022;[Epub] CrossRef
Individual socioeconomic status and risk of out‐of‐hospital cardiac arrest: A nationwide case–control analysis
Sun Young Lee, Jeong Ho Park, Young Ho Choi, Jungah Lee, Young Sun Ro, Ki Jeong Hong, Kyoung Jun Song, Sang Do Shin
Academic Emergency Medicine.2022; 29(12): 1438. CrossRef
Impact of nationwide hepatocellular carcinoma surveillance on the prognosis in patients with chronic liver disease
Won Sohn, Danbee Kang, Minwoong Kang, Eliseo Guallar, Juhee Cho, Yong-Han Paik
Clinical and Molecular Hepatology.2022; 28(4): 851. CrossRef
Population Prevalence, Cancer Risk, and Mortality Risk of Turner Syndrome in South Korean Women Based on National Health Insurance Service Data
Sung Eun Kim, Sang Hyun Park, Kyungdo Han, Won Kyoung Cho, Byung-Kyu Suh, Yong-Gyu Park
Yonsei Medical Journal.2022; 63(11): 991. CrossRef
Effects of Endocrine Therapy on Cardiovascular Diseases and Type 2 Diabetes Among Breast Cancer Survivors: The National Health Insurance Service Database of Korea
Ji‐Eun Kim, Jaesung Choi, JooYong Park, Wonshik Han, Daehee Kang, Ji‐Yeob Choi
Journal of the American Heart Association.2022;[Epub] CrossRef
Association between exercise and risk of cardiovascular diseases in patients with non-cystic fibrosis bronchiectasis
Hayoung Choi, Sang Hyuk Kim, Kyungdo Han, Tai Sun Park, Dong Won Park, Ji-Yong Moon, Sang-Heon Kim, Tae-Hyung Kim, Jang Won Sohn, Ho Joo Yoon, Hyun Lee
Respiratory Research.2022;[Epub] CrossRef
Development and Evaluation of Machine Learning-Based High-Cost Prediction Model Using Health Check-Up Data by the National Health Insurance Service of Korea
Yeongah Choi, Jiho An, Seiyoung Ryu, Jaekyeong Kim
International Journal of Environmental Research and Public Health.2022; 19(20): 13672. CrossRef
Comparing Non-Communicable Disease Risk Factors in Asian Migrants and Native Koreans among the Asian Population
Heng Piao, Jae Moon Yun, Aesun Shin, Belong Cho, Daehee Kang
Biomolecules & Therapeutics.2022; 30(6): 603. CrossRef
Chronic kidney disease as a risk factor for abdominal aortic aneurysm: a nationwide population-based study
Kang-woong Jun, Ju-hwan Yoo, Kyung-jai Ko, Hyung-jin Cho, Mi-hyeong Kim, Kyung-do Han, Jeong-kye Hwang
Annals of Surgical Treatment and Research.2022; 103(5): 297. CrossRef
Epidemiology and Management Trend of Renal Trauma: Results of a Nationwide Population-Based Study
Bum Sik Tae, Hoon Ah Jang, Jihyeong Yu, Kyung-Jin Oh, Kyung Hyun Moon, Jae Young Park
Journal of Korean Medical Science.2022;[Epub] CrossRef
Low-to-moderate atmospheric ozone levels are negatively correlated with hospital visits by asthma patients
Soyeon Lee, Minhyeok Lee
Medicine.2022; 101(45): e31737. CrossRef
Acute Pancreatitis Increases the Risk of Gastrointestinal Cancer in Type 2 Diabetic Patients: A Korean Nationwide Cohort Study
Jin Ho Choi, Woo Hyun Paik, Dong Kee Jang, Min Kyu Kim, Ji Kon Ryu, Yong-Tae Kim, Kyungdo Han, Sang Hyub Lee
Cancers.2022; 14(22): 5696. CrossRef
Fasting Glucose Variability and the Risk of Dementia in Individuals with Diabetes: A Nationwide Cohort Study
Da Young Lee, Jaeyoung Kim, Sanghyun Park, So Young Park, Ji Hee Yu, Ji A Seo, Nam Hoon Kim, Hye Jin Yoo, Sin Gon Kim, Kyung Mook Choi, Sei Hyun Baik, Kyungdo Han, Nan Hee Kim
Diabetes & Metabolism Journal.2022; 46(6): 923. CrossRef
The association between changes in hepatic steatosis and hepatic fibrosis with cardiovascular outcomes and mortality in patients with New-Onset type 2 Diabetes: A nationwide cohort study
Jiyun Park, Gyuri Kim, Bong-Sung Kim, Kyung-Do Han, So Yoon Kwon, So Hee Park, You-Bin Lee, Sang-Man Jin, Jae Hyeon Kim
Diabetes Research and Clinical Practice.2022; 194: 110191. CrossRef
Long-term outcomes of preterm infants in the first 6 years of life: a nationwide population-based study in Korea
Ju Hyun Jin, Sung Hee Lee, Tae Mi Youk, Shin Won Yoon
European Journal of Pediatrics.2022; 182(2): 641. CrossRef
Risk of malignancy in patients with psoriasis according to treatment modalities in Korea: a nationwide cohort study
Ji Youn Hong, Juhee Ahn, Sungho Won, Sung Min Kim, Young Ah Cho, Chang Yong Kim, Jae Young Sung, Da-Ae Yu, Yang Won Lee, Yong Beom Choe
Scientific Reports.2022;[Epub] CrossRef
Association between physical activity and risk of renal function decline and mortality in community-dwelling older adults: a nationwide population-based cohort study
Hyunsuk Kim, Mun Jung Ko, Chi-Yeon Lim, Eunjin Bae, Young Youl Hyun, Sungjin Chung, Soon Hyo Kwon, Jang-Hee Cho, Kyung Don Yoo, Woo Yeong Park, In O Sun, Byung Chul Yu, Gang-Jee Ko, Jae Won Yang, Won Min Hwang, Sang Heon Song, Sung Joon Shin, Yu Ah Hong
BMC Geriatrics.2022;[Epub] CrossRef
The associations between changes in hepatic steatosis and heart failure and mortality: a nationwide cohort study
Jiyun Park, Gyuri Kim, Hasung Kim, Jungkuk Lee, Sang-Man Jin, Jae Hyeon Kim
Cardiovascular Diabetology.2022;[Epub] CrossRef
Incidence of edentulism among older adults using the Korean National Health Insurance Service database, 2013-2018
Hyeonjeong Go, Eun-Kyong Kim, Hoi-In Jung, Song Vogue Ahn, Hosung Shin, Atsuo Amano, Youn-Hee Choi
Epidemiology and Health.2022; 44: e2022091. CrossRef
Risk of Neurodegenerative Diseases in Patients With Acromegaly
Sangmo Hong, Kyungdo Han, Kyung-Soo Kim, Cheol-Young Park
Neurology.2022;[Epub] CrossRef
Association between Body Mass Index and Risk of Coronavirus Disease 2019 (COVID-19): A Nationwide Case-control Study in South Korea
Chan-Young Jung, Haeyong Park, Dong Wook Kim, Hyunsun Lim, Jung Hyun Chang, Yoon Jung Choi, Seong Woo Kim, Tae Ik Chang
Clinical Infectious Diseases.2021; 73(7): e1855. CrossRef
Increased risk of cancer in patients with retinal vein occlusion: a 12-year nationwide cohort study
Min Seok Kim, Joon Hee Cho, Seong Jun Byun, Chang-Mo Oh, Kyu Hyung Park, Sang Jun Park
British Journal of Ophthalmology.2021; 105(12): 1705. CrossRef
Conditional relative survival and competing mortality in patients who underwent surgery for lung cancer: A nationwide cohort study
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International Journal of Cancer.2021; 148(3): 626. CrossRef
Impact of Benign Prostatic Hyperplasia and/or Prostatitis on the Risk of Prostate Cancer in Korean Patients
Sung Han Kim, Whi-An Kwon, Jae Young Joung
The World Journal of Men's Health.2021; 39(2): 358. CrossRef
High prevalence of physical inactivity after heart valve surgery and its association with long-term mortality: A nationwide cohort study
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European Journal of Preventive Cardiology.2021; 28(7): 749. CrossRef
Risk of cancer incidence in patients with idiopathic pulmonary fibrosis: A nationwide cohort study
Hong Yeul Lee, Jinwoo Lee, Chang‐Hoon Lee, Kyungdo Han, Sun Mi Choi
Respirology.2021; 26(2): 180. CrossRef
Association of physical activity with all-cause and cardiovascular mortality in 7666 adults with hypertrophic cardiomyopathy (HCM): more physical activity is better
Soonil Kwon, Hyun-Jung Lee, Kyung-Do Han, Da Hye Kim, Seung-Pyo Lee, In-Chang Hwang, Yeonyee Yoon, Jun-Bean Park, Heesun Lee, Soongu Kwak, Seokhun Yang, Goo-Yeong Cho, Yong-Jin Kim, Hyung-Kwan Kim, Steve R Ommen
British Journal of Sports Medicine.2021; 55(18): 1034. CrossRef
Traditional medicine for the treatment of common cold in Korean adults: A nationwide population-based study
Hyungtae Kim, Jun-Yong Choi, Minna Hong, Hae Sun Suh
Integrative Medicine Research.2021; 10(1): 100458. CrossRef
Physical activity after ischemic stroke and its association with adverse outcomes: A nationwide population-based cohort study
Seong-Min Kang, Sun-Hyung Kim, Kyung-Do Han, Nam-Jong Paik, Won-Seok Kim
Topics in Stroke Rehabilitation.2021; 28(3): 170. CrossRef
Obesity and breast cancer risk for pre- and postmenopausal women among over 6 million Korean women
Jae Won Park, Kyungdo Han, Dong Wook Shin, Yohwan Yeo, Ji Won Chang, Jung Eun Yoo, Su-Min Jeong, Se-Kyung Lee, Jai Min Ryu, Yong-Moon Park
Breast Cancer Research and Treatment.2021; 185(2): 495. CrossRef
Association of Hypertension With the Risk and Severity of Epistaxis
Hayoung Byun, Jae Ho Chung, Seung Hwan Lee, Jiin Ryu, Changsun Kim, Jeong-Hun Shin
JAMA Otolaryngology–Head & Neck Surgery.2021; 147(1): 34. CrossRef
The risk of hip fractures in individuals over 50 years old with prediabetes and type 2 diabetes – A longitudinal nationwide population-based study
Ho Youn Park, Kyoungdo Han, Youngwoo Kim, Yoon Hwan Kim, Yoo Joon Sur
Bone.2021; 142: 115691. CrossRef
Increased atrial fibrillation risk in Parkinson’s disease: A nationwide population‐based study
Seokmoon Han, Inki Moon, Eue‐Keun Choi, Kyung‐Do Han, Hae‐Chan Cho, Seo‐Young Lee, Seokhun Yang, Soonil Kwon, You‐jung Choi, Hyun‐Jung Lee, Euijae Lee, So‐Ryung Lee, Seil Oh
Annals of Clinical and Translational Neurology.2021; 8(1): 238. CrossRef
Risk of Cancer Following the Use of N-Nitrosodimethylamine (NDMA) Contaminated Ranitidine Products: A Nationwide Cohort Study in South Korea
Hong Jin Yoon, Jie-Hyun Kim, Gi Hyeon Seo, Hyojin Park
Journal of Clinical Medicine.2021; 10(1): 153. CrossRef
The insulin resistance by triglyceride glucose index and risk for dementia: population-based study
Sangmo Hong, Kyungdo Han, Cheol-Young Park
Alzheimer's Research & Therapy.2021;[Epub] CrossRef
Ten-Year Relative Survival From the Diagnosis of Parkinson's Disease: A Nationwide Database Study
Han Gil Seo, Seong Jun Byun, Byung-Mo Oh, Sang Jun Park
Journal of the American Medical Directors Association.2021; 22(8): 1757. CrossRef
Short- and long-term exposure to air pollution and lack of sunlight are associated with an increased risk of depression: A nested case-control study using meteorological data and national sample cohort data
So Young Kim, Minji Bang, Jee Hye Wee, Chanyang Min, Dae Myoung Yoo, Sang-Min Han, Seungdo Kim, Hyo Geun Choi
Science of The Total Environment.2021; 757: 143960. CrossRef
Associations between metabolic syndrome and type of dementia: analysis based on the National Health Insurance Service database of Gangwon province in South Korea
Yeo Jin Kim, Sang Mi Kim, Dae Hyun Jeong, Sang-Kyu Lee, Moo-Eob Ahn, Ohk-Hyun Ryu
Diabetology & Metabolic Syndrome.2021;[Epub] CrossRef
Repeatedly elevated γ-glutamyltransferase levels are associated with an increased incidence of digestive cancers: A population-based cohort study
Chang-Hoon Lee, Kyungdo Han, Da Hye Kim, Min-Sun Kwak
World Journal of Gastroenterology.2021; 27(2): 176. CrossRef
Incidence and prevalence of systemic lupus erythematosus among Korean women in childbearing years: A nationwide population-based study
Min Kyung Chung, Jin Su Park, Hyunsun Lim, Chan Hee Lee, Jisoo Lee
Lupus.2021; 30(4): 674. CrossRef
Effect of institutional case volume on mid-term mortality after coronary artery bypass grafting surgery
Seohee Lee, Eun Jin Jang, Junwoo Jo, Dongyeon Jang, Bo Rim Kim, Ho Geol Ryu
General Thoracic and Cardiovascular Surgery.2021; 69(9): 1275. CrossRef
Rheumatoid arthritis in low‐level toluene‐exposed workers based on nationwide medical surveillance data in Korea
Young‐Sun Min, Sungho Lee, Mingi Kim, Yeon‐Soon Ahn
American Journal of Industrial Medicine.2021; 64(4): 245. CrossRef
Status of Diabetic Neuropathy in Korea: A National Health Insurance Service-National Sample Cohort Analysis (2006 to 2015)
Seong-Su Moon, Chong Hwa Kim, Seon Mee Kang, Eun Sook Kim, Tae Jung Oh, Jae-Seung Yun, Ho Chan Cho, Dae Jung Kim, Tae Sun Park
Diabetes & Metabolism Journal.2021; 45(1): 115. CrossRef
Risk factors associated with failure of total ankle arthroplasty: a nationwide cohort study
Dong Hun Suh, Kyungdo Han, Jin Woo Lee, Hak Jun Kim, Bongsung Kim, Bong Mo Koo, Hak Kyu Kim, Gi Won Choi
Scientific Reports.2021;[Epub] CrossRef
Impact of body mass index on development of nontuberculous mycobacterial pulmonary disease
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European Respiratory Journal.2021; 57(2): 2000454. CrossRef
Survival in untreated hepatocellular carcinoma: A national cohort study
Young Ae Kim, Danbee Kang, Hyeyoung Moon, Donghyun Sinn, Minwoong Kang, Sang Myung Woo, Yoon Jung Chang, Boram Park, Sun-Young Kong, Eliseo Guallar, Soo-Yong Shin, Geunyeon Gwak, Joung Hwan Back, Eun Sook Lee, Juhee Cho, Gianfranco D. Alpini
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Early and Two-year Outcomes after Sutureless and Conventional Aortic Valve Replacement: a Nationwide Population-based Study
Jae Woong Choi, Ho Jin Kim, Joon Bum Kim, Sak Lee, Cheong Lim, Byung Chul Chang, Youshin Suh, Na Rae Lee, Ho Young Hwang
Journal of Korean Medical Science.2021;[Epub] CrossRef
Assessment of Trends in the Incidence Rates of Central Retinal Artery Occlusion in Korea From 2002 to 2015
Jongshin Kim, Seong Jun Byun, Se Joon Woo, Kyu Hyung Park, Sang Jun Park
JAMA Ophthalmology.2021; 139(4): 399. CrossRef
The incidence of myocardial infarction and stroke in head and neck cancer patients
Hyun-Keun Kwon, Kyung-Do Han, Yong-Il Cheon, Sung-Chan Shin, Minhyung Lee, Eui-Suk Sung, Jin-Choon Lee, Byung-Joo Lee
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Long-term impacts of appendectomy associated with increased incidence of inflammatory bowel disease, infection, and colorectal cancer
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International Journal of Colorectal Disease.2021; 36(8): 1643. CrossRef
Severe hypoglycemia and the risk of end stage renal disease in type 2 diabetes
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Proteinuria Is Associated with the Development of Crohn’s Disease: A Nationwide Population-Based Study
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Journal of Clinical Medicine.2021; 10(4): 799. CrossRef
Lifestyle is associated with atrial fibrillation development in patients with type 2 diabetes mellitus
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Determining the association between repeatedly elevated serum gamma‐glutamyltransferase levels and risk of respiratory cancer: A nationwide population‐based cohort study
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Cancer Medicine.2021; 10(4): 1366. CrossRef
The Repeatedly Elevated Fatty Liver Index Is Associated With Increased Mortality: A Population-Based Cohort Study
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Frontiers in Endocrinology.2021;[Epub] CrossRef
A nationwide population-based study in South Korea on a relationship between height and anosmia
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Scientific Reports.2021;[Epub] CrossRef
Effect of healthcare benefits on short‐term adherence of positive airway pressure therapy
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Comparative Surgical Outcomes of Prosthetic and Native Valve Endocarditis
Won Kyung Pyo, Ho Jin Kim, Joon Bum Kim, Sung-Ho Jung, Suk Jung Choo, Cheol Hyun Chung, Jae Won Lee
Korean Circulation Journal.2021; 51(6): 504. CrossRef
Analysis of application of dental sedation in attention deficit hyperactivity disorder (ADHD) patients using the Korean National Health Insurance data
Seong In Chi, Hyuk Kim, Kwang-Suk Seo
Journal of Dental Anesthesia and Pain Medicine.2021; 21(2): 99. CrossRef
Deep Spinal Infection after Outpatient Epidural Injections for Pain: A Retrospective Sample Cohort Study Using a Claims Database in South Korea
Chang-Soon Lee, Young Jae Park, Jee Youn Moon, Yong-Chul Kim
Anesthesiology.2021; 134(6): 925. CrossRef
Obesity, metabolic health, and urological disorders in adults: a nationwide population-based study
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Pre-transplant Dementia is Associated with Poor Survival After Hematopoietic Stem Cell Transplantation: A Nationwide Cohort Study with Propensity Score Matched Control
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Clinical Psychopharmacology and Neuroscience.2021; 19(2): 294. CrossRef
Risks and Prognoses of Alzheimer's Disease and Vascular Dementia in Patients With Insomnia: A Nationwide Population-Based Study
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Frontiers in Neurology.2021;[Epub] CrossRef
The Association Between Second-Line Oral Antihyperglycemic Medication on Types of Dementia in Type 2 Diabetes: A Nationwide Real-World Longitudinal Study
Won Jun Kim, Jung Hyun Noh, Kyungdo Han, Cheol-Young Park
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Effect of Short-Term Exposure to Fine Particulate Matter and Temperature on Acute Myocardial Infarction in Korea
Jiyoung Shin, Jongmin Oh, In-Sook Kang, Eunhee Ha, Wook-Bum Pyun
International Journal of Environmental Research and Public Health.2021; 18(9): 4822. CrossRef
Incident Parkinson’s disease in kidney transplantation recipients: a nationwide population-based cohort study in Korea
Seon Ha Baek, Sehoon Park, Mi-yeon Yu, Ji Eun Kim, Sang Hyun Park, Kyungdo Han, Yong Chul Kim, Dong Ki Kim, Kwon Wook Joo, Yon Su Kim, Hajeong Lee
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Proteinuria and Psoriasis Risk: A Nationwide Population-Based Study
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Risk of COVID-19 and major adverse clinical outcomes among people with disabilities in South Korea
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Disability and Health Journal.2021; 14(4): 101127. CrossRef
Use of Proton Pump Inhibitors vs Histamine 2 Receptor Antagonists for the Risk of Gastric Cancer: Population-Based Cohort Study
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American Journal of Gastroenterology.2021; 116(6): 1211. CrossRef
Risk of upper gastrointestinal bleeding in patients on oral anticoagulant and proton pump inhibitor co-therapy
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Long-term mortality due to infection associated with elevated liver enzymes: a population-based cohort study
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Newly diagnosed diabetes has high risk for cardiovascular outcome in ischemic stroke patients
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Tooth loss is associated with an increased risk of hypertension: A nationwide population-based cohort study
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Anemia May Increase the Overall Risk of Cancer: Findings from a Cohort Study with a 12-Year Follow-up Period in South Korea
Tak Kyu Oh, In-Ae Song
Cancer Epidemiology, Biomarkers & Prevention.2021; 30(7): 1440. CrossRef
Association of mortality with drug-coated devices in femoropopliteal artery based on the nationwide data
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Annals of Surgical Treatment and Research.2021; 101(1): 20. CrossRef
Seasonal variation of patulous Eustachian tube diagnoses using climatic and national health insurance data
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The Journal of Laryngology & Otology.2021; 135(8): 695. CrossRef
Clinical Study Using Healthcare Claims Database
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Journal of Rheumatic Diseases.2021; 28(3): 119. CrossRef
History of anemia and long-term mortality due to infection: a cohort study with 12 years follow-up in South Korea
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BMC Infectious Diseases.2021;[Epub] CrossRef
Trends of age‐related non‐communicable diseases in people living with HIV and comparison with uninfected controls: A nationwide population‐based study in South Korea
Jung Ho Kim, Juhwan Noh, Woojin Kim, Hye Seong, Jun Hyoung Kim, Woon Ji Lee, YaeJee Baek, JongHoon Hyun, Yujin Sohn, Yunsuk Cho, Moo Hyun Kim, SangMin Ahn, Yongseop Lee, Jin Young Ahn, Su Jin Jeong, Nam Su Ku, Joon‐Sup Yeom, Changsoo Kim, Jun Yong Choi
HIV Medicine.2021; 22(9): 824. CrossRef
Risk of Heart Disease after Cholecystectomy: A Nationwide Population-Based Cohort Study in South Korea
Yoo Jin Kim, Young Soo Park, Cheol Min Shin, Kyungdo Han, Sang Hyun Park, Hyuk Yoon, Nayoung Kim, Dong Ho Lee
Journal of Clinical Medicine.2021; 10(15): 3253. CrossRef
Dose-Dependent Effect of Smoking on Risk of Diabetes Remains after Smoking Cessation: A Nationwide Population-Based Cohort Study in Korea
Se Eun Park, Mi Hae Seo, Jung-Hwan Cho, Hyemi Kwon, Yang-Hyun Kim, Kyung-Do Han, Jin-Hyung Jung, Yong-Gyu Park, Eun-Jung Rhee, Won-Young Lee
Diabetes & Metabolism Journal.2021; 45(4): 539. CrossRef
Automatic Classification of Thyroid Findings Using Static and Contextualized Ensemble Natural Language Processing Systems: Development Study
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JMIR Medical Informatics.2021; 9(9): e30223. CrossRef
Effect of Sedatives on In-hospital and Long-term Mortality of Critically Ill Patients Requiring Extended Mechanical Ventilation for ≥ 48 Hours
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Prior antiviral treatment and mortality among patients with hepatitis C virus-related hepatocellular carcinoma: A national cohort study
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Relationship between total cholesterol level and tuberculosis risk in a nationwide longitudinal cohort
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Scientific Reports.2021;[Epub] CrossRef
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Medicine.2021; 100(30): e26670. CrossRef
The Association between Peri-Transplant RBC Transfusion and Graft Failure after Kidney Transplantation: A Nationwide Cohort Study
Kyungho Lee, Seohee Lee, Eun Jin Jang, Ga Hee Kim, Seokha Yoo, Minkyoo Lee, Hye Ryoun Jang, Ho Geol Ryu
Journal of Clinical Medicine.2021; 10(16): 3750. CrossRef
Empathy With Patients and Post-Traumatic Stress Response in Verbally Abused Healthcare Workers
Soo-hyun Nam, Dong-Wook Lee, Hwa-yeon Seo, Yun-Chul Hong, Je-Yeon Yun, Sung-jun Cho, Nami Lee
Psychiatry Investigation.2021; 18(8): 770. CrossRef
Smoking cessation, but not reduction, reduces cardiovascular disease incidence
Su-Min Jeong, Keun Hye Jeon, Dong Wook Shin, Kyungdo Han, Dahye Kim, Sang Hyun Park, Mi Hee Cho, Cheol Min Lee, Ki-Woong Nam, Seung Pyo Lee
European Heart Journal.2021; 42(40): 4141. CrossRef
Does Exposure of Lead and Cadmium Affect the Endometriosis?
Min-Gi Kim, Young-Sun Min, Yeon-Soon Ahn
International Journal of Environmental Research and Public Health.2021; 18(17): 9077. CrossRef
Association of Periodontal Disease with the Occurrence of Unruptured Cerebral Aneurysm among Adults in Korea: A Nationwide Population-Based Cohort Study
Ho-Geol Woo, Yoon-Kyung Chang, Ji-Sung Lee, Tae-Jin Song
Medicina.2021; 57(9): 910. CrossRef
Synergistic harmful interaction between sustained physical inactivity and hypertension/diabetes mellitus on the risk of all-cause mortality: a retrospective observational cohort study
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Being Underweight Increases the Risk of Non-Cystic Fibrosis Bronchiectasis in the Young Population: A Nationwide Population-Based Study
Bumhee Yang, Kyungdo Han, Sang Hyuk Kim, Dong-Hwa Lee, Sang Hyun Park, Jung Eun Yoo, Dong Wook Shin, Hayoung Choi, Hyun Lee
Nutrients.2021; 13(9): 3206. CrossRef
Particular matter influences the incidence of acute otitis media in children
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Changes in the Prosthesis Types Used for Aortic Valve Replacement after the Introduction of Sutureless and Rapid Deployment Valves in Korea: A Nationwide Population-Based Cohort Study
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Association between haemorrhagic fever with renal syndrome and cancers
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International Journal of Infectious Diseases.2021; 113: 127. CrossRef
Blood Pressure and Cardiovascular Disease in Older Patients With Diabetes: Retrospective Cohort Study
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Journal of the American Heart Association.2021;[Epub] CrossRef
Relationship between blood pressure levels and ischemic stroke, myocardial infarction, and mortality in very elderly patients taking antihypertensives: a nationwide population-based cohort study
Myung-Sun Song, Yeon joo Choi, Hyunjin Kim, Myung Ji Nam, Chung-woo Lee, Kyungdo Han, Jin-Hyung Jung, Yong-Gyu Park, Do-Hoon Kim, Joo-Hyun Park
BMC Geriatrics.2021;[Epub] CrossRef
Effects of menopausal hormone therapy on cardiovascular diseases and type 2 diabetes in middle-aged postmenopausal women: analysis of the Korea National Health Insurance Service Database
Ji-Eun Kim, Jaesung Choi, JooYong Park, Aesun Shin, Nam-Kyong Choi, Ji-Yeob Choi
Menopause.2021; 28(11): 1225. CrossRef
Epidemiology of Achilles Tendon Rupture in South Korea: Claims Data of the National Health Insurance Service from 2009 to 2017
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Clinics in Orthopedic Surgery.2021; 13(4): 539. CrossRef
Comparison of risk profiles for new-onset atrial fibrillation between patients aged <60 and ≥60 years
In-Soo Kim, Yeon-Jik Choi, Eui-Young Choi, Pil-Ki Min, Young Won Yoon, Byoung Kwon Lee, Bum-Kee Hong, Se-Joong Rim, Hyuck Moon Kwon, Jong-Youn Kim, Luigi Sciarra
PLOS ONE.2021; 16(11): e0258770. CrossRef
Comparison of Risk of Pneumonia Caused by Fluticasone Propionate versus Budesonide in Chronic Obstructive Pulmonary Disease: A Nationwide Retrospective Cohort Study
Jae-Hwa Choi, Keun-Bae Jeong, You Hyun Park, Iseul Yu, Seok Jeong Lee, Myoung Kyu Lee, Sang-Ha Kim, Won-Yeon Lee, Suk Joong Yong, Ji-Ho Lee
International Journal of Chronic Obstructive Pulmonary Disease.2021; Volume 16: 3229. CrossRef
Clinical Impact of Hormone Replacement Therapy on Atrial Fibrillation in Postmenopausal Women: A Nationwide Cohort Study
Jaehoon Lee, Yuntae Kim, Hyunji Park, Changsoo Kim, Sihyun Cho, Jongyoun Kim
Journal of Clinical Medicine.2021; 10(23): 5497. CrossRef
Rheumatoid Arthritis in Silica-Exposed Workers
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International Journal of Environmental Research and Public Health.2021; 18(23): 12776. CrossRef
Changes in metabolic syndrome and risk of psoriasis: a nationwide population-based study
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Fasting Glucose Variability as a Risk Indicator for End-Stage Kidney Disease in Patients with Diabetes: A Nationwide Population-Based Study
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Journal of Clinical Medicine.2021; 10(24): 5948. CrossRef
Female Reproductive Factors and Risk of Bronchiectasis: A Nationwide Population-Based Longitudinal Study
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SSRN Electronic Journal .2021;[Epub] CrossRef
Associations of Systolic Blood Pressure With Incident CKD G3-G5: A Cohort Study of South Korean Adults
Tae Ik Chang, Hyunsun Lim, Cheol Ho Park, Connie M. Rhee, Hamid Moradi, Kamyar Kalantar-Zadeh, Ea Wha Kang, Shin-Wook Kang, Seung Hyeok Han
American Journal of Kidney Diseases.2020; 76(2): 224. CrossRef
Gamma-glutamyl transferase variability can predict the development of end-stage of renal disease: a nationwide population-based study
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Association of Tooth Loss with New-Onset Parkinson’s Disease: A Nationwide Population-Based Cohort Study
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Physical performance and chronic kidney disease development in elderly adults: results from a nationwide cohort study
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Aging.2020; 12(17): 17393. CrossRef
Association Between Income Disparities and Risk of Chronic Kidney Disease
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Mayo Clinic Proceedings.2020; 95(2): 231. CrossRef
Pre-transplant depression decreased overall survival of patients receiving allogeneic hematopoietic stem cell transplantation: a nationwide cohort study
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Label Adherence of Direct Oral Anticoagulants Dosing and Clinical Outcomes in Patients With Atrial Fibrillation
Hee Tae Yu, Pil‐Sung Yang, Eunsun Jang, Tae‐Hoon Kim, Jae‐Sun Uhm, Jong‐Youn Kim, Hui‐Nam Pak, Moon‐Hyoung Lee, Gregory Y. H. Lip, Boyoung Joung
Journal of the American Heart Association.2020;[Epub] CrossRef
Associations among Obesity Degree, Glycemic Status, and Risk of Heart Failure in 9,720,220 Korean Adults
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Diabetes & Metabolism Journal.2020; 44(4): 592. CrossRef
Obesity Fact Sheet in Korea, 2019: Prevalence of Obesity and Abdominal Obesity from 2009 to 2018 and Social Factors
Ga Eun Nam, Yang-Hyun Kim, Kyungdo Han, Jin-Hyung Jung, Eun-Jung Rhee, Seong-Su Lee, Dae Jung Kim, Kwan-Woo Lee, Won-Young Lee
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Safety of acupuncture during pregnancy: a retrospective cohort study in Korea
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BJOG: An International Journal of Obstetrics & Gynaecology.2020; 127(1): 79. CrossRef
Bell’s palsy and obesity, alcohol consumption and smoking: A nested case-control study using a national health screening cohort
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Da Young Lee, Kyungdo Han, Sanghyun Park, Ji Hee Yu, Ji A. Seo, Nam Hoon Kim, Hye Jin Yoo, Sin Gon Kim, Kyung Mook Choi, Sei Hyun Baik, Yong Gyu Park, Nan Hee Kim
Cardiovascular Diabetology.2020;[Epub] CrossRef
Changes in metabolic syndrome and its components and the risk of type 2 diabetes: a nationwide cohort study
Min-Kyung Lee, Kyungdo Han, Mee Kyoung Kim, Eun Sil Koh, Eun Sook Kim, Ga Eun Nam, Hyuk-Sang Kwon
Scientific Reports.2020;[Epub] CrossRef
Increased Cardiovascular Risk and All-cause Death in Patients with Behçet Disease: A Korean Nationwide Population-based Dynamic Cohort Study
Hyo-Suk Ahn, Dongjae Lee, Soo Young Lee, Yeong Ho Kim, Ji Hyun Lee, Dong Soo Yu, Kyung-Do Han, Yong Gyu Park, Young Bok Lee
The Journal of Rheumatology.2020; 47(6): 903. CrossRef
Gamma-Glutamyl Transferase Variability and Risk of Dementia in Diabetes Mellitus: A Nationwide Population-Based Study
So-hyeon Hong, Kyungdo Han, Sanghyun Park, Seon Mee Kim, Nan Hee Kim, Kyung Mook Choi, Sei Hyun Baik, Yong Gyu Park, Hye Jin Yoo
The Journal of Clinical Endocrinology & Metabolism.2020; 105(3): e119. CrossRef
Outcomes in relation to antithrombotic therapy among patients with atrial fibrillation after percutaneous coronary intervention
Jiesuck Park, Eue-Keun Choi, Kyung-Do Han, Bongseong Kim, You-Jung Choi, So-Ryoung Lee, Jeehoon Kang, Myung-Jin Cha, Kyung Woo Park, Seil Oh, Gregory Y. H. Lip, Chun Chieh Yeh
PLOS ONE.2020; 15(10): e0240161. CrossRef
Smoking and Alcohol Consumption Are Associated With the Increased Risk of Peritonsillar Abscess
So Young Kim, Hyoseob Lim, Hyo Geun Choi
The Laryngoscope.2020; 130(12): 2833. CrossRef
The Population Prevalence, Associations of Congenital Heart Defect and Mortality Risk for Down’s Syndrome in South Korea Based on National Health Insurance Service (NHIS) Data

Won Kyoung Cho, Na Young Lee, Kyungdo Han, Byung-Kyu Suh, Yong-Gyu Park
Clinical Epidemiology.2020; Volume 12: 519. CrossRef
Prognostic value of long-term gamma-glutamyl transferase variability in individuals with diabetes: a nationwide population-based study
Da Young Lee, Kyungdo Han, Ji Hee Yu, Sanghyun Park, Ji A Seo, Nam Hoon Kim, Hye Jin Yoo, Sin Gon Kim, Seon Mee Kim, Kyung Mook Choi, Sei Hyun Baik, Yong Gyu Park, Nan Hee Kim
Scientific Reports.2020;[Epub] CrossRef
Trends and risk factors of elderly-onset Crohn’s disease: A nationwide cohort study
Jung Min Moon, Eun Ae Kang, Kyungdo Han, Seung Wook Hong, Hosim Soh, Seona Park, Jooyoung Lee, Hyun Jung Lee, Jong Pil Im, Joo Sung Kim
World Journal of Gastroenterology.2020; 26(4): 404. CrossRef
Improved oral hygiene is associated with decreased risk of new-onset diabetes: a nationwide population-based cohort study
Yoonkyung Chang, Ji Sung Lee, Ki-Jung Lee, Ho Geol Woo, Tae-Jin Song
Diabetologia.2020; 63(5): 924. CrossRef
Development of stroke identification algorithm for claims data using the multicenter stroke registry database
Jun Yup Kim, Keon-Joo Lee, Jihoon Kang, Beom Joon Kim, Moon-Ku Han, Seong-Eun Kim, Heeyoung Lee, Jong-Moo Park, Kyusik Kang, Soo Joo Lee, Jae Guk Kim, Jae-Kwan Cha, Dae-Hyun Kim, Tai Hwan Park, Moo-Seok Park, Sang-Soon Park, Kyung Bok Lee, Hong-Kyun Park,
PLOS ONE.2020; 15(2): e0228997. CrossRef
Cardiovascular Research Using the Korean National Health Information Database
Eue-Keun Choi
Korean Circulation Journal.2020; 50(9): 754. CrossRef
Impact of the timing of Helicobacter pylori eradication on the risk of development of metachronous lesions after treatment of early gastric cancer: a population-based cohort study
Hyun Ju Kim, Yun Jin Kim, Seung In Seo, Woon Geon Shin, Chan Hyuk Park
Gastrointestinal Endoscopy.2020; 92(3): 613. CrossRef
Bodyweight fluctuation is associated with increased risk of incident atrial fibrillation
Hyun-Jung Lee, Eue-Keun Choi, Kyung-Do Han, Euijae Lee, Inki Moon, So-Ryoung Lee, Myung-Jin Cha, Seil Oh, Gregory Y.H. Lip
Heart Rhythm.2020; 17(3): 365. CrossRef
Longitudinal Study of Diabetic Differences between International Migrants and Natives among the Asian Population
Heng Piao, Jae Moon Yun, Aesun Shin, Belong Cho
Biomolecules & Therapeutics.2020; 28(1): 110. CrossRef
Early detection of influenza outbreak using time derivative of incidence
Woo-Sik Son, Ji-Eun Park, Okyu Kwon
EPJ Data Science.2020;[Epub] CrossRef
A prediction model of low back pain risk: a population based cohort study in Korea
David Mukasa, Joohon Sung
The Korean Journal of Pain.2020; 33(2): 153. CrossRef
The impact of PM2.5 on acute otitis media in children (aged 0–3): A time series study
Jongmin Oh, Seulbi Lee, Min-ho Kim, Youngrin Kwag, Hae Soon Kim, Soontae Kim, Shinhee Ye, Eunhee Ha
Environment International.2020; 145: 106133. CrossRef
Serum gamma-glutamyltransferase activity and Parkinson’s disease risk in men and women
Dallah Yoo, Ryul Kim, Yu Jin Jung, Kyungdo Han, Cheol Min Shin, Jee-Young Lee
Scientific Reports.2020;[Epub] CrossRef
Association between institutional case volume and mortality following thoracic aorta replacement: a nationwide Korean cohort study
Karam Nam, Eun Jin Jang, Jun Woo Jo, Jae Woong Choi, Minkyoo Lee, Ho Geol Ryu
Journal of Cardiothoracic Surgery.2020;[Epub] CrossRef
Underutilization of Hospital-based Cardiac Rehabilitation after Acute Myocardial Infarction in Korea
Sun-Hyung Kim, Jun-soo Ro, Yoon Kim, Ja-Ho Leigh, Won-Seok Kim
Journal of Korean Medical Science.2020;[Epub] CrossRef
Infection, antibiotic exposure and development of atopic dermatitis: A nationwide case–control study
Chong Won Choi, Bo Ram Yang, Dong In Suh, Mi‐Sook Kim, Jungyoon Ohn, Jong Soo Hong, Joongyub Lee, Kyu Han Kim
The Journal of Dermatology.2020; 47(7): 707. CrossRef
Effect of the variability of blood pressure, glucose level, total cholesterol level, and body mass index on the risk of atrial fibrillation in a healthy population
So-Ryoung Lee, Eue-Keun Choi, Kyung-Do Han, Seung-Hwan Lee, Seil Oh
Heart Rhythm.2020; 17(1): 12. CrossRef
Impact of Mitral Valve Repair Case Volume on Postoperative Mortality　― A Nationwide Korean Cohort Study ―
Karam Nam, Eun Jin Jang, Jun Woo Jo, Jae Woong Choi, Jun Gi Jo, Jaehun Lee, Ho Geol Ryu
Circulation Journal.2020; 84(9): 1493. CrossRef
The Clinical Impact of Body Mass Index on Breast Cancer in Korea: A Nationwide Population-Based Cohort Study
Jae Hwan Jeong, Hak Min Lee, Hai Young Son, Ilkyun Lee
Journal of Breast Disease.2020; 8(1): 51. CrossRef
Improved oral hygiene care is associated with decreased risk of occurrence for atrial fibrillation and heart failure: A nationwide population-based cohort study
Yoonkyung Chang, Ho Geol Woo, Jin Park, Ji Sung Lee, Tae-Jin Song
European Journal of Preventive Cardiology.2020; 27(17): 1835. CrossRef
Increased Mortality Burden in Young Asian Subjects with Dysglycemia and Comorbidities
Eun-Jung Rhee, Inha Jung, Hyemi Kwon, Se Eun Park, Yang-Hyun Kim, Kyung-Do Han, Yong-Gyu Park, Won-Young Lee
Journal of Clinical Medicine.2020; 9(4): 1042. CrossRef
Fasting Plasma Glucose Variability and Gastric Cancer Risk in Individuals Without Diabetes Mellitus: A Nationwide Population-Based Cohort Study
So-hyeon Hong, Eunjin Noh, Jinsil Kim, Soon Young Hwang, Jun A. Kim, You-Bin Lee, Eun Roh, Kyung Mook Choi, Sei Hyun Baik, Geum Joon Cho, Hye Jin Yoo
Clinical and Translational Gastroenterology.2020; 11(9): e00221. CrossRef
Use of Gadoxetic Acid–enhanced Liver MRI and Mortality in More than 30 000 Patients with Hepatocellular Carcinoma: A Nationwide Analysis
Tae Wook Kang, Sun-Young Kong, Danbee Kang, Min Woong Kang, Young Kon Kim, Seong Hyun Kim, Dong Hyun Sinn, Young Ae Kim, Kui Son Choi, Eun Sook Lee, Sang Myung Woo, Joung Hwan Back, Eliseo Guallar, Juhee Cho
Radiology.2020; 295(1): 114. CrossRef
The association between sialolithiasis and smoking, alcohol drinking and obesity in Korea: a nested case-control study
Young Ju Jin, Young Eun Han, Hyo Geun Choi
BMC Public Health.2020;[Epub] CrossRef
Outcomes for Inappropriate Renal Dose Adjustment of Dipeptidyl Peptidase-4 Inhibitors in Patients With Type 2 Diabetes Mellitus: Population-Based Study
Sangmo Hong, Kyungdo Han, Cheol-Young Park
Mayo Clinic Proceedings.2020; 95(1): 101. CrossRef
Impact of Mean and Variability of High‐Density Lipoprotein‐Cholesterol on the Risk of Myocardial Infarction, Stroke, and Mortality in the General Population
Byung‐Hun Han, Kyungdo Han, Kun‐Ho Yoon, Mee Kyoung Kim, Seung‐Hwan Lee
Journal of the American Heart Association.2020;[Epub] CrossRef
Underweight Increases the Risk of End-Stage Renal Diseases for Type 2 Diabetes in Korean Population: Data From the National Health Insurance Service Health Checkups 2009–2017
Yang-Hyun Kim, Jun Goo Kang, Seong Jin Lee, Kyung-do Han, Sung-Hee Ihm, Kyung-Hwan Cho, Yong-Gyu Park
Diabetes Care.2020; 43(5): 1118. CrossRef
Pneumonia risk and its associated factors in Parkinson's disease: A National Database Study
Jun Hee Won, Seong Jun Byun, Byung-Mo Oh, Han-Joon Kim, Sang Jun Park, Han Gil Seo
Journal of the Neurological Sciences.2020; 415: 116949. CrossRef
The Association with rhegmatogenous retinal detachment and paediatric atopic dermatitis: a 12-year Nationwide Cohort Study
M. Choi, S. J. Byun, D. H. Lee, K. H. Kim, K. H. Park, S. J. Park
Eye.2020; 34(10): 1909. CrossRef
Peripartum Blood Transfusions are Associated with Increased Risk of Cancer: A National Retrospective Cohort Study

Geum Joon Cho, Michael S Oh, Min-Jeong Oh, Keon Vin Park, Sung Won Han, Young Kwang Chae
Clinical Epidemiology.2020; Volume 12: 659. CrossRef
The Burden of Cervical Cancer in Korea: A Population-Based Study
Jinhee Kim, Donghwan Lee, Kyung-Bok Son, SeungJin Bae
International Journal of Environmental Research and Public Health.2020; 17(17): 6308. CrossRef
Temporal trends of catheter ablation for patients with atrial fibrillation: A Korean nationwide population‐based study
Euijae Lee, So‐Ryoung Lee, Eue‐Keun Choi, Kyung‐Do Han, Myung‐Jin Cha, Gregory Y.H. Lip, Seil Oh
Journal of Cardiovascular Electrophysiology.2020; 31(10): 2616. CrossRef
Trend of prevalence and incidence of systemic lupus erythematosus in South Korea, 2005 to 2015: a nationwide population-based study
Eun Hui Bae, Sang Yeob Lim, Kyung-Do Han, Jin-Hyung Jung, Hong Sang Choi, Ha Yeon Kim, Chang Seong Kim, Seong Kwon Ma, Soo Wan Kim
The Korean Journal of Internal Medicine.2020; 35(3): 652. CrossRef
Achievement of the low-density lipoprotein cholesterol goal among patients with dyslipidemia in South Korea
Siin Kim, Sola Han, Pratik P. Rane, Yi Qian, Zhongyun Zhao, Hae Sun Suh, Luigina Guasti
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Oral health and gastrointestinal cancer: A nationwide cohort study
Kijeong Lee, Ji Sung Lee, Jinkwon Kim, Huisong Lee, Yoonkyung Chang, Ho Geol Woo, Jin‐Woo Kim, Tae‐Jin Song
Journal of Clinical Periodontology.2020; 47(7): 796. CrossRef
Site-specific cancer risk in patients with type 2 diabetes: a nationwide population-based cohort study in Korea
Suk Kyeong Kim, Ju-Young Jang, Dong-Lim Kim, Young A Rhyu, Suh Eun Lee, Seung-Hyun Ko, Kyungdo Han, Kee-Ho Song
The Korean Journal of Internal Medicine.2020; 35(3): 641. CrossRef
Data Configuration and Publication Trends for the Korean National Health Insurance and Health Insurance Review & Assessment Database
Hae Kyung Kim, Sun Ok Song, Junghyun Noh, In-Kyung Jeong, Byung-Wan Lee
Diabetes & Metabolism Journal.2020; 44(5): 671. CrossRef
Metformin and Gastrointestinal Cancer Development in Newly Diagnosed Type 2 Diabetes: A Population-Based Study in Korea
Ji Hong You, Sun Ok Song, Min Jin Kang, Yoon Young Cho, Sun Wook Kim, Sung Hwan Suh, Sujin Lee, Yong-ho Lee, Byung-Wan Lee
Clinical and Translational Gastroenterology.2020; 11(11): e00254. CrossRef
Machine learning prediction for mortality of patients diagnosed with COVID-19: a nationwide Korean cohort study
Chansik An, Hyunsun Lim, Dong-Wook Kim, Jung Hyun Chang, Yoon Jung Choi, Seong Woo Kim
Scientific Reports.2020;[Epub] CrossRef
The association between hospital case volume and in-hospital and one-year mortality after hip fracture surgery
Seokha Yoo, Eun Jin Jang, Junwoo Jo, Jun Gi Jo, Seungpyo Nam, Hansol Kim, Hannah Lee, Ho Geol Ryu
The Bone & Joint Journal.2020; 102-B(10): 1384. CrossRef
Association between physical activity and conversion from mild cognitive impairment to dementia
Yeo Jin Kim, Kyung-Do Han, Min Seok Baek, Hanna Cho, Eun Joo Lee, Chul Hyoung Lyoo
Alzheimer's Research & Therapy.2020;[Epub] CrossRef
Clinical Outcomes of COVID-19 Patients with Type 2 Diabetes: A Population-Based Study in Korea
Ji Hong You, Sang Ah Lee, Sung-Youn Chun, Sun Ok Song, Byung-Wan Lee, Dae Jung Kim, Edward J. Boyko
Endocrinology and Metabolism.2020; 35(4): 901. CrossRef
Does Diabetes Increase the Risk of Contracting COVID-19? A Population-Based Study in Korea
Sung-Youn Chun, Dong Wook Kim, Sang Ah Lee, Su Jung Lee, Jung Hyun Chang, Yoon Jung Choi, Seong Woo Kim, Sun Ok Song
Diabetes & Metabolism Journal.2020; 44(6): 897. CrossRef
The triglyceride glucose index is a simple and low-cost marker associated with atherosclerotic cardiovascular disease: a population-based study
Sangmo Hong, Kyungdo Han, Cheol-Young Park
BMC Medicine.2020;[Epub] CrossRef
The durability and effectiveness of sensor-augmented insulin pump therapy in pediatric and young adult patients with type 1 diabetes
Yun Jeong Lee, Young Ah Lee, Jae Hyun Kim, Hye Rim Chung, Min Jeong Gu, Ji Young Kim, Choong Ho Shin
Annals of Pediatric Endocrinology & Metabolism.2020; 25(4): 248. CrossRef
Impact of comorbid asthma on severity of coronavirus disease (COVID-19)
Sang Chul Lee, Kang Ju Son, Chang Hoon Han, Ji Ye Jung, Seon Cheol Park
Scientific Reports.2020;[Epub] CrossRef
Big Data in Ophthalmology
Ching-Yu Cheng, Zhi Da Soh, Shivani Majithia, Sahil Thakur, Tyler Hyungtaek Rim, Yih Chung Tham, Tien Yin Wong
Asia-Pacific Journal of Ophthalmology.2020; 9(4): 291. CrossRef
Maintenance of body weight is an important determinant for the risk of ischemic stroke: A nationwide population-based cohort study
Jung-Hwan Cho, Eun-Jung Rhee, Se Eun Park, Hyemi Kwon, Jin-Hyung Jung, Kyung-Do Han, Yong-Gyu Park, Soon-Jib Yoo, Yang-Hyun Kim, Won-Young Lee, Sabine Rohrmann
PLOS ONE.2019; 14(1): e0210153. CrossRef
Effect of Institutional Case Volume on In-Hospital and Long-Term Mortality in Critically Ill Patients Requiring Mechanical Ventilation for 48 Hours or More
Hannah Lee, Seongmi Choi, Eun Jin Jang, Juhee Lee, Dalho Kim, Seokha Yoo, Seung Young Oh, Ho Geol Ryu
Journal of Korean Medical Science.2019;[Epub] CrossRef
Impact of the 2015 Middle East Respiratory Syndrome Outbreak on Emergency Care Utilization and Mortality in South Korea
Sun Young Lee, Young-Ho Khang, Hwa-Kyung Lim
Yonsei Medical Journal.2019; 60(8): 796. CrossRef
Effect of Institutional Case Volume on In-hospital Mortality After Living Donor Liver Transplantation: Analysis of 7073 Cases Between 2007 and 2016 in Korea
Seokha Yoo, Eun Jin Jang, Nam-Joon Yi, Ga Hee Kim, Dal Ho Kim, Hannah Lee, Chul-Woo Jung, Ho Geol Ryu
Transplantation.2019; 103(5): 952. CrossRef
Increased risk of benign paroxysmal positional vertigo in osteoporosis: a nationwide population-based cohort study
Hayoung Byun, Jae Ho Chung, Seung Hwan Lee, Chul Won Park, Eun Mi Kim, Inah Kim
Scientific Reports.2019;[Epub] CrossRef
Incremental economic burden associated with exudative age-related macular degeneration: a population-based study
Siin Kim, Sang Jun Park, Seong Jun Byun, Kyu Hyung Park, Hae Sun Suh
BMC Health Services Research.2019;[Epub] CrossRef
Patients with Inflammatory Bowel Disease Are at an Increased Risk of Parkinson’s Disease: A South Korean Nationwide Population-Based Study
Seona Park, Jihye Kim, Jaeyoung Chun, Kyungdo Han, Hosim Soh, Eun Ae Kang, Hyun Jung Lee, Jong Pil Im, Joo Sung Kim
Journal of Clinical Medicine.2019; 8(8): 1191. CrossRef
Effect of hypertension duration and blood pressure level on ischaemic stroke risk in atrial fibrillation: nationwide data covering the entire Korean population
Tae-Hoon Kim, Pil-Sung Yang, Hee Tae Yu, Eunsun Jang, Hyejung Shin, Ha Yan Kim, Jae-Sun Uhm, Jong-Youn Kim, Jung-Hoon Sung, Hui-Nam Pak, Moon-Hyoung Lee, Boyoung Joung, Gregory Y H Lip
European Heart Journal.2019; 40(10): 809. CrossRef
Perioperative red blood cell transfusion and mortality following heart transplantation: A retrospective nationwide population‐based study between 2007 and 2016 in Korea
Karam Nam, Eun Jin Jang, Ga Hee Kim, Hyung Been Yhim, Hannah Lee, Dal Ho Kim, Ho Geol Ryu
Journal of Cardiac Surgery.2019; 34(10): 927. CrossRef
The Effect of Health-Related Behaviors on Disease Progression and Mortality in Early Stages of Chronic Kidney Disease: A Korean Nationwide Population-Based Study
Yookyung Lee, SuYeon Kwon, Jong Joo Moon, Kyungdo Han, Nam-Jong Paik, Won-Seok Kim
Journal of Clinical Medicine.2019; 8(8): 1100. CrossRef
Association of body mass index with bladder cancer risk in men depends on abdominal obesity
Jin Bong Choi, Jung Ho Kim, Sung-Hoo Hong, Kyung-Do Han, U-Syn Ha
World Journal of Urology.2019; 37(11): 2393. CrossRef
Time‐ and Dose‐Dependent Association of Statin Use With Risk of Clinically Relevant New‐Onset Diabetes Mellitus in Primary Prevention: A Nationwide Observational Cohort Study
Min Jung Ko, Ae Jeong Jo, Yun Jung Kim, Shin Hee Kang, Songhee Cho, Sang‐Ho Jo, Cheol‐Young Park, Sung‐Cheol Yun, Woo Je Lee, Duk‐Woo Park
Journal of the American Heart Association.2019;[Epub] CrossRef
Association of Long-term Use of Low-Dose Aspirin as Chemoprevention With Risk of Lung Cancer
Shinhee Ye, Myeongjee Lee, Dongheon Lee, Eun-Hee Ha, Eun Mi Chun
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Association between BMI and risk of severe hypoglycaemia in type 2 diabetes
J.-S. Yun, Y.-M. Park, K. Han, S.-A. Cha, Y.-B. Ahn, S.-H. Ko
Diabetes & Metabolism.2019; 45(1): 19. CrossRef
Risk of Incident Dementia According to Metabolic Health and Obesity Status in Late Life: A Population-Based Cohort Study
Ji-Yeon Lee, Kyungdo Han, Eugene Han, Gyuri Kim, Hanna Cho, Kwang Joon Kim, Byung Wan Lee, Eun Seok Kang, Bong-Soo Cha, Carol Brayne, Yong-ho Lee
The Journal of Clinical Endocrinology & Metabolism.2019; 104(7): 2942. CrossRef
Increased Risk of Osteoporotic Fracture in Postgastrectomy Gastric Cancer Survivors Compared With Matched Controls: A Nationwide Cohort Study in Korea
Dong Wook Shin, Beomseok Suh, Hyunsun Lim, Yun-Suhk Suh, Yoon Jin Choi, Su-Min Jeong, Jae Moon Yun, Sun Ok Song, Youngmin Park
American Journal of Gastroenterology.2019; 114(11): 1735. CrossRef
Metabolic syndrome is associated with an increased risk of psoriasis: A nationwide population-based study
Ha-Na Kim, Kyungdo Han, Yong-Gyu Park, Ji Hyun Lee
Metabolism.2019; 99: 19. CrossRef
Association of Exposure to Diagnostic Low-Dose Ionizing Radiation With Risk of Cancer Among Youths in South Korea
Jae-Young Hong, Kyungdo Han, Jin-Hyung Jung, Jung Sun Kim
JAMA Network Open.2019; 2(9): e1910584. CrossRef
Long‐term clinical outcomes in patients with autoimmune hepatitis according to treatment response in Asian country
Jonggi Choi, Gwang Hyeon Choi, Danbi Lee, Ju Hyun Shim, Young‐Suk Lim, Han Chu Lee, Young‐Hwa Chung, Yung‐Sang Lee, Kang Mo Kim
Liver International.2019; 39(5): 985. CrossRef
Effectiveness and Safety of Direct Oral Anticoagulant for Secondary Prevention in Asians with Atrial Fibrillation
Jiesuck Park, So-Ryoung Lee, Eue-Keun Choi, Soonil Kwon, Jin-Hyung Jung, Kyung-Do Han, Myung-Jin Cha, Sang-Bae Ko, Seil Oh, Gregory Y. H. Lip
Journal of Clinical Medicine.2019; 8(12): 2228. CrossRef
Optimal Rivaroxaban Dose in Asian Patients With Atrial Fibrillation and Normal or Mildly Impaired Renal Function
So-Ryoung Lee, Eue-Keun Choi, Kyung-Do Han, Jin-Hyung Jung, Seil Oh, Gregory Y.H. Lip
Stroke.2019; 50(5): 1140. CrossRef
Tobacco Smoking and Alcohol Consumption Are Related to Benign Parotid Tumor: A Nested Case-Control Study Using a National Health Screening Cohort
So Young Kim, Chanyang Min, Dong Jun Oh, Hyo Geun Choi
Clinical and Experimental Otorhinolaryngology.2019; 12(4): 412. CrossRef
Increased Risk of Diabetes in Inflammatory Bowel Disease Patients: A Nationwide Population-Based Study in Korea
Eun Ae Kang, Kyungdo Han, Jaeyoung Chun, Hosim Soh, Seona Park, Jong Pil Im, Joo Sung Kim
Journal of Clinical Medicine.2019; 8(3): 343. CrossRef
Changes in the Diagnostic Efficiency of Thyroid Fine-Needle Aspiration Biopsy during the Era of Increased Thyroid Cancer Screening in Korea
Young Ki Lee, Kyeong Hye Park, Young Duk Song, Taemi Youk, Joo Young Nam, Sun Ok Song, Dong Yeob Shin, Eun Jig Lee
Cancer Research and Treatment.2019; 51(4): 1430. CrossRef
Safety and Effectiveness of Contemporary P2Y 12 Inhibitors in an East Asian Population With Acute Coronary Syndrome: A Nationwide Population‐Based Cohort Study
Ji Eun Yun, Yun Jung Kim, Ji Jeong Park, Sehee Kim, Keunhui Park, Min Soo Cho, Gi‐Byoung Nam, Duk‐Woo Park
Journal of the American Heart Association.2019;[Epub] CrossRef
Direct Oral Anticoagulants in Patients With Nonvalvular Atrial Fibrillation and Low Body Weight
So-Ryoung Lee, Eue-Keun Choi, Chan Soon Park, Kyung-Do Han, Jin-Hyung Jung, Seil Oh, Gregory Y.H. Lip
Journal of the American College of Cardiology.2019; 73(8): 919. CrossRef
Trends in varicella and herpes zoster epidemiology before and after the implementation of universal one-dose varicella vaccination over one decade in South Korea, 2003–2015
Jae-Ki Choi, Sun Hee Park, Sanghyun Park, Su-Mi Choi, Si-Hyun Kim, Dong-Gun Lee, Jin-Hong Yoo, Jung-Hyun Choi, Jin Han Kang
Human Vaccines & Immunotherapeutics.2019; 15(11): 2554. CrossRef
Obesity Fact Sheet in Korea, 2018: Data Focusing on Waist Circumference and Obesity-Related Comorbidities
Ga Eun Nam, Yang-Hyun Kim, Kyungdo Han, Jin-Hyung Jung, Yong Gyu Park, Kwan-Woo Lee, Eun-Jung Rhee, Jang Won Son, Seong-Su Lee, Hyuk-Sang Kwon, Won-Young Lee, Soon Jib Yoo
Journal of Obesity & Metabolic Syndrome.2019; 28(4): 236. CrossRef
Long-Term Impact of Newly Diagnosed Atrial Fibrillation During Critical Care
Kyu Kim, Pil-Sung Yang, Eunsun Jang, Hee Tae Yu, Tae-Hoon Kim, Jae-Sun Uhm, Jong-Youn Kim, Jung-Hoon Sung, Hui-Nam Pak, Moon-Hyoung Lee, Gregory Y.H. Lip, Boyoung Joung
Chest.2019; 156(3): 518. CrossRef
Correlation of Androgen Deprivation Therapy with Cognitive Dysfunction in Patients with Prostate Cancer: A Nationwide Population-Based Study Using the National Health Insurance Service Database
Bum Sik Tae, Byung Jo Jeon, Seung Hun Shin, Hoon Choi, Jae Hyun Bae, Jae Young Park
Cancer Research and Treatment.2019; 51(2): 593. CrossRef
Non-Vitamin K Antagonist Oral Anticoagulants in Patients with Atrial Fibrillation and Valvular Heart Disease
Inki Moon, So-Ryoung Lee, Eue-Keun Choi, Euijae Lee, Jin-Hyung Jung, Kyung-Do Han, Myung-Jin Cha, Seil Oh, Gregory Y.H. Lip
Journal of Clinical Medicine.2019; 8(10): 1624. CrossRef
Relation between Baseline Height and New Diabetes Development: A Nationwide Population-Based Study
Eun-Jung Rhee, Jung-Hwan Cho, Hyemi Kwon, Se-Eun Park, Jin-Hyung Jung, Kyung-Do Han, Yong-Gyu Park, Yang-Hyun Kim, Won-Young Lee
Diabetes & Metabolism Journal.2019; 43(6): 794. CrossRef
The Risk of Myocardial Infarction and Ischemic Stroke According to Waist Circumference in 21,749,261 Korean Adults: A Nationwide Population-Based Study
Jung-Hwan Cho, Eun-Jung Rhee, Se-Eun Park, Hyemi Kwon, Jin-Hyung Jung, Kyung-Do Han, Yong-Gyu Park, Hye Soon Park, Yang-Hyun Kim, Soon-Jib Yoo, Won-Young Lee
Diabetes & Metabolism Journal.2019; 43(2): 206. CrossRef
The risk of end-stage renal disease in systemic lupus erythematosus
Hong Sang Choi, Kyung-Do Han, Jin-Hyung Jung, Chang Seong Kim, Eun Hui Bae, Seong Kwon Ma, Soo Wan Kim
Medicine.2019; 98(28): e16420. CrossRef
Antithrombotic Therapy in Patients With Atrial Fibrillation After Percutaneous Coronary Intervention During 2-Year Follow-Up, from a Nationwide Population Study
Jiesuck Park, Eue-Keun Choi, Kyung-Do Han, You-Jung Choi, So-Ryoung Lee, Myung-Jin Cha, Jeehoon Kang, Kyung Woo Park, Seil Oh, Gregory Y.H. Lip
The American Journal of Cardiology.2019; 123(12): 1921. CrossRef
Outcomes After Use of Standard- and Low-Dose Non–Vitamin K Oral Anticoagulants in Asian Patients With Atrial Fibrillation
Min Soo Cho, Ji Eun Yun, Ji Jeong Park, Yun Jung Kim, Jessie Lee, Hyungmin Kim, Duk-Woo Park, Gi-Byoung Nam
Stroke.2019; 50(1): 110. CrossRef
Association between Atrial Fibrillation, Myocardial Infarction, Heart Failure and Mortality in Patients with Nontuberculous Mycobacterial Infection: a nationwide population-based study
Chan Soon Park, Eue-Keun Choi, Bongseong Kim, Kyung-Do Han, So-Ryoung Lee, Myung-Jin Cha, Seil Oh
Scientific Reports.2019;[Epub] CrossRef
National practice patterns and direct medical costs for prostate cancer in Korea across a 10 year period: a nationwide population-based study using a national health insurance database
Ho Won Kang, Seok-Joong Yun, Jae Il Chung, Hoon Choi, Jae Heon Kim, Ho Song Yu, Yun-Sok Ha, In-Chang Cho, Hyung Joon Kim, Hyun Chul Chung, Jun Sung Koh, Wun-Jae Kim, Jong-Hyock Park, Ji Youl Lee, So-Young Kim
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Institutional Case-Volume and Mortality After Heart Transplantation
Karam Nam, Eun Jin Jang, Ga Hee Kim, Hannah Lee, Dal Ho Kim, Ho Geol Ryu
International Heart Journal.2019; 60(3): 695. CrossRef
Weight change is significantly associated with risk of thyroid cancer: A nationwide population-based cohort study
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Scientific Reports.2019;[Epub] CrossRef
Venous thromboembolism in relapsed or refractory multiple myeloma patients treated with lenalidomide plus dexamethasone
Junghoon Shin, Je-Jung Lee, Kihyun Kim, Chang-Ki Min, Jeong-Ok Lee, Cheolwon Suh, Jin Seok Kim, Yoo Jin Lee, Sung-Soo Yoon, Jae-Cheol Jo, Ho Sup Lee, Soo-Mee Bang
International Journal of Hematology.2019; 109(1): 79. CrossRef
Actinic keratosis and diabetes complications: A nationwide population-based study in South Korea (2009–2015)
YoungBok Lee, JiHyun Lee, JinYoung Choi, DongSoo Yu, KyungDo Han, Yong-Gyu Park
Diabetes & Metabolism.2019; 45(1): 32. CrossRef
Ankylosing spondylitis: A novel risk factor for atrial fibrillation — A nationwide population-based study
Inki Moon, Eue-Keun Choi, Jin-Hyung Jung, Kyung-Do Han, You-Jung Choi, Jiesuck Park, Jun Hwan Cho, Euijae Lee, Wonseok Choe, So-Ryoung Lee, Myung-Jin Cha, Woo-Hyun Lim, Seil Oh
International Journal of Cardiology.2019; 275: 77. CrossRef
Cancer risk among young men with weight gain after smoking cessation: A population-based cohort study
Kyuwoong Kim, Seulggie Choi, Gyeongsil Lee, Su-Min Jeong, Sung Min Kim, Joung Sik Son, Jae-Moon Yun, Yeon-Yong Kim, Seong Yong Park, Sang Min Park
Cancer Epidemiology.2019; 60: 86. CrossRef
Effect of drug compliance on health care costs in newly-diagnosed dementia: Analysis of nationwide population-based data
Seung-Taek Oh, Kyu-Tae Han, Won-Jung Choi, Jaesub Park
Journal of Psychiatric Research.2019; 118: 31. CrossRef
Colorectal Cancer Risks According to Sex Differences in Patients With Type II Diabetes Mellitus: A Korean Nationwide Population-Based Cohort Study
Ji Min Lee, Kang-Moon Lee, Dae Bum Kim, Seung-Hyun Ko, Yong Gyu Park
Clinical and Translational Gastroenterology.2019; 10(10): e00090. CrossRef
Body Mass Index Variability and Long-term Risk of New-Onset Atrial Fibrillation in the General Population: A Korean Nationwide Cohort Study
Yeong-Min Lim, Pil-Sung Yang, Eunsun Jang, Hee Tae Yu, Tae-Hoon Kim, Jae-Sun Uhm, Jong-Youn Kim, Hui-Nam Pak, Moon-Hyoung Lee, Boyoung Joung, Gregory Y.H. Lip
Mayo Clinic Proceedings.2019; 94(2): 225. CrossRef
Childbirth in young Korean women with previously treated breast cancer: The SMARTSHIP study
Hak Min Lee, Bo Wook Kim, Seho Park, Sungmin Park, Jeon Eon Lee, Young Jin Choi, Sung Yong Kim, Sang Uk Woo, Hyun Jo Youn, Ilkyun Lee
Breast Cancer Research and Treatment.2019; 176(2): 419. CrossRef
Obstructive sleep apnea as a risk factor for incident end stage renal disease: a nationwide population-based cohort study from Korea
Hong Sang Choi, Ha Yeon Kim, Kyung-Do Han, Jin-Hyung Jung, Chang Seong Kim, Eun Hui Bae, Seong Kwon Ma, Soo Wan Kim
Clinical and Experimental Nephrology.2019; 23(12): 1391. CrossRef
Severe hypoglycemia and the risk of cardiovascular disease and mortality in type 2 diabetes: a nationwide population-based cohort study
Jae-Seung Yun, Yong-Moon Park, Kyungdo Han, Seon-Ah Cha, Yu-Bae Ahn, Seung-Hyun Ko
Cardiovascular Diabetology.2019;[Epub] CrossRef
Severity of dental caries and risk of coronary heart disease in middle-aged men and women: a population-based cohort study of Korean adults, 2002–2013
Kyuwoong Kim, Seulggie Choi, Jooyoung Chang, Sung Min Kim, Seon Jip Kim, Ryan Jin-Young Kim, Hyun-Jae Cho, Sang Min Park
Scientific Reports.2019;[Epub] CrossRef
Risk of Anxiety and Depression in Patients with Inflammatory Bowel Disease: A Nationwide, Population-Based Study
Kookhwan Choi, Jaeyoung Chun, Kyungdo Han, Seona Park, Hosim Soh, Jihye Kim, Jooyoung Lee, Hyun Lee, Jong Im, Joo Kim
Journal of Clinical Medicine.2019; 8(5): 654. CrossRef
The Effects after Implementing a Drug Utilization Review System on Contraindicated Drug use: A Systematic Review
Heeyoung Lee, Hyea Suk Choi, Eunhee Ji
Korean Journal of Clinical Pharmacy.2019; 29(1): 9. CrossRef
Nationwide Trends in Pancreatitis and Pancreatic Cancer Risk Among Patients With Newly Diagnosed Type 2 Diabetes Receiving Dipeptidyl Peptidase 4 Inhibitors
Minyoung Lee, Jiyu Sun, Minkyung Han, Yongin Cho, Ji-Yeon Lee, Chung Mo Nam, Eun Seok Kang
Diabetes Care.2019; 42(11): 2057. CrossRef
Dose–response relationship between cigarette smoking and risk of ulcerative colitis: a nationwide population-based study
Seona Park, Jaeyoung Chun, Kyung-Do Han, Hosim Soh, Eun Ae Kang, Hyun Jung Lee, Jong Pil Im, Joo Sung Kim
Journal of Gastroenterology.2019; 54(10): 881. CrossRef
Is androgen deprivation therapy associated with cerebral infarction in patients with prostate cancer? A Korean nationwide population‐based propensity score matching study
Bum Sik Tae, Byeong Jo Jeon, Hoon Choi, Jae Hyun Bae, Jae Young Park
Cancer Medicine.2019; 8(9): 4475. CrossRef
Adult lung transplantation case-volume and in-hospital and long-term mortality in Korea
Susie Yoon, Eun Jin Jang, Ga Hee Kim, Dal Ho Kim, Tae-Yoon Lim, Hannah Lee, Ho Geol Ryu
Journal of Cardiothoracic Surgery.2019;[Epub] CrossRef
Systemic lupus erythematosus is a risk factor for cancer: a nationwide population-based study in Korea
E.H. Bae, S.Y. Lim, K.-D. Han, J.-Hy. Jung, H.S. Choi, C.S. Kim, S.K. Ma, SW Kim
Lupus.2019; 28(3): 317. CrossRef
Association Between Drug Exposure and Occurrence of Parkinsonism in Korea: A Population-Based Case-Control Study
Siin Kim, Sang-Myung Cheon, Hae Sun Suh
Annals of Pharmacotherapy.2019; 53(11): 1102. CrossRef
Validation of diagnostic codes of major clinical outcomes in a National Health Insurance database
Jiesuck Park, Soonil Kwon, Eue-Keun Choi, You-jung Choi, Euijae Lee, Wonseok Choe, So-Ryoung Lee, Myung-Jin Cha, Woo-Hyun Lim, Seil Oh
International Journal of Arrhythmia.2019;[Epub] CrossRef
HDL-Cholesterol, Its Variability, and the Risk of Diabetes: A Nationwide Population-Based Study
Seung-Hwan Lee, Hun-Sung Kim, Yong-Moon Park, Hyuk-Sang Kwon, Kun-Ho Yoon, Kyungdo Han, Mee Kyoung Kim
The Journal of Clinical Endocrinology & Metabolism.2019; 104(11): 5633. CrossRef
Prognostic influence of Korean public medical insurance system on breast cancer patients
Ki-Tae Hwang, Young Wook Ju, Young A Kim, Jongjin Kim, Sohee Oh, Jiwoong Jung, Young Jun Chai, In Sil Choi, So Won Oh
Annals of Surgical Treatment and Research.2019; 96(2): 58. CrossRef
Effect of Case Volume on Mortality After Pediatric Liver Transplantation in Korea
Hannah Lee, Eun Jin Jang, Ga Hee Kim, Nam Joon Yi, Dal Ho Kim, Seokha Yoo, Hyung Sang Row, Chul-Woo Jung, Seung-Young Oh, Ho Geol Ryu
Transplantation.2019; 103(8): 1649. CrossRef
Prescription Patterns and Burden of Pediatric Asthma in Korea
In Suk Sol, Yoon Hee Kim, Soo Yeon Kim, Sun Ha Choi, Jong Deok Kim, Bo Ok Kim, Ji Eun Moon, Kyung Won Kim, Myung Hyun Sohn
Allergy, Asthma & Immunology Research.2019; 11(2): 280. CrossRef
Increased risk of coronary heart disease and stroke in lung cancer survivors: A Korean nationwide study of 20,458 patients
Dong Woog Yoon, Dong Wook Shin, Jong Ho Cho, Jeong Hoon Yang, Su-Min Jeong, Kyungdo Han, Sang Hyun Park
Lung Cancer.2019; 136: 115. CrossRef
Waist Circumference and All-Cause Mortality Independent of Body Mass Index in Korean Population from the National Health Insurance Health Checkup 2009–2015
Yang-Hyun Kim, Seon Mee Kim, Kyung-Do Han, Jin-Hyung Jung, Seong-Su Lee, Sang Woo Oh, Hye Soon Park, Eun-Jung Rhee, Won-Young Lee, Soon Jib Yoo
Journal of Clinical Medicine.2019; 8(1): 72. CrossRef
Temporal trends in prevalence and antithrombotic treatment among Asians with atrial fibrillation undergoing percutaneous coronary intervention: A nationwide Korean population-based study
Jiesuck Park, Eue-Keun Choi, Kyung-Do Han, You-jung Choi, Euijae Lee, Wonseok Choe, So-Ryoung Lee, Myung-Jin Cha, Woo-Hyun Lim, Jeehoon Kang, Kyung Woo Park, Seil Oh, Gregory Y. H. Lip, Chiara Lazzeri
PLOS ONE.2019; 14(1): e0209593. CrossRef
Factors influencing the incidence and treatment of intracranial aneurysm and subarachnoid hemorrhage: time trends and socioeconomic disparities under an universal healthcare system
Won Kyung Lee, Chang Wan Oh, Heeyoung Lee, Kun Sei Lee, Hyeonseon Park
Journal of NeuroInterventional Surgery.2019; 11(2): 159. CrossRef
Increasing trends in hospital care burden of atrial fibrillation in Korea, 2006 through 2015
Daehoon Kim, Pil-Sung Yang, Eunsun Jang, Hee Tae Yu, Tae-Hoon Kim, Jae-Sun Uhm, Jong Youn Kim, Hui-Nam Pak, Moon-Hyoung Lee, Boyoung Joung, Gregory Y H Lip
Heart.2018; 104(24): 2010. CrossRef
Appropriate Amount of Regular Exercise Is Associated with a Reduced Mortality Risk
DA YOUNG LEE, EUN-JUNG RHEE, JUNG HWAN CHO, HYEMI KWON, SE EUN PARK, YANG-HYUN KIM, KYUNGDO HAN, YONG-KYU PARK, SOON JIB YOO, WON-YOUNG LEE
Medicine & Science in Sports & Exercise.2018; 50(12): 2451. CrossRef
The effect of continuity of care on the incidence of end-stage renal disease in patients with newly detected type 2 diabetic nephropathy: a retrospective cohort study
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BMC Nephrology.2018;[Epub] CrossRef
Increased end-stage renal disease risk in patients with inflammatory bowel disease: A nationwide population-based study
Seona Park, Jaeyoung Chun, Kyung-Do Han, Hosim Soh, Kookhwan Choi, Ji Hye Kim, Jooyoung Lee, Changhyun Lee, Jong Pil Im, Joo Sung Kim
World Journal of Gastroenterology.2018; 24(42): 4798. CrossRef
Cardiovascular disease risk differences between bus company employees and general workers according to the Korean National Health Insurance Data
Ji-Hoo Yook, Dong-Wook Lee, Min-Seok Kim, Yun-Chul Hong
Annals of Occupational and Environmental Medicine.2018;[Epub] CrossRef
Impact of Renal Function on Outcomes With Edoxaban in Real-World Patients With Atrial Fibrillation
Hee Tae Yu, Pil-Sung Yang, Tae-Hoon Kim, Eunsun Jang, Daehoon Kim, Jae-Sun Uhm, Jong-Youn Kim, Hui-Nam Pak, Moon-Hyoung Lee, Gregory Y.H. Lip, Boyoung Joung
Stroke.2018; 49(10): 2421. CrossRef
Association between adult height, myocardial infarction, heart failure, stroke and death: a Korean nationwide population-based study
Chan Soon Park, Eue-Keun Choi, Kyung-Do Han, Hyun Jung Lee, Tae-Min Rhee, So-Ryoung Lee, Myung-Jin Cha, Woo-Hyun Lim, Si-Hyuck Kang, Seil Oh
International Journal of Epidemiology.2018; 47(1): 289. CrossRef
Dietary Fat Intake and Risk of Colorectal Cancer: A Systematic Review and Meta-Analysis of Prospective Studies
Minkyeong Kim, Kyong Park
Nutrients.2018; 10(12): 1963. CrossRef
Association Between Changes in Hemoglobin Concentration and Cardiovascular Risks and All‐Cause Mortality Among Young Women
Gyeongsil Lee, Seulggie Choi, Kyuwoong Kim, Jae‐Moon Yun, Joung Sik Son, Su‐Min Jeong, Sung Min Kim, Yeon‐Yong Kim, Seong Yong Park, Youngil Koh, Seung‐sik Hwang, Sang Min Park
Journal of the American Heart Association.2018;[Epub] CrossRef
The economic burden of rotavirus infection in South Korea from 2009 to 2012
Kyung Suk Lee, Ye-Rin Lee, So-Youn Park, In-Hwan Oh, Donald R. Olson
PLOS ONE.2018; 13(3): e0194120. CrossRef
Incidence and death rate of pemphigus vulgaris and pemphigus foliaceus in Korea: A nationwide, population‐based study (2006–2015)
Young Bok Lee, Ji Hyun Lee, Soo Young Lee, Jin‐Wou Kim, Dong Soo Yu, Kyung Do Han, Yong Gyu Park
The Journal of Dermatology.2018; 45(12): 1396. CrossRef
Protective Effect of Metformin Against Thyroid Cancer Development: A Population-Based Study in Korea
Yoon Young Cho, Min Jin Kang, Soo Kyoung Kim, Jung Hwa Jung, Jong Ryeal Hahm, Tae Hyuk Kim, Joo Young Nam, Byung-Wan Lee, Yong-ho Lee, Jae Hoon Chung, Sun Ok Song, Sun Wook Kim
Thyroid.2018; 28(7): 864. CrossRef
Association of oral ciprofloxacin, levofloxacin, ofloxacin and moxifloxacin with the risk of serious ventricular arrhythmia: a nationwide cohort study in Korea
Yongil Cho, Hyun Soo Park
BMJ Open.2018; 8(9): e020974. CrossRef
The risk of alopecia areata and other related autoimmune diseases in patients with sleep disorders: a Korean population–based retrospective cohort study
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Sleep.2018;[Epub] CrossRef
Evaluation of relationships between onychomycosis and vascular diseases using sequential pattern mining
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Scientific Reports.2018;[Epub] CrossRef
Age Threshold for Ischemic Stroke Risk in Atrial Fibrillation
Tae-Hoon Kim, Pil-Sung Yang, Hee Tae Yu, Eunsun Jang, Jae-Sun Uhm, Jong-Youn Kim, Hui-Nam Pak, Moon-Hyoung Lee, Boyoung Joung, Gregory Y.H. Lip
Stroke.2018; 49(8): 1872. CrossRef
Variations of Prevalence and Incidence of Atrial Fibrillation and Oral Anticoagulation Rate According to Different Analysis Approaches
Pil-Sung Yang, Soorack Ryu, Daehoon Kim, Eunsun Jang, Hee Tae Yu, Tae-Hoon Kim, Jinseub Hwang, Boyoung Joung, Gregory Y. H. Lip
Scientific Reports.2018;[Epub] CrossRef
Reciprocal relationship between herpes zoster and cardiovascular diseases: A nationwide population‐based case–control study in Korea
Hyun‐Min Seo, Myung‐Jin Cha, Ju Hee Han, Kyungdo Han, Sang Hyun Park, Chul Hwan Bang, Ji Hyun Lee, Jun Young Lee, Eue‐Keun Choi, Young Min Park
The Journal of Dermatology.2018; 45(11): 1312. CrossRef
Hypertension and risk of psoriasis incidence: An 11-year nationwide population-based cohort study
Ha-Na Kim, Kyungdo Han, Sang-Wook Song, Ji Hyun Lee, Valerio De Vita
PLOS ONE.2018; 13(8): e0202854. CrossRef
Association between abdominal obesity and increased risk for the development of hypertension regardless of physical activity: A nationwide population‐based study
Eun‐Jung Rhee, Jung‐Hwan Cho, Hyemi Kwon, Se‐Eun Park, Jin‐Hyung Jung, Kyung‐Do Han, Yong‐Gyu Park, Hye Soon Park, Yang‐Hyun Kim, Soon‐Jib Yoo, Won‐Young Lee
The Journal of Clinical Hypertension.2018; 20(10): 1417. CrossRef
Prevalence of extraintestinal manifestations in Korean inflammatory bowel disease patients
Bo Ram Yang, Nam-Kyong Choi, Mi-Sook Kim, Jaeyoung Chun, Sang Hyun Joo, Hyesung Kim, Joongyub Lee, Gang Liu
PLOS ONE.2018; 13(7): e0200363. CrossRef
Need for Systematic Efforts to Modify Health-Related Behaviors After Acute Myocardial Infarction in Korea
Seungwoo Cha, Jin Joo Park, Sunyoung Kim, Hong-Yup Ahn, Kyungdo Han, Yookyung Lee, Won-Seok Kim, Nam-Jong Paik
Circulation Journal.2018; 82(10): 2523. CrossRef
Association between diabetes and asthma
Ji Yeon Baek, Seung Eun Lee, Kyungdo Han, Eun Hee Koh
Annals of Allergy, Asthma & Immunology.2018; 121(6): 699. CrossRef
Association between Height and Actinic Keratosis: A Nationwide Population-based Study in South Korea
Young Bok Lee, Ji Hyun Lee, Min Ji Kang, Jin-Wou Kim, Dong Soo Yu, Kyung Do Han, Yong Gyu Park
Scientific Reports.2018;[Epub] CrossRef
Effect of Institutional Case Volume on In-Hospital Mortality After Deceased Donor Liver Transplantation: A Nationwide Retrospective Cohort Study in Korea
S. Yoo, E.J. Jang, G.H. Kim, D.H. Kim, S.M. Kwon, H. Lee, C.-W. Jung, H.G. Ryu
Transplantation Proceedings.2018; 50(10): 3644. CrossRef
Past and Current Status of Adult Type 2 Diabetes Mellitus Management in Korea: A National Health Insurance Service Database Analysis
Seung-Hyun Ko, Kyungdo Han, Yong-ho Lee, Junghyun Noh, Cheol-Young Park, Dae-Jung Kim, Chang Hee Jung, Ki-Up Lee, Kyung-Soo Ko
Diabetes & Metabolism Journal.2018; 42(2): 93. CrossRef
Difference in prostate cancer incidence around sixty years: effects of age and metabolic diseases
Jin Bong Choi, Jung Ho Kim, Sung‐Hoo Hong, Kyung‐Do Han, U‐Syn Ha
Cancer Medicine.2018; 7(6): 2736. CrossRef
A nationwide population-based study of common bile duct stone recurrence after endoscopic stone removal in Korea
Byung Kyu Park, Jeong Hun Seo, Han Ho Jeon, Jong Won Choi, Sun Young Won, Yong Suk Cho, Chun Kyon Lee, Haeyong Park, Dong Wook Kim
Journal of Gastroenterology.2018; 53(5): 670. CrossRef
Estimating the impact of body mass index on bladder cancer risk: Stratification by smoking status
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Scientific Reports.2018;[Epub] CrossRef
Prevalence of Obesity and Incidence of Obesity-Related Comorbidities in Koreans Based on National Health Insurance Service Health Checkup Data 2006–2015
Mi Hae Seo, Yang-Hyun Kim, Kyungdo Han, Jin-Hyung Jung, Yong-Gyu Park, Seong-Su Lee, Hyuk-Sang Kwon, Won-Young Lee, Soon Jib Yoo
Journal of Obesity & Metabolic Syndrome.2018; 27(1): 46. CrossRef
Association of Hemoglobin Concentration and Its Change With Cardiovascular and All‐Cause Mortality
Gyeongsil Lee, Seulggie Choi, Kyuwoong Kim, Jae‐Moon Yun, Joung Sik Son, Su‐Min Jeong, Sung Min Kim, Sang Min Park
Journal of the American Heart Association.2018;[Epub] CrossRef
Impact of acupuncture treatment on the lumbar surgery rate for low back pain in Korea: A nationwide matched retrospective cohort study
Wonil Koh, Kyungwon Kang, Yoon Jae Lee, Me-riong Kim, Joon-Shik Shin, Jinho Lee, Jun-Hwan Lee, Kyung-Min Shin, In-Hyuk Ha, Qinhong Zhang
PLOS ONE.2018; 13(6): e0199042. CrossRef
The influence of diabetes and antidiabetic medications on the risk of pancreatic cancer: a nationwide population-based study in Korea
Da Young Lee, Ji Hee Yu, Sanghyun Park, Kyungdo Han, Nam Hoon Kim, Hye Jin Yoo, Kyung Mook Choi, Sei Hyun Baik, Nan Hee Kim, Ji A. Seo
Scientific Reports.2018;[Epub] CrossRef
Validation of Administrative Big Database for Colorectal Cancer Searched by International Classification of Disease 10th Codes in Korean: A Retrospective Big-cohort Study
Young-Jae Hwang, Nayoung Kim, Chang Yong Yun, Hyuk Yoon, Cheol Min Shin, Young Soo Park, Il Tae Son, Heung-Kwon Oh, Duck-Woo Kim, Sung-Bum Kang, Hye Seung Lee, Seon Mee Park, Dong Ho Lee
Journal of Cancer Prevention.2018; 23(4): 183. CrossRef
J-Shaped Association Between Postoperative Levothyroxine Dosage and Fracture Risk in Thyroid Cancer Patients: A Retrospective Cohort Study
Dong Wook Shin, Beomseok Suh, Hyunsun Lim, Jae Moon Yun, Sun Ok Song, Youngmin Park
Journal of Bone and Mineral Research.2018; 33(6): 1037. CrossRef
Liver cirrhosis and cancer: comparison of mortality
Wankyo Chung, Changik Jo, Woo Jin Chung, Dong Joon Kim
Hepatology International.2018; 12(3): 269. CrossRef
Risk of ischemic stroke in metabolically healthy obesity: A nationwide population-based study
Hyun-Jung Lee, Eue-Keun Choi, Seung-Hwan Lee, Yong-Jin Kim, Kyung-Do Han, Seil Oh, Manlio Vinciguerra
PLOS ONE.2018; 13(3): e0195210. CrossRef
Incidence, prevalence, and mortality of Adamantiades‐Behçet's disease in Korea: a nationwide, population‐based study (2006–2015)
Y.B. Lee, S.Y. Lee, J.Y. Choi, J.H. Lee, H.S. Chae, J.W. Kim, K.D. Han, Y.G. Park, D.S. Yu
Journal of the European Academy of Dermatology and Venereology.2018; 32(6): 999. CrossRef
Temporal trends of antithrombotic therapy for stroke prevention in Korean patients with non-valvular atrial fibrillation in the era of non-vitamin K antagonist oral anticoagulants: A nationwide population-based study
So-Ryoung Lee, Eue-Keun Choi, Kyung-Do Han, Myung-Jin Cha, Seil Oh, Gregory Y. H. Lip, Thanh G Phan
PLOS ONE.2017; 12(12): e0189495. CrossRef
Persistent smoking after a cardiovascular event: A nationwide retrospective study in Korea
Yoo Kyoung Lim, Dong Wook Shin, Hyeon Suk Kim, Jae Moon Yun, Jung-Hyun Shin, Hyejin Lee, Hye Yeon Koo, Min Jung Kim, Jeong Yeon Yoon, Mi Hee Cho, Katriina Aalto-Setala
PLOS ONE.2017; 12(10): e0186872. CrossRef
Change in Weight and Body Mass Index Associated With All-Cause Mortality in Korea: A Nationwide Longitudinal Study
Yang-Hyun Kim, Seon Mee Kim, Kyung-do Han, Jang-Won Son, Seong-Su Lee, Sang Woo Oh, Won-Young Lee, Soon Jib Yoo
The Journal of Clinical Endocrinology & Metabolism.2017; 102(11): 4041. CrossRef
Secondary Primary Prostate Cancer after Colorectal Cancer: A Nationwide Population-based Cohort Study in Korea
Hyun Soo Kim, Yoon Jin Choi, Dong Woo Shin, Kyung-Do Han, Hyuk Yoon, Cheol Min Shin, Young Soo Park, Nayoung Kim, Dong Ho Lee
Journal of Cancer Prevention.2017; 22(4): 241. CrossRef
Increasing burden of liver cancer despite extensive use of antiviral agents in a hepatitis B virus‐endemic population
Jonggi Choi, Seungbong Han, Namkug Kim, Young‐Suk Lim
Hepatology.2017; 66(5): 1454. CrossRef
Data Analytic Process of a Nationwide Population-Based Study on Obesity Using the National Health Information Database Presented by the National Health Insurance Service 2006-2015
Yang-Hyun Kim, Kyungdo Han, Jang-Won Son, Seong-Su Lee, Sang Woo Oh, Hyuk-Sang Kwon, Soon-Ae Shin, Yeon-Yong Kim, Won-Young Lee, Soon Jib Yoo
Journal of Obesity & Metabolic Syndrome.2017; 26(1): 23. CrossRef
Trends in the incidence and prevalence of atrial fibrillation and estimated thromboembolic risk using the CHA2DS2-VASc score in the entire Korean population
So-Ryoung Lee, Eue-Keun Choi, Kyung-Do Han, Myung-Jin Cha, Seil Oh
International Journal of Cardiology.2017; 236: 226. CrossRef
Home Return After Surgery in Patients Aged over 85 Years is Associated with Preoperative Albumin Levels, the Type of Surgery, and APACHE II Score
Bora Lee, Sungwon Na, Miran Park, Sungyeon Ham, Jeongmin Kim
World Journal of Surgery.2017; 41(4): 919. CrossRef
Atrial fibrillation and the risk of myocardial infarction: a nation-wide propensity-matched study
Hye Young Lee, Pil-Sung Yang, Tae-Hoon Kim, Jae-Sun Uhm, Hui-Nam Pak, Moon-Hyoung Lee, Boyoung Joung
Scientific Reports.2017;[Epub] CrossRef
Regional variations in frequency of glycosylated hemoglobin (HbA1c) monitoring in Korea: A multilevel analysis of nationwide data
Kyoung-Hun Yoo, Dong-Wook Shin, Mi-Hee Cho, Sang-Hyuck Kim, Hyun-Jung Bahk, Shin-Hye Kim, Su-Min Jeong, Jae-Moon Yun, Jin-Ho Park, Heesun Kim, BeLong Cho
Diabetes Research and Clinical Practice.2017; 131: 61. CrossRef
Pediatric fluoroquinolone prescription in South Korea before and after a regulatory intervention: A nationwide study, 2007-2015
Seung Yeon Song, Joo Hee Shin, Su Yeong Hyeon, Donguk Kim, Won Ku Kang, Soo-Han Choi, Yae-Jean Kim, Eun Young Kim, Ravi Jhaveri
PLOS ONE.2017; 12(5): e0176420. CrossRef
Recent Shift of Body Mass Index Distribution in Korea: a Population-based Korea National Health Insurance Database, 2002–2013
Yeong Sook Yoon, Sang Woo Oh
Journal of Korean Medical Science.2017; 32(3): 434. CrossRef
Increased risk of thyroid diseases in patients with systemic lupus erythematosus: A nationwide population-based Study in Korea
Jae-Seung Yun, Jung Min Bae, Ki-Jo Kim, Yu Seok Jung, Gyong Moon Kim, Hyung-Rae Kim, Jun-Seok Lee, Seung-Hyun Ko, Seon-Ah Cha, Yu-Bae Ahn, Ludmila Prokunina-Olsson
PLOS ONE.2017; 12(6): e0179088. CrossRef
Trends in the pervasiveness of type 2 diabetes, impaired fasting glucose and co-morbidities during an 8-year-follow-up of nationwide Korean population
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Scientific Reports.2017;[Epub] CrossRef
Impact of National Health Checkup Service on Hard Atherosclerotic Cardiovascular Disease Events and All-Cause Mortality in the General Population
Yongsung Suh, Chan Joo Lee, Deok-Kyu Cho, Yun-Hyeong Cho, Dong-Ho Shin, Chul-Min Ahn, Jung-Sun Kim, Byeong-Keuk Kim, Young-Guk Ko, Donghoon Choi, Yangsoo Jang, Myeong-Ki Hong
The American Journal of Cardiology.2017; 120(10): 1804. CrossRef
Data Analytic Process of a Nationwide Population-Based Study Using National Health Information Database Established by National Health Insurance Service
Yong-ho Lee, Kyungdo Han, Seung-Hyun Ko, Kyung Soo Ko, Ki-Up Lee
Diabetes & Metabolism Journal.2016; 40(1): 79. CrossRef
Trends in Diabetes Incidence in the Last Decade Based on Korean National Health Insurance Claims Data
Sun Ok Song, Yong-ho Lee, Dong Wook Kim, Young Duk Song, Joo Young Nam, Kyoung Hye Park, Dae Jung Kim, Seok Won Park, Hyun Chul Lee, Byung-Wan Lee
Endocrinology and Metabolism.2016; 31(2): 292. CrossRef
Obesity, metabolic health, and mortality in adults: a nationwide population-based study in Korea
Hae Kyung Yang, Kyungdo Han, Hyuk-Sang Kwon, Yong-Moon Park, Jae-Hyoung Cho, Kun-Ho Yoon, Moo-Il Kang, Bong-Yun Cha, Seung-Hwan Lee
Scientific Reports.2016;[Epub] CrossRef
Epidemiology of Type 1 Diabetes Mellitus in Korea through an Investigation of the National Registration Project of Type 1 Diabetes for the Reimbursement of Glucometer Strips with Additional Analyses Using Claims Data
Sun Ok Song, Young Duk Song, Joo Young Nam, Kyeong Hye Park, Ji-Hae Yoon, Kyung-Mi Son, Young Ko, Dong-Ha Lim
Diabetes & Metabolism Journal.2016; 40(1): 35. CrossRef
Central nervous system diseases of organic solvents exposed workers based on nationwide medical surveillance‐data in Korea
Young‐Sun Min, Yeon‐Soon Ahn
American Journal of Industrial Medicine.2016; 59(5): 392. CrossRef
Metabolic Risk Profile and Cancer in Korean Men and Women
Seulki Ko, Seok-Jun Yoon, Dongwoo Kim, A-Rim Kim, Eun-Jung Kim, Hye-Young Seo
Journal of Preventive Medicine and Public Health.2016; 49(3): 143. CrossRef
Trends of antidiabetic drug use in adult type 2 diabetes in Korea in 2002–2013
Seung-Hyun Ko, Dae-Jung Kim, Jong-Heon Park, Cheol-Young Park, Chang Hee Jung, Hyuk-Sang Kwon, Joong-Yeol Park, Kee-Ho Song, Kyungdo Han, Ki-Up Lee, Kyung-Soo Ko
Medicine.2016; 95(27): e4018. CrossRef
Hypoglycemia is associated with dementia in elderly patients with type 2 diabetes mellitus: An analysis based on the Korea National Diabetes Program Cohort
Sang Ouk Chin, Sang Youl Rhee, Suk Chon, Sei Hyun Baik, Yongsoo Park, Moon Suk Nam, Kwan Woo Lee, Ki Hong Chun, Jeong-taek Woo, Young Seol Kim
Diabetes Research and Clinical Practice.2016; 122: 54. CrossRef
How Can We Identify the Elimination of Infectious Diseases? Experience From an Active Measles Laboratory Surveillance System in the Republic of Korea
Tae Un Yang, Hae Ji Kang, Hye Eun Eom, Young-Joon Park, Ok Park, Su Jin Kim, Jeong-Gu Nam, Sung Soon Kim, Eun Kyeong Jeong
Asia Pacific Journal of Public Health.2015; 27(8_suppl): 101S. CrossRef
The Population-Based Risk of Need for Coronary Revascularization According to the Presence of Type 2 Diabetes Mellitus and History of Coronary Heart Disease in the Korean Population
Chang Hee Jung, Gi Hyeon Seo, Sunghwan Suh, Ji Cheol Bae, Mee Kyoung Kim, You-Cheol Hwang, Jae Hyeon Kim, Byung-Wan Lee, Xian Wu Cheng
PLOS ONE.2015; 10(6): e0128627. CrossRef
Response: Increased Risk of Hospitalization for Heart Failure with Newly Prescribed Dipeptidyl Peptidase-4 Inhibitors and Pioglitazone Using the Korean Health Insurance Claims Database (Diabetes Metab J2015;39:247-52)
Sunghwan Suh, Gi Hyeon Seo, Chang Hee Jung, Mee-Kyoung Kim, Sang-Man Jin, You-Cheol Hwang, Byung-Wan Lee, Jae Hyeon Kim
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Overspecialized and undertrained? Patient diversity encountered by medical students during their internal medicine clerkship at a university hospital
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The Effect of DPP-4 Inhibitors on Metabolic Parameters in Patients with Type 2 Diabetes: Eun Yeong Choe, Yongin Cho, Younjeong Choi, Yujung Yun, Hye Jin Wang, Obin Kwon, Byung-Wan Lee, Chul Woo Ahn, Bong Soo Cha, Hyun Chul Lee, Eun Seok Kang; Diabetes Metab J. 2014;38(3):211-219. Published online June 17, 2014; DOI: https://doi.org/10.4093/dmj.2014.38.3.211

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Background

We evaluated the effects of two dipeptidyl peptidase-4 (DPP-4) inhibitors, sitagliptin and vildagliptin, on metabolic parameters in patients with type 2 diabetes mellitus.

Methods

A total of 170 type 2 diabetes patients treated with sitagliptin or vildagliptin for more than 24 weeks were selected. The patients were separated into two groups, sitagliptin (100 mg once daily, n=93) and vildagliptin (50 mg twice daily, n=77). We compared the effect of each DPP-4 inhibitor on metabolic parameters, including the fasting plasma glucose (FPG), postprandial glucose (PPG), glycated hemoglobin (HbA1c), and glycated albumin (GA) levels, and lipid parameters at baseline and after 24 weeks of treatment.

Results

The HbA1c, FPG, and GA levels were similar between the two groups at baseline, but the sitagliptin group displayed a higher PPG level (P=0.03). After 24 weeks of treatment, all of the glucose-related parameters were significantly decreased in both groups (P=0.001). The levels of total cholesterol and triglycerides were only reduced in the vildagliptin group (P=0.001), although the sitagliptin group received a larger quantity of statins than the vildagliptin group (P=0.002).The mean change in the glucose- and lipid-related parameters after 24 weeks of treatment were not significantly different between the two groups (P=not significant). Neither sitagliptin nor vildagliptin treatment was associated with a reduction in the high sensitive C-reactive protein level (P=0.714).

Conclusion

Vildagliptin and sitagliptin exert a similar effect on metabolic parameters, but vildagliptin exerts a more potent beneficial effect on lipid parameters.

Citations

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Indian Journal of Endocrinology and Metabolism.2019; 23(3): 312. CrossRef
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Risk of Myopathy Associated With DPP-4 Inhibitors in Combination With Statins: A Disproportionality Analysis Using Data From the WHO and French Spontaneous Reporting Databases
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Soluble DPP-4 up-regulates toll-like receptors and augments inflammatory reactions, which are ameliorated by vildagliptin or mannose-6-phosphate
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Response: The Effect of DPP-4 Inhibitors on Metabolic Parameters in Patients with Type 2 Diabetes (Diabetes Metab J2014;38:211-9)
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Glycemic Effectiveness of Metformin-Based Dual-Combination Therapies with Sulphonylurea, Pioglitazone, or DPP4-Inhibitor in Drug-Naïve Korean Type 2 Diabetic Patients: Young Ki Lee, Sun Ok Song, Kwang Joon Kim, Yongin Cho, Younjeong Choi, Yujung Yun, Byung-Wan Lee, Eun-Seok Kang, Bong Soo Cha, Hyun Chul Lee; Diabetes Metab J. 2013;37(6):465-474. Published online December 12, 2013; DOI: https://doi.org/10.4093/dmj.2013.37.6.465

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Abstract PDF PubReader

Background

This study compared the glycemic effectiveness of three metformin-based dual therapies according to baseline hemoglobin A1c (HbA1c) to evaluate the appropriateness of the guideline enforced by the National Health Insurance Corporation of Korea for initial medication of type 2 diabetes (T2D).

Methods

This prospective observational study was conducted across 24 weeks for drug-naïve Korean T2D patients with HbA1c greater than 7.5%. Subjects were first divided into three groups based on the agent combined with metformin (group 1, gliclazide-modified release or glimepiride; group 2, pioglitazone; group 3, sitagliptin). Subjects were also classified into three categories according to baseline HbA1c (category I, 7.5%≤HbA1c<9.0%; category II, 9.0%≤HbA1c<11.0%; category III, 11.0%≤HbA1c).

Results

Among 116 subjects, 99 subjects completed the study, with 88 subjects maintaining the initial medication. While each of the metformin-based dual therapies showed a significant decrease in HbA1c (group 1, 8.9% to 6.4%; group 2, 9.0% to 6.6%; group 3, 9.3% to 6.3%; P<0.001 for each), there was no significant difference in the magnitude of HbA1c change among the groups. While the three HbA1c categories showed significantly different baseline HbA1c levels (8.2% vs. 9.9% vs. 11.9%; P<0.001), endpoint HbA1c was not different (6.4% vs. 6.6% vs. 6.0%; P=0.051).

Conclusion

The three dual therapies using a combination of metformin and either sulfonylurea, pioglitazone, or sitagliptin showed similar glycemic effectiveness among drug-naïve Korean T2D patients. In addition, these regimens were similarly effective across a wide range of baseline HbA1c levels.

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Review

Refocusing Peroxisome Proliferator Activated Receptor-α: A New Insight for Therapeutic Roles in Diabetes: Hannah Seok, Bong Soo Cha; Diabetes Metab J. 2013;37(5):326-332. Published online October 17, 2013; DOI: https://doi.org/10.4093/dmj.2013.37.5.326

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Abstract PDF PubReader

Although glucose-lowering treatment shows some risk lowering effects in cardiovascular diseases, risks of macrovascular and microvascular complications have still remained, and development of new therapeutic strategies is needed. Recent data have shown that peroxisome proliferator activated receptor-α (PPAR-α) plays a pivotal role in the regulation of lipid homeostasis, fatty acid oxidation, cellular differentiation, and immune response such as inflammation or vascularization related to diabetic complication. This review will re-examine the metabolic role of PPAR-α, summarize data from clinical studies on the effect of PPAR-α agonist in diabetes, and will discuss the possible therapeutic role of PPAR-α activation.

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Original Article

Safety and Efficacy of Modern Insulin Analogues: Hye Jin Yoo, Keun Yong Park, Kang Seo Park, Kyu Jeung Ahn, Kyung Wan Min, Jeong Hyun Park, Sang Ah Chang, Bong Soo Cha, Dong-Jun Kim, Yong Seong Kim, Tae Keun Oh, Suk Chon, Il Seong Nam-Goong, Mi Jin Kim, Hye-Soon Kim, Young Sik Choi, You Hern Ahn, Sora Lee, Sei Hyun Baik; Diabetes Metab J. 2013;37(3):181-189. Published online June 14, 2013; DOI: https://doi.org/10.4093/dmj.2013.37.3.181

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Abstract PDF PubReader

Background

A1chieve® was a noninterventional study evaluating the clinical safety and efficacy of biphasic insulin aspart 30, insulin detemir, and insulin aspart.

Methods

Korean type 2 diabetes patients who have not been treated with the study insulin or have started it within 4 weeks before enrollment were eligible for the study. The patient selection and the choice of regimen were at the discretion of the physician. The safety and efficacy information was collected from the subjects at baseline, week 12, and week 24. The number of serious adverse drug reactions (SADRs) was the primary endpoint. The changes of clinical diabetic markers at week 12 and/or at week 24 compared to baseline were the secondary endpoints.

Results

Out of 4,058 exposed patients, 3,003 completed the study. During the study period, three SADRs were reported in three patients (0.1%). No major hypoglycemic episodes were observed and the rate of minor hypoglycemic episodes marginally decreased during 24 weeks (from 2.77 to 2.42 events per patient-year). The overall quality of life score improved (from 66.7±15.9 to 72.5±13.5) while the mean body weight was slightly increased (0.6±3.0 kg). The 24-week reductions in glycated hemoglobin, fasting plasma glucose and postprandial plasma glucose were 1.6%±2.2%, 2.5±4.7 mmol/L, and 4.0±6.4 mmol/L, respectively.

Conclusion

The studied regimens showed improvements in glycemic control with low incidence of SADRs, including no incidence of major hypoglycemic episodes in Korean patients with type 2 diabetes.

Citations

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Sun Ok Song, You-Cheol Hwang, Kyu-Jeung Ahn, Bong Soo Cha, Young Duk Song, Dae Wook Lee, Byung-Wan Lee
Diabetes Therapy.2015; 6(4): 547. CrossRef
The optimal morning:evening ratio in total dose of twice‐daily biphasic insulin analogue in poorly controlled Type 2 diabetes: a 24‐week multi‐centre prospective, randomized controlled, open‐labelled clinical study
C. H. Jung, J.‐Y. Park, J. H. Cho, K.‐H. Yoon, H. K. Yang, Y.‐H. Lee, B. S. Cha, B.‐W. Lee
Diabetic Medicine.2014; 31(1): 68. CrossRef
The glycemic efficacies of insulin analogue regimens according to baseline glycemic status in Korean patients with type 2 diabetes: sub‐analysis from the A 1 chieve ® study
Y.‐C. Hwang, J. G. Kang, K. J. Ahn, B. S. Cha, S.‐H. Ihm, S. Lee, M. Kim, B.‐W. Lee
International Journal of Clinical Practice.2014; 68(11): 1338. CrossRef
Letter: Efficacy and Safety of Biphasic Insulin Aspart 30/70 in Type 2 Diabetes Suboptimally Controlled on Oral Antidiabetic Therapy in Korea: A Multicenter, Open-Label, Single-Arm Study (Diabetes Metab J2013;37:117-24)
Byung-Wan Lee
Diabetes & Metabolism Journal.2013; 37(3): 212. CrossRef

Response

Response: Balsamic Vinegar Improves High Fat-Induced Beta Cell Dysfunction via Beta Cell ABCA1 (Diabetes Metab J 2012;36:275-9): Hannah Seok, Bong Soo Cha; Diabetes Metab J. 2012;36(5):390-390. Published online October 18, 2012; DOI: https://doi.org/10.4093/dmj.2012.36.5.390

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Citations

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Effect and mechanisms of action of vinegar on glucose metabolism, lipid profile, and body weight
Eleni I Petsiou, Panayota I Mitrou, Sotirios A Raptis, George D Dimitriadis
Nutrition Reviews.2014; 72(10): 651. CrossRef

Original Articles

The Risk of Bladder Cancer in Korean Diabetic Subjects Treated with Pioglitazone: Sun Ok Song, Kwang Joon Kim, Byung-Wan Lee, Eun Seok Kang, Bong Soo Cha, Hyun Chul Lee; Diabetes Metab J. 2012;36(5):371-378. Published online October 18, 2012; DOI: https://doi.org/10.4093/dmj.2012.36.5.371

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Background

There is growing concern regarding the increased incidence of bladder cancer in diabetic patients using pioglitazone. This study aimed to investigate the association between bladder cancer and the use of pioglitazone in Korean diabetics.

Methods

This retrospective, matched case-control study included a case group (n=329) of diabetic patients with bladder cancer who presented at the Severance Hospital from November 2005 to June 2011. The control group consisted of patients without bladder cancer (1:2 ratio matching for sex and age, n=658) who were listed on the Severance Hospital diabetes registry.

Results

The percentage of subjects who had ever used pioglitazone was significantly lower in the case group than in the control group (6.4% vs. 15.0%, P<0.001). Multivariate conditional logistic analysis revealed that independent factors affecting bladder cancer were smoking (odds ratio [OR], 11.64; 95% confidence interval [CI], 6.56 to 20.66; P<0.001), coexisting cancer (OR, 6.11; 95% CI, 2.25 to 16.63; P<0.001), and hemoglobin levels (OR, 0.78; 95% CI, 0.69 to 0.88; P<0.001). The OR of the history of pioglitazone use was 2.09 and was not significantly different between the two groups (95% CI, 0.26 to 16.81; P=0.488).

Conclusion

A relationship between pioglitazone use and incidence of bladder cancer was not observed in Korean diabetic patients. This suggests that the risk for bladder cancer in Korean diabetic subjects treated with pioglitazone might be different from that of Caucasian populations. Large-scale, well-designed and multi-center studies are needed to further evaluate this relationship.

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Balsamic Vinegar Improves High Fat-Induced Beta Cell Dysfunction via Beta Cell ABCA1: Hannah Seok, Ji Young Lee, Eun Mi Park, Se Eun Park, Jae Hyuk Lee, Seungtaek Lim, Byung-Wan Lee, Eun Seok Kang, Hyun Chul Lee, Bong Soo Cha; Diabetes Metab J. 2012;36(4):275-279. Published online August 20, 2012; DOI: https://doi.org/10.4093/dmj.2012.36.4.275

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Background

The aim of this study was to investigate the effects of balsamic vinegar on β-cell dysfunction.

Methods

In this study, 28-week-old Otsuka Long-Evans Tokushima Fatty (OLETF) rats were fed a normal chow diet or a high-fat diet (HFD) and were provided with tap water or dilute balsamic vinegar for 4 weeks. Oral glucose tolerance tests and histopathological analyses were performed thereafter.

Results

In rats fed both the both chow diet and the HFD, the rats given balsamic vinegar showed increased insulin staining in islets compared with tap water administered rats. Balsamic vinegar administration also increased β-cell ATP-binding cassette transporter subfamily A member 1 (ABCA1) expression in islets and decreased cholesterol levels.

Conclusion

These findings provide the first evidence for an anti-diabetic effect of balsamic vinegar through improvement of β-cell function via increasing β-cell ABCA1 expression.

Citations

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The herbal extract ALS-L1023 from Melissa officinalis reduces weight gain, elevated glucose levels and β-cell loss in Otsuka Long-Evans Tokushima fatty rats
Yujin Shin, Dongju Lee, Jiwon Ahn, Mijeong Lee, Soon Shik Shin, Michung Yoon
Journal of Ethnopharmacology.2021; 264: 113360. CrossRef
The Effect of Balsamic Vinegar Dressing on Protein and Carbohydrate Digestibility is Dependent on the Food Matrix
Eleonora Urbinati, Mattia Di Nunzio, Gianfranco Picone, Elena Chiarello, Alessandra Bordoni, Francesco Capozzi
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Safety and side effects of apple vinegar intake and its effect on metabolic parameters and body weight: a systematic review
Tine Louise Launholt, Christina Blanner Kristiansen, Peter Hjorth
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Nypa fruticans Wurmb. Vinegar’s Aqueous Extract Stimulates Insulin Secretion and Exerts Hepatoprotective Effect on STZ-Induced Diabetic Rats
Nor Yusoff, Vuanghao Lim, Bassel Al-Hindi, Khairul Abdul Razak, Tri Widyawati, Dwi Anggraini, Mariam Ahmad, Mohd Asmawi
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Pancreas.2016; 45(3): 317. CrossRef
Chemical Characteristics and Immuno-Stimulatory Activity of Polysaccharides from Fermented Vinegars Manufactured with Different Raw Materials
Dong-Su Kim, Byung Serk Hurh, Kwang-Soon Shin
Journal of the Korean Society of Food Science and Nutrition.2015; 44(2): 191. CrossRef
Effect and mechanisms of action of vinegar on glucose metabolism, lipid profile, and body weight
Eleni I Petsiou, Panayota I Mitrou, Sotirios A Raptis, George D Dimitriadis
Nutrition Reviews.2014; 72(10): 651. CrossRef
Chemical Property and Macrophage Stimulating Activity of Polysaccharides isolated from Brown Rice and Persimmon Vinegars
Dong-Su Kim, Kwang-Soon Shin
The Korean Journal of Food And Nutrition.2014; 27(6): 1033. CrossRef
Vinegar ingestion at mealtime reduced fasting blood glucose concentrations in healthy adults at risk for type 2 diabetes
Carol S. Johnston, Samantha Quagliano, Serena White
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Glycemic Effects of Once-a-Day Rapid-Acting Insulin Analogue Addition on a Basal Insulin Analogue in Korean Subjects with Poorly Controlled Type 2 Diabetes Mellitus: Eun Yeong Choe, Yong-ho Lee, Byung-Wan Lee, Eun-Seok Kang, Bong Soo Cha, Hyun Chul Lee; Diabetes Metab J. 2012;36(3):230-236. Published online June 14, 2012; DOI: https://doi.org/10.4093/dmj.2012.36.3.230

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Background

The present study investigates the efficacy in glycemic control by adding once-a-day glulisine to glargine as a basal plus regimen and factors influencing glycemic control with the basal plus regimen in Korean subjects with type 2 diabetes.

Methods

In the present retrospective study, subjects previously treated with the basal plus regimens for at least 6 months were reviewed. Changes in glycemic profiles and clinical parameters were evaluated.

Results

A total of 87 subjects were ultimately enrolled in this study. At baseline, mean glycated hemoglobin (A1c) and glycated albumin were 8.5% (8.0% to 9.6%) and 25.2±7.6%, respectively. After treatment with the basal plus regimen, patients had significant reductions of A1c at 6 months (0.8±0.1%, P<0.001) and their postprandial glucose levels were decreased by 48.7±10.3 mg/dL (P<0.001). Multiple logistic regression showed old age (odds ratio [OR], 1.25; 95% confidence interval [CI], 1.02 to 1.55), high initial A1c (OR, 22.21; 95% CI, 2.44 to 201.78), and lower amounts of glargine (OR, 0.85; 95% CI, 0.76 to 0.99), and glimepiride (OR, 0.23; 95% CI, 0.06 to 0.93) at baseline were independently associated with good responders whose A1c reduction was more than 0.5%.

Conclusion

The authors suggest a basal plus regimen may be effective in reducing glucose levels of subjects with old age, high initial A1c, and patients on low doses of glimepiride and glargine. Despite the use of high doses of hypoglycemic agents, elderly patients with poorly-controlled diabetes are preferred for early initiation of the basal plus regimen.

Citations

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Addition of a single short-acting insulin bolus to basal insulin-supported oral therapy: a systematic review of data on the basal-plus regimen
Jochen Seufert, Anja Borck, Peter Bramlage
BMJ Open Diabetes Research & Care.2019; 7(1): e000679. CrossRef
Titration of basal insulin or immediate addition of rapid acting insulin in patients not at target using basal insulin supported oral antidiabetic treatment – A prospective observational study in 2202 patients
Thorsten Siegmund, Martin Pfohl, Thomas Forst, Stefan Pscherer, Peter Bramlage, Johannes Foersch, Anja Borck, Jochen Seufert
Diabetes & Metabolic Syndrome: Clinical Research & Reviews.2017; 11(1): 51. CrossRef
Characteristics Predictive for a Successful Switch from Insulin Analogue Therapy to Oral Hypoglycemic Agents in Patients with Type 2 Diabetes
Gyuri Kim, Yong-ho Lee, Eun Seok Kang, Bong-Soo Cha, Hyun Chul Lee, Byung-Wan Lee
Yonsei Medical Journal.2016; 57(6): 1395. CrossRef
Clinical Characteristics of Patients Responding to Once-Daily Basal Insulin Therapy in Korean Subjects with Type 2 Diabetes
Sun Ok Song, You-Cheol Hwang, Kyu-Jeung Ahn, Bong Soo Cha, Young Duk Song, Dae Wook Lee, Byung-Wan Lee
Diabetes Therapy.2015; 6(4): 547. CrossRef
The optimal morning:evening ratio in total dose of twice‐daily biphasic insulin analogue in poorly controlled Type 2 diabetes: a 24‐week multi‐centre prospective, randomized controlled, open‐labelled clinical study
C. H. Jung, J.‐Y. Park, J. H. Cho, K.‐H. Yoon, H. K. Yang, Y.‐H. Lee, B. S. Cha, B.‐W. Lee
Diabetic Medicine.2014; 31(1): 68. CrossRef
The glycemic efficacies of insulin analogue regimens according to baseline glycemic status in Korean patients with type 2 diabetes: sub‐analysis from the A 1 chieve ® study
Y.‐C. Hwang, J. G. Kang, K. J. Ahn, B. S. Cha, S.‐H. Ihm, S. Lee, M. Kim, B.‐W. Lee
International Journal of Clinical Practice.2014; 68(11): 1338. CrossRef

Perception of Clinicians and Diabetic Patients on the Importance of Postprandial Glucose Control and Diabetes Education Status: A Cross Sectional Survey: Ji Hun Choi, Cheol Young Park, Bong Soo Cha, In Joo Kim, Tae Sun Park, Joong Yeol Park, Kyung Soo Park, Kun Ho Yoon, In Kyu Lee, Sung Woo Park; Diabetes Metab J. 2012;36(2):120-127. Published online April 17, 2012; DOI: https://doi.org/10.4093/dmj.2012.36.2.120

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Background

Recent studies have shown the importance of postprandial glucose (PPG) in the development of diabetes complications. This study was conducted in order to survey the perceptions of clinicians and diabetic patients with respect to PPG management and the current status of diabetes education.

Methods

This was a cross-sectional study involving face-to-face interviews and an open questionnaire survey conducted in Korea. A total of 300 patients and 130 clinicians completed questionnaires, which included current education status, self monitoring of blood glucose (SMBG), criteria of diagnosis and management, and perceptions relating to PPG management.

Results

While there was a significantly higher perceived need for diabetes education, the sufficiency of the current education was considered to be severely lacking. Fasting plasma glucose (FPG), PPG, and glycosylated hemoglobin (HbA1c) were all important considerations for clinicians when making a diagnosis of diabetes, although PPG was considered less important than FPG or HbA1c in the treatment of diabetes. Most clinicians and patients were aware of the importance of PPG, but actual education on the importance of PPG was not actively being delivered.

Conclusion

Our study showed that the current status of diabetes education is insufficient to meet the needs of the Korean population. A considerable gap was found to exist between awareness and what was actually taught in the current education program in regard to the importance of PPG. These results suggest that clinicians need to be more active in patient education, especially in regard to the importance of PPG.

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Kevin Cowart, Rachel Franks, Olivia Pane, Ellen Murphy, Kelly Oldziej
ADCES in Practice.2022; 10(2): 30. CrossRef
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George Dailey, Harpreet S Bajaj, Terry Dex, Melanie Groleau, William Stager, Aaron Vinik
BMJ Open Diabetes Research & Care.2019; 7(1): e000581. CrossRef
Experiences of Diabetes Education among Educators of Diabetes : a content analysis approach
Soo Jin Kang, Soo Jung Chang
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BeAM value: an indicator of the need to initiate and intensify prandial therapy in patients with type 2 diabetes mellitus receiving basal insulin
Ariel Zisman, Francienid Morales, John Stewart, Andreas Stuhr, Aleksandra Vlajnic, Rong Zhou
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Does Availability of Reliable Home Blood Glucose Data at Diabetes Appointments Improve Glycemia?
Gillian S. Boyd-Woschinko, David L. Kaiser, Michael Diefenbach, Ronald Tamler
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Diabetes Research and Clinical Practice.2013; 100: S17. CrossRef

Dietary Oleate Has Beneficial Effects on Every Step of Non-Alcoholic Fatty Liver Disease Progression in a Methionine- and Choline-Deficient Diet-Fed Animal Model: Ji Young Lee, Jae Hoon Moon, Jong Suk Park, Byung-Wan Lee, Eun Seok Kang, Chul Woo Ahn, Hyun Chul Lee, Bong Soo Cha; Diabetes Metab J. 2011;35(5):489-496. Published online October 31, 2011; DOI: https://doi.org/10.4093/dmj.2011.35.5.489

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Background

Non-alcoholic fatty liver disease (NAFLD) is increasingly recognized as a major cause of liver-related morbidity and mortality. The underlying mechanisms of disease progression remain poorly understood, and primary therapy of NAFLD is not yet established. We investigated the effects of dietary oleate on the development and progression of NAFLD in a methionine- and choline-deficient (MCD) diet-fed animal model.

Methods

A total of 30 C57BL/6J mice were randomly divided into three groups (n=10 in each group) and fed various experimental diets for four weeks: chow, MCD diet, or OMCD (MCD diet with oleate, 0.5 mg/g/day). Liver samples were examined for steatohepatitis and fibrosis parameters and associated genes.

Results

Additional dietary oleate dramatically reduced MCD diet-induced hepatic steatosis. Hepatic carbohydrate responsive element-binding protein was overexpressed in MCD diet-fed mice, and dietary oleate prevented this overexpression (P<0.001). Dietary oleate partially prevented MCD diet-induced serum level increases in aspartate aminotransferase and alanine aminotransferase (P<0.001, respectively). The mRNA expressions of hepatic monocyte chemoattractant protein 1, tumor necrosis factor-α and matrix metalloproteinase-9 were increased in MCD diet-fed mice, and this overexpression of inflammatory molecules was prevented by dietary oleate (P<0.001). Hepatic pericellular fibrosis was observed in MCD diet-fed mice, and dietary oleate prevented this fibrosis. Altogether, dietary oleate prevented MCD diet-induced hepatic steatosis, inflammation and fibrosis.

Conclusion

Dietary oleate has beneficial effects in every step of NAFLD development and progression and could be a nutritional option for NAFLD prevention and treatment.

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Postprandial Triglyceride Is Associated with Fasting Triglyceride and HOMA-IR in Korean Subjects with Type 2 Diabetes: Seo Hee Lee, Byung-Wan Lee, Hee Kwan Won, Jae Hoon Moon, Kwang Joon Kim, Eun Seok Kang, Bong Soo Cha, Hyun Chul Lee; Diabetes Metab J. 2011;35(4):404-410. Published online August 31, 2011; DOI: https://doi.org/10.4093/dmj.2011.35.4.404

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Background

Recent studies indicate postprandial triglyceride (TG) had a better association with cardiovascular events and metabolic syndrome than fasting TG. The authors of the present study investigated the metabolic and clinical relevance of postprandial TG.

Methods

In a cross-sectional retrospective study, the authors of the present study compared fasting and postprandial TG and analyzed the relationship between postprandial TG and various demographic and metabolic parameters in 639 Korean subjects with type 2 diabetes (T2D, group I, n=539) and impaired fasting glucose (IFG, group II, n=100) after ingestion of a standardized liquid meal (total 500 kcal, 17.5 g fat, 68.5 g carbohydrate, and 17.5 g protein).

Results

Fasting and postprandial TG were significantly correlated (r=0.973, r=0.937, P<0.001) in group I and II, respectively. Of the variables, total cholesterol, waist circumference and body mass index were significantly correlated with fasting and postprandial TG in both groups. Only postprandial TG showed a significant correlation with glucose metabolic parameters (e.g., postprandial glucose, homeostatic model assessment of insulin resistance [HOMA-IR], and fasting C-peptide) in subjects with T2D. Multiple regression analysis showed fasting TG and HOMA-IR could be predictable variables for postprandial TG in subjects with T2D.

Conclusion

Postprandial TG was very strongly correlated with fasting TG. The authors of the present study suggest insulin resistance may be more associated with postprandial TG than fasting TG in Korean T2D patients on a low-fat diet.

Citations

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