Skip Navigation
Skip to contents

Diabetes Metab J : Diabetes & Metabolism Journal

Search
OPEN ACCESS

Search

Page Path
HOME > Search
1 "Bandit Thinkhamrop"
Filter
Filter
Article category
Keywords
Publication year
Authors
Original Article
Epidemiology
The Association between Hypertension Comorbidity and Microvascular Complications in Type 2 Diabetes Patients: A Nationwide Cross-Sectional Study in Thailand
Cameron Hurst, Bandit Thinkhamrop, Hoang The Tran
Diabetes Metab J. 2015;39(5):395-404.   Published online October 22, 2015
DOI: https://doi.org/10.4093/dmj.2015.39.5.395
  • 3,872 View
  • 49 Download
  • 28 Web of Science
  • 24 Crossref
AbstractAbstract PDFPubReader   
Background

Type 2 diabetes mellitus (T2DM) is a global pandemic and its prevalence is rapidly increasing in developing countries, including Thailand. The most common comorbidity of T2DM is hypertension. T2DM with a hypertension comorbidity is likely to exacerbate the development of, or more severe microvascular complications. This study aims to determine the association between the hypertension comorbidity and microvascular complication among T2DM patients in Thailand.

Methods

The present study is a nationwide, multicenter, cross-sectional survey of T2DM outpatients across Thailand. Binary logistic mixed effect regression was used to investigate the effect of hypertension and other risk factors on the presence of microvascular complications. Imputation was used to investigate potential bias introduced by missing values.

Results

Of the 55,797 T2DM patients included in our sample, 55.35% were hypertensive. Prevalence of microvascular complication diagnosis in the last 12 months was higher in T2DM patients with hypertension than those without hypertension (12.12% vs. 9.80%, respectively). Patient with a hypertension comorbidity had 1.32 time the odds of developing microvascular complication (adjusted odds ratio [OR], 1.32; 95% confidence interval [CI], 1.20 to 1.46; P<0.001). Older age, longer diabetes duration had 1.07 and 1.21 times the odds of developing microvascular complication, per 10 years (age) and 5 years (duration), respectively (ORage, 1.07; 95% CI, 1.03 to 1.12; P<0.001; and ORduration, 1.12; 95% CI, 1.07 to 1.16; P<0.001; respectively). Minimal bias was introduced by missing values, and did not influence to the magnitude of effect of hypertension on the presence microvascular complication.

Conclusion

Hypertension comorbidity is highly associated with microvascular complication among T2DM patients. Patients with T2DM and physicians should pay attention to blood pressure control.

Citations

Citations to this article as recorded by  
  • Predictors of microvascular complications in patients with type 2 diabetes mellitus at regional referral hospitals in the central zone, Tanzania: a cross-sectional study
    Wilfred B. Shillah, James J. Yahaya, Emmanuel D. Morgan, Deogratius Bintabara
    Scientific Reports.2024;[Epub]     CrossRef
  • Trajectories of Body Mass Index and Risk for Diabetes Complications and All-Cause Mortality in Finnish Type 2 Diabetes Patients
    Zhiting Wang, Piia Lavikainen, Katja Wikström, Tiina Laatikainen
    Clinical Epidemiology.2024; Volume 16: 203.     CrossRef
  • Association between TCF7L2 polymorphism and type 2 diabetes mellitus susceptibility: a case–control study among the Bangladeshi population
    Asma Salauddin, Kallyan Chakma, Md. Mahbub Hasan, Farhana Akter, Nowshad Asgar Chowdhury, Sumon Rahman Chowdhury, Adnan Mannan
    Molecular Biology Reports.2023; 50(1): 609.     CrossRef
  • Virtual screening for chemical analogues similar to phytochemicals that inhibit aldose reductase in the development of diabetic microvascular complications
    Filex Otieno, Richard Kagia
    F1000Research.2023; 12: 314.     CrossRef
  • Effect of patient characteristics on the efficacy and safety of imeglimin monotherapy in Japanese patients with type 2 diabetes mellitus: A post‐hoc analysis of two randomized, placebo‐controlled trials
    Katsuhiko Hagi, Kenji Kochi, Hirotaka Watada, Kohei Kaku, Kohjiro Ueki
    Journal of Diabetes Investigation.2023; 14(9): 1101.     CrossRef
  • A FRAMEWORK FOR THE ANALYSIS OF COMORBID CONDITIONS USING INTELLIGENT EXTRACTION OF MULTIPLE FLUID BIOMARKERS
    PRIYANKA JADHAV, VINOTHINI SELVARAJU, SARITH P SATHIAN, RAMAKRISHNAN SWAMINATHAN
    Journal of Mechanics in Medicine and Biology.2023;[Epub]     CrossRef
  • Determinants of Hypertension Among Patients with Diabetes mellitus in Public Hospitals of Kembata Tambaro Zone, South Nations Nationalities and Peoples Region, Ethiopia, 2021; A Case Control Study
    Yeshialem Kenore, Solomon Abrha, Amanuel Yosef, Temesgen Bati Gelgelu
    Journal of Multidisciplinary Healthcare.2022; Volume 15: 2141.     CrossRef
  • The Magnitude of Diabetes Mellitus in Adult Hypertensive Patients in Northeast Ethiopia
    Mekuriaw Wuhib Shumye, Belachew Tegegne, Sewunet Ademe, Moges Workneh, Million Abera, Gugsa Nemera, Fikadu Balcha
    Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy.2021; Volume 14: 37.     CrossRef
  • Association of Combined TCF7L2 and KCNQ1 Gene Polymorphisms with Diabetic Micro- and Macrovascular Complications in Type 2 Diabetes Mellitus
    Rujikorn Rattanatham, Nongnuch Settasatian, Nantarat Komanasin, Upa Kukongviriyapan, Kittisak Sawanyawisuth, Phongsak Intharaphet, Vichai Senthong, Chatri Settasatian
    Diabetes & Metabolism Journal.2021; 45(4): 578.     CrossRef
  • Determinants of hypertension among patients with type 2 diabetes mellitus on follow-up at Tikur Anbessa Specialized Hospital, Addis Ababa: A case-control study
    Kehabtimer Shiferaw Kotiso, Nabiha Degemu, Samson Gebremedhin, Melaku Taye, Adane Petros, Fanuel Belayneh, Deneke Wolde, Dejene Hailu, Yoshihiro Fukumoto
    PLOS ONE.2021; 16(8): e0256399.     CrossRef
  • Blood Pressure and Cardiovascular Disease in Older Patients With Diabetes: Retrospective Cohort Study
    Sangmo Hong, Jung Hwan Park, Kyungdo Han, Chang Beom Lee, Dong Sun Kim, Sung Hoon Yu
    Journal of the American Heart Association.2021;[Epub]     CrossRef
  • The role of text messaging intervention in Inner Mongolia among patients with type 2 diabetes mellitus: a randomized controlled trial
    Xuemei Wang, Dan Liu, Maolin Du, Ruiqi Hao, Huiqiu Zheng, Chaoli Yan
    BMC Medical Informatics and Decision Making.2020;[Epub]     CrossRef
  • Nomogram for the prediction of diabetic nephropathy risk among patients with type 2 diabetes mellitus based on a questionnaire and biochemical indicators: a retrospective study
    Yuhong Hu, Rong Shi, Ruohui Mo, Fan Hu
    Aging.2020; 12(11): 10317.     CrossRef
  • Magnitude and determinants of drug therapy problems among type 2 diabetes mellitus patients with hypertension in Ethiopia
    Belayneh Kefale, Gobezie T Tegegne, Yitayih Kefale, Mulugeta Molla, Amien Ewunetei, Amsalu Degu
    SAGE Open Medicine.2020; 8: 205031212095469.     CrossRef
  • Angiotensin-converting enzyme 2, the complement system, the kallikrein-kinin system, type-2 diabetes, interleukin-6, and their interactions regarding the complex COVID-19 pathophysiological crossroads
    Martijn Hoevenaar, Dolf Goossens, Janne Roorda
    Journal of the Renin-Angiotensin-Aldosterone System.2020; 21(4): 147032032097909.     CrossRef
  • Impact of diabetes self-management, diabetes management self-efficacy and diabetes knowledge on glycemic control in people with Type 2 Diabetes (T2D): A multi-center study in Thailand
    Cameron P. Hurst, Nitchamon Rakkapao, Karen Hay, Chung-Ying Lin
    PLOS ONE.2020; 15(12): e0244692.     CrossRef
  • An evaluation of the impact of aggressive hypertension, diabetes and smoking cessation management on CVD outcomes at the population level: a dynamic simulation analysis
    John Pastor Ansah, Ryan Leung Hoe Inn, Salman Ahmad
    BMC Public Health.2019;[Epub]     CrossRef
  • Association between socioeconomic status and prevalence of non-communicable diseases risk factors and comorbidities in Bangladesh: findings from a nationwide cross-sectional survey
    Tuhin Biswas, Nick Townsend, Md Saimul Islam, Md Rajibul Islam, Rajat Das Gupta, Sumon Kumar Das, Abdullah Al Mamun
    BMJ Open.2019; 9(3): e025538.     CrossRef
  • Risk factors for diabetic nephropathy complications in community patients with type 2 diabetes mellitus in Shanghai: Logistic regression and classification tree model analysis
    Jieqiong Lou, Limei Jing, Hui Yang, Fei Qin, Wen Long, Rong Shi
    The International Journal of Health Planning and Management.2019; 34(3): 1013.     CrossRef
  • Retinopathy among Chinese subjects with type 2 diabetes mellitus in Shanghai: A community‐based follow‐up study
    Fei Qin, Limei Jing, Lili Jia, Jieqiong Lou, Yi Feng, Wen Long, Hui Yang, Rong Shi
    The International Journal of Health Planning and Management.2019; 34(3): 998.     CrossRef
  • Prevalence of Microvascular Complications in Type 2 Diabetics Attending a Primary Healthcare Centre in Sudan
    Mustafa Hussein, Sami Menasri
    Dubai Diabetes and Endocrinology Journal.2019; 25(3-4): 127.     CrossRef
  • Assessment of drug related problems among type 2 diabetes mellitus patients with hypertension in Hiwot Fana Specialized University Hospital, Harar, Eastern Ethiopia
    Yohanes Ayele, Kibkab Melaku, Mesay Dechasa, Mohammed Biset Ayalew, Boressa Adugna Horsa
    BMC Research Notes.2018;[Epub]     CrossRef
  • Neurosurgical position causes peripheral nerve injuries?
    Pedro Esquivel-Enríquez, Iván Pérez-Neri, Luisa Manrique-Carmona
    Cirugía y Cirujanos (English Edition).2017; 85(6): 493.     CrossRef
  • ¿La posición neuroquirúrgica ocasiona lesión de nervio periférico?
    Pedro Esquivel-Enríquez, Iván Pérez-Neri, Luisa Manrique-Carmona
    Cirugía y Cirujanos.2017; 85(6): 493.     CrossRef

Diabetes Metab J : Diabetes & Metabolism Journal
Close layer