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Sung Wan Kim  (Kim SW) 1 Article
Polymeric Gene Delivery for Diabetic Treatment
Sung Wan Kim
Diabetes Metab J. 2011;35(4):317-326.   Published online August 31, 2011
DOI: https://doi.org/10.4093/dmj.2011.35.4.317
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AbstractAbstract PDFPubReader   

Several polymers were used to delivery genes to diabetic animals. Polyaminobutyl glycolic acid was utilized to deliver IL-10 plasmid DNA to prevent autoimmune insulitis of non-obese diabetic (NOD) mouse. Polyethylene glycol grafted polylysine was combined with antisense glutamic acid decarboxylase (GAD) MRNA to represent GAD autoantigene expression. GLP1 and TSTA (SP-EX4) were delivered by bioreducible polymer to stop diabetic progression. Fas siRNA delivery was carried out to treat diabetic NOD mice animal.

Citations

Citations to this article as recorded by  
  • Delivery of therapeutic agents and cells to pancreatic islets: Towards a new era in the treatment of diabetes
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    Molecular Aspects of Medicine.2022; 83: 101063.     CrossRef
  • Applying emerging technologies to improve diabetes treatment
    Yu Jiaojiao, Caifeng Sun, Yuli Wei, Chaoying Wang, Brijesh Dave, Fei Cao, Hu Liandong
    Biomedicine & Pharmacotherapy.2018; 108: 1225.     CrossRef
  • Supercritical Fluid-Assisted Decoration of Nanoparticles on Porous Microcontainers for Codelivery of Therapeutics and Inhalation Therapy of Diabetes
    Ranjith Kumar Kankala, Xiao-Fen Lin, Hu-Fan Song, Shi-Bin Wang, Da-Yun Yang, Yu Shrike Zhang, Ai-Zheng Chen
    ACS Biomaterials Science & Engineering.2018; 4(12): 4225.     CrossRef
  • Glucose‐Responsive Supramolecular Vesicles Based on Water‐Soluble Pillar[5]arene and Pyridylboronic Acid Derivatives for Controlled Insulin Delivery
    Lei Gao, Tingting Wang, Keke Jia, Xuan Wu, Chenhao Yao, Wei Shao, Dongmei Zhang, Xiao‐Yu Hu, Leyong Wang
    Chemistry – A European Journal.2017; 23(27): 6605.     CrossRef
  • Simultaneous expression and transportation of insulin by supramolecular polysaccharide nanocluster
    Yu-Hui Zhang, Ying-Ming Zhang, Qi-Hui Zhao, Yu Liu
    Scientific Reports.2016;[Epub]     CrossRef
  • Bioreducible polymers for therapeutic gene delivery
    Young Sook Lee, Sung Wan Kim
    Journal of Controlled Release.2014; 190: 424.     CrossRef
  • Double-strand adeno-associated virus-mediated exendin-4 expression in salivary glands is efficient in a diabetic rat model
    Junhong Wang, Feng Wang, Jing Xu, Shimei Ding, Yonghong Guo
    Diabetes Research and Clinical Practice.2014; 103(3): 466.     CrossRef
  • Polymer-Based Delivery of Glucagon-Like Peptide-1 for the Treatment of Diabetes
    Pyung-Hwan Kim, Sung Wan Kim
    ISRN ENDOCRINOLOGY.2012; 2012: 1.     CrossRef
  • High serum ferritin levels are associated with metabolic risk factors in non‐obese Korean young adults: Korean National Health and Nutrition Examination Survey (KNHANES) IV
    Ki‐Dong Yoo, Seung‐Hyun Ko, Ji‐Eun Park, Yu‐Bae Ahn, Hyeon Woo Yim, Won‐Chul Lee, Yong‐Moon Park
    Clinical Endocrinology.2012; 77(2): 233.     CrossRef
  • Delivery of two-step transcription amplification exendin-4 plasmid system with arginine-grafted bioreducible polymer in type 2 diabetes animal model
    Pyung-Hwan Kim, Minhyung Lee, Sung Wan Kim
    Journal of Controlled Release.2012; 162(1): 9.     CrossRef
  • Polymeric delivery of therapeutic RAE-1 plasmid to the pancreatic islets for the prevention of type 1 diabetes
    Wan Seok Joo, Ji Hoon Jeong, Kihoon Nam, Katherine S. Blevins, Mohamed E. Salama, Sung Wan Kim
    Journal of Controlled Release.2012; 162(3): 606.     CrossRef

Diabetes Metab J : Diabetes & Metabolism Journal