Brown fat is a specialized fat depot that can increase energy expenditure and produce heat. After the recent discovery of the presence of active brown fat in human adults and novel transcription factors controlling brown adipocyte differentiation, the field of the study of brown fat has gained great interest and is rapidly growing. Brown fat expansion and/or activation results in increased energy expenditure and a negative energy balance in mice and limits weight gain. Brown fat is also able to utilize blood glucose and lipid and results in improved glucose metabolism and blood lipid independent of weight loss. Prolonged cold exposure and beta adrenergic agonists can induce browning of white adipose tissue. The inducible brown adipocyte, beige adipocyte evolving by thermogenic activation of white adipose tissue have different origin and molecular signature from classical brown adipocytes but share the characteristics of high mitochondria content, UCP1 expression and thermogenic capacity when activated. Increasing browning may also be an efficient way to increase whole brown fat activity. Recent human studies have shown possibilities that findings in mice can be reproduced in human, making brown fat a good candidate organ to treat obesity and its related disorders.

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Citations to this article as recorded by  

• 4-hydroxybenzoic acid induces browning of white adipose tissue through the AMPK-DRP1 pathway in HFD-induced obese mice
  Sang Hee Kim, Woo Yong Park, Gahee Song, Ja Yeon Park, Se Jin Jung, Kwang Seok Ahn, Jae-Young Um
  Phytomedicine.2025; 137: 156353.     CrossRef
• Wu-Mei-Wan enhances brown adipose tissue function and white adipose browning in obese mice via upregulation of HSF1
  Shen Chen, Kexin Nie, Hongzhan Wang, Yang Gao, Xinyue Jiang, Hao Su, Zhi Wang, Yueheng Tang, Fuer Lu, Hui Dong, Jingbin Li
  Chinese Medicine.2025;[Epub]     CrossRef
• Modulation of angiogenic switch in reprogramming browning and lipid metabolism in white adipocytes
  Sreelekshmi Sreekumar, Karyath Palliyath Gangaraj, Manikantan Syamala Kiran
  Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids.2024; 1869(1): 159423.     CrossRef
• Anti-Obesity Effects of GABA in C57BL/6J Mice with High-Fat Diet-Induced Obesity and 3T3-L1 Adipocytes
  Heegu Jin, Hyein Han, Gunju Song, Hyun-Ji Oh, Boo-Yong Lee
  International Journal of Molecular Sciences.2024; 25(2): 995.     CrossRef
• Citrus aurantium L. and synephrine improve brown adipose tissue function in adolescent mice programmed by early postnatal overfeeding
  Andressa Cardoso Guimarães, Egberto Gaspar de Moura, Stephanie Giannini Silva, Bruna Pereira Lopes, Iala Milene Bertasso, Carla Bruna Pietrobon, Fernanda Torres Quitete, Tayanne de Oliveira Malafaia, Érica Patrícia Garcia Souza, Patrícia Cristina Lisboa,
  Frontiers in Nutrition.2024;[Epub]     CrossRef
• Au@16-pH-16/miR-21 mimic nanosystem: An efficient treatment for obesity through browning and thermogenesis induction
  Said Lhamyani, Adriana-Mariel Gentile, María Mengual-Mesa, Elia Grueso, Rosa M. Giráldez-Pérez, José Carlos Fernandez-Garcia, Antonio Vega-Rioja, Mercedes Clemente-Postigo, John R. Pearson, Isabel González-Mariscal, Gabriel Olveira, Francisco-Javier Bermu
  Biomedicine & Pharmacotherapy.2024; 171: 116104.     CrossRef
• Walnut supplementation increases levels of UCP1 and CD36 in brown adipose tissue independently of diet type
  Tamara Dakic, Dusan Jeremic, Iva Lakic, Nebojsa Jasnic, Aleksandra Ruzicic, Predrag Vujovic, Tanja Jevdjovic
  Molecular and Cellular Biochemistry.2024; 479(7): 1735.     CrossRef
• Role of micro‐RNAs associated with adipose‐derived extracellular vesicles in metabolic disorders
  Thomas Payet, Elisa Gabinaud, Jean‐François Landrier, Lourdes Mounien
  Obesity Reviews.2024;[Epub]     CrossRef
• Spexin ameliorated obesity-related metabolic disorders through promoting white adipose browning mediated by JAK2-STAT3 pathway
  Bihe Zeng, Qin Shen, Bo Wang, Xuan Tang, Jiaqi Jiang, Yiming Zheng, Hongbiao Huang, Wenyu Zhuo, Wang Wang, Yang Gao, Xuan Li, Shuhui Wang, Wenjie Li, Guanghui Qian, Jie Qin, Miao Hou, Haitao Lv
  Nutrition & Metabolism.2024;[Epub]     CrossRef
• Genipin improves obesity through promoting bile secretion and changing bile acids composition in diet-induced obese rats
  Lili Guan, Lei Zhang, Dezheng Gong, Pengcheng Li, Shengnan Zhu, Jiulan Tang, Man Du, Maokun Zhang, Yuan Zou
  Journal of Pharmacy and Pharmacology.2024; 76(7): 897.     CrossRef
• Development of Recombinant High-Density Lipoprotein Platform with Innate Adipose Tissue-Targeting Abilities for Regional Fat Reduction
  Junhua Han, Yingxian Chen, Xiaolong Xu, Qingmeng Li, Xin Xiang, Jianzhong Shen, Xiaowei Ma
  ACS Nano.2024; 18(21): 13635.     CrossRef
• Neuronostatin regulates proliferation and differentiation of rat brown primary preadipocytes
  Małgorzata Krążek, Tatiana Wojciechowicz, Joanna Fiedorowicz, Mathias Z. Strowski, Krzysztof W. Nowak, Marek Skrzypski
  FEBS Letters.2024; 598(16): 1996.     CrossRef
• UV Irradiation Increases Appetite and Prevents Body Weight Gain through the Upregulation of Norepinephrine in Mice
  Qing-Ling Quan, Eun Ju Kim, Sungsoo Kim, Yeon Kyung Kim, Min Hwa Chung, Yu-Dan Tian, Chang-Yup Shin, Dong Hun Lee, Jin Ho Chung
  Journal of Investigative Dermatology.2024; 144(10): 2273.     CrossRef
• Polyelectrolyte nanofilms on cell surface can induce brown adipogenic differentiation of DFATs
  Aslı Sena Karanfil, Fiona Louis, Yoshihiro Sowa, Michiya Matsusaki
  Biochemical and Biophysical Research Communications.2024; 733: 150432.     CrossRef
• Dopamine in the regulation of glucose and lipid metabolism: a narrative review
  Zhehong Li, Lifei Zheng, Jing Wang, Liang Wang, Yao Qi, Buhe Amin, Jinxia Zhu, Nengwei Zhang
  Obesity.2024; 32(9): 1632.     CrossRef
• Taraxacum Mongolicum Polysaccharides Reverses Mice Obesity via Activation of AKT/mTOR Pathway
  Xiaoyu Yue, Shilong Yu, Yue Luan, Jianpeng Wang, Junxing Zhao, Mu Zhang, Qin Wang
  Nutrients.2024; 16(19): 3330.     CrossRef
• Nicotinamide Riboside Ameliorates Fructose-Induced Lipid Metabolism Disorders in Mice by Activating Browning of WAT, and May Be Also Related to the Regulation of Gut Microbiota
  Huaqi Zhang, Xuenuo Zhao, Li Zhang, Dan Sun, Yanzhen Ma, Yixian Bai, Xue Bai, Xi Liang, Hui Liang
  Nutrients.2024; 16(22): 3920.     CrossRef
• Effects of Capsicum Oleoresin on the Energy Expenditure and Mitochondrial Content of Brown Adipose Tissue in Mice Fed a High-Fat Diet
  Mak-Soon Lee, Miae Doo, In-Hwan Kim, Yangha Kim
  Preventive Nutrition and Food Science.2024; 29(4): 422.     CrossRef
• A Newly Synbiotic Combination Alleviates Obesity by Modulating the Gut Microbiota–Fat Axis and Inhibiting the Hepatic TLR4/NF‐κB Signaling Pathway
  Yongbo Kang, Peng Ren, Xiaorong Shen, Xiaoyu Kuang, Xiaodan Yang, Haixia Liu, Huan Yan, Hao Yang, Xing Kang, Zeyuan Ding, Xuguang Luo, Jieqiong Ma, Ying Yang, Weiping Fan
  Molecular Nutrition & Food Research.2023;[Epub]     CrossRef
• Lacticaseibacillus paracasei AO356 ameliorates obesity by regulating adipogenesis and thermogenesis in C57BL/6J male mice
  Young In Kim, Eun-Sook Lee, Eun-Ji Song, Dong-Uk Shin, Ji-Eun Eom, Hee Soon Shin, Jung Eun Kim, Ju Yeoun Oh, Young-Do Nam, So-Young Lee
  Journal of Functional Foods.2023; 101: 105404.     CrossRef
• Effects of caffeoylquinic acid analogs derived from aerial parts of Artemisia iwayomogi on adipogenesis
  Su-Young Han, Jisu Kim, Bo Kyeong Kim, Wan Kyunn Whang, Hyeyoung Min
  Food Science and Biotechnology.2023; 32(9): 1215.     CrossRef
• Anti-obesity effects of Lactiplantibacillus plantarum SKO-001 in high-fat diet-induced obese mice
  Mi Jin Choi, Hana Yu, Jea Il Kim, Hee Seo, Ju Gyeong Kim, Seul-Ki Kim, Hak Sung Lee, Hyae Gyeong Cheon
  European Journal of Nutrition.2023; 62(4): 1611.     CrossRef
• Meteorin-like Protein and Asprosin Levels in Children and Adolescents with Obesity and Their Relationship with Insulin Resistance and Metabolic Syndrome
  Nariman Moradi, Reza Fadaei, Maryam Roozbehkia, Mitra Nourbakhsh, Mona Nourbakhsh, Maryam Razzaghy-Azar, Bagher Larijani
  Laboratory Medicine.2023; 54(5): 457.     CrossRef
• A Novel Mix of Polyphenols and Micronutrients Reduces Adipogenesis and Promotes White Adipose Tissue Browning via UCP1 Expression and AMPK Activation
  Francesca Pacifici, Gina Malatesta, Caterina Mammi, Donatella Pastore, Vincenzo Marzolla, Camillo Ricordi, Francesca Chiereghin, Marco Infante, Giulia Donadel, Francesco Curcio, Annalisa Noce, Valentina Rovella, Davide Lauro, Manfredi Tesauro, Nicola Di D
  Cells.2023; 12(5): 714.     CrossRef
• Thromboxane A2-TP axis promotes adipose tissue macrophages M1 polarization leading to insulin resistance in obesity
  Ruijie Xu, Yufeng Dai, Xu Zheng, Yongheng Yan, Zhao He, Hao Zhang, Haitao Li, Wei Chen
  Biochemical Pharmacology.2023; 210: 115465.     CrossRef
• Green Tea Epigallocatechin Gallate Inhibits Preadipocyte Growth via the microRNA‐let‐7a/HMGA2 Signaling Pathway
  Wen‐Ting Chen, Meei‐Ju Yang, Yi‐Wei Tsuei, Tsung‐Chen Su, An‐Ci Siao, Yow‐Chii Kuo, Ling‐Ru Huang, Yi Chen, Sy‐Jou Chen, Po‐Chuan Chen, Ching‐Feng Cheng, Hui‐Chen Ku, Yung‐Hsi Kao
  Molecular Nutrition & Food Research.2023;[Epub]     CrossRef
• Current Role and Potential of Polymeric Biomaterials in Clinical Obesity Treatment
  Rui-Chian Tang, I-Hsuan Yang, Feng-Huei Lin
  Biomacromolecules.2023; 24(8): 3438.     CrossRef
• Short-duration cold exposure decreases fasting-induced glucose intolerance but has no effect on resting energy expenditure
  Rima Solianik, Katerina Židonienė, Marius Brazaitis
  Cryobiology.2023; 113: 104564.     CrossRef
• Caffeine promotes the production of Irisin in muscles and thus facilitates the browning of white adipose tissue
  Chang Liu, Yi Li, Ge Song, Xuehan Li, Songyue Chen, Dixin Zou, Huixin Li, Chengyi Hu, Haotian Zhao, Yi Yan
  Journal of Functional Foods.2023; 108: 105702.     CrossRef
• Thermogenic Modulation of Adipose Depots: A Perspective on Possible Therapeutic Intervention with Early Cardiorenal Complications of Metabolic Impairment
  Ahmed F. El-Yazbi, Mohamed A. Elrewiny, Hosam M. Habib, Ali H. Eid, Perihan A. Elzahhar, Ahmed S.F. Belal
  Molecular Pharmacology.2023; 104(5): 187.     CrossRef
• Rabbit Meat Extract Induces Browning in 3T3−L1 Adipocytes via the AMP−Activated Protein Kinase Pathway
  In-Seon Bae, Jeong Ah Lee, Soo-Hyun Cho, Hyoun-Wook Kim, Yunseok Kim, Kangmin Seo, Hyun-Woo Cho, Min Young Lee, Ju Lan Chun, Ki Hyun Kim
  Foods.2023; 12(19): 3671.     CrossRef
• Metabolic-Dysfunction-Associated Steatotic Liver Disease—Its Pathophysiology, Association with Atherosclerosis and Cardiovascular Disease, and Treatments
  Hidekatsu Yanai, Hiroki Adachi, Mariko Hakoshima, Sakura Iida, Hisayuki Katsuyama
  International Journal of Molecular Sciences.2023; 24(20): 15473.     CrossRef
• Brown Fat and Nutrition: Implications for Nutritional Interventions
  Lloyd Noriega, Cheng-Ying Yang, Chih-Hao Wang
  Nutrients.2023; 15(18): 4072.     CrossRef
• Metabolic Syndrome: A Narrative Review from the Oxidative Stress to the Management of Related Diseases
  Giovanni Martemucci, Giuseppe Fracchiolla, Marilena Muraglia, Roberta Tardugno, Roberta Savina Dibenedetto, Angela Gabriella D’Alessandro
  Antioxidants.2023; 12(12): 2091.     CrossRef
• Metabolic responses of light and taste receptors – unexpected actions of GPCRs in adipocytes
  Onyinye Nuella Ekechukwu, Mark Christian
  Reviews in Endocrine and Metabolic Disorders.2022; 23(1): 111.     CrossRef
• The ATF3 inducer protects against diet-induced obesity via suppressing adipocyte adipogenesis and promoting lipolysis and browning
  Hui-Chen Ku, Tsai-Yun Chan, Jia-Fang Chung, Yung-Hsi Kao, Ching-Feng Cheng
  Biomedicine & Pharmacotherapy.2022; 145: 112440.     CrossRef
• Prednisone stimulates white adipocyte browning via β3-AR/p38 MAPK/ERK signaling pathway
  Sulagna Mukherjee, Jong Won Yun
  Life Sciences.2022; 288: 120204.     CrossRef
• Tangeretin prevents obesity by modulating systemic inflammation, fat browning, and gut microbiota in high-fat diet-induced obese C57BL/6 mice
  Qiyang Chen, Dan Wang, Yue Gu, Zixiao Jiang, Zhiqin Zhou
  The Journal of Nutritional Biochemistry.2022; 101: 108943.     CrossRef
• Evaluation of thermal sensitivity is of potential clinical utility for the predictive, preventive, and personalized approach advancing metabolic syndrome management
  Sujeong Mun, Kihyun Park, Siwoo Lee
  EPMA Journal.2022; 13(1): 125.     CrossRef
• Effects of a Novel Selective Peroxisome Proliferator-Activated Receptor α Modulator, Pemafibrate, on Metabolic Parameters: A Retrospective Longitudinal Study
  Hidekatsu Yanai, Hisayuki Katsuyama, Mariko Hakoshima
  Biomedicines.2022; 10(2): 401.     CrossRef
• Historical and cultural aspects of obesity: From a symbol of wealth and prosperity to the epidemic of the 21st century
  Marta Sumińska, Rafał Podgórski, Klaudia Bogusz‐Górna, Bogda Skowrońska, Artur Mazur, Marta Fichna
  Obesity Reviews.2022;[Epub]     CrossRef
• Molecular Biological and Clinical Understanding of the Statin Residual Cardiovascular Disease Risk and Peroxisome Proliferator-Activated Receptor Alpha Agonists and Ezetimibe for Its Treatment
  Hidekatsu Yanai, Hiroki Adachi, Mariko Hakoshima, Hisayuki Katsuyama
  International Journal of Molecular Sciences.2022; 23(7): 3418.     CrossRef
• Pep19 Has a Positive Effect on Insulin Sensitivity and Ameliorates Both Hepatic and Adipose Tissue Phenotype of Diet-Induced Obese Mice
  Renata Silvério, Robson Barth, Andrea S. Heimann, Patrícia Reckziegel, Gustavo J. dos Santos, Silvana Y. Romero-Zerbo, Francisco J. Bermúdez-Silva, Alex Rafacho, Emer S. Ferro
  International Journal of Molecular Sciences.2022; 23(8): 4082.     CrossRef
• Thermogenic T cells: a cell therapy for obesity?
  Ulf H. Beier, Daniel J. Baker, Joseph A. Baur
  American Journal of Physiology-Cell Physiology.2022; 322(6): C1085.     CrossRef
• Accumulation of γδ T cells in visceral fat with aging promotes chronic inflammation
  Maria E. C. Bruno, Sujata Mukherjee, Whitney L. Powell, Stephanie F. Mori, Franklyn K. Wallace, Beverly K. Balasuriya, Leon C. Su, Arnold J. Stromberg, Donald A. Cohen, Marlene E. Starr
  GeroScience.2022; 44(3): 1761.     CrossRef
• Deletion of GPR30 Drives the Activation of Mitochondrial Uncoupling Respiration to Induce Adipose Thermogenesis in Female Mice
  Jing Luo, Yao Wang, Elizabeth Gilbert, Dongmin Liu
  Frontiers in Endocrinology.2022;[Epub]     CrossRef
• Inhibition of STAT3 enhances UCP1 expression and mitochondrial function in brown adipocytes
  Lini Song, Xi Cao, Wenyi Ji, Lili Zhao, Weili Yang, Ming Lu, Jinkui Yang
  European Journal of Pharmacology.2022; 926: 175040.     CrossRef
• TRPC5 deletion in the central amygdala antagonizes high-fat diet-induced obesity by increasing sympathetic innervation
  Huan Ma, Chengkang He, Li Li, Peng Gao, Zongshi Lu, Yingru Hu, Lijuan Wang, Yu Zhao, Tingbing Cao, Yuanting Cui, Hongting Zheng, Gangyi Yang, Zhencheng Yan, Daoyan Liu, Zhiming Zhu
  International Journal of Obesity.2022; 46(8): 1544.     CrossRef
• Adapalene induces adipose browning through the RARβ-p38 MAPK-ATF2 pathway
  Na Hyun Lee, Mi Jin Choi, Hana Yu, Jea Il Kim, Hyae Gyeong Cheon
  Archives of Pharmacal Research.2022; 45(5): 340.     CrossRef
• Engineering Functional Vascularized Beige Adipose Tissue from Microvascular Fragments of Models of Healthy and Type II Diabetes Conditions
  Francisca M. Acosta, Katerina Stojkova, Jingruo Zhang, Eric Ivan Garcia Huitron, Jean X. Jiang, Christopher R. Rathbone, Eric M. Brey
  Journal of Tissue Engineering.2022;[Epub]     CrossRef
• Atractylenolide III from Atractylodes macrocephala Koidz promotes the activation of brown and white adipose tissue through SIRT1/PGC-1α signaling pathway
  Xin Liu, Yuan Huang, Xu Liang, Qiong Wu, Nan Wang, Li-jun Zhou, Wen-wu Liu, Qun Ma, Bei Hu, Huan Gao, Ya-ling Cui, Xiang Li, Qing-chun Zhao
  Phytomedicine.2022; 104: 154289.     CrossRef
• The pathobiology of perivascular adipose tissue (PVAT), the fourth layer of the blood vessel wall
  Cassie Hillock-Watling, Avrum I. Gotlieb
  Cardiovascular Pathology.2022; 61: 107459.     CrossRef
• RNA-Binding Proteins in the Regulation of Adipogenesis and Adipose Function
  Pengpeng Zhang, Wenyan Wu, Chaofeng Ma, Chunyu Du, Yueru Huang, Haixia Xu, Cencen Li, Xiaofang Cheng, Ruijie Hao, Yongjie Xu
  Cells.2022; 11(15): 2357.     CrossRef
• The Effect of Swimming Training with Cinnamon Consumption on β3-AR and ERK2 Gene Expression in the Visceral Adipose Tissue of Diabetic Rats
  Kianoosh Mohammadi, Ali Khajehlandi, Amin Mohammadi
  Gene, Cell and Tissue.2022;[Epub]     CrossRef
• Of mice and men: Considerations on adipose tissue physiology in animal models of obesity and human studies
  Ioannis G. Lempesis, Dimitrios Tsilingiris, Junli Liu, Maria Dalamaga
  Metabolism Open.2022; 15: 100208.     CrossRef
• The comparison of the effect of acute moderate and high-intensity exercise on the uncoupling protein -1 secretion
  Desiana Merawati, Sugiharto Sugiharto, Adi Pranoto, Olivia Andiana, Prayogi Dwina Angga
  Jurnal SPORTIF : Jurnal Penelitian Pembelajaran.2022; 8(2): 201.     CrossRef
• Omega-3 Polyunsaturated Fatty Acids Protect against High-Fat Diet-Induced Morphological and Functional Impairments of Brown Fat in Transgenic Fat-1 Mice
  Lei Hao, Yong-Hui Nie, Chih-Yu Chen, Xiang-Yong Li, Kanakaraju Kaliannan, Jing X. Kang
  International Journal of Molecular Sciences.2022; 23(19): 11903.     CrossRef
• Modulation of hypothalamic AMPK phosphorylation by olanzapine controls energy balance and body weight
  Vitor Ferreira, Cintia Folgueira, Maria Guillén, Pablo Zubiaur, Marcos Navares, Assel Sarsenbayeva, Pilar López-Larrubia, Jan W. Eriksson, Maria J. Pereira, Francisco Abad-Santos, Guadalupe Sabio, Patricia Rada, Ángela M. Valverde
  Metabolism.2022; 137: 155335.     CrossRef
• Okra (Abelmoschus esculentusL. Moench) prevents obesity by reducing lipid accumulation and increasing white adipose browning in high-fat diet-fed mice
  Heegu Jin, Hyun-Ji Oh, Sehaeng Cho, Ok-Hwan Lee, Boo-Yong Lee
  Food & Function.2022; 13(22): 11840.     CrossRef
• Functional Attenuation of UCP1 as the Potential Mechanism for a Thickened Blubber Layer in Cetaceans
  Ming Zhou, Tianzhen Wu, Yue Chen, Shixia Xu, Guang Yang, Anne Yoder
  Molecular Biology and Evolution.2022;[Epub]     CrossRef
• Brown adipose tissue transplantation as a novel alternative to obesity treatment: a systematic review
  Moloud Payab, Mina Abedi, Najmeh Foroughi Heravani, Mahdieh Hadavandkhani, Maryam Arabi, Akram Tayanloo-Beik, Motahareh Sheikh Hosseini, Hadis Gerami, Fateme Khatami, Bagher Larijani, Mohammad Abdollahi, Babak Arjmand
  International Journal of Obesity.2021; 45(1): 109.     CrossRef
• Corylin reduces obesity and insulin resistance and promotes adipose tissue browning through SIRT-1 and β3-AR activation
  Chin-Chuan Chen, Chen-Hsin Kuo, Yann-Lii Leu, Shu-Huei Wang
  Pharmacological Research.2021; 164: 105291.     CrossRef
• Inducible beige adipocytes improve impaired glucose metabolism in interscapular BAT-removal mice
  Xiao-Wei Jia, Dong-Liang Fang, Xin-Yi Shi, Tao Lu, Chun Yang, Yan Gao
  Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids.2021; 1866(3): 158871.     CrossRef
• NNT‐induced tumor cell “slimming” reverses the pro‐carcinogenesis effect of HIF2a in tumors
  Zhiyong Xiong, Wei Xiong, Wen Xiao, Changfei Yuan, Jian Shi, Yu Huang, Cheng Wang, Xiangui Meng, Zhixian Chen, Hongmei Yang, Ke Chen, Xiaoping Zhang
  Clinical and Translational Medicine.2021;[Epub]     CrossRef
• CD10 marks non-canonical PPARγ-independent adipocyte maturation and browning potential of adipose-derived stem cells
  Smarajit Chakraborty, Wee Kiat Ong, Winifred W. Y. Yau, Zhihong Zhou, K. N. Bhanu Prakash, Sue-Anne Toh, Weiping Han, Paul M. Yen, Shigeki Sugii
  Stem Cell Research & Therapy.2021;[Epub]     CrossRef
• Regulatory roles of G-protein coupled receptors in adipose tissue metabolism and their therapeutic potential
  Hyeonyeong Im, Ji-Hyun Park, Seowoo Im, Juhyeong Han, Kyungmin Kim, Yun-Hee Lee
  Archives of Pharmacal Research.2021; 44(2): 133.     CrossRef
• 3-N-butylphthalide protects against high-fat-diet-induced obesity in C57BL/6 mice and increases metabolism in lipid-accumulating cells
  Kang-Yun Lu, Shinn-Zong Lin, Kingsley Theras Primus Dass, Wei-Ju Lin, Shih-Ping Liu, Horng-Jyh Harn
  Biomedicine & Pharmacotherapy.2021; 139: 111687.     CrossRef
• Ellagic acid induces beige remodeling of white adipose tissue by controlling mitochondrial dynamics and SIRT3
  Woo Yong Park, Jinbong Park, Kwang Seok Ahn, Hyun Jeong Kwak, Jae‐Young Um
  The FASEB Journal.2021;[Epub]     CrossRef
• Cajanolactone A, a Stilbenoid From Cajanus canjan (L.) Millsp, Prevents High-Fat Diet-Induced Obesity via Suppressing Energy Intake
  Zhuohui Luo, Jiawen Huang, Zhiping Li, Zhiwen Liu, Linchun Fu, Yingjie Hu, Xiaoling Shen
  Frontiers in Pharmacology.2021;[Epub]     CrossRef
• Zinc and the Innovative Zinc-α2-Glycoprotein Adipokine Play an Important Role in Lipid Metabolism: A Critical Review
  Michalina Banaszak, Ilona Górna, Juliusz Przysławski
  Nutrients.2021; 13(6): 2023.     CrossRef
• Natural products in the management of obesity: Fundamental mechanisms and pharmacotherapy
  Yinghan Chan, Sin Wi Ng, Joycelin Zhu Xin Tan, Gaurav Gupta, Poonam Negi, Lakshmi Thangavelu, Sri Renukadevi Balusamy, Haribalan Perumalsamy, Wei Hsum Yap, Sachin Kumar Singh, Vanni Caruso, Kamal Dua, Dinesh Kumar Chellappan
  South African Journal of Botany.2021; 143: 176.     CrossRef
• Group IIA secreted phospholipase A2 (PLA2G2A) augments adipose tissue thermogenesis
  Michael S. Kuefner, Erin Stephenson, Mladen Savikj, Heather S. Smallwood, Qingming Dong, Christine Payré, Gérard Lambeau, Edwards A. Park
  The FASEB Journal.2021;[Epub]     CrossRef
• N-butylidenephthalide ameliorates high-fat diet-induced obesity in mice and promotes browning through adrenergic response/AMPK activation in mouse beige adipocytes
  Kang-Yun Lu, Kingsley Theras Primus Dass, Shinn-Zong Lin, Yu-Hua Tseng, Shih-Ping Liu, Horng-Jyh Harn
  Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids.2021; 1866(12): 159033.     CrossRef
• Green tea aqueous extract (GTAE) prevents high‐fat diet‐induced obesity by activating fat browning
  Jie Li, Qiyang Chen, Xiuming Zhai, Dan Wang, Yujia Hou, Min Tang
  Food Science & Nutrition.2021; 9(12): 6548.     CrossRef
• Ipragliflozin, an SGLT2 Inhibitor, Ameliorates High-Fat Diet-Induced Metabolic Changes by Upregulating Energy Expenditure through Activation of the AMPK/ SIRT1 Pathway
  Ji-Yeon Lee, Minyoung Lee, Ji Young Lee, Jaehyun Bae, Eugene Shin, Yong-ho Lee, Byung-Wan Lee, Eun Seok Kang, Bong-Soo Cha
  Diabetes & Metabolism Journal.2021; 45(6): 921.     CrossRef
• The increase of uncoupling protein-1 expression after moderate intensity continuous exercises in obese females
  Sugiharto, Banih Sakti Adji, Desiana Merawati, Adi Pranoto
  Jurnal SPORTIF : Jurnal Penelitian Pembelajaran.2021; 7(2): 194.     CrossRef
• Effects of Royal Jelly and Tocotrienol Rich Fraction in obesity treatment of calorie-restricted obese rats: a focus on white fat browning properties and thermogenic capacity
  Naimeh Mesri Alamdari, Pardis Irandoost, Neda Roshanravan, Mohammadreza Vafa, Mohammad Asghari Jafarabadi, Shahriar Alipour, Leila Roshangar, Mohammadreza Alivand, Farnaz Farsi, Farzad Shidfar
  Nutrition & Metabolism.2020;[Epub]     CrossRef
• Metabolic Benefits of MicroRNA-22 Inhibition
  Marc Thibonnier, Christine Esau
  Nucleic Acid Therapeutics.2020; 30(2): 104.     CrossRef
• Grape pomace extract supplementation activates FNDC5/irisin in muscle and promotes white adipose browning in rats fed a high-fat diet
  Cecilia Rodriguez Lanzi, Diahann J. Perdicaro, Julián Gambarte Tudela, Victoria Muscia, Ariel R. Fontana, Patricia I. Oteiza, Marcela A. Vazquez Prieto
  Food & Function.2020; 11(2): 1537.     CrossRef
• Citrus aurantium L. polymethoxyflavones promote thermogenesis of brown and white adipose tissue in high-fat diet induced C57BL/6J mice
  Guangning Kou, Yan Hu, Zixiao Jiang, Zhenqing Li, Peiyuan Li, Hongjie Song, Qiyang Chen, Zhiqin Zhou, Quanjun Lyu
  Journal of Functional Foods.2020; 67: 103860.     CrossRef
• Beneficial effects of pomegranate peel extract treatment on anthropometry and body composition of overweight patients with diabetes mellitus type-2: A randomised clinical trial
  Milkica Grabež, Ranko Škrbić, Miloš Stojiljković, Vesna Rudić-Grujić, Katarina Šavikin, Nebojša Menković, Gordana Zdunić, Nađa Vasiljević
  Scripta Medica.2020; 51(1): 21.     CrossRef
• Milk fat globule membrane and its component phosphatidylcholine induce adipose browning both in vivo and in vitro
  Tiange Li, Min Du, Hanning Wang, Xueying Mao
  The Journal of Nutritional Biochemistry.2020; 81: 108372.     CrossRef
• Dynamic contrast‐enhanced MRI of brown and beige adipose tissues
  Jadegoud Yaligar, Sanjay Kumar Verma, Venkatesh Gopalan, Rengaraj Anantharaj, Giang Thi Thu Le, Kavita Kaur, Karthik Mallilankaraman, MK Leow, SS Velan
  Magnetic Resonance in Medicine.2020; 84(1): 384.     CrossRef
• Taurine Stimulates Thermoregulatory Genes in Brown Fat Tissue and Muscle without an Influence on Inguinal White Fat Tissue in a High-Fat Diet-Induced Obese Mouse Model
  Kyoung Soo Kim, Hari Madhuri Doss, Hee-Jin Kim, Hyung-In Yang
  Foods.2020; 9(6): 688.     CrossRef
• White adipose tissue browning in critical illness: A review of the evidence, mechanisms and future perspectives
  Elham Alipoor, Mohammad Javad Hosseinzadeh‐Attar, Mahsa Rezaei, Shima Jazayeri, Marianne Chapman
  Obesity Reviews.2020;[Epub]     CrossRef
• Metabolic and energetic benefits of microRNA-22 inhibition
  Marc Thibonnier, Christine Esau, Sujoy Ghosh, Edward Wargent, Claire Stocker
  BMJ Open Diabetes Research & Care.2020; 8(1): e001478.     CrossRef
• Apple polyphenols induce browning of white adipose tissue
  Yuki Tamura, Shigeto Tomiya, Junya Takegaki, Karina Kouzaki, Arata Tsutaki, Koichi Nakazato
  The Journal of Nutritional Biochemistry.2020; 77: 108299.     CrossRef
• Adipose TBX1 regulates β-adrenergic sensitivity in subcutaneous adipose tissue and thermogenic capacity in vivo
  Kathleen R. Markan, Lauren K. Boland, Abdul Qaadir King-McAlpin, Kristin E. Claflin, Michael P. Leaman, Morgan K. Kemerling, Madison M. Stonewall, Brad A. Amendt, James A. Ankrum, Matthew J. Potthoff
  Molecular Metabolism.2020; 36: 100965.     CrossRef
• A systematic review of the association of neuregulin 4, a brown fat–enriched secreted factor, with obesity and related metabolic disturbances
  Helda Tutunchi, Alireza Ostadrahimi, Mohammad‐Javad Hosseinzadeh‐Attar, Mahsa Miryan, Majid Mobasseri, Mehrangiz Ebrahimi‐Mameghani
  Obesity Reviews.2020;[Epub]     CrossRef
• Deficiency of glutathione peroxidase-1 and catalase attenuated diet-induced obesity and associated metabolic disorders
  Hyung-Ran Kim, Eun-Jeong Choi, Jeong-Hae Kie, Joo-Ho Lee, Ju-Young Seoh
  Acta Diabetologica.2020; 57(2): 151.     CrossRef
• Clinical Application Potential of Small Molecules that Induce Brown Adipose Tissue Thermogenesis by Improving Fat Metabolism
  Kang-Yun Lu, Kingsley Theras Primus Dass, Sheng-Feng Tsai, Hong-Meng Chuang, Shinn-Zong Lin, Shih-Ping Liu, Horng-Jyh Harn
  Cell Transplantation.2020; 29: 096368972092739.     CrossRef
• MiR‐92a regulates brown adipocytes differentiation, mitochondrial oxidative respiration, and heat generation by targeting SMAD7
  Zhipin Zhang, Huixin Jiang, Xiang Li, Xiaomin Chen, Yihua Huang
  Journal of Cellular Biochemistry.2020; 121(8-9): 3825.     CrossRef
• Bilirubin remodels murine white adipose tissue by reshaping mitochondrial activity and the coregulator profile of peroxisome proliferator–activated receptor α
  Darren M. Gordon, Kari L. Neifer, Abdul-Rizaq Ali Hamoud, Charles F. Hawk, Andrea L. Nestor-Kalinoski, Scott A. Miruzzi, Michael P. Morran, Samuel O. Adeosun, Jeffrey G. Sarver, Paul W. Erhardt, Robert E. McCullumsmith, David E. Stec, Terry D. Hinds
  Journal of Biological Chemistry.2020; 295(29): 9804.     CrossRef
• The Presence of Active Brown Adipose Tissue Determines Cold-Induced Energy Expenditure and Oxylipin Profiles in Humans
  Oana C Kulterer, Laura Niederstaetter, Carsten T Herz, Alexander R Haug, Andrea Bileck, Dietmar Pils, Alexandra Kautzky-Willer, Christopher Gerner, Florian W Kiefer
  The Journal of Clinical Endocrinology & Metabolism.2020; 105(7): 2203.     CrossRef
• Downregulation of osteopontin inhibits browning of white adipose tissues through PI3K-AKT pathway in C57BL / 6 mice
  Yi Lu, Yuhong Xu, Wanwan Yuan, Mengxi Wang, Yumeng Zhou, Kai Chen, Qiren Huang
  European Journal of Pharmacology.2020; 866: 172822.     CrossRef
• Angiotensin AT1 receptor antagonism by losartan stimulates adipocyte browning via induction of apelin
  Dong Young Kim, Mi Jin Choi, Tae Kyung Ko, Na Hyun Lee, Ok-Hee Kim, Hyae Gyeong Cheon
  Journal of Biological Chemistry.2020; 295(44): 14878.     CrossRef
• Isoliquiritigenin Enhances the Beige Adipocyte Potential of Adipose-Derived Stem Cells by JNK Inhibition
  Hanbyeol Moon, Jung-Won Choi, Byeong-Wook Song, Il-Kwon Kim, Soyeon Lim, Seahyoung Lee, Ki-Chul Hwang, Sang Woo Kim
  Molecules.2020; 25(23): 5660.     CrossRef
• In vitro evaluation of Hydrilla verticillata for anti-adipogenesis activity on 3T3 L1 cell lines
  SPandi Prabha, S Sadhana, C Karthik, DG Caroline
  Pharmacognosy Magazine.2020; 16(5): 498.     CrossRef
• Leptin Promotes White Adipocyte Browning by Inhibiting the Hh Signaling Pathway
  Jie Wang, Jing Ge, Haigang Cao, Xiaoyu Zhang, Yuan Guo, Xiao Li, Bo Xia, Gongshe Yang, Xin’e Shi
  Cells.2019; 8(4): 372.     CrossRef
• Impact of Gut Microbiota on Host Glycemic Control
  Céline Gérard, Hubert Vidal
  Frontiers in Endocrinology.2019;[Epub]     CrossRef
• Effect of resveratrol on adipokines and myokines involved in fat browning: Perspectives in healthy weight against obesity
  Oh Yoen Kim, Ji Yeon Chung, Juhyun Song
  Pharmacological Research.2019; 148: 104411.     CrossRef
• A comprehensive diagnostic approach to detect underlying causes of obesity in adults
  Eline S. van der Valk, Erica L.T. van den Akker, Mesut Savas, Lotte Kleinendorst, Jenny A. Visser, Mieke M. Van Haelst, Arya M. Sharma, Elisabeth F.C. van Rossum
  Obesity Reviews.2019; 20(6): 795.     CrossRef
• Prostacyclin: A major prostaglandin in the regulation of adipose tissue development
  Mohammad Sharifur Rahman
  Journal of Cellular Physiology.2019; 234(4): 3254.     CrossRef
• The expression of brown fat‐associated proteins in colorectal cancer and the relationship of uncoupling protein 1 with prognosis
  Abdo Alnabulsi, Beatriz Cash, Yehfang Hu, Linda Silina, Ayham Alnabulsi, Graeme I. Murray
  International Journal of Cancer.2019; 145(4): 1138.     CrossRef
• Garlic augments the functional and nutritional behavior of Doenjang, a traditional Korean fermented soybean paste
  Ashutosh Bahuguna, Shruti Shukla, Jong Suk Lee, Vivek K. Bajpai, So-Young Kim, Yun Suk Huh, Young-Kyu Han, Myunghee Kim
  Scientific Reports.2019;[Epub]     CrossRef
• Clomiphene promotes browning of white adipocytes via casein kinase-2 inhibition
  Hyun-Jin Kim, Dong Young Kim, Hyae Gyeong Cheon
  European Journal of Pharmacology.2019; 861: 172596.     CrossRef
• Neuroendocrine Regulation of Energy Metabolism Involving Different Types of Adipose Tissues
  Qi Zhu, Bradley J. Glazier, Benjamin C. Hinkel, Jingyi Cao, Lin Liu, Chun Liang, Haifei Shi
  International Journal of Molecular Sciences.2019; 20(11): 2707.     CrossRef
• Tumor Cell “Slimming” Regulates Tumor Progression through PLCL1/UCP1‐Mediated Lipid Browning
  Zhiyong Xiong, Wen Xiao, Lin Bao, Wei Xiong, Haibing Xiao, Yan Qu, Changfei Yuan, Hailong Ruan, Qi Cao, Keshan Wang, Zhengshuai Song, Cheng Wang, Wenjun Hu, Zeyuan Ru, Junwei Tong, Gong Cheng, Tianbo Xu, Xiangui Meng, Jian Shi, Zhixian Chen, Hongmei Yang,
  Advanced Science.2019;[Epub]     CrossRef
• Soyasaponin Ab alleviates postmenopausal obesity through browning of white adipose tissue
  Han-Jun Kim, Eun-Ji Choi, Hyo Sung Kim, Chan-Woong Choi, Sik-Won Choi, Sun-Lim Kim, Woo-Duck Seo, Sun Hee Do
  Journal of Functional Foods.2019; 57: 453.     CrossRef
• Beneficial Effects of Pomegranate Peel Extract and Probiotics on Pre-adipocyte Differentiation
  Valeria Sorrenti, Cinzia Lucia Randazzo, Cinzia Caggia, Gabriele Ballistreri, Flora Valeria Romeo, Simona Fabroni, Nicolina Timpanaro, Marco Raffaele, Luca Vanella
  Frontiers in Microbiology.2019;[Epub]     CrossRef
• Visfatin; a potential novel mediator of brown adipose tissue
  Parmida Pourvali-Talatappeh, Elham Alipoor
  Obesity Medicine.2019; 15: 100122.     CrossRef
• Strategies and methods for the correction of obesity and associated cardiovascular risk
  T. Yu. Kuznetsova, M. A. Druzhilov, G. A. Chumakova, N. D. Veselovskaya
  Russian Journal of Cardiology.2019; (4): 61.     CrossRef
• Polymeric Carriers for Controlled Drug Delivery in Obesity Treatment
  Di Huang, Meng Deng, Shihuan Kuang
  Trends in Endocrinology & Metabolism.2019; 30(12): 974.     CrossRef
• Tbx15 is required for adipocyte browning induced by adrenergic signaling pathway
  Wei Sun, Xuemei Zhao, Zhengqi Wang, Yi Chu, Liufeng Mao, Shaoqiang Lin, Xuefei Gao, Yuna Song, Xiaoyan Hui, Shiqi Jia, Shibing Tang, Yong Xu, Aimin Xu, Kerry Loomes, Cunchuan Wang, Donghai Wu, Tao Nie
  Molecular Metabolism.2019; 28: 48.     CrossRef
• Effects of caloric restriction on the expression of lipocalin-2 and its receptor in the brown adipose tissue of high-fat diet-fed mice
  Kyung-Ah Park, Zhen Jin, Hyeong Seok An, Jong Youl Lee, Eun Ae Jeong, Eun Bee Choi, Kyung Eun Kim, Hyun Joo Shin, Jung Eun Lee, Gu Seob Roh
  The Korean Journal of Physiology & Pharmacology.2019; 23(5): 335.     CrossRef
• Peripherally administered melanocortins induce mice fat browning and prevent obesity
  Adriana R. Rodrigues, Maria J. Salazar, Sílvia Rocha-Rodrigues, Inês O. Gonçalves, Célia Cruz, Delminda Neves, Henrique Almeida, José Magalhães, Alexandra M. Gouveia
  International Journal of Obesity.2019; 43(5): 1058.     CrossRef
• Chinese medicine Jinlida granules improve high-fat-diet induced metabolic disorders via activation of brown adipose tissue in mice
  Hui Zhang, Yuanyuan Hao, Cong Wei, Bing Yao, Shen Liu, Hongru Zhou, Dan Huang, Chuanhai Zhang, Yiling Wu
  Biomedicine & Pharmacotherapy.2019; 114: 108781.     CrossRef
• Effects of lobeglitazone, a novel thiazolidinedione, on adipose tissue remodeling and brown and beige adipose tissue development in db/db mice
  G Kim, Y-h Lee, M R Yun, J-Y Lee, E G Shin, B-W Lee, E S Kang, B-S Cha
  International Journal of Obesity.2018; 42(3): 542.     CrossRef
• Air Pollution Has a Significant Negative Impact on Intentional Efforts to Lose Weight: A Global Scale Analysis
  Morena Ustulin, So Young Park, Sang Ouk Chin, Suk Chon, Jeong-taek Woo, Sang Youl Rhee
  Diabetes & Metabolism Journal.2018; 42(4): 320.     CrossRef
• Phytol stimulates the browning of white adipocytes through the activation of AMP-activated protein kinase (AMPK) α in mice fed high-fat diet
  Fenglin Zhang, Wei Ai, Xiaoquan Hu, Yingying Meng, Cong Yuan, Han Su, Lina Wang, Xiaotong Zhu, Ping Gao, Gang Shu, Qingyan Jiang, Songbo Wang
  Food & Function.2018; 9(4): 2043.     CrossRef
• Nobiletin induces brown adipocyte-like phenotype and ameliorates stress in 3T3-L1 adipocytes
  Jameel Lone, Hilal Ahmad Parray, Jong Won Yun
  Biochimie.2018; 146: 97.     CrossRef
• Regular aerobic exercise correlates with reduced anxiety and incresed levels of irisin in brain and white adipose tissue
  Nazan Uysal, Oguz Yuksel, Servet Kizildag, Zeynep Yuce, Hikmet Gumus, Aslı Karakilic, Guven Guvendi, Basar Koc, Sevim Kandis, Mehmet Ates
  Neuroscience Letters.2018; 676: 92.     CrossRef
• The Root of Atractylodes macrocephala Koidzumi Prevents Obesity and Glucose Intolerance and Increases Energy Metabolism in Mice
  Mi Song, Soo-Kyoung Lim, Jing-Hua Wang, Hojun Kim
  International Journal of Molecular Sciences.2018; 19(1): 278.     CrossRef
• Differential actions of PPAR-α and PPAR-β/δ on beige adipocyte formation: A study in the subcutaneous white adipose tissue of obese male mice
  Tamiris Lima Rachid, Flavia Maria Silva-Veiga, Francielle Graus-Nunes, Isabele Bringhenti, Carlos Alberto Mandarim-de-Lacerda, Vanessa Souza-Mello, Nobuyuki Takahashi
  PLOS ONE.2018; 13(1): e0191365.     CrossRef
• Coordination Among Lipid Droplets, Peroxisomes, and Mitochondria Regulates Energy Expenditure Through the CIDE-ATGL-PPARα Pathway in Adipocytes
  Linkang Zhou, Miao Yu, Muhammad Arshad, Wenmin Wang, Ye Lu, Jingyi Gong, Yangnan Gu, Peng Li, Li Xu
  Diabetes.2018; 67(10): 1935.     CrossRef
• Lithocholic Acid Improves the Survival of Drosophila Melanogaster
  Stefanie Staats, Gerald Rimbach, Axel Kuenstner, Simon Graspeuntner, Jan Rupp, Hauke Busch, Christian Sina, Ignacio R. Ipharraguerre, Anika E. Wagner
  Molecular Nutrition & Food Research.2018;[Epub]     CrossRef
• Preconditioning lessens high fat induced metabolic syndrome along with markers of increased metabolic capacity in muscle and adipose tissue
  Songpei Li, Xiu Zhou, Eunjung Jo, Ali Mahzari, Sherouk Fouda, Dongli Li, Kun Zhang, Ji-Ming Ye
  Bioscience Reports.2018;[Epub]     CrossRef
• Alternative mRNA Splicing in the Pathogenesis of Obesity
  Chi-Ming Wong, Lu Xu, Mabel Yau
  International Journal of Molecular Sciences.2018; 19(2): 632.     CrossRef
• Krüppel-Like Factors
  Nina M. Pollak, Matthew Hoffman, Ira J. Goldberg, Konstantinos Drosatos
  JACC: Basic to Translational Science.2018; 3(1): 132.     CrossRef
• Dietary n-3 long-chain polyunsaturated fatty acids upregulate energy dissipating metabolic pathways conveying anti-obesogenic effects in mice
  Stefanie Worsch, Mathias Heikenwalder, Hans Hauner, Bernhard L. Bader
  Nutrition & Metabolism.2018;[Epub]     CrossRef
• Combination of Capsaicin and Hesperidin Reduces the Effectiveness of Each Compound To Decrease the Adipocyte Size and To Induce Browning Features in Adipose Tissue of Western Diet Fed Rats
  Andrea Mosqueda-Solís, Juana Sánchez, María P. Portillo, Andreu Palou, Catalina Picó
  Journal of Agricultural and Food Chemistry.2018; 66(37): 9679.     CrossRef
• Regulation of Adipose Tissue Metabolism by the Endocannabinoid System
  Robin van Eenige, Mario van der Stelt, Patrick C.N. Rensen, Sander Kooijman
  Trends in Endocrinology & Metabolism.2018; 29(5): 326.     CrossRef
• Cardiovascular and Metabolic Heterogeneity of Obesity
  Ian J. Neeland, Paul Poirier, Jean-Pierre Després
  Circulation.2018; 137(13): 1391.     CrossRef
• Zinc alpha2 glycoprotein promotes browning in adipocytes
  Xin-Hua Xiao, Xiao-Yan Qi, Ya-Di Wang, Li Ran, Jing Yang, Huan-Li Zhang, Can-Xin Xu, Ge-Bo Wen, Jiang-Hua Liu
  Biochemical and Biophysical Research Communications.2018; 496(2): 287.     CrossRef
• Impacts of High Sodium Intake on Obesity-related Gene Expression
  Minjee Lee, Miyoung Park, Juhee Kim, Soyoung Sung, Myoungsook Lee
  Journal of the East Asian Society of Dietary Life.2018; 28(5): 364.     CrossRef
• Programming mediated by fatty acids affects uncoupling protein 1 (UCP-1) in brown adipose tissue
  Perla P. Argentato, Helena de Cássia César, Débora Estadella, Luciana P. Pisani
  British Journal of Nutrition.2018; 120(6): 619.     CrossRef
• Reversal of Fatty Infiltration After Suprascapular Nerve Compression Release Is Dependent on UCP1 Expression in Mice
  Zili Wang, Brian T. Feeley, Hubert T. Kim, Xuhui Liu
  Clinical Orthopaedics & Related Research.2018; 476(8): 1665.     CrossRef
• Increase in relative skeletal muscle mass over time and its inverse association with metabolic syndrome development: a 7-year retrospective cohort study
  Gyuri Kim, Seung-Eun Lee, Ji Eun Jun, You-Bin Lee, Jiyeon Ahn, Ji Cheol Bae, Sang-Man Jin, Kyu Yeon Hur, Jae Hwan Jee, Moon-Kyu Lee, Jae Hyeon Kim
  Cardiovascular Diabetology.2018;[Epub]     CrossRef
• Myricetin-induced brown adipose tissue activation prevents obesity and insulin resistance in db/db mice
  Tao Hu, Xiaoxue Yuan, Gang Wei, Haoshu Luo, Hyuek Jong Lee, Wanzhu Jin
  European Journal of Nutrition.2018; 57(1): 391.     CrossRef
• Effects of growth hormone on uncoupling protein 1 in white adipose tissues in obese mice
  Misa Hayashi, Kumi Futawaka, Rie Koyama, Yue Fan, Midori Matsushita, Asuka Hirao, Yuki Fukuda, Ayako Nushida, Syoko Nezu, Tetsuya Tagami, Kenji Moriyama
  Growth Hormone & IGF Research.2017; 37: 31.     CrossRef
• Position paper of the European Society of Cardiology–working group of coronary pathophysiology and microcirculation: obesity and heart disease
  Lina Badimon, Raffaele Bugiardini, Edina Cenko, Judit Cubedo, Maria Dorobantu, Dirk J. Duncker, Ramón Estruch, Davor Milicic, Dimitris Tousoulis, Zorana Vasiljevic, Gemma Vilahur, Cor de Wit, Akos Koller
  European Heart Journal.2017; 38(25): 1951.     CrossRef
• Browning of Abdominal Aorta Perivascular Adipose Tissue Inhibits Adipose Tissue Inflammation
  Run-Mei Li, Sui-Qing Chen, Ning-Xi Zeng, Shu-Hui Zheng, Li Guan, Hai-Mei Liu, Le-Quan Zhou, Jin-Wen Xu
  Metabolic Syndrome and Related Disorders.2017; 15(9): 450.     CrossRef
• The role of adipose tissue in cancer-associated cachexia
  Janina A Vaitkus, Francesco S Celi
  Experimental Biology and Medicine.2017; 242(5): 473.     CrossRef
• Hormonal factors in the control of the browning of white adipose tissue
  Jiamiao Hu, Mark Christian
  Hormone Molecular Biology and Clinical Investigation.2017;[Epub]     CrossRef
• European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)
  Javier Egea, Isabel Fabregat, Yves M. Frapart, Pietro Ghezzi, Agnes Görlach, Thomas Kietzmann, Kateryna Kubaichuk, Ulla G. Knaus, Manuela G. Lopez, Gloria Olaso-Gonzalez, Andreas Petry, Rainer Schulz, Jose Vina, Paul Winyard, Kahina Abbas, Opeyemi S. Adem
  Redox Biology.2017; 13: 94.     CrossRef
• Resveratrol enhances brown adipocyte formation and function by activating AMP‐activated protein kinase (AMPK) α1 in mice fed high‐fat diet
  Songbo Wang, Xingwei Liang, Qiyuan Yang, Xing Fu, Meijun Zhu, B. D. Rodgers, Qingyan Jiang, Michael V. Dodson, Min Du
  Molecular Nutrition & Food Research.2017;[Epub]     CrossRef
• Adipoz doku ve enerji metabolizması üzerine etkileri
  Meltem Mermer, Nilüfer Acar TEK
  SDÜ Sağlık Bilimleri Dergisi.2017;[Epub]     CrossRef
• Physiological roles of macrophages
  Siamon Gordon, Luisa Martinez-Pomares
  Pflügers Archiv - European Journal of Physiology.2017; 469(3-4): 365.     CrossRef
• Brown Adipose Tissue Bioenergetics: A New Methodological Approach
  María Calderon‐Dominguez, Martín Alcalá, David Sebastián, Antonio Zorzano, Marta Viana, Dolors Serra, Laura Herrero
  Advanced Science.2017;[Epub]     CrossRef
• Honokiol exerts dual effects on browning and apoptosis of adipocytes
  Jameel Lone, Jong Won Yun
  Pharmacological Reports.2017; 69(6): 1357.     CrossRef
• The Mixed Herbal Extract, CAPA, Prevents Obesity and Glucose Intolerance in Obese Mice
  Miyoung Song
  Journal of Korean Medicine for Obesity Research.2017; 17(2): 119.     CrossRef
• Brown Adipose Tissue: an Update on Recent Findings
  Kara L. Marlatt, Eric Ravussin
  Current Obesity Reports.2017; 6(4): 389.     CrossRef
• Radix Stellariae extract prevents high-fat-diet-induced obesity in C57BL/6 mice by accelerating energy metabolism
  Yin Li, Xin Liu, Yu Fan, Baican Yang, Cheng Huang
  PeerJ.2017; 5: e3305.     CrossRef
• Adipocyte arrestin domain-containing 3 protein (Arrdc3) regulates uncoupling protein 1 (Ucp1) expression in white adipose independently of canonical changes in β-adrenergic receptor signaling
  Shannon H. Carroll, Ellen Zhang, Bing F. Wang, Katherine B. LeClair, Arifeen Rahman, David E. Cohen, Jorge Plutzky, Parth Patwari, Richard T. Lee, Makoto Kanzaki
  PLOS ONE.2017; 12(3): e0173823.     CrossRef
• Effect of Long-Term Green Tea Extract Supplementation on Peripheral Blood Leukocytes in CrossFit-Trained and Untrained Men
  Agata Żak, Ilona Pokora
  Central European Journal of Sport Sciences and Medicine.2017; 19: 67.     CrossRef
• Rapid modulation of lipid metabolism in C57BL/6J mice induced by eicosapentaenoic acid-enriched phospholipid from Cucumaria frondosa
  Lingyu Zhang, Dan Wang, Min Wen, Lei Du, Changhu Xue, Jingfeng Wang, Jie Xu, Yuming Wang
  Journal of Functional Foods.2017; 28: 28.     CrossRef
• Egr1 deficiency induces browning of inguinal subcutaneous white adipose tissue in mice
  Cécile Milet, Marianne Bléher, Kassandra Allbright, Mickael Orgeur, Fanny Coulpier, Delphine Duprez, Emmanuelle Havis
  Scientific Reports.2017;[Epub]     CrossRef
• Purinergic Receptors in Adipose Tissue As Potential Targets in Metabolic Disorders
  Marco Tozzi, Ivana Novak
  Frontiers in Pharmacology.2017;[Epub]     CrossRef
• Phyllodulcin, a Natural Sweetener, Regulates Obesity-Related Metabolic Changes and Fat Browning-Related Genes of Subcutaneous White Adipose Tissue in High-Fat Diet-Induced Obese Mice
  Eunju Kim, Soo-Min Lim, Min-Soo Kim, Sang-Ho Yoo, Yuri Kim
  Nutrients.2017; 9(10): 1049.     CrossRef
• Yogurt and Cardiometabolic Diseases: A Critical Review of Potential Mechanisms
  Melissa Anne Fernandez, Shirin Panahi, Noémie Daniel, Angelo Tremblay, André Marette
  Advances in Nutrition.2017; 8(6): 812.     CrossRef
• Système endocannabinoïde : effets sur le métabolisme glucidique, mais aussi lipidique
  A.-L. Sberna, P. Degrace, B. Vergès
  Médecine des Maladies Métaboliques.2016; 10(5): 407.     CrossRef
• The Fat Side of the Endocannabinoid System: Role of Endocannabinoids in the Adipocyte
  Isabelle Matias, Ilaria Belluomo, Daniela Cota
  Cannabis and Cannabinoid Research.2016; 1(1): 176.     CrossRef
• Liraglutide suppresses obesity and induces brown fat-like phenotype via Soluble Guanylyl Cyclase mediated pathwayin vivoandin vitro
  Endong Zhu, Yang Yang, Juanjuan Zhang, Yongmei Li, Chunjun Li, Liming Chen, Bei Sun
  Oncotarget.2016; 7(49): 81077.     CrossRef
• NS5ATP6 modulates intracellular triglyceride content through FGF21 and independently of SIRT1 and SREBP1
  Zhongshu Li, Shenghu Feng, Li Zhou, Shunai Liu, Jun Cheng
  Biochemical and Biophysical Research Communications.2016; 475(1): 133.     CrossRef
• Novel device for male infertility screening with single-ball lens microscope and smartphone
  Yoshitomo Kobori, Peter Pfanner, Gail S. Prins, Craig Niederberger
  Fertility and Sterility.2016; 106(3): 574.     CrossRef
• An Intestinal Microbiota–Farnesoid X Receptor Axis Modulates Metabolic Disease
  Frank J. Gonzalez, Changtao Jiang, Andrew D. Patterson
  Gastroenterology.2016; 151(5): 845.     CrossRef
• Feast and famine: Adipose tissue adaptations for healthy aging
  Daniele Lettieri Barbato, Katia Aquilano
  Ageing Research Reviews.2016; 28: 85.     CrossRef
• Hypothalamus and thermogenesis: Heating the BAT, browning the WAT
  Cristina Contreras, Rubén Nogueiras, Carlos Diéguez, Gema Medina-Gómez, Miguel López
  Molecular and Cellular Endocrinology.2016; 438: 107.     CrossRef
• Concomitant beige adipocyte differentiation upon induction of mesenchymal stem cells into brown adipocytes
  Yung-Li Wang, Shih-Pei Lin, Patrick C.H. Hsieh, Shih-Chieh Hung
  Biochemical and Biophysical Research Communications.2016; 478(2): 689.     CrossRef

Retinoid acid is a metabolite of vitamin A and functions as an important factor in cell survival, differentiation and death. Most previous studies on retinoid metabolism have focused on its association with cancer, hematologic and dermatologic disorders. Given the special concern over the recent increase in the prevalence of diabetes worldwide, the role of retinoid metabolism on glucose metabolism and insulin resistance in the human body is of marked importance. Therefore, in this issue, we review the literature on the association of retinoid metabolism with glucose tolerance, with regard to insulin secretion, pancreatic autoimmunity, insulin sensitivity and lipid metabolism. Further, we tried to assess the possibility of using retinoids as a novel therapeutic strategy for diabetes.

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• Dysregulated cysteine metabolism leads to worsened liver pathology in diabetes-tuberculosis comorbid condition
  Shweta Chaudhary, Falak Pahwa, Ranjan K. Nanda
  Journal of Biological Chemistry.2024; 300(2): 105634.     CrossRef
• Role of dietary antioxidants in diabetes: An overview
  Mohamed Shafras, Rasangi Sabaragamuwa, Mohamed Suwair
  Food Chemistry Advances.2024; 4: 100666.     CrossRef
• Characterization of the gut bacterial and viral microbiota in latent autoimmune diabetes in adults
  Casper S. Poulsen, Dan Hesse, Gabriel R. Fernandes, Tue H. Hansen, Timo Kern, Allan Linneberg, Lore Van Espen, Torben Jørgensen, Trine Nielsen, Amra C. Alibegovic, Jelle Matthijnssens, Oluf Pedersen, Henrik Vestergaard, Torben Hansen, Mette K. Andersen
  Scientific Reports.2024;[Epub]     CrossRef
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  Ahmed El-Sayed, Eman Ebissy, Ahmed Ateya
  Veterinary Research Communications.2024; 48(4): 2207.     CrossRef
• Association of plasma vitamin A level with type 2 diabetes mellitus: a community aging population-based cross-sectional study
  Pengfei Li, Jingjing Xu, Yujie Guo, Xiaojun Ma, Shaobo Zhou, Chi Zhang, Huiyan Yu, Ying Wang, Xixiang Wang, Linhong Yuan
  Food Science and Human Wellness.2024; 13(4): 2079.     CrossRef
• Retinoic acid in Parkinson's disease: Molecular insights, therapeutic advances, and future prospects
  Ashutosh Pareek, Runjhun Singhal, Aaushi Pareek, Terisha Ghazi, Devesh U. Kapoor, Yashumati Ratan, Arun Kumar Singh, Vivek Jain, Anil A. Chuturgoon
  Life Sciences.2024; 355: 123010.     CrossRef
• Retinoic acid signaling is critical for generation of pancreatic progenitors from human embryonic stem cells
  Niloufer P. Dumasia, Aparna P. Khanna, Prasad S. Pethe
  Growth Factors.2023; 41(1): 8.     CrossRef
• Immuno-metabolic control of the balance between Th17-polarized and regulatory T-cells during HIV infection
  Alexis Yero, Ralph-Sydney Mboumba Bouassa, Petronela Ancuta, Jerome Estaquier, Mohammad-Ali Jenabian
  Cytokine & Growth Factor Reviews.2023; 69: 1.     CrossRef
• The transcriptomic and epigenetic alterations in type 2 diabetes mellitus patients of Chinese Tibetan and Han populations
  Xian Wang, Jie Liu, Qiuhong Wang, Qiu Chen
  Frontiers in Endocrinology.2023;[Epub]     CrossRef
• Pericytes modulate islet immune cells and insulin secretion through Interleukin-33 production in mice
  Guzel Burganova, Anat Schonblum, Lina Sakhneny, Alona Epshtein, Tomer Wald, Mika Tzaig, Limor Landsman
  Frontiers in Endocrinology.2023;[Epub]     CrossRef
• Marine-Derived Compounds Applied in Cardiovascular Diseases: Submerged Medicinal Industry
  Wasim Akram, Mohd Rihan, Sakeel Ahmed, Swamita Arora, Sameer Ahmad, Rahul Vashishth
  Marine Drugs.2023; 21(3): 193.     CrossRef
• Metabolite Profiling of the Gut–Renal–Cerebral Axis Reveals a Particular Pattern in Early Diabetic Kidney Disease in T2DM Patients
  Lavinia Balint, Carmen Socaciu, Andreea Iulia Socaciu, Adrian Vlad, Florica Gadalean, Flaviu Bob, Oana Milas, Octavian Marius Cretu, Anca Suteanu-Simulescu, Mihaela Glavan, Silvia Ienciu, Maria Mogos, Dragos Catalin Jianu, Ligia Petrica
  International Journal of Molecular Sciences.2023; 24(7): 6212.     CrossRef
• Multimodal plasma metabolomics and lipidomics in elucidating metabolic perturbations in tuberculosis patients with concurrent type 2 diabetes
  Nguyen Thi Hai Yen, Nguyen Ky Anh, Rannissa Puspita Jayanti, Nguyen Ky Phat, Dinh Hoa Vu, Jong-Lyul Ghim, Sangzin Ahn, Jae-Gook Shin, Jee Youn Oh, Nguyen Phuoc Long, Dong Hyun Kim
  Biochimie.2023; 211: 153.     CrossRef
• Microbiota dysbiosis associated with type 2 diabetes-like effects caused by chronic exposure to a mixture of chlorinated persistent organic pollutants in zebrafish
  Hyojin Lee, Sojeong Yoon, Youngja Hwang Park, Jeong-Soo Lee, Dong Young Rhyu, Ki-Tae Kim
  Environmental Pollution.2023; 334: 122108.     CrossRef
• Hepatic retinaldehyde deficiency is involved in diabetes deterioration by enhancing PCK1- and G6PC-mediated gluconeogenesis
  Hanyu Yang, Mengxiang Su, Ming Liu, Yun Sheng, Liang Zhu, Lu Yang, Ruijing Mu, Jianjun Zou, Xiaodong Liu, Li Liu
  Acta Pharmaceutica Sinica B.2023; 13(9): 3728.     CrossRef
• The Association and Mediating Biomarkers of Serum Retinol in Influencing the Development of Type 2 Diabetes: A Prospective Cohort Study in Middle-Aged and Elderly Population
  Xiuyu Pang, Sen Yang, Xiaoyu Guo, Hongyin Li, Yingfeng Zhang, Chunbo Wei, Yu Wang, Changhao Sun, Ying Li
  Frontiers in Nutrition.2022;[Epub]     CrossRef
• The Effects of Acitretin on Insulin Resistance, Glucose Metabolism, and Lipid Levels in Patients with Psoriasis
  Satnam Singh Sachdev, Adawiyah Jamil, Preamala Gunabalasingam, Najeeb Ahmad Safdar
  Indian Journal of Dermatology.2022; 67(4): 349.     CrossRef
• Quantification of All-Trans Retinoic Acid by Liquid Chromatography–Tandem Mass Spectrometry and Association with Lipid Profile in Patients with Type 2 Diabetes
  Jakob Morgenstern, Thomas Fleming, Elisabeth Kliemank, Maik Brune, Peter Nawroth, Andreas Fischer
  Metabolites.2021; 11(1): 60.     CrossRef
• Vitamin A and Its Multi-Effects on Pancreas: Recent Advances and Prospects
  Yunting Zhou, Huiying Wang, Junming Zhou, Shanhu Qiu, Tingting Cai, Huiqin Li, Ziyang Shen, Yun Hu, Bo Ding, Menghui Luo, Rong Huang, Rengna Yan, Wei Xu, Cong He, Yumin Zhang, Fengfei Li, Zilin Sun, Jianhua Ma
  Frontiers in Endocrinology.2021;[Epub]     CrossRef
• Association between Vitamin A, E and Type 2 Diabetes Mellitus in Korea: Korean National Health and Nutrition Examination Survey 2016–2018
  Kyungpyo Kim, Junho Choi, Serng Bai Pak
  Korean Journal of Family Practice.2021; 11(2): 135.     CrossRef
• Serum Retinal and Retinoic Acid Predict the Development of Type 2 Diabetes Mellitus in Korean Subjects with Impaired Fasting Glucose from the KCPS-II Cohort
  Youngmin Han, Yeunsoo Yang, Minjoo Kim, Sun Ha Jee, Hye Jin Yoo, Jong Ho Lee
  Metabolites.2021; 11(8): 510.     CrossRef
• The Interactions of Insulin and Vitamin A Signaling Systems for the Regulation of Hepatic Glucose and Lipid Metabolism
  Guoxun Chen
  Cells.2021; 10(8): 2160.     CrossRef
• RETSAT Mutation Selected for Hypoxia Adaptation Inhibits Tumor Growth
  Xiulin Jiang, Yaomei He, Qiushuo Shen, Lincan Duan, Yixiao Yuan, Lin Tang, Yulin Shi, Baiyang Liu, Haoqing Zhai, Peng Shi, Cuiping Yang, Yongbin Chen
  Frontiers in Cell and Developmental Biology.2021;[Epub]     CrossRef
• Research Progress in Vitamin A and Autism Spectrum Disorder
  Zhonghui Liu, Jingyu Wang, Qu Xu, Qin Hong, Jiansheng Zhu, Xia Chi, Enzo Emanuele
  Behavioural Neurology.2021; 2021: 1.     CrossRef
• Reductive Effect of Acitretin on Blood Glucose Levels in Chinese Patients With Psoriasis
  Hua Qian, Yehong Kuang, Juan Su, Menglin Chen, Xiang Chen, Chengzhi Lv, Wangqing Chen, Wu Zhu
  Frontiers in Medicine.2021;[Epub]     CrossRef
• Preventive action of retinoids in metabolic syndrome/type 2 diabetic rats fed with citrus functional food enriched in β-cryptoxanthin
  Claudie Dhuique-Mayer, Laura Gence, Karine Portet, Didier Tousch, Patrick Poucheret
  Food & Function.2020; 11(10): 9263.     CrossRef
• CNV Association of Diverse Clinical Phenotypes from eMERGE reveals novel disease biology underlying cardiovascular disease
  Joseph T. Glessner, Jin Li, Akshatha Desai, Melody Palmer, Dokyoon Kim, Anastasia Marie Lucas, Xiao Chang, John J. Connolly, Berta Almoguera, John B. Harley, Gail P. Jarvik, Marylyn D. Ritchie, Patrick M.A. Sleiman, Dan M. Roden, David Crosslin, Hakon Hak
  International Journal of Cardiology.2020; 298: 107.     CrossRef
• Pancreatic stellate cell‐potentiated insulin secretion from Min6 cells is independent of interleukin 6‐mediated pathway
  Ratnakar R. Bynigeri, Sasikala Mitnala, Rupjyoti Talukdar, Surya S. Singh, Nageshwar R. Duvvuru
  Journal of Cellular Biochemistry.2020; 121(1): 840.     CrossRef
• Impaired CPT1A Gene Expression Response to Retinoic Acid Treatment in Human PBMC as Predictor of Metabolic Risk
  Margalida Cifre, Andreu Palou, Paula Oliver
  Nutrients.2020; 12(8): 2269.     CrossRef
• All-Trans Retinoic Acid Enhances both the Signaling for Priming and the Glycolysis for Activation of NLRP3 Inflammasome in Human Macrophage
  Ahmad Alatshan, Gergő E. Kovács, Azzam Aladdin, Zsolt Czimmerer, Krisztina Tar, Szilvia Benkő
  Cells.2020; 9(7): 1591.     CrossRef
• Genetic immune and inflammatory markers associated with diabetes in solid organ transplant recipients
  Lina Quteineh, Agnieszka Wójtowicz, Pierre-Yves Bochud, Severine Crettol, Frederik Vandenberghe, Jean-Pierre Venetz, Oriol Manuel, Dela Golshayan, Roger Lehmann, Nicolas J. Mueller, Isabelle Binet, Christian van Delden, Jürg Steiger, Paul Mohacsi, Jean-Fr
  American Journal of Transplantation.2019; 19(1): 238.     CrossRef
• Vitamin A and Wound Healing
  Roman Zinder, Rachel Cooley, Lucian G. Vlad, Joseph A. Molnar
  Nutrition in Clinical Practice.2019; 34(6): 839.     CrossRef
• In utero exposure to bisphenol-A disrupts key elements of retinoid system in male mice offspring
  Javier Esteban, Marina Serrano-Maciá, Ismael Sánchez-Pérez, Paloma Alonso-Magdalena, María de la Cruz Pellín, Marta García-Arévalo, Ángel Nadal, Jose Barril
  Food and Chemical Toxicology.2019; 126: 142.     CrossRef
• Risk variants disrupting enhancers of T H 1 and T REG cells in type 1 diabetes
  Peng Gao, Yasin Uzun, Bing He, Sarah E. Salamati, Julie K. M. Coffey, Eva Tsalikian, Kai Tan
  Proceedings of the National Academy of Sciences.2019; 116(15): 7581.     CrossRef
• Astaxanthin: A Potential Mitochondrial-Targeted Antioxidant Treatment in Diseases and with Aging
  Mónika Sztretye, Beatrix Dienes, Mónika Gönczi, Tamás Czirják, László Csernoch, László Dux, Péter Szentesi, Anikó Keller-Pintér
  Oxidative Medicine and Cellular Longevity.2019; 2019: 1.     CrossRef
• Design and rationale of the INSYTE study: A randomised, placebo controlled study to test the efficacy of a synbiotic on liver fat, disease biomarkers and intestinal microbiota in non-alcoholic fatty liver disease
  Eleonora Scorletti, Paul R. Afolabi, Elizabeth A. Miles, Debbie E. Smith, Amal Almehmadi, Albandri Alshathry, Helen E. Moyses, Geraldine F. Clough, Mark Wright, Janisha Patel, Laure Bindels, Nathalie M. Delzenne, Philip C. Calder, Christopher D. Byrne
  Contemporary Clinical Trials.2018; 71: 113.     CrossRef
• Protective effect of supplementation with biotin against high-fructose-induced metabolic syndrome in rats
  Asdrubal Aguilera-Mendez, María G. Hernández-Equihua, Alfonso C. Rueda-Rocha, Clotilde Guajardo-López, Renato Nieto-Aguilar, Deyanira Serrato-Ochoa, León F. Ruíz Herrera, José A. Guzmán-Nateras
  Nutrition Research.2018; 57: 86.     CrossRef
• Elevated Fibroblast growth factor 21 (FGF21) in obese, insulin resistant states is normalised by the synthetic retinoid Fenretinide in mice
  Nicola Morrice, George D. Mcilroy, Seshu R. Tammireddy, Jennifer Reekie, Kirsty D. Shearer, Mary K. Doherty, Mirela Delibegović, Phillip D. Whitfield, Nimesh Mody
  Scientific Reports.2017;[Epub]     CrossRef
• Vitamin supplements in type 2 diabetes mellitus management: A review
  Mabel Kar-Wai Yan, Hanan Khalil
  Diabetes & Metabolic Syndrome: Clinical Research & Reviews.2017; 11: S589.     CrossRef
• Isotretinoin als „second hit“ bei Schizophrenie?
  Michael Kaczmarczyk, Carolin Laqua, Julian Hellmann-Regen, Isabella Heuser, Francesca Regen, Eric Hahn
  NeuroTransmitter.2017; 28(1): 29.     CrossRef
• Role of vitamin A metabolism in IIH: Results from the idiopathic intracranial hypertension treatment trial
  J Libien, MJ Kupersmith, W Blaner, MP McDermott, S Gao, Y Liu, J Corbett, M Wall
  Journal of the Neurological Sciences.2017; 372: 78.     CrossRef
• Synthesis of a new insulin-mimetic anti-diabetic drug containing vitamin A and vanadium(IV) salt: Chemico-biological characterizations
  Abdel Majid A Adam, Ahmed M Naglah, Mohamed A Al-Omar, Moamen S Refat
  International Journal of Immunopathology and Pharmacology.2017; 30(3): 272.     CrossRef
• The LC–MS-based metabolomics of hydroxytyrosol administration in rats reveals amelioration of the metabolic syndrome
  Nikolaos Lemonakis, Hemant Poudyal, Maria Halabalaki, Lindsay Brown, Anthony Tsarbopoulos, Alexios-Leandros Skaltsounis, Evagelos Gikas
  Journal of Chromatography B.2017; 1041-1042: 45.     CrossRef
• High serum carotenoids are associated with lower risk for developing elevated serum alanine aminotransferase among Japanese subjects: the Mikkabi cohort study
  Minoru Sugiura, Mieko Nakamura, Kazunori Ogawa, Yoshinori Ikoma, Masamichi Yano
  British Journal of Nutrition.2016; 115(8): 1462.     CrossRef
• Retinoids have therapeutic action in type 2 diabetes
  Dilnasheen Meerza, Sarah Iqbal, Sufian Zaheer, Imrana Naseem
  Nutrition.2016; 32(7-8): 898.     CrossRef
• Altered retinol status and expression of retinol-related proteins in streptozotocin-induced type 1 diabetic model rats
  Kimitaka Takitani, Keisuke Inoue, Maki Koh, Hiroshi Miyazaki, Akiko Inoue, Kanta Kishi, Hiroshi Tamai
  Journal of Clinical Biochemistry and Nutrition.2015; 56(3): 195.     CrossRef
• Role of vitamin A in type 2 diabetes mellitus biology: Effects of intervention therapy in a deficient state
  Sarah Iqbal, Imrana Naseem
  Nutrition.2015; 31(7-8): 901.     CrossRef
• Prepartum vitamin A supplementation enhances goat doe health status and kid viability and performance
  Mabrouk A. Abd Eldaim, Khalid M. Gaafar, Ragab A. Darwish, Hamad D. Mahboub, Mohamed A. Helal
  Small Ruminant Research.2015; 129: 6.     CrossRef
• Beta Cell Function and the Nutritional State: Dietary Factors that Influence Insulin Secretion
  William T. Moore, Suzanne M. Bowser, Dane W. Fausnacht, Linda L. Staley, Kyung-Shin Suh, Dongmin Liu
  Current Diabetes Reports.2015;[Epub]     CrossRef
• High-serum carotenoids associated with lower risk for developing type 2 diabetes among Japanese subjects: Mikkabi cohort study
  Minoru Sugiura, Mieko Nakamura, Kazunori Ogawa, Yoshinori Ikoma, Masamichi Yano
  BMJ Open Diabetes Research & Care.2015; 3(1): e000147.     CrossRef
• Gestational diabetes: a risk of puerperal hypovitaminosis A?
  FERNANDA B.S. RESENDE, LARISSA Q. DE LIRA, EVELLYN C. GRILO, MAYARA S.R. LIMA, ROBERTO DIMENSTEIN
  Anais da Academia Brasileira de Ciências.2015; 87(1): 463.     CrossRef
• Plasma concentrations of retinol in obese children and adolescents: relationship to metabolic syndrome components
  Marcia Teske, Ana Paula B. Melges, Fabiola Isabel S. de Souza, Fernando Luiz A. Fonseca, Roseli Oselka S. Sarni
  Revista Paulista de Pediatria.2014; 32(1): 50.     CrossRef
• Proteomic analysis of livers from fat-fed mice deficient in either PKCδ or PKCε identifies Htatip2 as a regulator of lipid metabolism
  Bing M. Liao, Katy Raddatz, Ling Zhong, Benjamin L. Parker, Mark J. Raftery, Carsten Schmitz-Peiffer
  PROTEOMICS.2014; 14(21-22): 2578.     CrossRef
• Effect of all-trans-retinoic acid on the structure of thyroid gland and pituitary tyrotrophs in streptozotocin-diabetic male rats
  Ola A. Hussein, Amel M.M. Abdel-Hafez
  The Egyptian Journal of Histology.2013; 36(3): 691.     CrossRef
• Quantitative Proteomic and Functional Analysis of Liver Mitochondria from High Fat Diet (HFD) Diabetic Mice
  Yurong Guo, Manjula Darshi, Yuliang Ma, Guy A. Perkins, Zhouxin Shen, Kristofer J. Haushalter, Rintaro Saito, Ai Chen, Yun Sok Lee, Hemal H. Patel, Steven P. Briggs, Mark H. Ellisman, Jerrold M. Olefsky, Susan S. Taylor
  Molecular & Cellular Proteomics.2013; 12(12): 3744.     CrossRef
• Deriving at candidate genes of metabolic stress from pancreas of WNIN/GR-Ob mutant rats
  Himadri Singh, Nappanveettil Giridharan, Ramesh Bhonde, Vijayalakshmi Venkatesan
  Islets.2013; 5(4): 133.     CrossRef