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Janel L. Kopp 2 Articles
Hyperinsulinemia in Obesity, Inflammation, and Cancer
Anni M.Y. Zhang, Elizabeth A. Wellberg, Janel L. Kopp, James D. Johnson
Diabetes Metab J. 2021;45(4):622-622.   Published online July 30, 2021
DOI: https://doi.org/10.4093/dmj.2021.0131
Corrects: Diabetes Metab J 2021;45(3):285
  • 3,128 View
  • 85 Download
  • 7 Crossref
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    Frontiers in Endocrinology.2023;[Epub]     CrossRef
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    Alireza Bahrami, Karim Parastouei, Maryam Taghdir, Mojtaba Ghadyani
    European Journal of Cancer Prevention.2023;[Epub]     CrossRef
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    María Eugenia Lucena de Ustáriz, Katherine Jazmín Bonilla Adriano, Mónica Gabriela Moncayo Romero, Rosa Elisa Cruz Tenempaguay
    Anatomía Digital.2023; 6(4.3): 777.     CrossRef
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    Karlijn Burridge, Sandra M. Christensen, Angela Golden, Amy B. Ingersoll, Justin Tondt, Harold E. Bays
    Obesity Pillars.2022; 1: 100007.     CrossRef
  • Special Issue: Emerging Paradigms in Insulin Resistance
    J. Jason Collier, Susan J. Burke
    Biomedicines.2022; 10(7): 1471.     CrossRef
  • Obesity-Associated ECM Remodeling in Cancer Progression
    Junyan Li, Ren Xu
    Cancers.2022; 14(22): 5684.     CrossRef
Pathophysiology
Hyperinsulinemia in Obesity, Inflammation, and Cancer
Anni M.Y. Zhang, Elizabeth A. Wellberg, Janel L. Kopp, James D. Johnson
Diabetes Metab J. 2021;45(3):285-311.   Published online March 29, 2021
DOI: https://doi.org/10.4093/dmj.2020.0250
Correction in: Diabetes Metab J 2021;45(4):622
  • 22,855 View
  • 897 Download
  • 81 Web of Science
  • 88 Crossref
Graphical AbstractGraphical Abstract AbstractAbstract PDFPubReader   ePub   
The relative insufficiency of insulin secretion and/or insulin action causes diabetes. However, obesity and type 2 diabetes mellitus can be associated with an absolute increase in circulating insulin, a state known as hyperinsulinemia. Studies are beginning to elucidate the cause-effect relationships between hyperinsulinemia and numerous consequences of metabolic dysfunctions. Here, we review recent evidence demonstrating that hyperinsulinemia may play a role in inflammation, aging and development of cancers. In this review, we will focus on the consequences and mechanisms of excess insulin production and action, placing recent findings that have challenged dogma in the context of the existing body of literature. Where relevant, we elaborate on the role of specific signal transduction components in the actions of insulin and consequences of chronic hyperinsulinemia. By discussing the involvement of hyperinsulinemia in various metabolic and other chronic diseases, we may identify more effective therapeutics or lifestyle interventions for preventing or treating obesity, diabetes and cancer. We also seek to identify pertinent questions that are ripe for future investigation.

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  • High adherence to Western dietary pattern increases breast cancer risk (an EPIC-Spain study)
    Adela Castelló, Miguel Rodríguez-Barranco, Virginia Lope, Marcela Guevara, Sandra Colorado-Yohar, Ane Dorronsoro, José Ramón Quirós, Carlota Castro-Espin, Carmen Sayon-Orea, Carmen Santiuste, Pilar Amiano, Cristina Lasheras, María-José Sanchez, Marina Pol
    Maturitas.2024; 179: 107868.     CrossRef
  • Dietary Diabetes Risk Reduction Score (DDRRS) and Breast Cancer Risk: A Case-Control Study in Iran
    Milad Mohammadzadeh, Alireza Bahrami, Fatemeh Abdi, Fatemeh Ghafouri-Taleghani, Amin Paydareh, Saba Jalali, Zeinab Heidari, Bahram Rashidkhani
    Nutrition and Cancer.2024; 76(1): 106.     CrossRef
  • White adipocyte dysfunction and obesity-associated pathologies in humans
    Carolina E. Hagberg, Kirsty L. Spalding
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  • Cumulative exposure to impaired fasting glucose and gastrointestinal cancer risk: A nationwide cohort study
    Byeong Yun Ahn, Bokyung Kim, Sanghyun Park, Sang Gyun Kim, Kyungdo Han, Soo‐Jeong Cho
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  • Leptin receptor deficiency impedes metabolic surgery related-weight loss through inhibition of energy expenditure in db/db mice
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    Diabetology & Metabolic Syndrome.2024;[Epub]     CrossRef
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    Lorenzo Lippi, Alessandro de Sire, Arianna Folli, Alessio Turco, Stefano Moalli, Marco Marcasciano, Antonio Ammendolia, Marco Invernizzi
    Cancers.2024; 16(3): 521.     CrossRef
  • Exploring the Role of Hyperinsulinemia in Obesity-Associated Tumor Development
    Ericka Vélez-Bonet, Kristyn Gumpper-Fedus, Zobeida Cruz-Monserrate
    Cancer Research.2024; 84(3): 351.     CrossRef
  • Exploring Promising Therapies for Non-Alcoholic Fatty Liver Disease: A ClinicalTrials.gov Analysis
    Omar Hegazi, Samer Alalalmeh, Moyad Shahwan, Ammar Jairoun, Mansour Alourfi, Ghfran Bokhari, Abdullah Alkhattabi, Saeed Alsharif, Mohannad Aljehani, Abdulmalik Alsabban, Mohammad Almtrafi, Ysear Zakri, Abdullah AlMahmoud, Khalid Alghamdi, Ahmed Ashour, Na
    Diabetes, Metabolic Syndrome and Obesity.2024; Volume 17: 545.     CrossRef
  • Predictors of Cardiac Autonomic Dysfunction in Obesity-Related Hypertension
    Aqsa Mujaddadi, Saima Zaki, Majumi M Noohu, Irshad Husain Naqvi, Zubia Veqar
    High Blood Pressure & Cardiovascular Prevention.2024; 31(1): 77.     CrossRef
  • The obesity-autophagy-cancer axis: Mechanistic insights and therapeutic perspectives
    Amir Barzegar Behrooz, Marco Cordani, Alessandra Fiore, Massimo Donadelli, Joseph W. Gordon, Daniel J. Klionsky, Saeid Ghavami
    Seminars in Cancer Biology.2024; 99: 24.     CrossRef
  • Metformin’s role in lowering colorectal cancer risk among individuals with diabetes from the Southern Community Cohort Study
    Thomas Lawler, Zoe L. Walts, Lauren Giurini, Mark Steinwandel, Loren Lipworth, Harvey J. Murff, Wei Zheng, Shaneda Warren Andersen
    Cancer Epidemiology.2024; 90: 102566.     CrossRef
  • Sex differences in insulin regulation of skeletal muscle glycogen synthase and changes during weight loss and exercise in adults
    Alice S. Ryan, Guoyan Li, Shawna McMillin, Heidi K. Ortmeyer
    Obesity.2024; 32(4): 667.     CrossRef
  • Therapeutic Repurposing of Antidiabetic Drugs in Diabetes-associated Comorbidities
    Kalyani Pathak, Manash Pratim Pathak, Riya Saikia, Urvashee Gogoi, Ratna Jyoti Das, Pompy Patowary, Partha Pratim Kaishap, Smita Bordoloi, Jyotirmoy Das, Himangshu Sarma, Mohammad Zaki Ahmad, Aparoop Das
    Current Drug Therapy.2024; 19(2): 178.     CrossRef
  • The effect of metabolic syndrome on prognosis of diffuse large B-cell lymphoma
    Wenjing Xiong, Liru Li, Xue Hui, Yue Liu, Hongbin Li, Yue Zhang, Shu Zhao
    Clinical and Translational Oncology.2024;[Epub]     CrossRef
  • Impact of Obesity-Related Endoplasmic Reticulum Stress on Cancer and Associated Molecular Targets
    Joud AlBashtawi, Hend Al-Jaber, Sara Ahmed, Layla Al-Mansoori
    Biomedicines.2024; 12(4): 793.     CrossRef
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    Heléna Safadi, Ágnes Balogh, Judit Lám, Attila Nagy, Éva Belicza
    Diabetes Research and Clinical Practice.2024; 211: 111665.     CrossRef
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    Cristina Pagano, Erika di Zazzo, Giorgio Avilia, Beatrice Savarese, Giovanna Navarra, Maria Chiara Proto, Donatella Fiore, Monica Rienzo, Patrizia Gazzerro, Chiara Laezza, Maurizio Bifulco
    International Journal of Cancer.2023; 152(12): 2464.     CrossRef
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    Andrea Pretta, Pina Ziranu, Riccardo Giampieri, Clelia Donisi, Erika Cimbro, Dario Spanu, Eleonora Lai, Federica Pecci, Francesca Balconi, Alessio Lupi, Marta Pozzari, Mara Persano, Sara Murgia, Valeria Pusceddu, Marco Puzzoni, Rossana Berardi, Mario Scar
    Digestive and Liver Disease.2023; 55(5): 655.     CrossRef
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    Molecular Metabolism.2023; 68: 101667.     CrossRef
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    Journal of Translational Medicine.2023;[Epub]     CrossRef
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    International Journal of Molecular Sciences.2023; 24(5): 4974.     CrossRef
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    Therapeutic Advances in Chronic Disease.2023; 14: 204062232311615.     CrossRef
  • Both early and late maternal age at childbirth is associated with increasing odds of central obesity in offspring
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    American Journal of Human Biology.2023;[Epub]     CrossRef
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    Teresa L. Mastracci, Minoti Apte, Laufey T. Amundadottir, Alexandra Alvarsson, Steven Artandi, Melena D. Bellin, Ernesto Bernal-Mizrachi, Alejandro Caicedo, Martha Campbell-Thompson, Zobeida Cruz-Monserrate, Abdelfattah El Ouaamari, Kyle J. Gaulton, Andre
    Diabetes.2023; 72(4): 433.     CrossRef
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    Seminars in Cancer Biology.2023; 93: 36.     CrossRef
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    Reproductive Biology and Endocrinology.2023;[Epub]     CrossRef
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    Inflammation.2023; 46(5): 1966.     CrossRef
  • Cancer Risk and its Association With Diabetes Mellitus in Patients With Acromegaly: A Two Center-based Study
    Zhe-Hao Xiao, Cheng Wang, Yong Wang, Shang-Kun Yuan, Cheng Huang, Ren-Fang Chen, Yong Li
    Endocrine Practice.2023; 29(9): 699.     CrossRef
  • Obesity, diabetes, and cancer: epidemiology, pathophysiology, and potential interventions
    Leonardo de Andrade Mesquita, Laura Fink Wayerbacher, Gilberto Schwartsmann, Fernando Gerchman
    Archives of Endocrinology and Metabolism.2023;[Epub]     CrossRef
  • Insulin Stimulates IL-23 Expression in Human Adipocytes: A Possible Explanation for the Higher Prevalence of Psoriasis in Obesity
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  • Non-alcoholic fatty liver disease and diabetes mellitus as growing aetiologies of hepatocellular carcinoma
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  • Alteration of Metabolic Syndrome Is Associated with the Decreased Risk of Colorectal Cancer
    Eun Hyo Jin, Yoon Jin Choi, Joo Hyun Lim, Cheol Min Shin, Kyungdo Han, Dong Ho Lee
    Journal of Clinical Medicine.2023; 12(15): 4889.     CrossRef
  • Dietary interventions improve diabetic kidney disease, but not peripheral neuropathy, in a db/db mouse model of type 2 diabetes
    Stephanie A. Eid, Phillipe D. O'Brien, Katharina H. Kretzler, Dae‐Gyu Jang, Faye E. Mendelson, John M. Hayes, Andrew Carter, Hongyu Zhang, Subramaniam Pennathur, Frank C. Brosius, Emily J. Koubek, Eva L. Feldman
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    Vanda Marques, Fabiola Arella, Marta B. Afonso, André A. Santos, Cecília M.P. Rodrigues
    Clinical Science.2023; 137(15): 1095.     CrossRef
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    PLOS ONE.2023; 18(11): e0285335.     CrossRef
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    Nutrients.2023; 16(1): 26.     CrossRef
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    Junyuan Deng, Yujie Guo, Jiali Du, Jichun Gu, Lei Kong, Boan Tao, Ji Li, Deliang Fu
    Frontiers in Cell and Developmental Biology.2022;[Epub]     CrossRef
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    Cancer & Metabolism.2022;[Epub]     CrossRef
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    FEBS Open Bio.2022; 12(10): 1828.     CrossRef
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    Pedro Renato Chocair, Precil Diego Miranda de Menezes Neves, Victor Augusto Hamamoto Sato, Sara Mohrbacher, Érico Souza Oliveira, Leonardo Victor Barbosa Pereira, Alessandra Martins Bales, Fagner Pereira da Silva, John A. Duley, Américo Lourenço Cuvello-N
    Frontiers in Medicine.2022;[Epub]     CrossRef
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    Problems of Endocrinology.2022; 68(4): 59.     CrossRef
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    Thoracic Cancer.2022; 13(23): 3268.     CrossRef
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    World Journal of Clinical Cases.2022; 10(31): 11214.     CrossRef
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    Frontiers in Medicine.2022;[Epub]     CrossRef
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    Open Heart.2021; 8(2): e001680.     CrossRef
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    Diabetologia.2021; 64(10): 2138.     CrossRef
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Diabetes Metab J : Diabetes & Metabolism Journal