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Ihn-Ho Cho  (Cho IH) 1 Article
Diagnostic Accuracy of 64-Slice MDCT Coronary Angiography for the Assessment of Coronary Artery Disease in Korean Patients with Type 2 Diabetes
Jun Sung Moon, Ji Sung Yoon, Kyu Chang Won, Ihn-Ho Cho, Hyoung Woo Lee
Diabetes Metab J. 2013;37(1):54-62.   Published online February 15, 2013
DOI: https://doi.org/10.4093/dmj.2013.37.1.54
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  • 13 Crossref
AbstractAbstract PDFPubReader   
Background

A 64-slice multidetector computed tomography (MDCT) is well known to be a useful noninvasive form of angiography for the general population, but not for certain patients with diabetes. The aim of this study was to investigate the diagnostic accuracy and usefulness of 64-slice MDCT coronary angiography for detecting coronary artery disease in Korean patients with type 2 diabetes mellitus (T2DM).

Methods

A total of 240 patients were included, 74 of whom had type 2 diabetes (M:F=40:33; 41.8±9.5 years). We compared significant coronary stenosis (>50% luminal narrowing) in MDCT with invasive coronary angiography (ICA) by segment, artery, and patient. We also evaluated the influence of obesity and coronary calcium score on MDCT accuracy.

Results

Of the 4,064 coronary segments studied, 4,062 segments (T2DM=1,109) were assessed quantitatively by both MDCT and ICA, and 706 segments (T2DM=226) were detected as a significant lesion by ICA in all patients. Sensitivity, specificity, as well as positive and negative predictive values for the presence of significant stenosis in T2DM were: by segment, 89.4%, 96.4%, 85.8%, and 97.4%, respectively; by artery (n=222), 95.1%, 92.9%, 94.4%, and 93.8%, respectively; by patients (n=74), 98.4%, 100.0%, 98.4%, and 90.0%, respectively. Regardless of presence of diabetes, there was no significant difference in diagnostic accuracy. Obesity (≥25 kg/m2) and coronary calcium score did not also affect the diagnostic accuracy of MDCT.

Conclusion

The 64-slice MDCT coronary angiography was found to have similar diagnostic accuracy with ICA, regardless of diabetes. These results suggest MDCT may be helpful to reduce unnecessary invasive studies for patients with diabetes.

Citations

Citations to this article as recorded by  
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    Current Problems in Cardiology.2021; 46(4): 100766.     CrossRef
  • Assessment of high sensitivity C-reactive protein and coronary plaque characteristics by computed tomography in patients with and without diabetes mellitus
    Hai-Ting Zhou, De-Li Zhao, Guo-Kun Wang, Tian-Zuo Wang, Hong-Wei Liang, Jin-Ling Zhang
    BMC Cardiovascular Disorders.2020;[Epub]     CrossRef
  • Triglyceride Glucose-Waist Circumference Better Predicts Coronary Calcium Progression Compared with Other Indices of Insulin Resistance: A Longitudinal Observational Study
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    Journal of Clinical Medicine.2020; 10(1): 92.     CrossRef
  • The impact of non-alcoholic fatty liver disease and metabolic syndrome on the progression of coronary artery calcification
    Yun Kyung Cho, Yu Mi Kang, Jee Hee Yoo, Jiwoo Lee, Seung Eun Lee, Dong Hyun Yang, Joon-Won Kang, Joong-Yeol Park, Chang Hee Jung, Hong-Kyu Kim, Woo Je Lee
    Scientific Reports.2018;[Epub]     CrossRef
  • Effects of Low-density Lipoprotein Cholesterol on Coronary Artery Calcification Progression According to High-density Lipoprotein Cholesterol Levels
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    Archives of Medical Research.2017; 48(3): 284.     CrossRef
  • 2013 ACC/AHA Cholesterol Guideline Versus 2004 NCEP ATP III Guideline in the Prediction of Coronary Artery Calcification Progression in a Korean Population
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    Journal of the American Heart Association.2016;[Epub]     CrossRef
  • Imaging Quality Evaluation of Low Tube Voltage Coronary CT Angiography Using Low Concentration Contrast Medium
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    PLOS ONE.2015; 10(3): e0120539.     CrossRef
  • 2013 ACC/AHA versus 2004 NECP ATP III Guidelines in the Assignment of Statin Treatment in a Korean Population with Subclinical Coronary Atherosclerosis
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    PLOS ONE.2015; 10(9): e0137478.     CrossRef
  • Serum Total Bilirubin Levels Provide Additive Risk Information over the Framingham Risk Score for Identifying Asymptomatic Diabetic Patients at Higher Risk for Coronary Artery Stenosis
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    Diabetes & Metabolism Journal.2015; 39(5): 414.     CrossRef
  • Association between serum gamma-glutamyltransferase and the progression of coronary artery calcification
    Yun Kyung Cho, Yu Mi Kang, Jenie Yoonoo Hwang, Eun Hee Kim, Dong Hyun Yang, Joon-Won Kang, Joong-Yeol Park, Woo Je Lee, Hong-Kyu Kim, Chang Hee Jung
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  • Role of Bilirubin in Diabetic Vascular Complications: Can Bilirubin Predict More than Just Liver Disease?
    Jun Sung Moon
    Diabetes & Metabolism Journal.2015; 39(5): 384.     CrossRef
  • The Association of Rate of Weight Gain During Early Adulthood With the Prevalence of Subclinical Coronary Artery Disease in Recently Diagnosed Type 2 Diabetes: The MAXWEL-CAD Study
    Soo Lim, Sung Hee Choi, Kyoung Min Kim, Sang Il Choi, Eun Ju Chun, Min Joo Kim, Kyong Soo Park, Hak Chul Jang, Naveed Sattar
    Diabetes Care.2014; 37(9): 2491.     CrossRef
  • Retraction: Diagnostic Accuracy of 64-Slice MDCT Coronary Angiography for the Assessment of Coronary Artery Disease in Korean Patients with Type 2 Diabetes
    Jun Sung Moon, Ji Sung Yoon, Kyu Chang Won, Ihn-Ho Cho, Hyoung Woo Lee
    Diabetes & Metabolism Journal.2013; 37(3): 217.     CrossRef

Diabetes Metab J : Diabetes & Metabolism Journal