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Hyo Kyun Chung  (Chung HK) 1 Article
GDF15 Is a Novel Biomarker for Impaired Fasting Glucose
Jun Hwa Hong, Hyo Kyun Chung, Hye Yoon Park, Kyong-Hye Joung, Ju Hee Lee, Jin Gyu Jung, Koon Soon Kim, Hyun Jin Kim, Bon Jeong Ku, Minho Shong
Diabetes Metab J. 2014;38(6):472-479.   Published online December 15, 2014
DOI: https://doi.org/10.4093/dmj.2014.38.6.472
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AbstractAbstract PDFPubReader   
Background

Growth differentiation factor-15 (GDF15) is a protein that belongs to the transforming growth factor β superfamily. An elevated serum level of GDF15 was found to be associated with type 2 diabetes mellitus (T2DM). T2DM is an inflammatory disease that progresses from normal glucose tolerance (NGT) to impaired fasting glucose (IFG). Hence, we aimed to validate the relationship between GDF15 and IFG.

Methods

The participants were divided into the following three groups: NGT (n=137), IFG (n=29), and T2DM (n=75). The controls and T2DM outpatients visited the hospital for routine health check-ups. We used fasting blood glucose to detect IFG in nondiabetic patients. We checked the body mass index (BMI), C-reactive protein level, metabolic parameters, and fasting serum GDF15 level.

Results

Age, BMI, triglyceride, insulin, glucose, homeostatic model assessment-insulin resistance (HOMA-IR), and GDF15 levels were elevated in the IFG and T2DM groups compared to the NGT group. In the correlation analysis between metabolic parameters and GDF15, age and HOMA-IR had a significant positive correlation with GDF15 levels. GDF15 significantly discriminated between IFG and NGT, independent of age, BMI, and HOMA-IR. The serum levels of GDF15 were more elevated in men than in women. As a biomarker for IFG based on the receiver operating characteristic curve analysis, the cutoff value of GDF15 was 510 pg/mL in males and 400 pg/mL in females.

Conclusion

GDF15 had a positive correlation with IR independent of age and BMI, and the serum level of GDF15 was increased in the IFG and T2DM groups. GDF15 may be a novel biomarker for detecting IFG in nondiabetic patients.

Citations

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    Journal of the Endocrine Society.2024;[Epub]     CrossRef
  • Serum Growth Differentiation Factor 15 Levels Predict the Incidence of Frailty among Patients with Cardiometabolic Diseases
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    Gerontology.2024; 70(5): 517.     CrossRef
  • Growth differentiation factor 15 and malnutrition in older adults
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  • Evaluation of the relation between subclinical systolic dysfunction defined by four-dimensional speckle-tracking echocardiography and growth differentiation factor-15 levels in patients with acromegaly
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  • Nausea, vomiting and conflict in pregnancy
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    Evolution, Medicine, and Public Health.2024; 12(1): 75.     CrossRef
  • Correlations between growth differentiation factor 15 (GDF-15) serum levels and gene polymorphism with type 2 diabetes mellitus
    Qiumei Liu, Lidong Qin, Yujian Liang, Min Xu, Junling Zhang, Xiaoting Mo, Xu Tang, Yufu Lu, Xuexiu Wang, Jiejing Cao, Chuwu Huang, Jiahui Rong, Kaisheng Teng, Linhai Zhao, Songju Wu, Lei Luo, Qinyi Guan, TianTian Zhang, Wenjia Jin, Jian Qin, Jiansheng Cai
    Heliyon.2024; 10(12): e33044.     CrossRef
  • Growth differentiation factor 15 is not modified after weight loss induced by liraglutide in South Asians and Europids with type 2 diabetes mellitus
    Carlijn A. Hoekx, Maaike E. Straat, Maurice B. Bizino, Huub J. van Eyk, Hildebrandus J. Lamb, Johannes W. A. Smit, Ingrid M. Jazet, Saskia C. A. de Jager, Mariëtte R. Boon, Borja Martinez‐Tellez
    Experimental Physiology.2024; 109(8): 1292.     CrossRef
  • GDF-15 and mtDNA Deletions Are Useful Biomarkers of Mitochondrial Dysfunction in Insulin Resistance and PCOS
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    International Journal of Molecular Sciences.2024; 25(20): 10916.     CrossRef
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    Yaser Khajebishak, Amir Hossein Faghfouri, Ali Soleimani, Sadra Madani, Laleh Payahoo
    Hormone Molecular Biology and Clinical Investigation.2023; 44(2): 127.     CrossRef
  • Relationship between meteorin-like peptide (Metrnl) serum levels and inflammatory cytokines, oxidative stress biomarkers and body composition parameters in type 2 diabetes patients
    Yaser Khajebishak, Sadra Madani, Amir Hossein Faghfouri, Ali Soleimani, Sara Ilaei, Said Peyrovi, Laleh Payahoo
    Nutrition & Food Science.2023; 53(5): 861.     CrossRef
  • Effects of acute exercise and exercise training on plasma GDF15 concentrations and associations with appetite and cardiometabolic health in individuals with overweight or obesity – A secondary analysis of a randomized controlled trial
    Jonas Salling Quist, Anders Bue Klein, Kristine Færch, Kristine Beaulieu, Mads Rosenkilde, Anne Sofie Gram, Anders Sjödin, Signe Torekov, Bente Stallknecht, Christoffer Clemmensen, Martin Bæk Blond
    Appetite.2023; 182: 106423.     CrossRef
  • Significant increase of serum extracellular vesicle-packaged growth differentiation factor 15 in type 2 diabetes mellitus: a cross-sectional study
    Wen Zhao, Xinwei Li, Xinxin Li, Lu Peng, Yu Li, Yunhui Du, Jianxun He, Yanwen Qin, Huina Zhang
    European Journal of Medical Research.2023;[Epub]     CrossRef
  • Association between growth differentiation factor 15 levels and gestational diabetes mellitus: A combined analysis
    Yi-Cheng Lu, Song-Liang Liu, Yu-Shan Zhang, Fei Liang, Xiao-Yan Zhu, Yue Xiao, Jing Wang, Cong Ding, Sudipta Banerjee, Jie-Yun Yin, Qiu-Ping Ma
    Frontiers in Endocrinology.2023;[Epub]     CrossRef
  • Metformin triggers a kidney GDF15-dependent area postrema axis to regulate food intake and body weight
    Song-Yang Zhang, Kyla Bruce, Zahra Danaei, Rosa J.W. Li, Daniel R. Barros, Rachel Kuah, Yu-Mi Lim, Laura H. Mariani, David Z. Cherney, Jennifer F.M. Chiu, Heather N. Reich, Tony K.T. Lam
    Cell Metabolism.2023; 35(5): 875.     CrossRef
  • Growth differentiation factor 15 (GDF-15) in endocrinology
    Pedro Iglesias, Ramona A. Silvestre, Juan J. Díez
    Endocrine.2023; 81(3): 419.     CrossRef
  • Identification of biomarkers for glycaemic deterioration in type 2 diabetes
    Roderick C. Slieker, Louise A. Donnelly, Elina Akalestou, Livia Lopez-Noriega, Rana Melhem, Ayşim Güneş, Frederic Abou Azar, Alexander Efanov, Eleni Georgiadou, Hermine Muniangi-Muhitu, Mahsa Sheikh, Giuseppe N. Giordano, Mikael Åkerlund, Emma Ahlqvist, A
    Nature Communications.2023;[Epub]     CrossRef
  • Metabolic syndrome and Growth Differentiation Factor 15 in older adults
    Adrián Carballo-Casla, Esther García-Esquinas, Antonio Buño-Soto, Ellen A. Struijk, Esther López-García, Fernando Rodríguez-Artalejo, Rosario Ortolá
    GeroScience.2022; 44(2): 867.     CrossRef
  • Associations between GDF15 Levels and Pre-Diabetes in Non-Obese Subjects
    Hao-Chang Hung, Hung-Tsung Wu, Ching-Han Lin, Hsuan-Wen Chou, Horng-Yih Ou, Chih-Jen Chang
    Journal of Investigative Medicine.2022; 70(1): 79.     CrossRef
  • Growth Differentiation Factor-15 as a Biomarker of Obese Pre-diabetes and Type 2 Diabetes Mellitus in Indian Subjects: A Case-control Study
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    Current Diabetes Reviews.2022;[Epub]     CrossRef
  • Growth Differentiation Factor 15 Protects SH-SY5Y Cells From Rotenone-Induced Toxicity by Suppressing Mitochondrial Apoptosis
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    Frontiers in Aging Neuroscience.2022;[Epub]     CrossRef
  • GDF-15 as a Therapeutic Target of Diabetic Complications Increases the Risk of Gallstone Disease: Mendelian Randomization and Polygenic Risk Score Analysis
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    Frontiers in Genetics.2022;[Epub]     CrossRef
  • Sex-specific modulation of circulating growth differentiation factor-15 in patients with type 2 diabetes and/or obesity
    Mohamed Asrih, Flore Sinturel, Richard Dubos, Idris Guessous, Zoltan Pataky, Charna Dibner, François R Jornayvaz, Karim Gariani
    Endocrine Connections.2022;[Epub]     CrossRef
  • Raised circulating soluble growth differentiation factor 15 is negatively associated with testosterone level in hypogonadic men with type 2 diabetes
    Yufeng Mei, Yongnan Lyu, Juan Le, Di Li, Hang Liu, Zhiming Zhao, Yan Li
    Diabetes/Metabolism Research and Reviews.2022;[Epub]     CrossRef
  • NCAM1 and GDF15 are biomarkers of Charcot-Marie-Tooth disease in patients and mice
    Matthew J Jennings, Alexia Kagiava, Leen Vendredy, Emily L Spaulding, Marina Stavrou, Denisa Hathazi, Anika Grüneboom, Vicky De Winter, Burkhard Gess, Ulrike Schara, Oksana Pogoryelova, Hanns Lochmüller, Christoph H Borchers, Andreas Roos, Robert W Burges
    Brain.2022; 145(11): 3999.     CrossRef
  • Metformin and growth differentiation factor 15 (GDF15) in type 2 diabetes mellitus: A hidden treasure
    Hayder M. Al‐kuraishy, Ali I. Al‐Gareeb, Athanasios Alexiou, Marios Papadakis, Eman Hassan Nadwa, Sarah M. Albogami, Mohammed Alorabi, Hebatallah M. Saad, Gaber El‐Saber Batiha
    Journal of Diabetes.2022; 14(12): 806.     CrossRef
  • GDF15 is an exercise-induced hepatokine regulated by glucagon and insulin in humans
    Peter Plomgaard, Jakob S. Hansen, Logan K. Townsend, Anders Gudiksen, Niels H. Secher, Jens O. Clemmesen, Rene K. Støving, Jens P. Goetze, David C. Wright, Henriette Pilegaard
    Frontiers in Endocrinology.2022;[Epub]     CrossRef
  • A study of serum growth differentiation factor 15 in Indian women with and without gestational diabetes mellitus in the third trimester of pregnancy and its association with pro-inflammatory markers and glucose metabolism
    Sudipta Banerjee, Rana Bhattacharjee, Amitabh Sur, Pieu Adhikary, Subhankar Chowdhury
    Diabetology International.2021; 12(3): 254.     CrossRef
  • Growth Differentiation Factor 15 is a Cancer Cell-Induced Mitokine That Primes Thyroid Cancer Cells for Invasiveness
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    Thyroid.2021; 31(5): 772.     CrossRef
  • The GDF15-GFRAL Pathway in Health and Metabolic Disease: Friend or Foe?
    Samuel N. Breit, David A. Brown, Vicky Wang-Wei Tsai
    Annual Review of Physiology.2021; 83(1): 127.     CrossRef
  • Associations of GDF-15 and GDF-15/adiponectin ratio with odds of type 2 diabetes in the Chinese population
    Xiaoying Wu, Wenting Xuan, Lili You, Hong Lian, Feng Li, Xiaoyun Zhang, Qingyu Chen, Kan Sun, Chaogang Chen, Mingtong Xu, Yan Li, Li Yan, Xiuwei Zhang, Meng Ren
    Endocrine.2021; 72(2): 423.     CrossRef
  • Decreased serum growth differentiation factor 15 levels after lifestyle intervention in patients with newly diagnosed type 2 diabetes mellitus
    Xingxing He, Jiaorong Su, Xiaojing Ma, Jingyi Lu, Yufei Wang, Jun Yin, Yuqian Bao, Gang Hu, Jian Zhou
    Obesity Medicine.2021; 24: 100345.     CrossRef
  • The anti-diabetic effects of NAG-1/GDF15 on HFD/STZ-induced mice
    Pattawika Lertpatipanpong, Jaehak Lee, Ilju Kim, Thomas Eling, Seung Yeon Oh, Je Kyung Seong, Seung Joon Baek
    Scientific Reports.2021;[Epub]     CrossRef
  • The Regulation of Circulating Hepatokines by Fructose Ingestion in Humans
    Michael M Richter, Peter Plomgaard
    Journal of the Endocrine Society.2021;[Epub]     CrossRef
  • GDF15: emerging biology and therapeutic applications for obesity and cardiometabolic disease
    Dongdong Wang, Emily A. Day, Logan K. Townsend, Djordje Djordjevic, Sebastian Beck Jørgensen, Gregory R. Steinberg
    Nature Reviews Endocrinology.2021; 17(10): 592.     CrossRef
  • High Fat, High Sugar Diet and DJOS Bariatric Surgery Influence Plasma Levels of Fetuin-B, Growth Differentiation Factor-15, and Pentraxin 3 in Diet-Induced Obese Sprague–Dawley Rats
    Jakub Poloczek, Monika Tarnawska, Elżbieta Chełmecka, Piotr Łaszczyca, Janusz Gumprecht, Dominika Stygar
    Nutrients.2021; 13(10): 3632.     CrossRef
  • Serum growth differentiation factor 15 level is associated with muscle strength and lower extremity function in older patients with cardiometabolic disease
    Kazuhito Oba, Joji Ishikawa, Yoshiaki Tamura, Yasunori Fujita, Masafumi Ito, Ai Iizuka, Yoshinori Fujiwara, Remi Kodera, Ayumi Toba, Kenji Toyoshima, Yuko Chiba, Seijiro Mori, Masashi Tanaka, Hideki Ito, Kazumasa Harada, Atsushi Araki
    Geriatrics & Gerontology International.2020; 20(10): 980.     CrossRef
  • Growth differentiation factor 15 (GDF-15) is a potential biomarker of both diabetic kidney disease and future cardiovascular events in cohorts of individuals with type 2 diabetes: a proteomics approach
    Axel C. Carlsson, Christoph Nowak, Lars Lind, Carl Johan Östgren, Fredrik H. Nyström, Johan Sundström, Juan Jesus Carrero, Ulf Riserus, Erik Ingelsson, Tove Fall, Johan Ärnlöv
    Upsala Journal of Medical Sciences.2020; 125(1): 37.     CrossRef
  • Elevated Plasma Growth and Differentiation Factor 15 Is Associated With Slower Gait Speed and Lower Physical Performance in Healthy Community-Dwelling Adults
    Richard D Semba, Marta Gonzalez-Freire, Toshiko Tanaka, Angelique Biancotto, Pingbo Zhang, Michelle Shardell, Ruin Moaddel, Luigi Ferrucci, Anne Newman
    The Journals of Gerontology: Series A.2020; 75(1): 175.     CrossRef
  • Circulating Cardiac Biomarkers in Diabetes Mellitus: A New Dawn for Risk Stratification—A Narrative Review
    Alexander E. Berezin, Alexander A. Berezin
    Diabetes Therapy.2020; 11(6): 1271.     CrossRef
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    Mariya Markova, Liselot Koelman, Silke Hornemann, Olga Pivovarova, Stephanie Sucher, Juergen Machann, Natalia Rudovich, Ralph Thomann, Rosemarie Schneeweiss, Sascha Rohn, Andreas F.H. Pfeiffer, Krasimira Aleksandrova
    Clinical Nutrition.2020; 39(3): 862.     CrossRef
  • Effect of sleeve gastrectomy on plasma growth differentiation factor-15 (GDF15) in human
    Ponnie Robertlee Dolo, Libin Yao, Peng Peng Liu, Jason Widjaja, Song Meng, Chao Li, Xiaocheng Zhu
    The American Journal of Surgery.2020; 220(3): 725.     CrossRef
  • Prognostication of clinical outcomes in diabetes mellitus: Emerging role of cardiac biomarkers
    Alexander E. Berezin
    Diabetes & Metabolic Syndrome: Clinical Research & Reviews.2019; 13(2): 995.     CrossRef
  • Effect of bariatric surgery on plasma GDF15 in humans
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    Nutrition, Metabolism and Cardiovascular Diseases.2019; 29(4): 334.     CrossRef
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    Stéphanie Desmedt, Valérie Desmedt, Leen De Vos, Joris R. Delanghe, Reinhart Speeckaert, Marijn M. Speeckaert
    Critical Reviews in Clinical Laboratory Sciences.2019; 56(5): 333.     CrossRef
  • Hepatokines—a novel group of exercise factors
    Cora Weigert, Miriam Hoene, Peter Plomgaard
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    Disease Markers.2019; 2019: 1.     CrossRef
  • The mitochondrial unfolded protein response and mitohormesis: a perspective on metabolic diseases
    Hyon-Seung Yi, Joon Young Chang, Minho Shong
    Journal of Molecular Endocrinology.2018; 61(3): R91.     CrossRef
  • Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases
    Ana Luisa Cardoso, Adelaide Fernandes, Juan Antonio Aguilar-Pimentel, Martin Hrabě de Angelis, Joana Ribeiro Guedes, Maria Alexandra Brito, Saida Ortolano, Giovambattista Pani, Sophia Athanasopoulou, Efstathios S. Gonos, Markus Schosserer, Johannes Grilla
    Ageing Research Reviews.2018; 47: 214.     CrossRef
  • Serum Meteorin-like protein levels decreased in patients newly diagnosed with type 2 diabetes
    Ju Hee Lee, Yea Eun Kang, Ji Min Kim, Sorim Choung, Kyong Hye Joung, Hyun Jin Kim, Bon Jeong Ku
    Diabetes Research and Clinical Practice.2018; 135: 7.     CrossRef
  • Growth differentiation factor 15 predicts advanced fibrosis in biopsy‐proven non‐alcoholic fatty liver disease
    Bo Kyung Koo, Sung Hee Um, Dong Soo Seo, Sae Kyung Joo, Jeong Mo Bae, Jeong Hwan Park, Mee Soo Chang, Jung Ho Kim, Jieun Lee, Won‐Il Jeong, Won Kim
    Liver International.2018; 38(4): 695.     CrossRef
  • Serum Growth Differentiation Factor 15 in Parkinson Disease
    Xiaomei Yao, Dong Wang, Lei Zhang, Lingling Wang, Zhenxiang Zhao, Si Chen, Xiaotang Wang, Tao Yue, Yiming Liu
    Neurodegenerative Diseases.2017; 17(6): 251.     CrossRef
  • GDF15 deficiency exacerbates chronic alcohol- and carbon tetrachloride-induced liver injury
    Hyo Kyun Chung, Jung Tae Kim, Hyeon-Woo Kim, Minjoo Kwon, So Yeon Kim, Minho Shong, Koon Soon Kim, Hyon-Seung Yi
    Scientific Reports.2017;[Epub]     CrossRef
  • Growth differentiation factor 15 as a predictor of adverse renal outcomes in patients with immunoglobulin A nephropathy
    Ki R. Na, Yoo H. Kim, Hyo K. Chung, Min‐Kyung Yeo, Young R. Ham, Jin Y. Jeong, Koon S. Kim, Kang W. Lee, Dae E. Choi
    Internal Medicine Journal.2017; 47(12): 1393.     CrossRef
  • GDF15 contributes to radiation-induced senescence through the ROS-mediated p16 pathway in human endothelial cells
    Hyejin Park, Chun-Ho Kim, Jae-Hoon Jeong, Myungjin Park, Kwang Seok Kim
    Oncotarget.2016; 7(9): 9634.     CrossRef
  • GDF-15 and Hepcidin Levels in Nonanemic Patients with Impaired Glucose Tolerance
    Mehmet Muhittin Yalcin, Alev Eroglu Altinova, Mujde Akturk, Ozlem Gulbahar, Emre Arslan, Damla Ors Sendogan, Ilhan Yetkin, Fusun Balos Toruner
    Journal of Diabetes Research.2016; 2016: 1.     CrossRef
  • Cardiac‐Secreted Factors as Peripheral Metabolic Regulators and Potential Disease Biomarkers
    Colleen M. Dewey, Kathryn M. Spitler, Jessica M. Ponce, Duane D. Hall, Chad E. Grueter
    Journal of the American Heart Association.2016;[Epub]     CrossRef
  • Determinants of growth differentiation factor 15 in patients with stable and acute coronary artery disease. A prospective observational study
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    Cardiovascular Diabetology.2016;[Epub]     CrossRef
  • Effect of Atorvastatin on Growth Differentiation Factor-15 in Patients with Type 2 Diabetes Mellitus and Dyslipidemia
    Ji Min Kim, Min Kyung Back, Hyon-Seung Yi, Kyong Hye Joung, Hyun Jin Kim, Bon Jeong Ku
    Diabetes & Metabolism Journal.2016; 40(1): 70.     CrossRef
  • Association between Growth Differentiation Factor 15 (GDF15) and Cardiovascular Risk in Patients with Newly Diagnosed Type 2 Diabetes Mellitus
    Min Young Shin, Ji Min Kim, Yea Eun Kang, Min Kyeong Kim, Kyong Hye Joung, Ju Hee Lee, Koon Soon Kim, Hyun Jin Kim, Bon Jeong Ku, Minho Shong
    Journal of Korean Medical Science.2016; 31(9): 1413.     CrossRef
  • Comparison of Transcriptome Between Type 2 Diabetes Mellitus and Impaired Fasting Glucose
    Ying Cui, Wen Chen, Jinfeng Chi, Lei Wang
    Medical Science Monitor.2016; 22: 4699.     CrossRef
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