- GDF15 Is a Novel Biomarker for Impaired Fasting Glucose
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Jun Hwa Hong, Hyo Kyun Chung, Hye Yoon Park, Kyong-Hye Joung, Ju Hee Lee, Jin Gyu Jung, Koon Soon Kim, Hyun Jin Kim, Bon Jeong Ku, Minho Shong
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Diabetes Metab J. 2014;38(6):472-479. Published online December 15, 2014
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DOI: https://doi.org/10.4093/dmj.2014.38.6.472
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Abstract
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- Background
Growth differentiation factor-15 (GDF15) is a protein that belongs to the transforming growth factor β superfamily. An elevated serum level of GDF15 was found to be associated with type 2 diabetes mellitus (T2DM). T2DM is an inflammatory disease that progresses from normal glucose tolerance (NGT) to impaired fasting glucose (IFG). Hence, we aimed to validate the relationship between GDF15 and IFG. MethodsThe participants were divided into the following three groups: NGT (n=137), IFG (n=29), and T2DM (n=75). The controls and T2DM outpatients visited the hospital for routine health check-ups. We used fasting blood glucose to detect IFG in nondiabetic patients. We checked the body mass index (BMI), C-reactive protein level, metabolic parameters, and fasting serum GDF15 level. ResultsAge, BMI, triglyceride, insulin, glucose, homeostatic model assessment-insulin resistance (HOMA-IR), and GDF15 levels were elevated in the IFG and T2DM groups compared to the NGT group. In the correlation analysis between metabolic parameters and GDF15, age and HOMA-IR had a significant positive correlation with GDF15 levels. GDF15 significantly discriminated between IFG and NGT, independent of age, BMI, and HOMA-IR. The serum levels of GDF15 were more elevated in men than in women. As a biomarker for IFG based on the receiver operating characteristic curve analysis, the cutoff value of GDF15 was 510 pg/mL in males and 400 pg/mL in females. ConclusionGDF15 had a positive correlation with IR independent of age and BMI, and the serum level of GDF15 was increased in the IFG and T2DM groups. GDF15 may be a novel biomarker for detecting IFG in nondiabetic patients.
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Xingxing He, Jiaorong Su, Xiaojing Ma, Jingyi Lu, Yufei Wang, Jun Yin, Yuqian Bao, Gang Hu, Jian Zhou Obesity Medicine.2021; 24: 100345. CrossRef - The anti-diabetic effects of NAG-1/GDF15 on HFD/STZ-induced mice
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Kazuhito Oba, Joji Ishikawa, Yoshiaki Tamura, Yasunori Fujita, Masafumi Ito, Ai Iizuka, Yoshinori Fujiwara, Remi Kodera, Ayumi Toba, Kenji Toyoshima, Yuko Chiba, Seijiro Mori, Masashi Tanaka, Hideki Ito, Kazumasa Harada, Atsushi Araki Geriatrics & Gerontology International.2020; 20(10): 980. CrossRef - Growth differentiation factor 15 (GDF-15) is a potential biomarker of both diabetic kidney disease and future cardiovascular events in cohorts of individuals with type 2 diabetes: a proteomics approach
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Richard D Semba, Marta Gonzalez-Freire, Toshiko Tanaka, Angelique Biancotto, Pingbo Zhang, Michelle Shardell, Ruin Moaddel, Luigi Ferrucci, Anne Newman The Journals of Gerontology: Series A.2020; 75(1): 175. CrossRef - Circulating Cardiac Biomarkers in Diabetes Mellitus: A New Dawn for Risk Stratification—A Narrative Review
Alexander E. Berezin, Alexander A. Berezin Diabetes Therapy.2020; 11(6): 1271. CrossRef - Deterioration of Sleep Quality According to Glycemic Status
Myung Haeng Hur, Mi-Kyoung Lee, Kayeon Seong, Jun Hwa Hong Diabetes & Metabolism Journal.2020; 44(5): 679. CrossRef - Effects of plant and animal high protein diets on immune-inflammatory biomarkers: A 6-week intervention trial
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Ponnie Robertlee Dolo, Libin Yao, Peng Peng Liu, Jason Widjaja, Song Meng, Chao Li, Xiaocheng Zhu The American Journal of Surgery.2020; 220(3): 725. CrossRef - Prognostication of clinical outcomes in diabetes mellitus: Emerging role of cardiac biomarkers
Alexander E. Berezin Diabetes & Metabolic Syndrome: Clinical Research & Reviews.2019; 13(2): 995. CrossRef - Effect of bariatric surgery on plasma GDF15 in humans
Maximilian Kleinert, Kirstine N. Bojsen-Møller, Nils B. Jørgensen, Maria S. Svane, Christoffer Martinussen, Bente Kiens, Jørgen F.P. Wojtaszewski, Sten Madsbad, Erik A. Richter, Christoffer Clemmensen American Journal of Physiology-Endocrinology and Metabolism.2019; 316(4): E615. CrossRef - Regulation of Systemic Glucose Homeostasis by T Helper Type 2 Cytokines
Yea Eun Kang, Hyun Jin Kim, Minho Shong Diabetes & Metabolism Journal.2019; 43(5): 549. CrossRef - GDF15 reflects beta cell function in obese patients independently of the grade of impairment of glucose metabolism
M.H. Schernthaner-Reiter, B.K. Itariu, M. Krebs, M. Promintzer-Schifferl, T.M. Stulnig, A. Tura, C.H. Anderwald, M. Clodi, B. Ludvik, G. Pacini, A. Luger, G. Vila Nutrition, Metabolism and Cardiovascular Diseases.2019; 29(4): 334. CrossRef - Growth differentiation factor 15: A novel biomarker with high clinical potential
Stéphanie Desmedt, Valérie Desmedt, Leen De Vos, Joris R. Delanghe, Reinhart Speeckaert, Marijn M. Speeckaert Critical Reviews in Clinical Laboratory Sciences.2019; 56(5): 333. CrossRef - Hepatokines—a novel group of exercise factors
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Jianan Lu, Yue Zhang, Xingxuan Dong, Jiawen Lu, Chen Zhang, Jieyu Liu, Qingzhou Yu, Haoyue Teng, Qingkui Yao, Jieyun Yin, Liqiang Qin Disease Markers.2019; 2019: 1. CrossRef - The mitochondrial unfolded protein response and mitohormesis: a perspective on metabolic diseases
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Ju Hee Lee, Yea Eun Kang, Ji Min Kim, Sorim Choung, Kyong Hye Joung, Hyun Jin Kim, Bon Jeong Ku Diabetes Research and Clinical Practice.2018; 135: 7. CrossRef - Growth differentiation factor 15 predicts advanced fibrosis in biopsy‐proven non‐alcoholic fatty liver disease
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Xiaomei Yao, Dong Wang, Lei Zhang, Lingling Wang, Zhenxiang Zhao, Si Chen, Xiaotang Wang, Tao Yue, Yiming Liu Neurodegenerative Diseases.2017; 17(6): 251. CrossRef - GDF15 deficiency exacerbates chronic alcohol- and carbon tetrachloride-induced liver injury
Hyo Kyun Chung, Jung Tae Kim, Hyeon-Woo Kim, Minjoo Kwon, So Yeon Kim, Minho Shong, Koon Soon Kim, Hyon-Seung Yi Scientific Reports.2017;[Epub] CrossRef - Growth differentiation factor 15 as a predictor of adverse renal outcomes in patients with immunoglobulin A nephropathy
Ki R. Na, Yoo H. Kim, Hyo K. Chung, Min‐Kyung Yeo, Young R. Ham, Jin Y. Jeong, Koon S. Kim, Kang W. Lee, Dae E. Choi Internal Medicine Journal.2017; 47(12): 1393. CrossRef - GDF15 contributes to radiation-induced senescence through the ROS-mediated p16 pathway in human endothelial cells
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Colleen M. Dewey, Kathryn M. Spitler, Jessica M. Ponce, Duane D. Hall, Chad E. Grueter Journal of the American Heart Association.2016;[Epub] CrossRef - Determinants of growth differentiation factor 15 in patients with stable and acute coronary artery disease. A prospective observational study
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Ji Min Kim, Min Kyung Back, Hyon-Seung Yi, Kyong Hye Joung, Hyun Jin Kim, Bon Jeong Ku Diabetes & Metabolism Journal.2016; 40(1): 70. CrossRef - Association between Growth Differentiation Factor 15 (GDF15) and Cardiovascular Risk in Patients with Newly Diagnosed Type 2 Diabetes Mellitus
Min Young Shin, Ji Min Kim, Yea Eun Kang, Min Kyeong Kim, Kyong Hye Joung, Ju Hee Lee, Koon Soon Kim, Hyun Jin Kim, Bon Jeong Ku, Minho Shong Journal of Korean Medical Science.2016; 31(9): 1413. CrossRef - Comparison of Transcriptome Between Type 2 Diabetes Mellitus and Impaired Fasting Glucose
Ying Cui, Wen Chen, Jinfeng Chi, Lei Wang Medical Science Monitor.2016; 22: 4699. CrossRef - Letter: GDF15 Is a Novel Biomarker for Impaired Fasting Glucose (Diabetes Metab J2014;38:472-9)
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