Diabetes & Metabolism Journal

Chang Hee Jung (Jung CH)

21 Articles

Drug/Regimen
Efficacy and Safety of Metformin and Atorvastatin Combination Therapy vs. Monotherapy with Either Drug in Type 2 Diabetes Mellitus and Dyslipidemia Patients (ATOMIC): Double-Blinded Randomized Controlled Trial: Jie-Eun Lee, Seung Hee Yu, Sung Rae Kim, Kyu Jeung Ahn, Kee-Ho Song, In-Kyu Lee, Ho-Sang Shon, In Joo Kim, Soo Lim, Doo-Man Kim, Choon Hee Chung, Won-Young Lee, Soon Hee Lee, Dong Joon Kim, Sung-Rae Cho, Chang Hee Jung, Hyun Jeong Jeon, Seung-Hwan Lee, Keun-Young Park, Sang Youl Rhee, Sin Gon Kim, Seok O Park, Dae Jung Kim, Byung Joon Kim, Sang Ah Lee, Yong-Hyun Kim, Kyung-Soo Kim, Ji A Seo, Il Seong Nam-Goong, Chang Won Lee, Duk Kyu Kim, Sang Wook Kim, Chung Gu Cho, Jung Han Kim, Yeo-Joo Kim, Jae-Myung Yoo, Kyung Wan Min, Moon-Kyu Lee; Diabetes Metab J. 2024;48(4):730-739. Published online May 20, 2024; DOI: https://doi.org/10.4093/dmj.2023.0077

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Abstract PDF Supplementary Material PubReader ePub: Background
It is well known that a large number of patients with diabetes also have dyslipidemia, which significantly increases the risk of cardiovascular disease (CVD). This study aimed to evaluate the efficacy and safety of combination drugs consisting of metformin and atorvastatin, widely used as therapeutic agents for diabetes and dyslipidemia.
Methods
This randomized, double-blind, placebo-controlled, parallel-group and phase III multicenter study included adults with glycosylated hemoglobin (HbA1c) levels >7.0% and <10.0%, low-density lipoprotein cholesterol (LDL-C) >100 and <250 mg/dL. One hundred eighty-five eligible subjects were randomized to the combination group (metformin+atorvastatin), metformin group (metformin+atorvastatin placebo), and atorvastatin group (atorvastatin+metformin placebo). The primary efficacy endpoints were the percent changes in HbA1c and LDL-C levels from baseline at the end of the treatment.
Results
After 16 weeks of treatment compared to baseline, HbA1c showed a significant difference of 0.94% compared to the atorvastatin group in the combination group (0.35% vs. −0.58%, respectively; P<0.0001), whereas the proportion of patients with increased HbA1c was also 62% and 15%, respectively, showing a significant difference (P<0.001). The combination group also showed a significant decrease in LDL-C levels compared to the metformin group (−55.20% vs. −7.69%, P<0.001) without previously unknown adverse drug events.
Conclusion
The addition of atorvastatin to metformin improved HbA1c and LDL-C levels to a significant extent compared to metformin or atorvastatin alone in diabetes and dyslipidemia patients. This study also suggested metformin’s preventive effect on the glucose-elevating potential of atorvastatin in patients with type 2 diabetes mellitus and dyslipidemia, insufficiently controlled with exercise and diet. Metformin and atorvastatin combination might be an effective treatment in reducing the CVD risk in patients with both diabetes and dyslipidemia because of its lowering effect on LDL-C and glucose.

Pathophysiology
Immune-Checkpoint Inhibitors-Induced Type 1 Diabetes Mellitus: From Its Molecular Mechanisms to Clinical Practice: Yun Kyung Cho, Chang Hee Jung; Diabetes Metab J. 2023;47(6):757-766. Published online July 24, 2023; DOI: https://doi.org/10.4093/dmj.2023.0072

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With the increasing use of immune-checkpoint inhibitors (ICIs), such as anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and anti-programmed cell death-1 (PD-1), for the treatment of malignancies, cases of ICI-induced type 1 diabetes mellitus (ICI-T1DM) have been reported globally. This review focuses on the features and pathogenesis of this disease. T1DM is an immune-related adverse event that occurs following the administration of anti-PD-1 or anti-programmed death ligand-1 (PDL1) alone or in combination with anti-CTLA-4. More than half of the reported cases presented as abrupt-onset diabetic ketoacidosis. The primary mechanism of ICI-T1DM is T-cell stimulation, which results from the loss of interaction between PD-1 and PD-L1 in pancreatic islet. The similarities and differences between ICI-T1DM and classical T1DM may provide insights into this disease entity. ICI-T1DM is a rare but often life-threatening medical emergency that healthcare professionals and patients need to be aware of. Early detection of and screening for this disease is imperative. At present, the only known treatment for ICI-T1DM is insulin injection. Further research into the mechanisms and risk factors associated with ICI-T1DM development may contribute to a better understanding of this disease entity and the identification of possible preventive strategies.

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Diabetic ketoacidosis and hyperglycaemic hyperosmolar syndrome in patients with cancer: A multicentre study
Rabia K. Shahid, Qasem Haider, Sunil Yadav, Duc Le, Shahid Ahmed
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Research Advances of Immune Checkpoint Inhibitors Related Endocrine Adverse Events
晶晶王
Advances in Clinical Medicine.2024; 14(02): 2706. CrossRef
Immune checkpoint inhibitor‑associated diabetes mellitus in patients with HCC: Report of three cases and literature review
Gaocheng Wang, Jingjing Wang, Shuilin Dong, Zhanguo Zhang, Wanguang Zhang, Jianping Zhao
Experimental and Therapeutic Medicine.2024;[Epub] CrossRef
Type 1 diabetes: immune pathology and novel therapeutic approaches
Eleanor M. Ling, Joana R. N. Lemos, Khemraj Hirani, Matthias von Herrath
Diabetology International.2024; 15(4): 761. CrossRef
Pathophysiology, diagnosis, and management of immune checkpoint inhibitor-induced diabetes mellitus
Eleni-Rafaela Kani, Eleftheria Karaviti, Dimitra Karaviti, Eleni Gerontiti, Ioanna A. Paschou, Katerina Saltiki, Katerina Stefanaki, Theodora Psaltopoulou, Stavroula A. Paschou
Endocrine.2024;[Epub] CrossRef
Use pembrolizumab may cause acute and severe adverse reactions: a case report and review
Linna Ouyang, Huixing Liu, Zhixiang Tang, Rui Wu, Yujie Zhong, Haibin Chen
International Journal of Surgery Oncology.2024;[Epub] CrossRef
Pembrolizumab-Induced Insulin-Dependent Diabetes Mellitus in a Patient With Triple-Negative Breast Cancer: A Rare Immune-Related Adverse Event
Mirac Burak Tak, Zaid Munir, Ahmet Aydin
Cureus.2024;[Epub] CrossRef
Diabetes and the associated complications: The role of antioxidants in diabetes therapy and care
Lowell Dilworth, Dewayne Stennett, Aldeam Facey, Felix Omoruyi, Shada Mohansingh, Felix O. Omoruyi
Biomedicine & Pharmacotherapy.2024; 181: 117641. CrossRef
Immune checkpoint inhibitor‐related type 1 diabetes incidence, risk, and survival association
Fumika Kamitani, Yuichi Nishioka, Miyuki Koizumi, Hiroki Nakajima, Yukako Kurematsu, Sadanori Okada, Shinichiro Kubo, Tomoya Myojin, Tatsuya Noda, Tomoaki Imamura, Yutaka Takahashi
Journal of Diabetes Investigation.2024;[Epub] CrossRef

Comparing the Mortality Risk between Metabolic Dysfunction-Associated Fatty Liver Disease and Non-Alcoholic Fatty Liver Disease: Han Na Jung, Chang Hee Jung; Diabetes Metab J. 2023;47(2):198-200. Published online March 15, 2023; DOI: https://doi.org/10.4093/dmj.2023.0038

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Association of Myosteatosis with Nonalcoholic Fatty Liver Disease, Severity, and Liver Fibrosis Using Visual Muscular Quality Map in Computed Tomography (Diabetes Metab J 2023;47:104-17): Hwi Seung Kim, Hong-Kyu Kim, Chang Hee Jung; Diabetes Metab J. 2023;47(2):304-305. Published online March 15, 2023; DOI: https://doi.org/10.4093/dmj.2023.0058

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Association of NAFLD/NASH, and MAFLD/MASLD with chronic kidney disease: an updated narrative review
Amedeo Lonardo
Metabolism and Target Organ Damage.2024;[Epub] CrossRef

Metabolic Risk/Epidemiology
Association of Myosteatosis with Nonalcoholic Fatty Liver Disease, Severity, and Liver Fibrosis Using Visual Muscular Quality Map in Computed Tomography: Hwi Seung Kim, Jiwoo Lee, Eun Hee Kim, Min Jung Lee, In Young Bae, Woo Je Lee, Joong-Yeol Park, Hong-Kyu Kim, Chang Hee Jung; Diabetes Metab J. 2023;47(1):104-117. Published online January 26, 2023; DOI: https://doi.org/10.4093/dmj.2022.0081

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Background
The association of myosteatosis measured using visual muscular quality map in computed tomography (CT) with nonalcoholic fatty liver disease (NAFLD), its severity, and fibrosis was analyzed in a large population.
Methods
Subjects (n=13,452) with abdominal CT between 2012 and 2013 were measured total abdominal muscle area (TAMA) at L3 level. TAMA was segmented into intramuscular adipose tissue and skeletal muscle area (SMA), which was further classified into normal attenuation muscle area (NAMA) and low attenuation muscle area (LAMA). The following variables were adopted as indicators of myosteatosis: SMA/body mass index (BMI), NAMA/BMI, NAMA/TAMA, and LAMA/BMI. NAFLD and its severity were assessed by ultrasonography, and liver fibrosis was measured by calculating the NAFLD fibrosis score (NFS) and fibrosis-4 index (FIB-4) scores.
Results
According to multiple logistic regression analyses, as quartiles of SMA/BMI, NAMA/BMI, and NAMA/TAMA increased, the odds ratios (ORs) for NAFLD decreased in each sex (P for trend <0.001 for all). The ORs of moderate/severe NAFLD were significantly higher in the Q1 group than in the Q4 group for SMA/BMI, NAMA/BMI, and NAMA/TAMA in men. The ORs of intermediate/high liver fibrosis scores assessed by NFS and FIB-4 scores increased linearly with decreasing quartiles for SMA/BMI, NAMA/BMI, and NAMA/TAMA in each sex (P for trend <0.001 for all). Conversely, the risk for NAFLD and fibrosis were positively associated with LAMA/BMI quartiles in each sex (P for trend <0.001 for all).
Conclusion
A higher proportion of good quality muscle was associated with lower risks of NAFLD and fibrosis.

Citations

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Association between atherogenic dyslipidemia and muscle quality defined by myosteatosis
Hwi Seung Kim, Yun Kyung Cho, Myung Jin Kim, Eun Hee Kim, Min Jung Lee, Woo Je Lee, Hong-Kyu Kim, Chang Hee Jung
Frontiers in Endocrinology.2024;[Epub] CrossRef
Myosteatosis Predicts Bariatric Surgery Response: A Longitudinal Study in Patients With Morbid Obesity
Eugene Han, Mi Kyung Kim, Hye Won Lee, Seungwan Ryu, Hye Soon Kim, Byoung Kuk Jang, Youngsung Suh
The Journal of Clinical Endocrinology & Metabolism.2024;[Epub] CrossRef
Artificial intelligence-based evaluation of prognosis in cirrhosis
Yinping Zhai, Darong Hai, Li Zeng, Chenyan Lin, Xinru Tan, Zefei Mo, Qijia Tao, Wenhui Li, Xiaowei Xu, Qi Zhao, Jianwei Shuai, Jingye Pan
Journal of Translational Medicine.2024;[Epub] CrossRef
Association of Myosteatosis with Nonalcoholic Fatty Liver Disease, Severity, and Liver Fibrosis Using Visual Muscular Quality Map in Computed Tomography (Diabetes Metab J 2023;47:104-17)
Hwi Seung Kim, Hong-Kyu Kim, Chang Hee Jung
Diabetes & Metabolism Journal.2023; 47(2): 304. CrossRef
Association of Myosteatosis with Nonalcoholic Fatty Liver Disease, Severity, and Liver Fibrosis Using Visual Muscular Quality Map in Computed Tomography (Diabetes Metab J 2023;47:104-17)
Eun Roh
Diabetes & Metabolism Journal.2023; 47(2): 301. CrossRef
Sarcopenia, a condition shared by various diseases: can we alleviate or delay the progression?
Giovanni Tarantino, Gaia Sinatti, Vincenzo Citro, Silvano Santini, Clara Balsano
Internal and Emergency Medicine.2023; 18(7): 1887. CrossRef
Association of Visceral Fat Obesity, Sarcopenia, and Myosteatosis with Non-Alcoholic Fatty Liver Disease without Obesity
Hong-Kyu Kim, Sung-Jin Bae, Min Jung Lee, Eun Hee Kim, Hana Park, Hwi Seung Kim, Yun Kyung Cho, Chang Hee Jung, Woo Je Lee, Jaewon Choe
Clinical and Molecular Hepatology.2023; 29(4): 987. CrossRef
Current view of the surgical anatomy of the anterolateral abdominal wall muscles and their aponeuroses
A.V. Pavlov, A.S. Baranova, A.V. Fedoseyev, A.I. Vvedensky, G.S. Lazutina, N.V. Ovchinnikova, I.V. Bakharev
Operativnaya khirurgiya i klinicheskaya anatomiya (Pirogovskii nauchnyi zhurnal).2023; 7(3): 44. CrossRef
Muscle Fat Content Is Associated with Nonalcoholic Fatty Liver Disease and Liver Fibrosis in Chinese Adults
W. Guo, X. Zhao, D. Cheng, X. Liang, M. Miao, X. Li, J. Lu, N. Xu, Shuang Hu, Qun Zhang
The Journal of nutrition, health and aging.2023; 27(11): 960. CrossRef

Drug/Regimen
Clinical Efficacy of Sodium-Glucose Cotransporter 2 Inhibitor and Glucagon-Like Peptide-1 Receptor Agonist Combination Therapy in Type 2 Diabetes Mellitus: Real-World Study: Hwi Seung Kim, Taekwan Yoon, Chang Hee Jung, Joong-Yeol Park, Woo Je Lee; Diabetes Metab J. 2022;46(4):658-662. Published online November 8, 2021; DOI: https://doi.org/10.4093/dmj.2021.0232

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Sodium-glucose cotransporter 2 inhibitor (SGLT2i) and glucagon-like peptide-1 receptor agonist (GLP-1RA) are novel anti-diabetic drugs whose glucose-lowering effect and cardiovascular and renal benefits were evidenced in clinical trials. We investigated the real-world efficacy and safety of the combination of SGLT2i and GLP-1RA in patients with type 2 diabetes mellitus in Korea. The medical records of 104 patients who maintained the combination for at least 1 year were retrospectively reviewed. The change in glycosylated hemoglobin (HbA1c) after 6 months and 1 year of treatment was evaluated. The mean age was 51 years, and 41% were female. The mean baseline HbA1c, body mass index, and duration of diabetes were 9.0%, 28.8 kg/m², and 11.7 years, respectively. Compared with baseline, the HbA1c decreased by 1.5% (95% confidence interval [CI], 1.27 to 1.74; P<0.001) after 6 months and by 1.4% (95% CI, 1.19 to 1.70; P<0.001) after 1 year. Over 1 year, the bodyweight change was −2.8 kg (95% CI, −4.21 to −1.47; P<0.001). The combination of SGLT2i and GLP-1RA is effective and tolerable in type 2 diabetes mellitus patients in real-world practice.

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Effectiveness and safety of the combination of sodium–glucose transport protein 2 inhibitors and glucagon-like peptide-1 receptor agonists in patients with type 2 diabetes mellitus: a systematic review and meta-analysis of observational studies
Aftab Ahmad, Hani Sabbour
Cardiovascular Diabetology.2024;[Epub] CrossRef
Sodium–Glucose Cotransporter Inhibitors: Cellular Mechanisms Involved in the Lipid Metabolism and the Treatment of Chronic Kidney Disease Associated with Metabolic Syndrome
Fernando Cortés-Camacho, Oscar René Zambrano-Vásquez, Elena Aréchaga-Ocampo, Jorge Ismael Castañeda-Sánchez, José Guillermo Gonzaga-Sánchez, José Luis Sánchez-Gloria, Laura Gabriela Sánchez-Lozada, Horacio Osorio-Alonso
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SGLT2i and GLP1RA effects in patients followed in a hospital diabetology consultation
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Hormonal Gut–Brain Signaling for the Treatment of Obesity
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All‐cause mortality and cardiovascular outcomes with sodium‐glucose Co‐transporter 2 inhibitors, glucagon‐like peptide‐1 receptor agonists and with combination therapy in people with type 2 diabetes
David R. Riley, Hani Essa, Philip Austin, Frank Preston, Isatu Kargbo, Gema Hernández Ibarburu, Ramandeep Ghuman, Daniel J. Cuthbertson, Gregory Y. H. Lip, Uazman Alam
Diabetes, Obesity and Metabolism.2023; 25(10): 2897. CrossRef
The Efficacy and Safety of the Combination Therapy With GLP-1 Receptor Agonists and SGLT-2 Inhibitors in Type 2 Diabetes Mellitus: A Systematic Review and Meta-analysis
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Frontiers in Pharmacology.2022;[Epub] CrossRef
Clinical Efficacy of Sodium-Glucose Cotransporter 2 Inhibitor and Glucagon-Like Peptide-1 Receptor Agonist Combination Therapy in Type 2 Diabetes Mellitus: Real-World Study (Diabetes Metab J 2022;46: 658-62)
Hwi Seung Kim, Woo Je Lee
Diabetes & Metabolism Journal.2022; 46(4): 665. CrossRef
Clinical Efficacy of Sodium-Glucose Cotransporter 2 Inhibitor and Glucagon-Like Peptide-1 Receptor Agonist Combination Therapy in Type 2 Diabetes Mellitus: Real-World Study (Diabetes Metab J 2022;46: 658-62)
Tomoyuki Kawada
Diabetes & Metabolism Journal.2022; 46(4): 663. CrossRef
Durability of glucose-lowering effect of dulaglutide in patients with type 2 diabetes mellitus: A real-world data study
Hwi Seung Kim, Yun Kyung Cho, Myung Jin Kim, Chang Hee Jung, Joong-Yeol Park, Woo Je Lee
Frontiers in Endocrinology.2022;[Epub] CrossRef

Metabolic Risk/Epidemiology
Sex Differences of Visceral Fat Area and Visceral-to-Subcutaneous Fat Ratio for the Risk of Incident Type 2 Diabetes Mellitus: Eun Hee Kim, Hong-Kyu Kim, Min Jung Lee, Sung-Jin Bae, Jaewon Choe, Chang Hee Jung, Chul-Hee Kim, Joong-Yeol Park, Woo Je Lee; Diabetes Metab J. 2022;46(3):486-498. Published online November 18, 2021; DOI: https://doi.org/10.4093/dmj.2021.0095

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Background
This study aimed to determine the optimal cut-off values of visceral fat area (VFA) and visceral-to-subcutaneous fat ratio (VSR) for predicting incident type 2 diabetes mellitus (T2DM).
Methods
A total of 10,882 individuals (6,835 men; 4,047 women) free of T2DM at baseline aged between 30 and 79 years who underwent abdominal computed tomography scan between 2012 and 2013 as a part of routine health check-ups were included and followed. VFA, subcutaneous fat area, and VSR on L3 vertebral level were measured at baseline.
Results
During a median follow-up of 4.8 years, 730 (8.1% for men; 4.3% for women) incident cases of T2DM were identified. Receiver operating characteristic curve analysis showed that the optimal cut-off values of VFA and VSR for predicting incident T2DM were 130.03 cm² and 1.08 in men, respectively, and 85.7 cm² and 0.48 in women, respectively. Regardless of sex, higher VFA and VSR were significantly associated with a higher risk of incident T2DM. Compared with the lowest quartiles of VFA and VSR, the highest quartiles had adjusted odds ratios of 2.62 (95% confidence interval [CI], 1.73 to 3.97) and 1.55 (95% CI, 1.14 to 2.11) in men, respectively, and 32.49 (95% CI, 7.42 to 142.02) and 11.07 (95% CI, 3.89 to 31.50) in women, respectively.
Conclusion
Higher VFA and VSR at baseline were independent risk factors for the development of T2DM. Sex-specific reference values for visceral fat obesity (VFA ≥130 cm² or VSR ≥1.0 in men; VFA ≥85 cm² or VSR ≥0.5 in women) are proposed for the prediction of incident T2DM.

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Hyun-Jin Kim, Byungmi Kim, Seyoung Kim, Hyuktae Kwon, Jae Moon Yun, Belong Cho, Jin-Ho Park
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Association of Visceral Fat Obesity, Sarcopenia, and Myosteatosis with Non-Alcoholic Fatty Liver Disease without Obesity
Hong-Kyu Kim, Sung-Jin Bae, Min Jung Lee, Eun Hee Kim, Hana Park, Hwi Seung Kim, Yun Kyung Cho, Chang Hee Jung, Woo Je Lee, Jaewon Choe
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Drug/Regimen
Increasing Age Associated with Higher Dipeptidyl Peptidase-4 Inhibition Rate Is a Predictive Factor for Efficacy of Dipeptidyl Peptidase-4 Inhibitors: Sangmo Hong, Chang Hee Jung, Song Han, Cheol-Young Park; Diabetes Metab J. 2022;46(1):63-70. Published online April 19, 2021; DOI: https://doi.org/10.4093/dmj.2020.0253

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Graphical Abstract Abstract PDF Supplementary Material PubReader ePub: Background
It is not known which type 2 diabetes mellitus (T2DM) patients would most benefit from dipeptidyl peptidase-4 (DPP-4) inhibitor treatment. We aimed to investigate the predictors of response to DPP-4 inhibitors considering degree of DPP-4 inhibition.
Methods
This study is a post hoc analysis of a 24-week, randomized, double-blind, phase III trial that compared the efficacy and safety of a DPP-4 inhibitor (gemigliptin vs. sitagliptin) in patients with T2DM. Subjects were classified into tertiles of T1 <65.26%, T2=65.26%–76.35%, and T3 ≥76.35% by DPP-4 inhibition. We analyzed the change from baseline in glycosylated hemoglobin (HbA1c) according to DPP-4 inhibition with multiple linear regression adjusting for age, ethnicity, body mass index, baseline HbA1c, and DPP-4 activity at baseline.
Results
The mean age was greater in the high tertile group compared with the low tertile group (T1: 49.8±8.3 vs. T2: 53.1±10.5 vs. T3: 55.3±9.5, P<0.001) of DPP-4 inhibition. Although HbA1c at baseline was not different among tertiles of DPP-4 inhibition (P=0.398), HbA1c after 24-week treatment was lower in the higher tertile compares to the lower tertile (T1: 7.30%±0.88% vs. T2: 7.12%±0.78% vs. T3: 7.00%±0.78%, P=0.021). In multiple regression analysis, DPP-4 enzyme inhibition rate was not a significant determent for HbA1c reduction due to age. In subgroup analysis by tertile of DPP-4 inhibition, age was the only significant predictor and only in the highest tertile (R²=0.281, B=–0.014, P=0.024).
Conclusion
This study showed that HbA1c reduction by DPP-4 inhibitor was associated with increasing age, and this association was linked with higher DPP-4 inhibition.

Drug/Regimen
Dulaglutide as an Effective Replacement for Prandial Insulin in Kidney Transplant Recipients with Type 2 Diabetes Mellitus: A Retrospective Review: Hwi Seung Kim, Jiwoo Lee, Chang Hee Jung, Joong-Yeol Park, Woo Je Lee; Diabetes Metab J. 2021;45(6):948-953. Published online February 5, 2021; DOI: https://doi.org/10.4093/dmj.2020.0180

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Dulaglutide, a weekly injectable glucagon-like peptide-1 receptor agonist, has demonstrated effectiveness when combined with basal insulin. We examined whether the efficacy of dulaglutide is comparable to that of prandial insulin in kidney transplant (KT) recipients with type 2 diabetes mellitus (T2DM) undergoing multiple daily insulin injection (MDI) therapy. Thirty-seven patients, who switched from MDI therapy to basal insulin and dulaglutide, were retrospectively analyzed. Changes in glycosylated hemoglobin (HbA1c) and fasting plasma glucose (FPG) levels, body weight, and basal insulin dose were evaluated over 6 months. Dulaglutide was comparable to three injections of prandial insulin in terms of glycemic control (HbA1c 7.1% vs. 7.0%; 95% confidence interval [CI], –0.53 to 0.28; P=0.53). The basal insulin and dulaglutide combination resulted in a reduction in FPG levels by 9.7 mg/dL (95% CI, 2.09 to 41.54; P=0.03), in body weight by 4.9 kg (95% CI, 2.87 to 6.98; P<0.001), and in basal insulin dose by 9.52 IU (95% CI, 5.80 to 3.23; P<0.001). Once-weekly dulaglutide may be an effective alternative for thrice-daily prandial insulin in KT recipients with T2DM currently receiving MDI therapy.

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Diabetic Kidney Disease in Post-Kidney Transplant Patients
Ngoc-Yen T. Pham, Diego Cruz, Luis Madera-Marin, Raja Ravender, Pablo Garcia
Journal of Clinical Medicine.2024; 13(3): 793. CrossRef
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Pajaree Krisanapan, Supawadee Suppadungsuk, Kanokporn Sanpawithayakul, Charat Thongprayoon, Pattharawin Pattharanitima, Supawit Tangpanithandee, Michael A Mao, Jing Miao, Wisit Cheungpasitporn
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Safety and Efficacy of Sodium-Glucose Transport Protein 2 Inhibitors and Glucagon-like Peptide-1 Receptor Agonists in Diabetic Kidney Transplant Recipients: Synthesis of Evidence
Ioannis Bellos, Pagona Lagiou, Vassiliki Benetou, Smaragdi Marinaki
Journal of Clinical Medicine.2024; 13(20): 6181. CrossRef
GLP-1 Agonism for Kidney Transplant Recipients: A Narrative Review of Current Evidence and Future Directions Across the Research Spectrum
Victoria J. Riehl-Tonn, Kyle D. Medak, Christie Rampersad, Anne MacPhee, Tyrone G. Harrison
Canadian Journal of Kidney Health and Disease.2024;[Epub] CrossRef
Sweet and simple as syrup: A review and guidance for use of novel antihyperglycemic agents for post‐transplant diabetes mellitus and type 2 diabetes mellitus after kidney transplantation
S. Elise Lawrence, Mary Moss Chandran, Jeong M. Park, Helen Sweiss, Thomas Jensen, Palak Choksi, Barrett Crowther
Clinical Transplantation.2023;[Epub] CrossRef
Novel Drugs for the Management of Diabetes Kidney Transplant Patients: A Literature Review
Nancy Daniela Valencia-Morales, Beatriz Rodríguez-Cubillo, Rómulo Katsu Loayza-López, Maria Ángeles Moreno de la Higuera, Ana Isabel Sánchez-Fructuoso
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Luis Alberto Vigara, Florentino Villanego, Cristhian Orellana, Myriam Eady, María Gabriela Sánchez, Marta Alonso, María Belén García, José Manuel Amaro, Teresa García, Auxiliadora Mazuecos
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Tolerability and Effectiveness of Switching to Dulaglutide in Patients With Type 2 Diabetes Inadequately Controlled With Insulin Therapy
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Clinical Diabetes & Therapeutics
Asian Subpopulations May Exhibit Greater Cardiovascular Benefit from Long-Acting Glucagon-Like Peptide 1 Receptor Agonists: A Meta-Analysis of Cardiovascular Outcome Trials: Yu Mi Kang, Yun Kyung Cho, Jiwoo Lee, Seung Eun Lee, Woo Je Lee, Joong-Yeol Park, Ye-Jee Kim, Chang Hee Jung, Michael A. Nauck; Diabetes Metab J. 2019;43(4):410-421. Published online December 27, 2018; DOI: https://doi.org/10.4093/dmj.2018.0070

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Abstract PDF Supplementary Material PubReader

Background

Based on reported results of three large cardiovascular outcome trials (CVOTs) of glucagon-like peptide 1 receptor agonists (GLP-1 RAs), we aimed to investigate the overall effect of GLP-1 RAs on major adverse cardiovascular events (MACEs) and to identify subpopulations exhibiting the greatest cardiovascular (CV) benefit.

Methods

Three CVOTs reporting effects of long-acting GLP-1 RAs were included: LEADER (liraglutide), SUSTAIN-6 (semaglutide), and EXSCEL (exenatide once weekly). In all studies, the primary endpoint was three-point MACE, comprising CV death, non-fatal myocardial infarction, and non-fatal stroke. Overall effect estimates were calculated as hazard ratios and 95% confidence intervals (CIs) using the random-effects model; subgroup analyses reported in the original studies were similarly analyzed.

Results

Overall, statistically significant risk reductions in MACE and CV death were observed. Subgroup analysis indicated a significant racial difference with respect to CV benefit (P for interaction <0.001), and more substantial risk reductions were observed in subjects of African origin (relative risk [RR], 0.78; 95% CI, 0.60 to 0.99) and in Asians (RR, 0.35; 95% CI, 0.09 to 1.32). However, post hoc analysis (Bonferroni method) revealed that only Asians exhibited a significantly greater CV benefit from treatment, compared with white subjects (P<0.0001).

Conclusion

Long-acting GLP-1 RAs reduced risks of MACE and CV deaths in high-risk patients with type 2 diabetes mellitus. Our findings of a particularly effective reduction in CV events with GLP-1 RA in Asian populations merits further exploration and dedicated trials in specific populations.

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Jeonghee Han, Woo Je Lee, Kyu Yeon Hur, Jae Hyoung Cho, Byung Wan Lee, Cheol-Young Park
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Sex, racial, ethnic, and geographical disparities in major adverse cardiovascular outcome of glucagon-like peptide-1 receptor agonists among patients with and without diabetes mellitus: A meta-analysis of placebo-controlled randomized controlled trials
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A randomized, double‐blind trial assessing the efficacy and safety of two doses of dulaglutide in Japanese participants with type 2 diabetes (AWARD‐JPN)
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Vincenzo Sucato, Giuseppe Coppola, Girolamo Manno, Giuseppe Vadalà, Giuseppina Novo, Egle Corrado, Alfredo Ruggero Galassi
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Hodaka Yamada, Masashi Yoshida, Shunsuke Funazaki, Jun Morimoto, Shiori Tonezawa, Asuka Takahashi, Shuichi Nagashima, Kimura Masahiko, Otsuka Kiyoshi, Kazuo Hara
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Calvin Ke, K. M. Venkat Narayan, Juliana C. N. Chan, Prabhat Jha, Baiju R. Shah
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Timothy M. E. Davis, Anna Giczewska, Yuliya Lokhnygina, Robert J. Mentz, Naveed Sattar, Rury R. Holman
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Jian L. Yeo, Emer M. Brady, Gerry P. McCann, Gaurav S. Gulsin
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Clinical Diabetes & Therapeutics
Effectiveness and Safety of Adding Basal Insulin Glargine in Patients with Type 2 Diabetes Mellitus Exhibiting Inadequate Response to Metformin and DPP-4 Inhibitors with or without Sulfonylurea: Yu Mi Kang, Chang Hee Jung, Seung-Hwan Lee, Sang-Wook Kim, Kee-Ho Song, Sin Gon Kim, Jae Hyeon Kim, Young Min Cho, Tae Sun Park, Bon Jeong Ku, Gwanpyo Koh, Dol Mi Kim, Byung-Wan Lee, Joong-Yeol Park; Diabetes Metab J. 2019;43(4):432-446. Published online June 19, 2019; DOI: https://doi.org/10.4093/dmj.2018.0092

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Abstract PDF Supplementary Material PubReader

Background

We aimed to investigate the effectiveness and safety of adding basal insulin to initiating dipeptidyl peptidase-4 (DPP-4) inhibitor and metformin and/or sulfonylurea (SU) in achieving the target glycosylated hemoglobin (HbA1c) in patients with type 2 diabetes mellitus (T2DM).

Methods

This was a single-arm, multicenter, 24-week, open-label, phase 4 study in patients with inadequately controlled (HbA1c ≥7.5%) T2DM despite the use of DPP-4 inhibitor and metformin. A total of 108 patients received insulin glargine while continuing oral antidiabetic drugs (OADs). The primary efficacy endpoint was the percentage of subjects achieving HbA1c ≤7.0%. Other glycemic profiles were also evaluated, and the safety endpoints were adverse events (AEs) and hypoglycemia.

Results

The median HbA1c at baseline (8.9%; range, 7.5% to 11.1%) decreased to 7.6% (5.5% to 11.7%) at 24 weeks. Overall, 31.7% subjects (n=33) achieved the target HbA1c level of ≤7.0%. The mean differences in body weight and fasting plasma glucose were 1.2±3.4 kg and 56.0±49.8 mg/dL, respectively. Hypoglycemia was reported in 36 subjects (33.3%, 112 episodes), all of which were fully recovered. There was no serious AE attributed to insulin glargine. Body weight change was significantly different between SU users and nonusers (1.5±2.5 kg vs. −0.9±6.0 kg, P=0.011).

Conclusion

The combination add-on therapy of insulin glargine, on metformin and DPP-4 inhibitors with or without SU was safe and efficient in reducing HbA1c levels and thus, is a preferable option in managing T2DM patients exhibiting dysglycemia despite the use of OADs.

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Glycaemic control with add‐on thiazolidinedione or a sodium‐glucose co‐transporter‐2 inhibitor in patients with type 2 diabetes after the failure of an oral triple antidiabetic regimen: A 24‐week, randomized controlled trial
Jaehyun Bae, Ji Hye Huh, Minyoung Lee, Yong‐Ho Lee, Byung‐Wan Lee
Diabetes, Obesity and Metabolism.2021; 23(2): 609. CrossRef
Beneficial effect of anti-diabetic drugs for nonalcoholic fatty liver disease
Kyung-Soo Kim, Byung-Wan Lee
Clinical and Molecular Hepatology.2020; 26(4): 430. CrossRef

Clinical Diabetes & Therapeutics
Past and Current Status of Adult Type 2 Diabetes Mellitus Management in Korea: A National Health Insurance Service Database Analysis: Seung-Hyun Ko, Kyungdo Han, Yong-ho Lee, Junghyun Noh, Cheol-Young Park, Dae-Jung Kim, Chang Hee Jung, Ki-Up Lee, Kyung-Soo Ko; Diabetes Metab J. 2018;42(2):93-100. Published online April 19, 2018; DOI: https://doi.org/10.4093/dmj.2018.42.2.93

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Abstract PDF PubReader

Korea's National Healthcare Program, the National Health Insurance Service (NHIS), a government-affiliated agency under the Korean Ministry of Health and Welfare, covers the entire Korean population. The NHIS supervises all medical services in Korea and establishes a systematic National Health Information database (DB). A health information DB system including all of the claims, medications, death information, and health check-ups, both in the general population and in patients with various diseases, is not common worldwide. On June 9, 2014, the NHIS signed a memorandum of understanding with the Korean Diabetes Association (KDA) to provide limited open access to its DB. By October 31, 2017, seven papers had been published through this collaborative research project. These studies were conducted to investigate the past and current status of type 2 diabetes mellitus and its complications and management in Korea. This review is a brief summary of the collaborative projects between the KDA and the NHIS over the last 3 years. According to the analysis, the national health check-up DB or claim DB were used, and the age category or study period were differentially applied.

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Complications
Serum Total Bilirubin Levels Provide Additive Risk Information over the Framingham Risk Score for Identifying Asymptomatic Diabetic Patients at Higher Risk for Coronary Artery Stenosis: Jaechan Leem, Eun Hee Koh, Jung Eun Jang, Chang-Yun Woo, Jin Sun Oh, Min Jung Lee, Joon-Won Kang, Tae-Hwan Lim, Chang Hee Jung, Woo Je Lee, Joong-Yeol Park, Ki-Up Lee; Diabetes Metab J. 2015;39(5):414-423. Published online October 22, 2015; DOI: https://doi.org/10.4093/dmj.2015.39.5.414

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Background

The diagnosis of coronary artery disease (CAD) is often delayed in patients with type 2 diabetes. Serum total bilirubin levels are inversely associated with CAD. However, no studies have examined whether this can be used as a biochemical marker for identifying asymptomatic diabetic patients at higher risk for having obstructive CAD.

Methods

We performed a cross-sectional study of 460 consecutive asymptomatic patients with type 2 diabetes. All patients underwent coronary computed tomographic angiography, and their serum total bilirubin levels were measured. Obstructive CAD was defined as ≥50% diameter stenosis in at least one coronary artery.

Results

Serum total bilirubin tertiles showed an inverse association with the prevalence of obstructive CAD. In multivariate logistic regression analysis, the odds ratio for the highest versus the lowest tertile of total bilirubin was 0.227 (95% confidence interval [CI], 0.130 to 0.398), and an increment of 1 µmol/L in serum total bilirubin level was associated with a 14.6% decrease in obstructive CAD after adjustment for confounding variables. Receiver operating characteristic curve analysis showed that the area under the curve for the Framingham Risk Score (FRS) plus serum total bilirubin level was 0.712 (95% CI, 0.668 to 0.753), which is significantly greater than that of the FRS alone (P=0.0028).

Conclusion

Serum total bilirubin level is inversely associated with obstructive CAD and provides additive risk information over the FRS. Serum total bilirubin may be helpful for identifying asymptomatic patients with type 2 diabetes who are at higher risk for obstructive CAD.

Citations

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Response: Increased Risk of Hospitalization for Heart Failure with Newly Prescribed Dipeptidyl Peptidase-4 Inhibitors and Pioglitazone Using the Korean Health Insurance Claims Database (Diabetes Metab J 2015;39:247-52): Sunghwan Suh, Gi Hyeon Seo, Chang Hee Jung, Mee-Kyoung Kim, Sang-Man Jin, You-Cheol Hwang, Byung-Wan Lee, Jae Hyeon Kim; Diabetes Metab J. 2015;39(4):350-351. Published online August 17, 2015; DOI: https://doi.org/10.4093/dmj.2015.39.4.350

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Serum Ceruloplasmin Level as a Predictor for the Progression of Diabetic Nephropathy in Korean Men with Type 2 Diabetes Mellitus: Min Jung Lee, Chang Hee Jung, Yu Mi Kang, Jung Eun Jang, Jaechan Leem, Joong-Yeol Park, Woo Je Lee; Diabetes Metab J. 2015;39(3):230-239. Published online April 22, 2015; DOI: https://doi.org/10.4093/dmj.2015.39.3.230

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Background

Oxidative stress is known to be associated with progression of diabetic kidney disease. Ceruloplasmin acts as a pro-oxidant under conditions of severe oxidative stress. Thus, we conducted a longitudinal observational study to evaluate whether the serum ceruloplasmin level is a predictive biomarker for progression of diabetic nephropathy.

Methods

A total of 643 Korean men with type 2 diabetes mellitus were enrolled. Serum ceruloplasmin was measured using a nephelometric method. Progression of diabetic nephropathy was defined as transition in albuminuria class (i.e., normoalbuminuria to microalbuminuria, microalbuminuria to macroalbuminuria, or normoalbuminuria to macroalbuminuria) and/or a greater than 2-fold increase of serum creatinine at follow-up compared with the baseline value.

Results

During the follow-up period (median, 2.7 years; range, 0.3 to 4.4 years), 49 of 643 patients (7.6%) showed the progression of diabetic nephropathy and three patients (0.5%) developed end-stage renal disease. Baseline ceruloplasmin levels were higher in the progressors than in the nonprogressors (262.6±40.9 mg/L vs. 233.3±37.8 mg/L, P<0.001). Kaplan-Meier analysis showed a significantly higher incidence of nephropathy progression according to ceruloplasmin tertile (log-rank test, P<0.001). The hazard ratio (HR) for progression of diabetic nephropathy was significantly higher in the highest ceruloplasmin tertile category compared with the lowest ceruloplasmin tertile category, even after adjusting for confounding variables (HR, 3.32; 95% confidence interval, 1.28 to 8.61; P=0.003).

Conclusion

Baseline serum ceruloplasmin is an independent predictive factor for the progression of diabetic nephropathy in patients with type 2 diabetes mellitus.

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Biomarkers of diabetic nephropathy: A 2017 update
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Increased Risk of Hospitalization for Heart Failure with Newly Prescribed Dipeptidyl Peptidase-4 Inhibitors and Pioglitazone Using the Korean Health Insurance Claims Database: Sunghwan Suh, Gi Hyeon Seo, Chang Hee Jung, Mee-Kyoung Kim, Sang-Man Jin, You-Cheol Hwang, Byung-Wan Lee, Jae Hyeon Kim; Diabetes Metab J. 2015;39(3):247-252. Published online April 22, 2015; DOI: https://doi.org/10.4093/dmj.2015.39.3.247

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Background

We assessed the association of dipeptidyl peptidase 4 inhibitors (DPP4i) with hospitalization for heart failure (HF) using the Korean Health Insurance claims database.

Methods

We collected data on newly prescribed sitagliptin, vildagliptin, and pioglitazone between January 1, 2009 and December 31, 2012 (mean follow-up of 336.8 days) to 935,519 patients with diabetes (518,614 males and 416,905 females) aged 40 to 79 years (mean age of 59.4 years).

Results

During the study, 998 patients were hospitalized for primary HF (115.7 per 100,000 patient-years). The incidence rate of hospitalization for HF was 117.7 per 100,000 per patient-years among patients on pioglitazone, 105.7 for sitagliptin, and 135.8 for vildagliptin. The hospitalization rate for HF was greatest in the first 30 days after starting the medication, which corresponded to a significantly higher incidence at days 0 to 30 compared with days 31 to 360 for all three drugs. The hazard ratios were 1.85 (pioglitazone), 2.00 (sitagliptin), and 1.79 (vildagliptin). The incidence of hospitalization for HF did not differ between the drugs for any time period.

Conclusion

This study showed an increase in hospitalization for HF in the initial 30 days of the DPP4i and pioglitazone compared with the subsequent follow-up period. However, the differences between the drugs were not significant.

Citations

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Cardioprotective effects of dipeptidyl peptidase-4 inhibitors versus sulfonylureas in addition to metformin: A nationwide cohort study of patients with type 2 diabetes
Jui Wang, Hon-Yen Wu, Kuo-Liong Chien
Diabetes & Metabolism.2022; 48(3): 101299. CrossRef
Changing Fields-Diabetes Medications Invading the Cardiovascular Space
Lauren D. Breite, Mackenzie Steck, Brandon Tate Cutshall, Samarth P. Shah, Brandon E. Cave
Current Problems in Cardiology.2021; 46(3): 100736. CrossRef
Cardiovascular Safety and Benefits of Noninsulin Antihyperglycemic Drugs for the Treatment of Type 2 Diabetes Mellitus: Part 2
Srikanth Yandrapalli, Aaqib Malik, Adam Horblitt, Gayatri Pemmasani, Wilbert S. Aronow, William H. Frishman
Cardiology in Review.2020; 28(5): 219. CrossRef
Effects of antidiabetic drugs on left ventricular function/dysfunction: a systematic review and network meta-analysis
Da-Peng Zhang, Li Xu, Le-Feng Wang, Hong-Jiang Wang, Feng Jiang
Cardiovascular Diabetology.2020;[Epub] CrossRef
Dipeptidyl peptidase-4 inhibitor compared with sulfonylurea in combination with metformin: cardiovascular and renal outcomes in a propensity-matched cohort study
Kyoung Jin Kim, Jimi Choi, Juneyoung Lee, Jae Hyun Bae, Jee Hyun An, Hee Young Kim, Hye Jin Yoo, Ji A. Seo, Nan Hee Kim, Kyung Mook Choi, Sei Hyun Baik, Sin Gon Kim, Nam Hoon Kim
Cardiovascular Diabetology.2019;[Epub] CrossRef
Comparative Cardiovascular Risks of Dipeptidyl Peptidase-4 Inhibitors: Analyses of Real-world Data in Korea
Kyoung Hwa Ha, Bongseong Kim, Hae Sol Shin, Jinhee Lee, Hansol Choi, Hyeon Chang Kim, Dae Jung Kim
Korean Circulation Journal.2018; 48(5): 395. CrossRef
Worsening Heart Failure During the Use of DPP-4 Inhibitors
Milton Packer
JACC: Heart Failure.2018; 6(6): 445. CrossRef
Resistance exercise improves cardiac function and mitochondrial efficiency in diabetic rat hearts
Tae Hee Ko, Jubert C. Marquez, Hyoung Kyu Kim, Seung Hun Jeong, SungRyul Lee, Jae Boum Youm, In Sung Song, Dae Yun Seo, Hye Jin Kim, Du Nam Won, Kyoung Im Cho, Mun Gi Choi, Byoung Doo Rhee, Kyung Soo Ko, Nari Kim, Jong Chul Won, Jin Han
Pflügers Archiv - European Journal of Physiology.2018; 470(2): 263. CrossRef
Do DPP-4 Inhibitors Cause Heart Failure Events by Promoting Adrenergically Mediated Cardiotoxicity?
Milton Packer
Circulation Research.2018; 122(7): 928. CrossRef
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Hyouk-Jun Chin, Jin Hyun Nam, Eui-Kyung Lee, Ju-Young Shin
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Effects of dipeptidyl peptidase-4 inhibitor in insulin-resistant rats with myocardial infarction
Nattayaporn Apaijai, Tharnwimol Inthachai, Suree Lekawanvijit, Siriporn C Chattipakorn, Nipon Chattipakorn
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Christos V. Rizos, Anastazia Kei, Moses S. Elisaf
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Simón Quetzalcoatl Rodríguez-Lara, Ernesto German Cardona-Muñoz, Ernesto Javier Ramírez-Lizardo, Sylvia Elena Totsuka-Sutto, Araceli Castillo-Romero, Teresa Arcelia García-Cobián, Leonel García-Benavides, Kota V. Ramana
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Letter: Increased Risk of Hospitalization for Heart Failure with Newly Prescribed Dipeptidyl Peptidase-4 Inhibitors and Pioglitazone Using the Korean Health Insurance Claims Database (Diabetes Metab J2015;39:247-52)
Dae Ho Lee
Diabetes & Metabolism Journal.2015; 39(4): 348. CrossRef
Response: Increased Risk of Hospitalization for Heart Failure with Newly Prescribed Dipeptidyl Peptidase-4 Inhibitors and Pioglitazone Using the Korean Health Insurance Claims Database (Diabetes Metab J2015;39:247-52)
Sunghwan Suh, Gi Hyeon Seo, Chang Hee Jung, Mee-Kyoung Kim, Sang-Man Jin, You-Cheol Hwang, Byung-Wan Lee, Jae Hyeon Kim
Diabetes & Metabolism Journal.2015; 39(4): 350. CrossRef
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Dipeptidyl Peptidase-4 Inhibitor Alarms: Is Heart Failure Caused by a Class Effect?
Yong-ho Lee
Diabetes & Metabolism Journal.2015; 39(3): 204. CrossRef

Clinical Features and Causes of Endogenous Hyperinsulinemic Hypoglycemia in Korea: Chang-Yun Woo, Ji Yun Jeong, Jung Eun Jang, Jaechan Leem, Chang Hee Jung, Eun Hee Koh, Woo Je Lee, Min-Seon Kim, Joong-Yeol Park, Jung Bok Lee, Ki-Up Lee; Diabetes Metab J. 2015;39(2):126-131. Published online March 9, 2015; DOI: https://doi.org/10.4093/dmj.2015.39.2.126

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Background

Endogenous hyperinsulinemic hypoglycemia (EHH) is characterized by an inappropriately high plasma insulin level, despite a low plasma glucose level. Most of the EHH cases are caused by insulinoma, whereas nesidioblastosis and insulin autoimmune syndrome (IAS) are relatively rare.

Methods

To evaluate the relative frequencies of various causes of EHH in Korea, we retrospectively analyzed 84 patients who were diagnosed with EHH from 1998 to 2012 in a university hospital.

Results

Among the 84 EHH patients, 74 patients (88%), five (6%), and five (6%) were diagnosed with insulinoma, nesidioblastosis or IAS, respectively. The most common clinical manifestation of EHH was neuroglycopenic symptoms. Symptom duration before diagnosis was 14.5 months (range, 1 to 120 months) for insulinoma, 1.0 months (range, 6 days to 7 months) for nesidioblastosis, and 2.0 months (range, 1 to 12 months) for IAS. One patient, who was diagnosed with nesidioblastosis in 2006, underwent distal pancreatectomy but was later determined to be positive for insulin autoantibodies. Except for one patient who was diagnosed in 2007, the remaining three patients with nesidioblastosis demonstrated severe hyperinsulinemia (157 to 2,719 µIU/mL), which suggests that these patients might have had IAS, rather than nesidioblastosis.

Conclusion

The results of this study suggest that the prevalence of IAS may be higher in Korea than previously thought. Therefore, measurement of insulin autoantibody levels is warranted for EHH patients, especially in patients with very high plasma insulin levels.

Citations

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Case report: Insulinomatosis: description of four sporadic cases and review of the literature
Delmar Muniz Lourenço, Maria Lucia Corrêa-Giannella, Sheila Aparecida Coelho Siqueira, Marcia Nery, Flavio Galvão Ribeiro, Elizangela Pereira de Souza Quedas, Manoel de Souza Rocha, Ramon Marcelino do Nascimento, Maria Adelaide Albergaria Pereira
Frontiers in Endocrinology.2024;[Epub] CrossRef
Use of Translational Science, Continuous Glucose Monitoring in the Primary Care Setting for Management of Nesidioblastosis: A Case Report and Literature Review
Karuna Manandhar, Othman Farahneh, Ahmad Damlakhy, Ali Lattouf, Gerardo Munoz Monaco
Cureus.2024;[Epub] CrossRef
Insulin Autoimmune Syndrome: A Systematic Review
MingXu Lin, YuHua Chen, Jie Ning, Tatsuya Kin
International Journal of Endocrinology.2023; 2023: 1. CrossRef
Diffuse, Adult-Onset Nesidioblastosis/Non-Insulinoma Pancreatogenous Hypoglycemia Syndrome (NIPHS): Review of the Literature of a Rare Cause of Hyperinsulinemic Hypoglycemia
Martin Philipp Dieterle, Ayman Husari, Sophie Nicole Prozmann, Hendrik Wiethoff, Albrecht Stenzinger, Manuel Röhrich, Uwe Pfeiffer, Wolfgang Rüdiger Kießling, Helena Engel, Harald Sourij, Thorsten Steinberg, Pascal Tomakidi, Stefan Kopf, Julia Szendroedi
Biomedicines.2023; 11(6): 1732. CrossRef
An Uncommon Cause of Recurrent Presyncope, Dizziness, and Tachycardia: A Case Report of Diffuse, Adult-Onset Nesidioblastosis/Non-Insulinoma Pancreatogenous Hypoglycemia Syndrome (NIPHS)
Martin Philipp Dieterle, Ayman Husari, Sophie Nicole Prozmann, Hendrik Wiethoff, Albrecht Stenzinger, Manuel Röhrich, Uwe Pfeiffer, Wolfgang Rüdiger Kießling, Helena Engel, Harald Sourij, Thorsten Steinberg, Pascal Tomakidi, Stefan Kopf, Julia Szendroedi
Biomedicines.2023; 11(6): 1741. CrossRef
An Uncommon Case of Recurrent Hypoglycemic Episodes in a Healthy Non-diabetic Male: Insulin Autoimmune Syndrome
Kanwarpal K Dhaliwal, Gaurav Bector, Saurabh Arora, Amanpreet Singh, Sanjay Kalra
Cureus.2023;[Epub] CrossRef
The After-Dinner Dip
Caren G. Solomon, Gertrud L.G. Haverkamp, Richard G. Ijzerman, Jos Kooter, Yvonne H.M. Krul-Poel
New England Journal of Medicine.2022; 386(22): 2130. CrossRef
Hirata's disease (insulin autoimmune syndrome) following envenomation by a common krait
Subramanian Senthilkumaran, Stephen W. Miller, Harry F. Williams, Ponniah Thirumalaikolundusubramanian, Sakthivel Vaiyapuri, Ketan Patel
Toxicon.2022; 219: 106923. CrossRef
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Linli Sun, Weijin Fang, Dan Yi, Wei Sun, Chunjiang Wang
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Continuous glucose monitoring and Rituximab treatment in insulin autoimmune syndrome
Hiya Boro, Uttio Gupta, Charandeep Singh, Rakhi Malhotra, Rajesh Khadgawat
Diabetes & Metabolic Syndrome: Clinical Research & Reviews.2021; 15(6): 102294. CrossRef
Insulin Autoimmune Syndrome (Hirata Disease): A Comprehensive Review Fifty Years After Its First Description

Daniele Cappellani, Enrico Macchia, Alberto Falorni, Piero Marchetti
Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy.2020; Volume 13: 963. CrossRef
Nationwide survey of endogenous hyperinsulinemic hypoglycemia in Japan (2017–2018): Congenital hyperinsulinism, insulinoma, non‐insulinoma pancreatogenous hypoglycemia syndrome and insulin autoimmune syndrome (Hirata’s disease)
Yuki Yamada, Kana Kitayama, Maki Oyachi, Shinji Higuchi, Rie Kawakita, Yutaka Kanamori, Tohru Yorifuji
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Insulin Autoimmune Syndrome – A Case Series
Hiya Boro, Uttio Gupta, Charandeep Singh, Rakhi Malhotra, Rajesh Khadgawat
European Endocrinology.2020; 16(2): 168. CrossRef
Management of Insulin Autoimmune Hypoglycaemia: Single‐centre experience from Western India with systematic review of world literature
Muniraj Patel, Ravikumar Shah, Swati Ramteke‐Jadhav, Virendra Patil, Shivendra Kumar Patel, Anurag Lila, Nalini Shah, Tushar Bandgar
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Charline Bottinelli, Nathalie Cartiser, Fabien Bévalot, Laurent Fanton, Jérôme Guitton
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Yimin Shen, Xiaoxiao Song, Yuezhong Ren
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An observational analysis of insulinoma from a single institution
S Shao, Z Zeng, S Hu
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Anti-tuberculosis Treatment-Induced Insulin Autoimmune Syndrome
Jung Suk Han, Han Ju Moon, Jin Seo Kim, Hong Il Kim, Cheol Hyeon Kim, Min Joo Kim
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Spontaneous hypoglycemia: diagnostic evaluation and management
Leelavathy Kandaswamy, Rajeev Raghavan, Joseph M. Pappachan
Endocrine.2016; 53(1): 47. CrossRef
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Background and Data Configuration Process of a Nationwide Population-Based Study Using the Korean National Health Insurance System: Sun Ok Song, Chang Hee Jung, Young Duk Song, Cheol-Young Park, Hyuk-Sang Kwon, Bong Soo Cha, Joong-Yeol Park, Ki-Up Lee, Kyung Soo Ko, Byung-Wan Lee; Diabetes Metab J. 2014;38(5):395-403. Published online October 17, 2014; DOI: https://doi.org/10.4093/dmj.2014.38.5.395

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Background

The National Health Insurance Service (NHIS) recently signed an agreement to provide limited open access to the databases within the Korean Diabetes Association for the benefit of Korean subjects with diabetes. Here, we present the history, structure, contents, and way to use data procurement in the Korean National Health Insurance (NHI) system for the benefit of Korean researchers.

Methods

The NHIS in Korea is a single-payer program and is mandatory for all residents in Korea. The three main healthcare programs of the NHI, Medical Aid, and long-term care insurance (LTCI) provide 100% coverage for the Korean population. The NHIS in Korea has adopted a fee-for-service system to pay health providers. Researchers can obtain health information from the four databases of the insured that contain data on health insurance claims, health check-ups and LTCI.

Results

Metabolic disease as chronic disease is increasing with aging society. NHIS data is based on mandatory, serial population data, so, this might show the time course of disease and predict some disease progress, and also be used in primary and secondary prevention of disease after data mining.

Conclusion

The NHIS database represents the entire Korean population and can be used as a population-based database. The integrated information technology of the NHIS database makes it a world-leading population-based epidemiology and disease research platform.

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Hepatology.2024; 80(3): 633. CrossRef
Risk Factors of Pneumocystis jirovecii Pneumonia in Patients with Inflammatory Bowel Disease: A Nationwide Population-Based Study
Jiyoung Yoon, Seung Wook Hong, Kyung-Do Han, Seung-Woo Lee, Cheol Min Shin, Young Soo Park, Nayoung Kim, Dong Ho Lee, Joo Sung Kim, Hyuk Yoon
Gut and Liver.2024; 18(3): 489. CrossRef
Proteinuria and risk of ocular motor cranial nerve palsy: a nationwide population-based study
Juha Lee, Kyungdo Han, Juhwan Yoo, Kyung-Ah Park, Sei Yeul Oh
Scientific Reports.2024;[Epub] CrossRef
National trend in the prevalence and mortality of COPD in South Korea from 2008 to 2017
Sun-Hyung Kim, Jong Eun Park, Bumhee Yang, So Young Kim, Yeon Yong Kim, Jong Hyock Park
BMJ Open Respiratory Research.2024; 11(1): e002391. CrossRef
Proton Pump Inhibitor for Gastrointestinal Bleeding in Patients with Myocardial Infarction on Dual-Antiplatelet Therapy: A Nationwide Cohort Study
Minyoul Baik, Jimin Jeon, Jinkwon Kim, Joonsang Yoo
Journal of Epidemiology and Global Health.2024; 14(3): 1142. CrossRef
Cancer Incidence Among Residents Near Coal-Fired Power Plants Based on the Korean National Health Insurance System Data
Xue Han, Kyung-Hwa Choi, Hyungryul Lim, Jonghyuk Choi, Sanghyuk Bae, Mina Ha, Ho-Jang Kwon
Journal of Korean Medical Science.2024;[Epub] CrossRef
Risk of avascular necrosis in patients with inflammatory bowel disease: Insights from a nationwide cohort study and the impact of corticosteroid use
Jung Min Moon, Kyoung-Eun Kwon, Ju Won Lee, Kyung Rok Minn, Kyuwon Kim, Jeongkuk Seo, Seung Yong Shin, Sun-Young Jung, Chang Hwan Choi
Digestive and Liver Disease.2024;[Epub] CrossRef
Liver Cancer Risk Across Metabolic Dysfunction-Associated Steatotic Liver Disease and/or Alcohol: A Nationwide Study
Byungyoon Yun, Heejoo Park, Sang Hoon Ahn, Juyeon Oh, Beom Kyung Kim, Jin-Ha Yoon
American Journal of Gastroenterology.2024;[Epub] CrossRef
Fenofibrate’s impact on cardiovascular risk in patients with diabetes: a nationwide propensity-score matched cohort study
Sangmo Hong, Kyung-Soo Kim, Kyungdo Han, Cheol-Young Park
Cardiovascular Diabetology.2024;[Epub] CrossRef
Nationwide analysis of EVAR explantation outcomes in Korea: A comprehensive dataset study
Hyo Kee Kim, Pyoung Jae Park, Jee Hyun Park, Young Ju Oh, Cheol Woong Jung, Heungman Jun
Vascular.2024;[Epub] CrossRef
Chronic periodontal disease is related with newly developing hypertension: a nationwide cohort study
Jung-Hyun Park, Min Kyoung Kang, Gwang Hyun Leem, Jin-Woo Kim, Tae-Jin Song
Clinical Hypertension.2024;[Epub] CrossRef
Elevated Risk of Stroke in Young Adults After Traumatic Brain Injury: A Nationwide Study of 1 Million Individuals
Yoonjeong Choi, Jooeun Jeon, Eun Jin Ha, Chi Kyung Kim, Han Gil Seo, Byung‐Mo Oh, Ja‐Ho Leigh
Journal of the American Heart Association.2024;[Epub] CrossRef
Improved Proteinuria May Attenuate the Risk of Atrial Fibrillation: A Nationwide Population-Based Cohort Study
Yoonkyung Chang, Min Kyoung Kang, Tae-Jin Song
Journal of Clinical Medicine.2024; 13(16): 4648. CrossRef
Estimated economic costs of dental implants among older South Korean adults, 2015–2018
Hyeonjeong Go, Jeonghoon Ahn, Song Vogue Ahn, Hosung Shin, Atsuo Amano, Youn‐Hee Choi
Clinical Oral Implants Research.2024;[Epub] CrossRef
Risk of depression in amyotrophic lateral sclerosis: A nationwide cohort study in South Korea
Soonwook Kwon, Bongseong Kim, Kyung-Do Han, Wonyoung Jung, Eun Bin Cho, Dong Wook Shin, Ju-Hong Min
Journal of Psychiatric Research.2024; 178: 414. CrossRef
Association Between Influenza Vaccination and Acute Kidney Injury Among the Elderly: A Self‐Controlled Case Series
Haerin Cho, Eunsun Lim, Hee‐Jin Kim, Na‐Young Jeong, Nam‐Kyong Choi
Pharmacoepidemiology and Drug Safety.2024;[Epub] CrossRef
The association of fatty liver index and metabolic syndrome with cardiovascular outcomes, liver-related mortality, and all-cause mortality: a nationwide cohort study
So Hee Park, Jiyun Park, Hasung Kim, Jungkuk Lee, So Yoon Kwon, You-Bin Lee, Gyuri Kim, Sang-Man Jin, Kyu Yeon Hur, Jae Hyeon Kim
Internal and Emergency Medicine.2024;[Epub] CrossRef
Association of varicose veins with incidence risk of atrial fibrillation: a population-based cohort study
Soyoun Choi, Gwang-Hyun Leem, Tae-Jin Song
International Journal of Surgery.2024; 110(9): 5704. CrossRef
Inequality in Mortality and Cardiovascular Risk Among Young, Low-Income, Self-Employed Workers: Nationwide Retrospective Cohort Study
Byungyoon Yun, Heejoo Park, Jaesung Choi, Juyeon Oh, Juho Sim, Yangwook Kim, Jongmin Lee, Jin-Ha Yoon
JMIR Public Health and Surveillance.2024; 10: e48047. CrossRef
Changes in seasonality and sex ratio of scrub typhus: a case study of South Korea from 2003 to 2019 based on wavelet transform analysis
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BMC Infectious Diseases.2024;[Epub] CrossRef
SGLT2 Inhibitor Use and Risk of Dementia and Parkinson Disease Among Patients With Type 2 Diabetes
Hae Kyung Kim, Geert Jan Biessels, Min Heui Yu, Namki Hong, Yong-ho Lee, Byung-Wan Lee, Eun Seok Kang, Bong-Soo Cha, Eun Jig Lee, Minyoung Lee
Neurology.2024;[Epub] CrossRef
Metabolic Dysfunction-Associated Steatotic Liver Disease Is Associated with Increased Risk of Kidney Cancer: A Nationwide Study
Juyeon Oh, Beom Kyung Kim, Jin-Ha Yoon, Hyung Ho Lee, Heejoo Park, Jian Lee, Youngsun Park, Byungyoon Yun, Jinsoo Chung
Cancers.2024; 16(18): 3161. CrossRef
Moyamoya Disease increased the risk of Retinal Vascular Occlusion: A Nationwide Cohort Study in Korea
Min Seok Kim, Seonghee Nam, Si Un Lee, Sang Jun Park, Se Joon Woo, Jeongwoo Lee, Kwangsic Joo
Ophthalmology Retina.2024;[Epub] CrossRef
Non-Alcoholic Fatty Liver Disease and Its Association with Kidney and Cardiovascular Outcomes in Moderate to Advanced Chronic Kidney Disease
Cheol Ho Park, Hyunsun Lim, Youn Nam Kim, Jae Young Kim, Hyung Woo Kim, Tae Ik Chang, Seung Hyeok Han
American Journal of Nephrology.2024; : 1. CrossRef
High-Volume Hospital Had Lower Mortality of Severe Intracerebral Hemorrhage Patients
Sang-Won Park, James Jisu Han, Nam Hun Heo, Eun Chae Lee, Dong-Hun Lee, Ji Young Lee, Boung Chul Lee, Young Wha Lim, Gui Ok Kim, Jae Sang Oh
Journal of Korean Neurosurgical Society.2024; 67(6): 622. CrossRef
Association between colchicine use and adverse cardiovascular events in patients with gout: a nationwide nested case–control study
Hyung Woo Kim, Minjin Kang, Hyunsun Lim, Cheol Ho Park, Jae Young Kim, Tae Ik Chang, Seung Hyeok Han
Rheumatology.2024;[Epub] CrossRef
Impact of Chronic Kidney Disease and Gout on End-Stage Renal Disease in Type 2 Diabetes: Population-Based Cohort Study
Inha Jung, Da Young Lee, Seung Min Chung, So Young Park, Ji Hee Yu, Jun Sung Moon, Ji A Seo, Kyungdo Han, Nan Hee Kim
Endocrinology and Metabolism.2024; 39(5): 748. CrossRef
Nationwide Trends in Helicobacter pylori Eradication Therapies in Korea: Impact of Guideline Updates on Treatment Practices
Byung Wook Jung, Yun Jin Kim, Chan Hyuk Park
Helicobacter.2024;[Epub] CrossRef
Incidence and prevalence of seropositive rheumatoid arthritis among Korean women of childbearing age: a nationwide population-based study
Min Kyung Chung, Chan Hee Lee, Jin Su Park, Hyun Sun Lim, Jisoo Lee
The Korean Journal of Internal Medicine.2023; 38(1): 125. CrossRef
Myth and Truth in Opioid Consumption with Intrathecal Morphine Pump Implantation in Chronic Pain: A Retrospective Cohort Study with Claims Database in South Korea
Yongjae Yoo, Joo Hyeon Oh, Haine Lee, Hyunsook Choi, Somin Joo, Andrew Hogyu Han, Jee Youn Moon
Pain Medicine.2023; 24(1): 79. CrossRef
Epidemiology of idiopathic sudden sensorineural hearing loss in the era of big data
Chul Young Yoon, Tae Hoon Kong, Juhyung Lee, Young Joon Seo, Jae Joon Ahn
European Archives of Oto-Rhino-Laryngology.2023; 280(5): 2181. CrossRef
Allergic Diseases and Risk of Incident Dementia and Alzheimer's Disease
Hee‐Kyung Joh, Hyuktae Kwon, Ki Young Son, Jae Moon Yun, Su Hwan Cho, Kyungdo Han, Jin‐Ho Park, Belong Cho
Annals of Neurology.2023; 93(2): 384. CrossRef
Post-operative recurrence of liver cancer according to antiviral therapy for detectable hepatitis B viremia: A nationwide study
Byungyoon Yun, Sang Hoon Ahn, Juyeon Oh, Jin-Ha Yoon, Beom Kyung Kim
European Journal of Internal Medicine.2023; 107: 66. CrossRef
Comparable Mortality Between Asian Patients with Chronic Hepatitis B Under Long-Term Antiviral Therapy vs Matched Control: A Population-Based Study
Byungyoon Yun, Juyeon Oh, Sang Hoon Ahn, Jin-Ha Yoon, Beom Kyung Kim
American Journal of Gastroenterology.2023; 118(6): 1001. CrossRef
Body mass index, waist circumference and cardiovascular diseases in transitional ages (40 and 66 years)
Jung Eun Yoo, Kyungdo Han, Jin‐Hyung Jung, Yang‐Im Hur, Yang Hyun Kim, Eun Sook Kim, Jang Won Son, Eun‐Jung Rhee, Won‐Young Lee, Ga Eun Nam
Journal of Cachexia, Sarcopenia and Muscle.2023; 14(1): 369. CrossRef
Waist circumference and end‐stage renal disease based on glycaemic status: National Health Insurance Service data 2009–2018
Yun Kyung Cho, Ji Hye Huh, Shinje Moon, Yoon Jung Kim, Yang‐Hyun Kim, Kyung‐do Han, Jun Goo Kang, Seong Jin Lee, Sung‐Hee Ihm
Journal of Cachexia, Sarcopenia and Muscle.2023; 14(1): 585. CrossRef
Comparison of Trends in the Incidence of Traumatic Spinal Cord Injury in Daily Life, Automobile Accidents, and Industrial Accidents: A National Multi-Insurance Study in Korea
Yoonjeong Choi, Young-Eun Kim, Ja-Ho Leigh, Ye Seol Lee, Han-Kyoul Kim, You Gyoung Yi, Jinyoung Lee, Min-Yong Lee, Gangpyo Lee, Hyung-Ik Shin, Moon Suk Bang
Journal of Korean Medical Science.2023;[Epub] CrossRef
A population-based study on the risk of prescription opioid abuse in patients with chronic opioid use and cost-effectiveness of prescription drug monitoring program using a patient simulation model in South Korea
Siin Kim, Hae Sun Suh
International Journal of Drug Policy.2023; 112: 103953. CrossRef
The effects of sociodemographic factors on help-seeking for depression: Based on the 2017–2020 Korean Community Health Survey
JinYoung Lee, Kyeong-Sook Choi, Ji-Ae Yun, Pedro Vieira da Silva Magalhaes
PLOS ONE.2023; 18(1): e0280642. CrossRef
Efficacy of acupuncture on cardiovascular complications in patients with diabetes mellitus in Korea: A nationwide retrospective cohort
Hyejin Jung, Tiana Won, Ga-Yeon Kim, Jowon Jang, Sujung Yeo, Sabina Lim
Journal of Integrative Medicine.2023; 21(2): 176. CrossRef
A 12-year nationwide cohort study on the association between central retinal artery occlusion and cancer
Min Seok Kim, Seong Jun Byun, Se Joon Woo, Kyu Hyung Park, Sang Jun Park
Graefe's Archive for Clinical and Experimental Ophthalmology.2023;[Epub] CrossRef
Long-Term Nonoperative Management is Associated With Lower Mean 9-Year Follow-Up Survival Compared to Total Knee Arthroplasty in Knee Osteoarthritis Patients—Survival Analysis of a Nationwide South Korean Cohort
Hyein Han, Du Hyun Ro, Sungho Won, Hyuk-Soo Han
The Journal of Arthroplasty.2023; 38(8): 1470. CrossRef
Positive faecal immunochemical test predicts the onset of inflammatory bowel disease: A nationwide, propensity score-matched study
Eunyoung Lee, Gil Ho Lee, Bumhee Park, Sung Soo Ahn, Choong-Kyun Noh
Frontiers in Immunology.2023;[Epub] CrossRef
Scheduling and Predictive Maintenance for Smart Toilet
Amar Lokman, R. Kanesaraj Ramasamy, Choo-Yee Ting
IEEE Access.2023; 11: 17983. CrossRef
Incidence of Retinal Artery Occlusion and Related Mortality in Korea, 2005 to 2018
Daniel Duck-Jin Hwang, Kyung-Eun Lee, Yuwon Kim, Myoung-Suk Kim, Tyler Hyungtaek Rim, Mina Kim, Hasung Kim, Dae-Sung Kyoung, Ji In Park
JAMA Network Open.2023; 6(3): e233068. CrossRef
Association of general and central obesity, and their changes with risk of knee osteoarthritis: a nationwide population-based cohort study
Dojoon Park, Yong-Moon Park, Seung-Hyun Ko, Kang-Se Hyun, Youn-Ho Choi, Dong-Uk Min, Kyungdo Han, Hae-Seok Koh
Scientific Reports.2023;[Epub] CrossRef
Prior Lifestyle and Survival Outcomes After Intensive Care Unit Admission
In-Ae Song, Tak Kyu Oh
Journal of Korean Medical Science.2023;[Epub] CrossRef
Histamine-2 Receptor Antagonists and Proton Pump Inhibitors Are Associated With Reduced Risk of SARS-CoV-2 Infection Without Comorbidities Including Diabetes, Hypertension, and Dyslipidemia: A Propensity Score-Matched Nationwide Cohort Study
Bokyung Kim, Jin-Hyung Jung, Kyungdo Han, Seungkyung Kang, Eunwoo Lee, Hyunsoo Chung, Sang Gyun Kim, Soo-Jeong Cho
Journal of Korean Medical Science.2023;[Epub] CrossRef
Blood pressure and dementia risk by physical frailty in the elderly: a nationwide cohort study
Mi Hee Cho, Kyungdo Han, Seungwoo Lee, Su-Min Jeong, Jung Eun Yoo, SangYun Kim, Jinkook Lee, Sohyun Chun, Dong Wook Shin
Alzheimer's Research & Therapy.2023;[Epub] CrossRef
Increased risk of cardiovascular disease associated with diabetes among adult cancer survivors: a population-based matched cohort study
Sanghyun Oh, Jihwan Lee, Yoo S Hong, Kyuwoong Kim
European Journal of Preventive Cardiology.2023; 30(8): 670. CrossRef
Association between familial aggregation of chronic kidney disease and its incidence and progression
Jae Young Kim, Sung-youn Chun, Hyunsun Lim, Tae Ik Chang
Scientific Reports.2023;[Epub] CrossRef
Participation and Prognostic Impact of Cardiac Rehabilitation After Acute Coronary Syndrome: Big-Data Study of the Korean National Health Insurance Service
Hee-Eun Choi, Chul Kim, Da-Jung Lee, Jae-Eun Joo, Ho-Seob Kim
Journal of Korean Medical Science.2023;[Epub] CrossRef
Analysis of Anxiety or Depression and Long-term Mortality Among Survivors of Out-of-Hospital Cardiac Arrest
Juncheol Lee, Yongil Cho, Jaehoon Oh, Hyunggoo Kang, Tae Ho Lim, Byuk Sung Ko, Kyung Hun Yoo, Sang Hwan Lee
JAMA Network Open.2023; 6(4): e237809. CrossRef
Treatment Changes and Prognoses in Patients with Incident Drug-Induced Parkinsonism Using a Korean Nationwide Healthcare Claims Database
Siin Kim, Hae Sun Suh
Journal of Clinical Medicine.2023; 12(8): 2860. CrossRef
Trends in the Incidence and Etiology of Non-Traumatic Spinal Cord Injury in Korea: A Nationwide Population-Based Study From 2007 to 2020
Yoonjeong Choi, Ja-Ho Leigh, Jooeun Jeon, Goo Joo Lee, Hyung-Ik Shin, Moon Suk Bang
Journal of Korean Medical Science.2023;[Epub] CrossRef
The Association between Metabolic Syndrome and Epithelial Cell Abnormalities Detected on Pap Smear: A Nationwide Population-Based Study
Dayong Lee, Taek Sang Lee
Journal of Clinical Medicine.2023; 12(8): 2954. CrossRef
Long‐term adverse neurodevelopmental outcomes of discordant twins delivered at term: A nationwide population‐based study
Eun‐Saem Choi, Young Mi Jung, Kyu‐Dong Cho, Sungyeon Ha, Jeongwon Sohn, Su Jung Hong, Min‐Jeong Oh, Chan‐Wook Park, Joong Shin Park, Jong Kwan Jun, Seung Mi Lee, Geum Joon Cho
BJOG: An International Journal of Obstetrics & Gynaecology.2023; 130(11): 1370. CrossRef
Cancer and Mortality Risks of Graves’ Disease in South Korea Based on National Data from 2010 to 2019
Young Ju Choi, Kyungdo Han, Won Kyoung Cho, Min Ho Jung, Byung-Kyu Suh
Clinical Epidemiology.2023; Volume 15: 535. CrossRef
Association of Waist Circumference with the Risk of Inflammatory Bowel Disease: a Nationwide Cohort Study of 10 Million Individuals in Korea
Yeonjin Je, Kyungdo Han, Jaeyoung Chun, Yuna Kim, Jie-Hyun Kim, Young Hoon Youn, Hyojin Park, Jong Pil Im, Joo Sung Kim
Journal of Crohn's and Colitis.2023; 17(5): 681. CrossRef
Lifestyle factors and long-term survival in patients with chronic non-cancer pain: a nationwide cohort study in South Korea
Tak Kyu Oh, In-Ae Song
Journal of Anesthesia.2023; 37(4): 522. CrossRef
Long term renal outcome after hypertensive disease during pregnancy: a nationwide population-based study
Kwang Hyun Lee, Ji Hye Bae, Jeesun Lee, Young Mi Jung, Chan-Wook Park, Joong Shin Park, Jong Kwan Jun, Geum Joon Cho, Seung Mi Lee
Obstetrics & Gynecology Science.2023; 66(3): 190. CrossRef
Lower risk of depression after smoking cessation and alcohol abstinence in patients with gastric cancer who underwent gastrectomy: A population‐based, nationwide cohort study
Bokyung Kim, Kyungdo Han, Hyunsoo Chung, Sang Gyun Kim, Soo‐Jeong Cho
Cancer.2023; 129(18): 2893. CrossRef
Acute Pancreatitis and the Risk of Dementia in Diabetes: A Nationwide Cohort Study Using Korean Healthcare Claims Database
Woo Hyun Paik, Dong Kee Jang, Soyoung Cho, Jin Ho Choi, Min Kyu Kim, In Rae Cho, Ji Kon Ryu, Yong-Tae Kim, Kyung-Do Han, Sang Hyub Lee
Journal of Alzheimer's Disease.2023; 94(1): 205. CrossRef
Application of big data in ophthalmology
Zhi Da Soh, Ching-Yu Cheng
Taiwan Journal of Ophthalmology.2023; 13(2): 123. CrossRef
Impact of mental disorders on the risk of heart failure among Korean patients with diabetes: a cohort study
Tae Kyung Yoo, Kyung-Do Han, Eun-Jung Rhee, Won-Young Lee
Cardiovascular Diabetology.2023;[Epub] CrossRef
Evaluating Reference Ages for Selecting Prosthesis Types for Heart Valve Replacement in Korea
Sung Jun Park, You Jung Ok, Ho Jin Kim, Ye-Jee Kim, Seonok Kim, Jung-Min Ahn, Dae-Hee Kim, Jae-Sung Choi, Joon Bum Kim
JAMA Network Open.2023; 6(5): e2314671. CrossRef
Higher Non-High-Density Lipoprotein Cholesterol Was Higher Associated With Cardiovascular Disease Comparing Higher LDL-C in Nine Years Follow Up: Cohort Study
Sangmo Hong, Kyungdo Han, Jung Hwan Park, Sung Hoon Yu, Chang Beom Lee, Dong Sun Kim
Journal of Lipid and Atherosclerosis.2023; 12(2): 164. CrossRef
Impact of Allergic Disease on the Risk of Mycobacterial Disease
Taehee Kim, Hayoung Choi, Hyun Lee, Kyungdo Han, Dong Won Park, Tai Sun Park, Ji-Yong Moon, Tae-Hyung Kim, Jang Won Sohn, Ho Joo Yoon, Sang-Heon Kim
The Journal of Allergy and Clinical Immunology: In Practice.2023; 11(9): 2830. CrossRef
Trends in the Prevalence of Blindness and Correlation With Health Status in Korean Adults: A 10-Year Nationwide Population-Based Study
Kyeong Ik Na, Won June Lee, Young Kook Kim
Journal of Korean Medical Science.2023;[Epub] CrossRef
Association between regular physical activity and lower incidence of colorectal cancer in patients with diabetes mellitus: a nationwide cohort study
Han Hee Lee, Kyu‐na Lee, Jin Su Kim, Dae Young Cheung, Hyuk‐Sang Kwon, Bo‐In Lee, Young‐Seok Cho, Soo‐Heon Park, Kyungdo Han, Jin Il Kim
Colorectal Disease.2023; 25(8): 1588. CrossRef
Bovine pericardial versus porcine bioprosthetic mitral valves: results from a Korean Nationwide Cohort Study
Hong Rae Kim, Jino Park, Sung Jun Park, Ho Jin Kim, Seonok Kim, Ye-Jee Kim, Jung-Min Ahn, Dae-Hee Kim, Joon Bum Kim
European Journal of Cardio-Thoracic Surgery.2023;[Epub] CrossRef
Examining the factors associated with inpatients’ perception of overtreatment in Korea: a cross-sectional study
Jin Su Jang, Hyun Woo Jung
BMC Health Services Research.2023;[Epub] CrossRef
Long-term clinical outcomes of tricuspid valve replacement using bovine versus porcine valves: a nationwide population-based study
Suk Ho Sohn, Yoonjin Kang, Ji Seong Kim, Ho Young Hwang, Kyung Hwan Kim, Jae Woong Choi
European Journal of Cardio-Thoracic Surgery.2023;[Epub] CrossRef
Association of physical activity with total and cause-specific mortality in patients with diabetes: A nationwide population-based cohort study
Inha Jung, Kyung-Do Han, Sun Joon Moon, Hyemi Kwon, Se Eun Park, Eun-Jung Rhee, Won-Young Lee
Diabetes Research and Clinical Practice.2023; 202: 110819. CrossRef
The Association Between Institutional Case Volume of Hematopoietic Stem Cell Transplantation and Mortality
Leerang Lim, Eun Jin Jang, Jun Woo Jo, Junghoon Shin, Hyobin Lee, Hannah Lee, Seung-Young Oh, Hyunjae Im, Ho Geol Ryu
Transplantation Proceedings.2023; 55(7): 1715. CrossRef
Association between periodontal disease status and risk of atrial fibrillation: a nationwide population-based cohort study
Jung-Hyun Park, Hyungwoo Lee, Jin-Woo Kim, Tae-Jin Song
BMC Oral Health.2023;[Epub] CrossRef
Trends in the incidence and prevalence of dysphagia requiring medical attention among adults in South Korea, 2006–2016: A nationwide population study
SuYeon Kwon, Seungwoo Cha, Junsik Kim, Kyungdo Han, Nam-Jong Paik, Won-Seok Kim, Sina Azadnajafabad
PLOS ONE.2023; 18(6): e0287512. CrossRef
Socioeconomic Disparities in the Association Between All-Cause Mortality and Health Check-Up Participation Among Healthy Middle-Aged Workers: A Nationwide Study
Byungyoon Yun, Juyeon Oh, Jaesung Choi, Laura S. Rozek, Heejoo Park, Juho Sim, Yangwook Kim, Jongmin Lee, Jin-Ha Yoon
Journal of Korean Medical Science.2023;[Epub] CrossRef
Association between smoking status and death from COVID-19 in South Korea: A nationwide cohort study
Jae Woo Choi
Tobacco Induced Diseases.2023; 21(July): 1. CrossRef
A cohort study found a high risk of end-stage kidney disease associated with acromegaly
Sangmo Hong, Kyung-Soo Kim, Kyungdo Han, Cheol-Young Park
Kidney International.2023; 104(4): 820. CrossRef
Comparative cardiovascular outcomes in type 2 diabetes patients taking dapagliflozin versus empagliflozin: a nationwide population-based cohort study
Jaehyun Lim, You-Jung Choi, Bong Sung Kim, Tae-Min Rhee, Hyun-Jung Lee, Kyung-Do Han, Jun-Bean Park, Jin Oh Na, Yong-Jin Kim, Heesun Lee, Hyung-Kwan Kim
Cardiovascular Diabetology.2023;[Epub] CrossRef
Effects of Statin Treatment on the Development of Tendinopathy: A Nationwide Population-Based Cohort Study
Donghee Kwak, Seok-joo Moon, Jong Woong Park, Duk Hee Lee, Jung Il Lee
Orthopaedic Journal of Sports Medicine.2023;[Epub] CrossRef
Incident dementia in kidney transplantation recipients: a matched comparative nationwide cohort study in South Korea
Seon Ha Baek, Jina Park, Sehoon Park, Mi-yeon Yu, Ji Eun Kim, Sang Hyun Park, Kyungdo Han, Yong Chul Kim, Dong Ki Kim, Kwon Wook Joo, Yon Su Kim, Hajeong Lee
Kidney Research and Clinical Practice.2023; 42(4): 519. CrossRef
Developing Operational Definitions Related toHelicobacter pyloriEradication Therapy
Chan Hyuk Park, Sun-Young Jung, Ju Won Lee, Hyo-Joon Yang, Joon Sung Kim, Beom Jin Kim, Soo In Choi, Seung In Seo, Joongyub Lee, Jae Gyu Kim
Journal of Korean Medical Science.2023;[Epub] CrossRef
Fracture Risk in Middle-Aged and Older Patients With Inflammatory Bowel Disease: A Korean Nationwide Population-Based Cohort Study
Ji Min Lee, Kyungdo Han, Kang-Moon Lee, Jae-Seung Yun
Journal of Korean Medical Science.2023;[Epub] CrossRef
Sex differences in mortality in patients with acromegaly: a nationwide cohort study in Korea
Jiwon Kim, Namki Hong, Jimi Choi, Ju Hyung Moon, Eui Hyun Kim, Jae Won Hong, Eun Jig Lee, Sin Gon Kim, Cheol Ryong Ku
European Journal of Endocrinology.2023; 189(2): 225. CrossRef
Proton pump inhibitor use and the risk of metachronous gastric cancer after H. pylori eradication in patients who underwent endoscopic resection for gastric neoplasms: A population‐based cohort study
Eun Jeong Gong, Hye‐Kyung Jung, Bora Lee, Jitaek Hong, Jong Wook Kim, Cheol Min Shin, Young Hoon Youn, Kwang Jae Lee
Alimentary Pharmacology & Therapeutics.2023; 58(7): 668. CrossRef
National Trends in Rotavirus Enteritis among Infants in South Korea, 2010–2021: A Nationwide Cohort
Hyun Jee Lee, Yujin Choi, Jaeyu Park, Yong-Sung Choi, Dong Keon Yon, Do Hyun Kim
Children.2023; 10(9): 1436. CrossRef
Impact of Concomitant Use of Proton Pump Inhibitors and Clopidogrel on Recurrent Stroke and Myocardial Infarction
Yong Kang Lee, Hyun Sun Lim, Youn I Choi, Eun Ju Choe, Seonji Kim, Seng Chan You, Kyung Joo Lee, Yerim Kim, Da Hee Park, Woon Geon Shin, Seung In Seo
Pharmaceuticals.2023; 16(9): 1213. CrossRef
Uric Acid and Risk of Cardiovascular Disease and Mortality: A Longitudinal Cohort Study
Jae Young Kim, Changhwan Seo, Haeyong Pak, Hyunsun Lim, Tae Ik Chang
Journal of Korean Medical Science.2023;[Epub] CrossRef
Occupational characteristics and risk factors associated with endometriosis among Korean female workers
Seunghyun Lee, Seung-Yeon Lee, Wanhyung Lee, Federico Romano
PLOS ONE.2023; 18(10): e0292362. CrossRef
Suicidal Thinking Among Patients With Spinal Conditions in South Korea: A Population-Based Cross-Sectional Study
Tak Kyu Oh, Hye Yoon Park, In-Ae Song
Psychiatry Investigation.2023; 20(9): 834. CrossRef
Increased risk of venous and arterial thromboembolism in patients with colorectal cancer receiving cetuximab-based combination chemotherapy: A population-based study in Korea
Ho-Young Yhim, Juhyun Lee, Kyoung Ha Kim, Sang-A Kim, Ji Yun Lee, Hun-Gyu Hwang, Junshik Hong, Jeong-Ok Lee, Soo-Mee Bang
Thrombosis Research.2023; 231: 50. CrossRef
Volatile Anesthetic Use Versus Total Intravenous Anesthesia for Patients Undergoing Heart Valve Surgery: A Nationwide Population-Based Study
Jae-Woo Ju, Ho-Jin Lee, Karam Nam, Seungwook Kim, Hyunsook Hong, Seung Ho Yoo, Seohee Lee, Youn Joung Cho, Yunseok Jeon
Anesthesia & Analgesia.2023;[Epub] CrossRef
Incidence, Morbidity, and Mortality of Achalasia: A Nationwide, Population-Based Cohort Study in South Korea
Ga Hee Kim, Hyungchul Park, Kee Wook Jung, Min-Ju Kim, Ye-Jee Kim, Ji Min Lee, Bong Eun Lee, Yang Won Min, Jeong Hwan Kim, Hee Kyong Na, Ji Yong Ahn, Jeong Hoon Lee, Do Hoon Kim, Kee Don Choi, Ho June Song, Gin Hyug Lee, Hwoon-Yong Jung, Hyun Jin Kim
Gut and Liver.2023; 17(6): 894. CrossRef
Differential Impact of Obesity on the Risk of Diabetes Development in Two Age Groups: Analysis from the National Health Screening Program
Tae Kyung Yoo, Kyung-Do Han, Yang-Hyun Kim, Ga Eun Nam, Sang Hyun Park, Eun-Jung Rhee, Won-Young Lee
Diabetes & Metabolism Journal.2023; 47(6): 846. CrossRef
Association between preoperative modifiable lifestyle factors and mortality after cancer surgery: a population-based cohort study in South Korea
Tak Kyu Oh, In-Ae Song
Annals of Surgical Treatment and Research.2023; 105(4): 179. CrossRef
Classification of long-term clinical course of Parkinson’s disease using clustering algorithms on social support registry database
Dougho Park, Su Yun Lee, Jong Hun Kim, Hyoung Seop Kim
Journal of Big Data.2023;[Epub] CrossRef
Association between Proteinuria Status and Risk of Hypertension: A Nationwide Population-Based Cohort Study
Hyungwoo Lee, Moo-Suk Park, Min Kyoung Kang, Tae-Jin Song
Journal of Personalized Medicine.2023; 13(9): 1414. CrossRef
Association of physical activity with the risk of Parkinson's disease in depressive disorder: A nationwide longitudinal cohort study
Ji hyun An, Kyung-do Han, Jin-Hyung Jung, Hong Jin Jeon
Journal of Psychiatric Research.2023; 167: 93. CrossRef
Effect of changes in the hearing aid subsidy on the prevalence of hearing loss in South Korea
Chul Young Yoon, Junhun Lee, Tae Hoon Kong, Young Joon Seo
Frontiers in Neurology.2023;[Epub] CrossRef
Preoperative Body Mass Index, Waist Circumference, and Mortality After Major Cancer Surgery: A Nationwide Cohort Study in Korea
Tak Kyu Oh, In-Ae Song
Journal of Korean Medical Science.2023;[Epub] CrossRef
Characteristics and risk factors of suicide among people who attempted self-harm in South Korea: A longitudinal National Cohort Study in South Korea
Hye Hyeon Kim, Jin Hyuk Lee, In Han Song, Yu Rang Park
Psychiatry Research.2023; 330: 115613. CrossRef
Association Between Premature Menopause and Cardiovascular Diseases and All‐Cause Mortality in Korean Women
Gyu Bae Lee, Ga Eun Nam, Wonsock Kim, Byoungduck Han, Kyung Hwan Cho, Seon Mee Kim, Youn Seon Choi, Do Hoon Kim, Yong‐Gyu Park, Jin‐Hyung Jung, Kyungdo Han, Yang‐Hyun Kim
Journal of the American Heart Association.2023;[Epub] CrossRef
Risk of gastric cancer among long-term proton pump inhibitor users: a population-based cohort study
Jong Wook Kim, Hye-Kyung Jung, Bora Lee, Cheol Min Shin, Eun Jeong Gong, Jitaek Hong, Young Hoon Youn, Kwang Jae Lee
European Journal of Clinical Pharmacology.2023; 79(12): 1699. CrossRef
Cancer Risk in Elderly Korean Patients with Neurodegenerative Disease and its relation to Type 2 Diabetes
Hee-Cheol Kim, Ji-Hun Kim, Ho-Jun Lee, Yang-Tae Kim, Byeong-Churl Jang
The Open Neurology Journal.2023;[Epub] CrossRef
Performance of Cardiovascular Risk Prediction Models in Korean Patients With New‐Onset Rheumatoid Arthritis: National Cohort Study
Jae Hyun Kim, Gaeun Lee, Jinseub Hwang, Ji‐Won Kim, Jin‐Won Kwon, Yun‐Kyoung Song
Journal of the American Heart Association.2023;[Epub] CrossRef
Impact of Propofol-based Total Intravenous Anesthesia Versus Inhalation Anesthesia on Long-term Survival After Cancer Surgery in a Nationwide Cohort
Susie Yoon, Sun-Young Jung, Myo-Song Kim, Danbi Yoon, Younghae Cho, Yunseok Jeon
Annals of Surgery.2023; 278(6): 1024. CrossRef
Decreased Risk of Knee Osteoarthritis with Taller Height in an East Asian Population: A Nationwide Cohort Study
Dong Hwan Lee, Hwa Sung Lee, Soo Hyun Jang, Jun-Young Heu, Kyungdo Han, Se-Won Lee
Journal of Clinical Medicine.2023; 13(1): 92. CrossRef
Cost-effectiveness of the anti-vascular endothelial growth factor intravitreal injection and panretinal photocoagulation for patients with proliferative diabetic retinopathy in South Korea
Hyeon-Jeong Lee, Songhee Cho, Jungeun Park, Yan Jin, Hyung Min Kim, Donghyun Jee
BMC Health Services Research.2023;[Epub] CrossRef
Prior Evaluation of Nutritional Status and Mortality in Patients with Sepsis in South Korea
Tak Kyu Oh, In-Ae Song
Nutrients.2023; 15(24): 5040. CrossRef
Increased Risk of Hip Fracture in Patients with Acromegaly: A Nationwide Cohort Study in Korea
Jiwon Kim, Namki Hong, Jimi Choi, Ju Hyung Moon, Eui Hyun Kim, Eun Jig Lee, Sin Gon Kim, Cheol Ryong Ku
Endocrinology and Metabolism.2023; 38(6): 690. CrossRef
Cancer risks in patients with ankylosing spondylitis and the effects of biologic agents: a population-based study
Sang-Yong Eom, Hyun-a Jang, Yo Han Im, Kyung-Hwa Choi, Ji Hyoun Kim
Rheumatology.2023;[Epub] CrossRef
Real-World Impact of Modern Reperfusion Therapy for Acute Ischemic Stroke : A Nationwide Population-Based Data Study in Korea
Yung Ki Park, Byul-Hee Yoon, Yu Deok Won, Jae Hoon Kim, Hee In Kang
Journal of Korean Neurosurgical Society.2023;[Epub] CrossRef
Proton Pump Inhibitor Co-Therapy in Patients with Atrial Fibrillation Treated with Oral Anticoagulants and a Prior History of Upper Gastrointestinal Tract Bleeding
So-Ryoung Lee, Soonil Kwon, Eue-Keun Choi, Jin-Hyung Jung, Kyung-Do Han, Seil Oh, Gregory Y. H. Lip
Cardiovascular Drugs and Therapy.2022; 36(4): 679. CrossRef
Institutional case volume-incorporated mortality risk prediction model for cardiac surgery
Seohee Lee, Eun Jin Jang, Junwoo Jo, Dongnyeok Park, Ho Geol Ryu
Asian Journal of Surgery.2022; 45(1): 189. CrossRef
Does Surgical Ablation of Atrial Fibrillation Benefit Patients Undergoing Bioprosthetic Valve Replacement?
Won Kyung Pyo, Ho Jin Kim, Joon Bum Kim, Sung-Ho Jung, Suk Jung Choo, Cheol Hyun Chung, Jae Won Lee
Seminars in Thoracic and Cardiovascular Surgery.2022; 34(3): 906. CrossRef
Burden of comorbidities and medication use in childbearing women with rheumatic diseases: a nationwide population-based study
Min Kyung Chung, Chan Hee Lee, Jin Su Park, Hyunsun Lim, Jisoo Lee
The Korean Journal of Internal Medicine.2022; 37(6): 1250. CrossRef
Validation of Dynamic Aspartate‐to–Alanine Aminotransferase Ratio for Predicting Liver Disease Mortality
In‐Ae Song, Eun Sun Jang, Tak Kyu Oh
Hepatology Communications.2022; 6(4): 740. CrossRef
Blood Pressure Levels and Risks of Dementia: a Nationwide Study of 4.5 Million People
Chan Joo Lee, Ji-Yeon Lee, Kyungdo Han, Da Hye Kim, Hanna Cho, Kwang Joon Kim, Eun Seok Kang, Bong-Soo Cha, Yong-ho Lee, Sungha Park
Hypertension.2022; 79(1): 218. CrossRef
Continuing regular physical activity and maintaining body weight have a synergistic interaction in improving survival: a population-based cohort study including 6.5 million people
Chang-Hoon Lee, Kyung-Do Han, Da Hye Kim, Min-Sun Kwak
European Journal of Preventive Cardiology.2022; 29(3): 547. CrossRef
Liver enzymes and risk of ocular motor cranial nerve palsy: a nationwide population-based study
Joonhyoung Kim, Kyungdo Han, Juhwan Yoo, Kyung-Ah Park, Sei Yeul Oh
Neurological Sciences.2022; 43(5): 3395. CrossRef
Underutilisation of prophylactic G-CSF in breast cancer patients receiving adjuvant docetaxel/cyclophosphamide chemotherapy
Minhee Ku, Nam Kyung Je
Journal of Chemotherapy.2022; 34(8): 534. CrossRef
Epidemiologic study of bladder and urethral injury in Korea: A nationwide population-based study
Bum Sik Tae, Young Eun Yoon, Woong Na, Kyung Jin Oh, Sung Yul Park, Jae Young Park, Hong Sang Moon
Investigative and Clinical Urology.2022; 63(1): 92. CrossRef
Acromegaly and cardiovascular outcomes: a cohort study
Sangmo Hong, Kyung-Soo Kim, Kyungdo Han, Cheol-Young Park
European Heart Journal.2022; 43(15): 1491. CrossRef
Pericardial Versus Porcine Valves for Surgical Aortic Valve Replacement
Hong Ju Shin, Wan Kee Kim, Jin Kyoung Kim, Joon Bum Kim, Sung-Ho Jung, Suk Jung Choo, Cheol Hyun Chung, Jae Won Lee
Korean Circulation Journal.2022; 52(2): 136. CrossRef
Effect of obesity and metabolic health on urolithiasis: A nationwide population-based study
Changil Choi, Jong Keun Kim, Kyungdo Han, Young Goo Lee, Jun Hyun Han
Investigative and Clinical Urology.2022; 63(1): 63. CrossRef
Comprehensive risk assessment for hospital-acquired pneumonia: sociodemographic, clinical, and hospital environmental factors associated with the incidence of hospital-acquired pneumonia
Bo-Guen Kim, Minwoong Kang, Jihyun Lim, Jin Lee, Danbee Kang, Minjung Kim, Jinhee Kim, Hyejeong Park, Kyung Hoon Min, Juhee Cho, Kyeongman Jeon
BMC Pulmonary Medicine.2022;[Epub] CrossRef
Metabolic Disease Incidence After Allogeneic Stem Cell Transplantation: A Nationwide Korean Case-Control Study
Jeonghoon Ha, See Hyun Park, Sung-Soo Park, Seunghoon Han
The Journal of Clinical Endocrinology & Metabolism.2022; 107(4): 943. CrossRef
Development of eClaim system for private indemnity health insurance in South Korea: Compatibility and interoperability
Sungchul Bae, Byoung-Kee Yi
Health Informatics Journal.2022;[Epub] CrossRef
Incidence of Depression after Traumatic Brain Injury: A Nationwide Longitudinal Study of 2.2 Million Adults
Yoonjeong Choi, Eun Young Kim, Jiyu Sun, Han-Kyoul Kim, Ye Seol Lee, Byung-Mo Oh, Hye Yoon Park, Ja-Ho Leigh
Journal of Neurotrauma.2022; 39(5-6): 390. CrossRef
Female Reproductive Factors and the Risk of Bronchiectasis: A Nationwide Population-Based Longitudinal Study
Bumhee Yang, Dong-Hwa Lee, Kyungdo Han, Hayoung Choi, Hyung Koo Kang, Dong Wook Shin, Hyun Lee
Biomedicines.2022; 10(2): 303. CrossRef
Clinical outcomes of early closure versus conservative strategy after diagnosis with atrial septal defect: a nationwide population-based cohort study
Sun-Yang Min, Ji Sung Lee, Duk-Woo Park, Jong-Min Song
European Journal of Cardio-Thoracic Surgery.2022;[Epub] CrossRef
Risk of Osteoporotic Fractures Among Obese Women Based on Body Mass Index and Waist Circumference: A Nationwide Cohort in South Korea
Gyeongsil Lee, Seulggie Choi, Yoosun Cho, Sang Min Park
Clinical Nutrition Research.2022; 11(1): 32. CrossRef
Long-term prognosis and causes of death among survivors after out-of-hospital cardiac arrest: A population-based longitudinal study
Yongil Cho, Jaehoon Oh, Jeong-Hun Shin, Byung Sik Kim, Jin-Kyu Park, Jun Ho Lee, Jae Hwan Kim, Minae Park
Resuscitation.2022; 173: 31. CrossRef
Blood pressure and mortality after percutaneous coronary intervention: a population-based cohort study
Chung-woo Lee, Joo Kyung Lee, Yeon Joo Choi, Hyunjin Kim, Kyungdo Han, Jin-hyung Jung, Do Hoon Kim, Joo-Hyun Park
Scientific Reports.2022;[Epub] CrossRef
Analysis of Severe Hypoglycemia Among Adults With Type 2 Diabetes and Nonalcoholic Fatty Liver Disease
Ji-Yeon Lee, Young-eun Kim, Kyungdo Han, Eugene Han, Byung Wan Lee, Eun Seok Kang, Bong-Soo Cha, Seung-Hyun Ko, Yong-ho Lee
JAMA Network Open.2022; 5(2): e220262. CrossRef
Hip Fracture Risk According to Diabetic Kidney Disease Phenotype in a Korean Population
Seung Eun Lee, Juhwan Yoo, Kyoung-Ah Kim, Kyungdo Han, Han Seok Choi
Endocrinology and Metabolism.2022; 37(1): 148. CrossRef
Non-Alcoholic Fatty Liver Disease Defined by Fatty Liver Index and Incidence of Heart Failure in the Korean Population: A Nationwide Cohort Study
Byoungduck Han, Gyu Bae Lee, Sun Young Yim, Kyung-Hwan Cho, Koh Eun Shin, Jung-Hwan Kim, Yong-Gyu Park, Kyung-Do Han, Yang-Hyun Kim
Diagnostics.2022; 12(3): 663. CrossRef
Contact with the health care system prior to suicide: A nationwide population-based analysis using linkage national death certificates and national health insurance data
Eun Jee Park, Nam Ju Ji, Weon Young Lee
Journal of Psychiatric Research.2022; 149: 226. CrossRef
Association between asthma or chronic obstructive pulmonary disease and chronic otitis media
Sung Kyun Kim, Seok Jin Hong, Dae Myoung Yoo, Chanyang Min, Hyo Geun Choi
Scientific Reports.2022;[Epub] CrossRef
Prognosis of pregnancy after breast cancer diagnosis according to the type of treatment: A population-based study in Korea by the SMARTSHIP group
Soo Youn Bae, Jihyoun Lee, Ji Sung Lee, Jae Sun Yoon, Ku Sang Kim, Yoo Seok Kim, Zisun Kim, Jun Won Min, Eun-Jung Shim, Ilkyun Lee, Min Hyuk Lee, Sungmin Park
The Breast.2022; 63: 46. CrossRef
Fracture risk and impact of osteoporosis in patients with Parkinson’s disease: a nationwide database study
Tae-lim Kim, Seong Jun Byun, Min Yong Seong, Byung-Mo Oh, Sang Jun Park, Han Gil Seo
Journal of Bone and Mineral Metabolism.2022; 40(4): 602. CrossRef
Risk prediction models incorporating institutional case volume for mortality after hip fracture surgery in the elderly
Seokha Yoo, Eun Jin Jang, Junwoo Jo, Hannah Lee, Yoonbin Hwang, Ho Geol Ryu
Archives of Orthopaedic and Trauma Surgery.2022; 143(5): 2307. CrossRef
Association of weight change following smoking cessation with the risk of tuberculosis development: A nationwide population-based cohort study
Seung Hoon Kim, Yong-Moon Park, Kyungdo Han, Seung Hyun Ko, Shin Young Kim, So Hyang Song, Chi Hong Kim, Kyu Yeon Hur, Sung Kyoung Kim, Juan F. Orueta
PLOS ONE.2022; 17(4): e0266262. CrossRef
Epidemiology of Acute Leukemia among Children with Down Syndrome in Korea
Young Bae Choi, Keon Hee Yoo
Cancer Research and Treatment.2022; 54(2): 572. CrossRef
The Effect of Alcohol Drinking on Metabolic Syndrome and Obesity in Koreans: Big Data Analysis
Eun Jung Park, Hye Jung Shin, Sung Soo Kim, Ki Eun Kim, Sun Hyun Kim, Youl Ri Kim, Kyong Mee Chung, Kyung Do Han
International Journal of Environmental Research and Public Health.2022; 19(9): 4949. CrossRef
Prolonged or Transition to Metabolically Unhealthy Status, Regardless of Obesity Status, Is Associated with Higher Risk of Cardiovascular Disease Incidence and Mortality in Koreans
Juhee Lee, So-Young Kwak, Dahyun Park, Ga-Eun Kim, Clara Yongjoo Park, Min-Jeong Shin
Nutrients.2022; 14(8): 1644. CrossRef
Lifestyle, body mass index, diabetes, and the risk of pancreatic cancer in a nationwide population-based cohort study with 7.4 million Korean subjects
Byung Kyu Park, Jeong Hun Seo, Jae Bock Chung, Jung Kyu Choi
British Journal of Cancer.2022; 127(3): 549. CrossRef
Cardiovascular Risk and Treatment Outcomes in Severe Hypercholesterolemia: A Nationwide Cohort Study
Chan Joo Lee, Sanghyun Park, Kyungdo Han, Sang‐Hak Lee
Journal of the American Heart Association.2022;[Epub] CrossRef
Association between Smoking Status and Incident Non-Cystic Fibrosis Bronchiectasis in Young Adults: A Nationwide Population-Based Study
Bumhee Yang, Kyungdo Han, Bongseong Kim, Hyung Koo Kang, Jung Soo Kim, Eung-Gook Kim, Hayoung Choi, Hyun Lee
Journal of Personalized Medicine.2022; 12(5): 691. CrossRef
Clinical Indication of Aspirin Associated With Reduced Risk of Liver Cancer in Chronic Hepatitis B: A Nationwide Cohort Study
Byungyoon Yun, Sang Hoon Ahn, Jin-Ha Yoon, Beom Kyung Kim
American Journal of Gastroenterology.2022; 117(5): 758. CrossRef
Association between Attention Deficit Hyperactivity Disorder Medication and Depression: A 10-year Follow-up Self-controlled Case Study
Yunhye Oh, Yoo-Sook Joung, Jinseob Kim
Clinical Psychopharmacology and Neuroscience.2022; 20(2): 320. CrossRef
Association of Chronic Hepatitis B Infection and Antiviral Treatment With the Development of the Extrahepatic Malignancies: A Nationwide Cohort Study
Dong Hyeon Lee, Sung Won Chung, Jeong-Hoon Lee, Hwi Young Kim, Goh Eun Chung, Mi-Sook Kim, Bo Ram Yang, Joon Yeul Nam, Yun Bin Lee, Yoon Jun Kim, Jung-Hwan Yoon
Journal of Clinical Oncology.2022; 40(29): 3394. CrossRef
Cancer risk in the residents of a town near three industrial waste incinerators in Korea: a retrospective cohort study
Kyung-Hwa Choi, Hyungryul Lim, Sanghyuk Bae, Mina Ha, Ho-Jang Kwon, Mira Yoon, Seonmi Hong, Sang-Yong Eom, Yong-Dae Kim, Heon Kim
International Archives of Occupational and Environmental Health.2022; 95(9): 1829. CrossRef
Triglyceride-Glucose Index Is a Useful Marker for Predicting Future Cardiovascular Disease and Mortality in Young Korean Adults: A Nationwide Population-Based Cohort Study
Yun Kyung Cho, Kyung-do Han, Hwi Seung Kim, Chang Hee Jung, Joong-Yeol Park, Woo Je Lee
Journal of Lipid and Atherosclerosis.2022; 11(2): 178. CrossRef
Annual Trends in the Incidence and Prevalence of Alzheimer's Disease in South Korea: A Nationwide Cohort Study
Min Seok Baek, Han-Kyeol Kim, Kyungdo Han, Hyuk-Sung Kwon, Han Kyu Na, Chul Hyoung Lyoo, Hanna Cho
Frontiers in Neurology.2022;[Epub] CrossRef
Risk Factors of Incident Lung Cancer in Patients with Non-Cystic Fibrosis Bronchiectasis: A Korean Population-Based Study
Youlim Kim, Kyungdo Han, Juhwan Yoo, Hyung Koo Kang, Tai Sun Park, Dong Won Park, Ji Young Hong, Ji-Yong Moon, Sang-Heon Kim, Tae Hyung Kim, Kwang Ha Yoo, Jang Won Sohn, Ho Joo Yoon, Hayoung Choi, Hyun Lee
Cancers.2022; 14(11): 2604. CrossRef
Association Between Hypertension and Incident Infective Endocarditis
Gyu Bae Lee, Koh Eun Shin, Kyungdo Han, Ho-Sung Son, Jae-Seung Jung, Yang-Hyun Kim, Hee-Jung Kim
Hypertension.2022; 79(7): 1466. CrossRef
Risk of secondary nonhematologic malignancies after allogeneic stem cell transplantation: A nationwide case‐control cohort study
Sung‐Soo Park, Si‐Hyun Park, Seunghoon Han
International Journal of Cancer.2022; 151(7): 1024. CrossRef
Acute myocardial infarction risk in multiple sclerosis and neuromyelitis optica spectrum disorder: A nationwide cohort study in South Korea
Eun Bin Cho, Yohwan Yeo, Jin-Hyung Jung, Su-Min Jeong, Kyungdo Han, Jeong Hoon Yang, Dong Wook Shin, Ju-Hong Min
Multiple Sclerosis Journal.2022; 28(12): 1849. CrossRef
Nationwide population-based incidence of cancer among patients with HIV/AIDS in South Korea
Soon Ok Lee, Jeong Eun Lee, Shinwon Lee, Sun Hee Lee, Jin Suk Kang, Hyunjin Son, Hyungi Lee, Jinmi Kim
Scientific Reports.2022;[Epub] CrossRef
Association between migraine and risk of ocular motor cranial nerve palsy
Soolienah Rhiu, Kyungdo Han, Juhwan Yoo, Kyung-Ah Park, Sei Yeul Oh
Scientific Reports.2022;[Epub] CrossRef
Statin use and risk of progression to liver cirrhosis in chronic hepatitis B independent of conventional risk factors: A nationwide study
Byungyoon Yun, Sang Hoon Ahn, Jin‐Ha Yoon, Beom Kyung Kim
Hepatology Communications.2022; 6(9): 2455. CrossRef
Association Between Metabolic Syndrome and the Risk of Colorectal Cancer Diagnosed Before Age 50 Years According to Tumor Location
Eun Hyo Jin, Kyungdo Han, Dong Ho Lee, Cheol Min Shin, Joo Hyun Lim, Yoon Jin Choi, Kichul Yoon
Gastroenterology.2022; 163(3): 637. CrossRef
A positive faecal immunochemical test result and its association with the incidence of rheumatoid arthritis, systemic lupus erythematosus, and psoriatic arthritis: an analysis of one-million national colorectal cancer screening programme results
Choong-Kyun Noh, Eunyoung Lee, Bumhee Park, Sung Soo Ahn
BMC Medicine.2022;[Epub] CrossRef
Obesity Fact Sheet in Korea, 2021: Trends in Obesity Prevalence and Obesity-Related Comorbidity Incidence Stratified by Age from 2009 to 2019
Ye Seul Yang, Byoung-Duck Han, Kyungdo Han, Jin-Hyung Jung, Jang Won Son
Journal of Obesity & Metabolic Syndrome.2022; 31(2): 169. CrossRef
Venous Thromboembolism Risk in Asian Patients with Inflammatory Bowel Disease: A Population-Based Nationwide Inception Cohort Study
Su Young Kim, Yeon Seo Cho, Hyun-Soo Kim, Jung Kuk Lee, Hee Man Kim, Hong Jun Park, Hyunil Kim, Jihoon Kim, Dae Ryong Kang
Gut and Liver.2022; 16(4): 555. CrossRef
Impact of Wildfire Smoke Exposure on Health in Korea
Kihyun Lee, Sung-Soo Oh, Kyoung Sook Jeong, Yeon-Soon Ahn, Sei Jin Chang, Se Hwa Hong, Dae Ryong Kang, Sung-Kyung Kim, Sang-Baek Koh
Yonsei Medical Journal.2022; 63(8): 774. CrossRef
Risk for Behçet’s disease gauged via high-density lipoprotein cholesterol: a nationwide population-based study in Korea
Yeong Ho Kim, Hyun Jee Kim, Jin Woo Park, Kyung Do Han, Yong Gyu Park, Young Bok Lee, Ji Hyun Lee
Scientific Reports.2022;[Epub] CrossRef
Analysis of Mortality in Intracerebral Hemorrhage Patients with Hyperacute Ischemic Stroke Treated Using Thrombolytic Therapy: A Nationwide Population-based Cohort Study in South Korea
Hyun-Young Choi, Yongil Cho, Wonhee Kim, Yang-Ki Minn, Gu-Hyun Kang, Yong-Soo Jang, Yoonje Lee, Jae-Guk Kim, Jihoon Kim, Youngsuk Cho, Hyungoo Shin, Shinje Moon, Chiwon Ahn, Juncheol Lee, Dong-Geum Shin, Jae-Keun Park
Journal of Personalized Medicine.2022; 12(8): 1260. CrossRef
Institutional case volume and mortality after aortic and mitral valve replacement: a nationwide study in two Korean cohorts
Karam Nam, Eun Jin Jang, Jun Woo Jo, Jiwon You, Jung-Bin Park, Ho Geol Ryu
Journal of Cardiothoracic Surgery.2022;[Epub] CrossRef
Effect of metabolic dysfunction‐associated fatty liver disease on liver cancer risk in a population with chronic hepatitis B virus infection: A nationwide study
Byungyoon Yun, Sang Hoon Ahn, Juyeon Oh, Jin‐Ha Yoon, Beom Kyung Kim
Hepatology Research.2022; 52(12): 975. CrossRef
Non–Cystic Fibrosis Bronchiectasis Increases the Risk of Lung Cancer Independent of Smoking Status
Hayoung Choi, Hye Yun Park, Kyungdo Han, Juhwan Yoo, Sun Hye Shin, Bumhee Yang, Youlim Kim, Tai Sun Park, Dong Won Park, Ji-Yong Moon, Seung Won Ra, Sang-Heon Kim, Tae-Hyung Kim, Yeon-Mok Oh, Ho Joo Yoon, Jang Won Sohn, Hyun Lee
Annals of the American Thoracic Society.2022; 19(9): 1551. CrossRef
Real-World Prescription Patterns and Barriers Related to the Use of Sodium-Glucose Cotransporter 2 Inhibitors among Korean Patients with Type 2 Diabetes Mellitus and Cardiovascular Disease
Jong Ha Baek, Ye Seul Yang, Seung-Hyun Ko, Kyung Do Han, Jae Hyeon Kim, Min Kyong Moon, Jong Suk Park, Byung-Wan Lee, Tae Jung Oh, Suk Chon, Jong Han Choi, Kyu Yeon Hur
Diabetes & Metabolism Journal.2022; 46(5): 701. CrossRef
Editor's Choice – Effect of Physical Activity and Tobacco Use on Mortality and Morbidity in Patients with Peripheral Arterial Disease After Revascularisation: A Korean Nationwide Population Based Cohort Study
Seungwoo Cha, Sherry L. Grace, Kyungdo Han, Bongseong Kim, Nam-Jong Paik, Won-Seok Kim
European Journal of Vascular and Endovascular Surgery.2022; 64(4): 417. CrossRef
Augmented risk of ischemic stroke in hypertrophic cardiomyopathy patients without documented atrial fibrillation
You-Jung Choi, Bongseong Kim, Tae-Min Rhee, Hyun-Jung Lee, Heesun Lee, Jun-Bean Park, Seung-Pyo Lee, Kyung-Do Han, Yong-Jin Kim, Hyung-Kwan Kim
Scientific Reports.2022;[Epub] CrossRef
Depression in patients with inflammatory bowel disease is associated with increased risk of dementia and Parkinson’s disease: A nationwide, population-based study
Kookhwan Choi, Hyun Jung Lee, Kyungdo Han, Seong-Joon Koh, Jong Pil Im, Joo Sung Kim
Frontiers in Medicine.2022;[Epub] CrossRef
Individual socioeconomic status and risk of out‐of‐hospital cardiac arrest: A nationwide case–control analysis
Sun Young Lee, Jeong Ho Park, Young Ho Choi, Jungah Lee, Young Sun Ro, Ki Jeong Hong, Kyoung Jun Song, Sang Do Shin
Academic Emergency Medicine.2022; 29(12): 1438. CrossRef
Impact of nationwide hepatocellular carcinoma surveillance on the prognosis in patients with chronic liver disease
Won Sohn, Danbee Kang, Minwoong Kang, Eliseo Guallar, Juhee Cho, Yong-Han Paik
Clinical and Molecular Hepatology.2022; 28(4): 851. CrossRef
Population Prevalence, Cancer Risk, and Mortality Risk of Turner Syndrome in South Korean Women Based on National Health Insurance Service Data
Sung Eun Kim, Sang Hyun Park, Kyungdo Han, Won Kyoung Cho, Byung-Kyu Suh, Yong-Gyu Park
Yonsei Medical Journal.2022; 63(11): 991. CrossRef
Effects of Endocrine Therapy on Cardiovascular Diseases and Type 2 Diabetes Among Breast Cancer Survivors: The National Health Insurance Service Database of Korea
Ji‐Eun Kim, Jaesung Choi, JooYong Park, Wonshik Han, Daehee Kang, Ji‐Yeob Choi
Journal of the American Heart Association.2022;[Epub] CrossRef
Association between exercise and risk of cardiovascular diseases in patients with non-cystic fibrosis bronchiectasis
Hayoung Choi, Sang Hyuk Kim, Kyungdo Han, Tai Sun Park, Dong Won Park, Ji-Yong Moon, Sang-Heon Kim, Tae-Hyung Kim, Jang Won Sohn, Ho Joo Yoon, Hyun Lee
Respiratory Research.2022;[Epub] CrossRef
Development and Evaluation of Machine Learning-Based High-Cost Prediction Model Using Health Check-Up Data by the National Health Insurance Service of Korea
Yeongah Choi, Jiho An, Seiyoung Ryu, Jaekyeong Kim
International Journal of Environmental Research and Public Health.2022; 19(20): 13672. CrossRef
Comparing Non-Communicable Disease Risk Factors in Asian Migrants and Native Koreans among the Asian Population
Heng Piao, Jae Moon Yun, Aesun Shin, Belong Cho, Daehee Kang
Biomolecules & Therapeutics.2022; 30(6): 603. CrossRef
Chronic kidney disease as a risk factor for abdominal aortic aneurysm: a nationwide population-based study
Kang-woong Jun, Ju-hwan Yoo, Kyung-jai Ko, Hyung-jin Cho, Mi-hyeong Kim, Kyung-do Han, Jeong-kye Hwang
Annals of Surgical Treatment and Research.2022; 103(5): 297. CrossRef
Epidemiology and Management Trend of Renal Trauma: Results of a Nationwide Population-Based Study
Bum Sik Tae, Hoon Ah Jang, Jihyeong Yu, Kyung-Jin Oh, Kyung Hyun Moon, Jae Young Park
Journal of Korean Medical Science.2022;[Epub] CrossRef
Low-to-moderate atmospheric ozone levels are negatively correlated with hospital visits by asthma patients
Soyeon Lee, Minhyeok Lee
Medicine.2022; 101(45): e31737. CrossRef
Acute Pancreatitis Increases the Risk of Gastrointestinal Cancer in Type 2 Diabetic Patients: A Korean Nationwide Cohort Study
Jin Ho Choi, Woo Hyun Paik, Dong Kee Jang, Min Kyu Kim, Ji Kon Ryu, Yong-Tae Kim, Kyungdo Han, Sang Hyub Lee
Cancers.2022; 14(22): 5696. CrossRef
Fasting Glucose Variability and the Risk of Dementia in Individuals with Diabetes: A Nationwide Cohort Study
Da Young Lee, Jaeyoung Kim, Sanghyun Park, So Young Park, Ji Hee Yu, Ji A Seo, Nam Hoon Kim, Hye Jin Yoo, Sin Gon Kim, Kyung Mook Choi, Sei Hyun Baik, Kyungdo Han, Nan Hee Kim
Diabetes & Metabolism Journal.2022; 46(6): 923. CrossRef
The association between changes in hepatic steatosis and hepatic fibrosis with cardiovascular outcomes and mortality in patients with New-Onset type 2 Diabetes: A nationwide cohort study
Jiyun Park, Gyuri Kim, Bong-Sung Kim, Kyung-Do Han, So Yoon Kwon, So Hee Park, You-Bin Lee, Sang-Man Jin, Jae Hyeon Kim
Diabetes Research and Clinical Practice.2022; 194: 110191. CrossRef
Long-term outcomes of preterm infants in the first 6 years of life: a nationwide population-based study in Korea
Ju Hyun Jin, Sung Hee Lee, Tae Mi Youk, Shin Won Yoon
European Journal of Pediatrics.2022; 182(2): 641. CrossRef
Risk of malignancy in patients with psoriasis according to treatment modalities in Korea: a nationwide cohort study
Ji Youn Hong, Juhee Ahn, Sungho Won, Sung Min Kim, Young Ah Cho, Chang Yong Kim, Jae Young Sung, Da-Ae Yu, Yang Won Lee, Yong Beom Choe
Scientific Reports.2022;[Epub] CrossRef
Association between physical activity and risk of renal function decline and mortality in community-dwelling older adults: a nationwide population-based cohort study
Hyunsuk Kim, Mun Jung Ko, Chi-Yeon Lim, Eunjin Bae, Young Youl Hyun, Sungjin Chung, Soon Hyo Kwon, Jang-Hee Cho, Kyung Don Yoo, Woo Yeong Park, In O Sun, Byung Chul Yu, Gang-Jee Ko, Jae Won Yang, Won Min Hwang, Sang Heon Song, Sung Joon Shin, Yu Ah Hong
BMC Geriatrics.2022;[Epub] CrossRef
The associations between changes in hepatic steatosis and heart failure and mortality: a nationwide cohort study
Jiyun Park, Gyuri Kim, Hasung Kim, Jungkuk Lee, Sang-Man Jin, Jae Hyeon Kim
Cardiovascular Diabetology.2022;[Epub] CrossRef
Incidence of edentulism among older adults using the Korean National Health Insurance Service database, 2013-2018
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Risk of Neurodegenerative Diseases in Patients With Acromegaly
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Association between Body Mass Index and Risk of Coronavirus Disease 2019 (COVID-19): A Nationwide Case-control Study in South Korea
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Increased risk of cancer in patients with retinal vein occlusion: a 12-year nationwide cohort study
Min Seok Kim, Joon Hee Cho, Seong Jun Byun, Chang-Mo Oh, Kyu Hyung Park, Sang Jun Park
British Journal of Ophthalmology.2021; 105(12): 1705. CrossRef
Conditional relative survival and competing mortality in patients who underwent surgery for lung cancer: A nationwide cohort study
Jung Eun Yoo, Kyungdo Han, Dong Wook Shin, Sang Hyun Park, In Young Cho, Dong Woog Yoon, Jongho Cho, Kyu‐Won Jung
International Journal of Cancer.2021; 148(3): 626. CrossRef
Impact of Benign Prostatic Hyperplasia and/or Prostatitis on the Risk of Prostate Cancer in Korean Patients
Sung Han Kim, Whi-An Kwon, Jae Young Joung
The World Journal of Men's Health.2021; 39(2): 358. CrossRef
High prevalence of physical inactivity after heart valve surgery and its association with long-term mortality: A nationwide cohort study
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European Journal of Preventive Cardiology.2021; 28(7): 749. CrossRef
Risk of cancer incidence in patients with idiopathic pulmonary fibrosis: A nationwide cohort study
Hong Yeul Lee, Jinwoo Lee, Chang‐Hoon Lee, Kyungdo Han, Sun Mi Choi
Respirology.2021; 26(2): 180. CrossRef
Association of physical activity with all-cause and cardiovascular mortality in 7666 adults with hypertrophic cardiomyopathy (HCM): more physical activity is better
Soonil Kwon, Hyun-Jung Lee, Kyung-Do Han, Da Hye Kim, Seung-Pyo Lee, In-Chang Hwang, Yeonyee Yoon, Jun-Bean Park, Heesun Lee, Soongu Kwak, Seokhun Yang, Goo-Yeong Cho, Yong-Jin Kim, Hyung-Kwan Kim, Steve R Ommen
British Journal of Sports Medicine.2021; 55(18): 1034. CrossRef
Traditional medicine for the treatment of common cold in Korean adults: A nationwide population-based study
Hyungtae Kim, Jun-Yong Choi, Minna Hong, Hae Sun Suh
Integrative Medicine Research.2021; 10(1): 100458. CrossRef
Physical activity after ischemic stroke and its association with adverse outcomes: A nationwide population-based cohort study
Seong-Min Kang, Sun-Hyung Kim, Kyung-Do Han, Nam-Jong Paik, Won-Seok Kim
Topics in Stroke Rehabilitation.2021; 28(3): 170. CrossRef
Obesity and breast cancer risk for pre- and postmenopausal women among over 6 million Korean women
Jae Won Park, Kyungdo Han, Dong Wook Shin, Yohwan Yeo, Ji Won Chang, Jung Eun Yoo, Su-Min Jeong, Se-Kyung Lee, Jai Min Ryu, Yong-Moon Park
Breast Cancer Research and Treatment.2021; 185(2): 495. CrossRef
Association of Hypertension With the Risk and Severity of Epistaxis
Hayoung Byun, Jae Ho Chung, Seung Hwan Lee, Jiin Ryu, Changsun Kim, Jeong-Hun Shin
JAMA Otolaryngology–Head & Neck Surgery.2021; 147(1): 34. CrossRef
The risk of hip fractures in individuals over 50 years old with prediabetes and type 2 diabetes – A longitudinal nationwide population-based study
Ho Youn Park, Kyoungdo Han, Youngwoo Kim, Yoon Hwan Kim, Yoo Joon Sur
Bone.2021; 142: 115691. CrossRef
Increased atrial fibrillation risk in Parkinson’s disease: A nationwide population‐based study
Seokmoon Han, Inki Moon, Eue‐Keun Choi, Kyung‐Do Han, Hae‐Chan Cho, Seo‐Young Lee, Seokhun Yang, Soonil Kwon, You‐jung Choi, Hyun‐Jung Lee, Euijae Lee, So‐Ryung Lee, Seil Oh
Annals of Clinical and Translational Neurology.2021; 8(1): 238. CrossRef
Risk of Cancer Following the Use of N-Nitrosodimethylamine (NDMA) Contaminated Ranitidine Products: A Nationwide Cohort Study in South Korea
Hong Jin Yoon, Jie-Hyun Kim, Gi Hyeon Seo, Hyojin Park
Journal of Clinical Medicine.2021; 10(1): 153. CrossRef
The insulin resistance by triglyceride glucose index and risk for dementia: population-based study
Sangmo Hong, Kyungdo Han, Cheol-Young Park
Alzheimer's Research & Therapy.2021;[Epub] CrossRef
Ten-Year Relative Survival From the Diagnosis of Parkinson's Disease: A Nationwide Database Study
Han Gil Seo, Seong Jun Byun, Byung-Mo Oh, Sang Jun Park
Journal of the American Medical Directors Association.2021; 22(8): 1757. CrossRef
Short- and long-term exposure to air pollution and lack of sunlight are associated with an increased risk of depression: A nested case-control study using meteorological data and national sample cohort data
So Young Kim, Minji Bang, Jee Hye Wee, Chanyang Min, Dae Myoung Yoo, Sang-Min Han, Seungdo Kim, Hyo Geun Choi
Science of The Total Environment.2021; 757: 143960. CrossRef
Associations between metabolic syndrome and type of dementia: analysis based on the National Health Insurance Service database of Gangwon province in South Korea
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Diabetology & Metabolic Syndrome.2021;[Epub] CrossRef
Repeatedly elevated γ-glutamyltransferase levels are associated with an increased incidence of digestive cancers: A population-based cohort study
Chang-Hoon Lee, Kyungdo Han, Da Hye Kim, Min-Sun Kwak
World Journal of Gastroenterology.2021; 27(2): 176. CrossRef
Incidence and prevalence of systemic lupus erythematosus among Korean women in childbearing years: A nationwide population-based study
Min Kyung Chung, Jin Su Park, Hyunsun Lim, Chan Hee Lee, Jisoo Lee
Lupus.2021; 30(4): 674. CrossRef
Effect of institutional case volume on mid-term mortality after coronary artery bypass grafting surgery
Seohee Lee, Eun Jin Jang, Junwoo Jo, Dongyeon Jang, Bo Rim Kim, Ho Geol Ryu
General Thoracic and Cardiovascular Surgery.2021; 69(9): 1275. CrossRef
Rheumatoid arthritis in low‐level toluene‐exposed workers based on nationwide medical surveillance data in Korea
Young‐Sun Min, Sungho Lee, Mingi Kim, Yeon‐Soon Ahn
American Journal of Industrial Medicine.2021; 64(4): 245. CrossRef
Status of Diabetic Neuropathy in Korea: A National Health Insurance Service-National Sample Cohort Analysis (2006 to 2015)
Seong-Su Moon, Chong Hwa Kim, Seon Mee Kang, Eun Sook Kim, Tae Jung Oh, Jae-Seung Yun, Ho Chan Cho, Dae Jung Kim, Tae Sun Park
Diabetes & Metabolism Journal.2021; 45(1): 115. CrossRef
Risk factors associated with failure of total ankle arthroplasty: a nationwide cohort study
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Scientific Reports.2021;[Epub] CrossRef
Impact of body mass index on development of nontuberculous mycobacterial pulmonary disease
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European Respiratory Journal.2021; 57(2): 2000454. CrossRef
Survival in untreated hepatocellular carcinoma: A national cohort study
Young Ae Kim, Danbee Kang, Hyeyoung Moon, Donghyun Sinn, Minwoong Kang, Sang Myung Woo, Yoon Jung Chang, Boram Park, Sun-Young Kong, Eliseo Guallar, Soo-Yong Shin, Geunyeon Gwak, Joung Hwan Back, Eun Sook Lee, Juhee Cho, Gianfranco D. Alpini
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Early and Two-year Outcomes after Sutureless and Conventional Aortic Valve Replacement: a Nationwide Population-based Study
Jae Woong Choi, Ho Jin Kim, Joon Bum Kim, Sak Lee, Cheong Lim, Byung Chul Chang, Youshin Suh, Na Rae Lee, Ho Young Hwang
Journal of Korean Medical Science.2021;[Epub] CrossRef
Assessment of Trends in the Incidence Rates of Central Retinal Artery Occlusion in Korea From 2002 to 2015
Jongshin Kim, Seong Jun Byun, Se Joon Woo, Kyu Hyung Park, Sang Jun Park
JAMA Ophthalmology.2021; 139(4): 399. CrossRef
The incidence of myocardial infarction and stroke in head and neck cancer patients
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Long-term impacts of appendectomy associated with increased incidence of inflammatory bowel disease, infection, and colorectal cancer
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International Journal of Colorectal Disease.2021; 36(8): 1643. CrossRef
Severe hypoglycemia and the risk of end stage renal disease in type 2 diabetes
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Proteinuria Is Associated with the Development of Crohn’s Disease: A Nationwide Population-Based Study
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Journal of Clinical Medicine.2021; 10(4): 799. CrossRef
Lifestyle is associated with atrial fibrillation development in patients with type 2 diabetes mellitus
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Determining the association between repeatedly elevated serum gamma‐glutamyltransferase levels and risk of respiratory cancer: A nationwide population‐based cohort study
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Cancer Medicine.2021; 10(4): 1366. CrossRef
The Repeatedly Elevated Fatty Liver Index Is Associated With Increased Mortality: A Population-Based Cohort Study
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Frontiers in Endocrinology.2021;[Epub] CrossRef
A nationwide population-based study in South Korea on a relationship between height and anosmia
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Scientific Reports.2021;[Epub] CrossRef
Effect of healthcare benefits on short‐term adherence of positive airway pressure therapy
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Comparative Surgical Outcomes of Prosthetic and Native Valve Endocarditis
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Korean Circulation Journal.2021; 51(6): 504. CrossRef
Analysis of application of dental sedation in attention deficit hyperactivity disorder (ADHD) patients using the Korean National Health Insurance data
Seong In Chi, Hyuk Kim, Kwang-Suk Seo
Journal of Dental Anesthesia and Pain Medicine.2021; 21(2): 99. CrossRef
Deep Spinal Infection after Outpatient Epidural Injections for Pain: A Retrospective Sample Cohort Study Using a Claims Database in South Korea
Chang-Soon Lee, Young Jae Park, Jee Youn Moon, Yong-Chul Kim
Anesthesiology.2021; 134(6): 925. CrossRef
Obesity, metabolic health, and urological disorders in adults: a nationwide population-based study
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Pre-transplant Dementia is Associated with Poor Survival After Hematopoietic Stem Cell Transplantation: A Nationwide Cohort Study with Propensity Score Matched Control
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Risks and Prognoses of Alzheimer's Disease and Vascular Dementia in Patients With Insomnia: A Nationwide Population-Based Study
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The Association Between Second-Line Oral Antihyperglycemic Medication on Types of Dementia in Type 2 Diabetes: A Nationwide Real-World Longitudinal Study
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Effect of Short-Term Exposure to Fine Particulate Matter and Temperature on Acute Myocardial Infarction in Korea
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International Journal of Environmental Research and Public Health.2021; 18(9): 4822. CrossRef
Incident Parkinson’s disease in kidney transplantation recipients: a nationwide population-based cohort study in Korea
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Risk of COVID-19 and major adverse clinical outcomes among people with disabilities in South Korea
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Use of Proton Pump Inhibitors vs Histamine 2 Receptor Antagonists for the Risk of Gastric Cancer: Population-Based Cohort Study
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American Journal of Gastroenterology.2021; 116(6): 1211. CrossRef
Risk of upper gastrointestinal bleeding in patients on oral anticoagulant and proton pump inhibitor co-therapy
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Long-term mortality due to infection associated with elevated liver enzymes: a population-based cohort study
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Newly diagnosed diabetes has high risk for cardiovascular outcome in ischemic stroke patients
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Tooth loss is associated with an increased risk of hypertension: A nationwide population-based cohort study
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Anemia May Increase the Overall Risk of Cancer: Findings from a Cohort Study with a 12-Year Follow-up Period in South Korea
Tak Kyu Oh, In-Ae Song
Cancer Epidemiology, Biomarkers & Prevention.2021; 30(7): 1440. CrossRef
Association of mortality with drug-coated devices in femoropopliteal artery based on the nationwide data
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Annals of Surgical Treatment and Research.2021; 101(1): 20. CrossRef
Seasonal variation of patulous Eustachian tube diagnoses using climatic and national health insurance data
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The Journal of Laryngology & Otology.2021; 135(8): 695. CrossRef
Clinical Study Using Healthcare Claims Database
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Journal of Rheumatic Diseases.2021; 28(3): 119. CrossRef
History of anemia and long-term mortality due to infection: a cohort study with 12 years follow-up in South Korea
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BMC Infectious Diseases.2021;[Epub] CrossRef
Trends of age‐related non‐communicable diseases in people living with HIV and comparison with uninfected controls: A nationwide population‐based study in South Korea
Jung Ho Kim, Juhwan Noh, Woojin Kim, Hye Seong, Jun Hyoung Kim, Woon Ji Lee, YaeJee Baek, JongHoon Hyun, Yujin Sohn, Yunsuk Cho, Moo Hyun Kim, SangMin Ahn, Yongseop Lee, Jin Young Ahn, Su Jin Jeong, Nam Su Ku, Joon‐Sup Yeom, Changsoo Kim, Jun Yong Choi
HIV Medicine.2021; 22(9): 824. CrossRef
Risk of Heart Disease after Cholecystectomy: A Nationwide Population-Based Cohort Study in South Korea
Yoo Jin Kim, Young Soo Park, Cheol Min Shin, Kyungdo Han, Sang Hyun Park, Hyuk Yoon, Nayoung Kim, Dong Ho Lee
Journal of Clinical Medicine.2021; 10(15): 3253. CrossRef
Dose-Dependent Effect of Smoking on Risk of Diabetes Remains after Smoking Cessation: A Nationwide Population-Based Cohort Study in Korea
Se Eun Park, Mi Hae Seo, Jung-Hwan Cho, Hyemi Kwon, Yang-Hyun Kim, Kyung-Do Han, Jin-Hyung Jung, Yong-Gyu Park, Eun-Jung Rhee, Won-Young Lee
Diabetes & Metabolism Journal.2021; 45(4): 539. CrossRef
Automatic Classification of Thyroid Findings Using Static and Contextualized Ensemble Natural Language Processing Systems: Development Study
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JMIR Medical Informatics.2021; 9(9): e30223. CrossRef
Effect of Sedatives on In-hospital and Long-term Mortality of Critically Ill Patients Requiring Extended Mechanical Ventilation for ≥ 48 Hours
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Prior antiviral treatment and mortality among patients with hepatitis C virus-related hepatocellular carcinoma: A national cohort study
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Relationship between total cholesterol level and tuberculosis risk in a nationwide longitudinal cohort
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Scientific Reports.2021;[Epub] CrossRef
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Medicine.2021; 100(30): e26670. CrossRef
The Association between Peri-Transplant RBC Transfusion and Graft Failure after Kidney Transplantation: A Nationwide Cohort Study
Kyungho Lee, Seohee Lee, Eun Jin Jang, Ga Hee Kim, Seokha Yoo, Minkyoo Lee, Hye Ryoun Jang, Ho Geol Ryu
Journal of Clinical Medicine.2021; 10(16): 3750. CrossRef
Empathy With Patients and Post-Traumatic Stress Response in Verbally Abused Healthcare Workers
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Psychiatry Investigation.2021; 18(8): 770. CrossRef
Smoking cessation, but not reduction, reduces cardiovascular disease incidence
Su-Min Jeong, Keun Hye Jeon, Dong Wook Shin, Kyungdo Han, Dahye Kim, Sang Hyun Park, Mi Hee Cho, Cheol Min Lee, Ki-Woong Nam, Seung Pyo Lee
European Heart Journal.2021; 42(40): 4141. CrossRef
Does Exposure of Lead and Cadmium Affect the Endometriosis?
Min-Gi Kim, Young-Sun Min, Yeon-Soon Ahn
International Journal of Environmental Research and Public Health.2021; 18(17): 9077. CrossRef
Association of Periodontal Disease with the Occurrence of Unruptured Cerebral Aneurysm among Adults in Korea: A Nationwide Population-Based Cohort Study
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Medicina.2021; 57(9): 910. CrossRef
Synergistic harmful interaction between sustained physical inactivity and hypertension/diabetes mellitus on the risk of all-cause mortality: a retrospective observational cohort study
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Being Underweight Increases the Risk of Non-Cystic Fibrosis Bronchiectasis in the Young Population: A Nationwide Population-Based Study
Bumhee Yang, Kyungdo Han, Sang Hyuk Kim, Dong-Hwa Lee, Sang Hyun Park, Jung Eun Yoo, Dong Wook Shin, Hayoung Choi, Hyun Lee
Nutrients.2021; 13(9): 3206. CrossRef
Particular matter influences the incidence of acute otitis media in children
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Changes in the Prosthesis Types Used for Aortic Valve Replacement after the Introduction of Sutureless and Rapid Deployment Valves in Korea: A Nationwide Population-Based Cohort Study
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Journal of Chest Surgery.2021; 54(5): 369. CrossRef
Association between haemorrhagic fever with renal syndrome and cancers
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International Journal of Infectious Diseases.2021; 113: 127. CrossRef
Blood Pressure and Cardiovascular Disease in Older Patients With Diabetes: Retrospective Cohort Study
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Journal of the American Heart Association.2021;[Epub] CrossRef
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Myung-Sun Song, Yeon joo Choi, Hyunjin Kim, Myung Ji Nam, Chung-woo Lee, Kyungdo Han, Jin-Hyung Jung, Yong-Gyu Park, Do-Hoon Kim, Joo-Hyun Park
BMC Geriatrics.2021;[Epub] CrossRef
Effects of menopausal hormone therapy on cardiovascular diseases and type 2 diabetes in middle-aged postmenopausal women: analysis of the Korea National Health Insurance Service Database
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Menopause.2021; 28(11): 1225. CrossRef
Epidemiology of Achilles Tendon Rupture in South Korea: Claims Data of the National Health Insurance Service from 2009 to 2017
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Clinics in Orthopedic Surgery.2021; 13(4): 539. CrossRef
Comparison of risk profiles for new-onset atrial fibrillation between patients aged <60 and ≥60 years
In-Soo Kim, Yeon-Jik Choi, Eui-Young Choi, Pil-Ki Min, Young Won Yoon, Byoung Kwon Lee, Bum-Kee Hong, Se-Joong Rim, Hyuck Moon Kwon, Jong-Youn Kim, Luigi Sciarra
PLOS ONE.2021; 16(11): e0258770. CrossRef
Comparison of Risk of Pneumonia Caused by Fluticasone Propionate versus Budesonide in Chronic Obstructive Pulmonary Disease: A Nationwide Retrospective Cohort Study
Jae-Hwa Choi, Keun-Bae Jeong, You Hyun Park, Iseul Yu, Seok Jeong Lee, Myoung Kyu Lee, Sang-Ha Kim, Won-Yeon Lee, Suk Joong Yong, Ji-Ho Lee
International Journal of Chronic Obstructive Pulmonary Disease.2021; Volume 16: 3229. CrossRef
Clinical Impact of Hormone Replacement Therapy on Atrial Fibrillation in Postmenopausal Women: A Nationwide Cohort Study
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Journal of Clinical Medicine.2021; 10(23): 5497. CrossRef
Rheumatoid Arthritis in Silica-Exposed Workers
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International Journal of Environmental Research and Public Health.2021; 18(23): 12776. CrossRef
Changes in metabolic syndrome and risk of psoriasis: a nationwide population-based study
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Fasting Glucose Variability as a Risk Indicator for End-Stage Kidney Disease in Patients with Diabetes: A Nationwide Population-Based Study
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Journal of Clinical Medicine.2021; 10(24): 5948. CrossRef
Female Reproductive Factors and Risk of Bronchiectasis: A Nationwide Population-Based Longitudinal Study
Bumhee Yang, Dong-Hwa Lee, Kyungdo Han, Hayoung Choi, Hyung Koo Kang, Dong Wook Shin, Hyun Lee
SSRN Electronic Journal .2021;[Epub] CrossRef
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American Journal of Kidney Diseases.2020; 76(2): 224. CrossRef
Gamma-glutamyl transferase variability can predict the development of end-stage of renal disease: a nationwide population-based study
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Association of Tooth Loss with New-Onset Parkinson’s Disease: A Nationwide Population-Based Cohort Study
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Physical performance and chronic kidney disease development in elderly adults: results from a nationwide cohort study
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Aging.2020; 12(17): 17393. CrossRef
Association Between Income Disparities and Risk of Chronic Kidney Disease
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Mayo Clinic Proceedings.2020; 95(2): 231. CrossRef
Pre-transplant depression decreased overall survival of patients receiving allogeneic hematopoietic stem cell transplantation: a nationwide cohort study
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Scientific Reports.2020;[Epub] CrossRef
Label Adherence of Direct Oral Anticoagulants Dosing and Clinical Outcomes in Patients With Atrial Fibrillation
Hee Tae Yu, Pil‐Sung Yang, Eunsun Jang, Tae‐Hoon Kim, Jae‐Sun Uhm, Jong‐Youn Kim, Hui‐Nam Pak, Moon‐Hyoung Lee, Gregory Y. H. Lip, Boyoung Joung
Journal of the American Heart Association.2020;[Epub] CrossRef
Associations among Obesity Degree, Glycemic Status, and Risk of Heart Failure in 9,720,220 Korean Adults
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Diabetes & Metabolism Journal.2020; 44(4): 592. CrossRef
Obesity Fact Sheet in Korea, 2019: Prevalence of Obesity and Abdominal Obesity from 2009 to 2018 and Social Factors
Ga Eun Nam, Yang-Hyun Kim, Kyungdo Han, Jin-Hyung Jung, Eun-Jung Rhee, Seong-Su Lee, Dae Jung Kim, Kwan-Woo Lee, Won-Young Lee
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Safety of acupuncture during pregnancy: a retrospective cohort study in Korea
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BJOG: An International Journal of Obstetrics & Gynaecology.2020; 127(1): 79. CrossRef
Bell’s palsy and obesity, alcohol consumption and smoking: A nested case-control study using a national health screening cohort
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Scientific Reports.2020;[Epub] CrossRef
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Da Young Lee, Kyungdo Han, Sanghyun Park, Ji Hee Yu, Ji A. Seo, Nam Hoon Kim, Hye Jin Yoo, Sin Gon Kim, Kyung Mook Choi, Sei Hyun Baik, Yong Gyu Park, Nan Hee Kim
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Increased Cardiovascular Risk and All-cause Death in Patients with Behçet Disease: A Korean Nationwide Population-based Dynamic Cohort Study
Hyo-Suk Ahn, Dongjae Lee, Soo Young Lee, Yeong Ho Kim, Ji Hyun Lee, Dong Soo Yu, Kyung-Do Han, Yong Gyu Park, Young Bok Lee
The Journal of Rheumatology.2020; 47(6): 903. CrossRef
Gamma-Glutamyl Transferase Variability and Risk of Dementia in Diabetes Mellitus: A Nationwide Population-Based Study
So-hyeon Hong, Kyungdo Han, Sanghyun Park, Seon Mee Kim, Nan Hee Kim, Kyung Mook Choi, Sei Hyun Baik, Yong Gyu Park, Hye Jin Yoo
The Journal of Clinical Endocrinology & Metabolism.2020; 105(3): e119. CrossRef
Outcomes in relation to antithrombotic therapy among patients with atrial fibrillation after percutaneous coronary intervention
Jiesuck Park, Eue-Keun Choi, Kyung-Do Han, Bongseong Kim, You-Jung Choi, So-Ryoung Lee, Jeehoon Kang, Myung-Jin Cha, Kyung Woo Park, Seil Oh, Gregory Y. H. Lip, Chun Chieh Yeh
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Smoking and Alcohol Consumption Are Associated With the Increased Risk of Peritonsillar Abscess
So Young Kim, Hyoseob Lim, Hyo Geun Choi
The Laryngoscope.2020; 130(12): 2833. CrossRef
The Population Prevalence, Associations of Congenital Heart Defect and Mortality Risk for Down’s Syndrome in South Korea Based on National Health Insurance Service (NHIS) Data

Won Kyoung Cho, Na Young Lee, Kyungdo Han, Byung-Kyu Suh, Yong-Gyu Park
Clinical Epidemiology.2020; Volume 12: 519. CrossRef
Prognostic value of long-term gamma-glutamyl transferase variability in individuals with diabetes: a nationwide population-based study
Da Young Lee, Kyungdo Han, Ji Hee Yu, Sanghyun Park, Ji A Seo, Nam Hoon Kim, Hye Jin Yoo, Sin Gon Kim, Seon Mee Kim, Kyung Mook Choi, Sei Hyun Baik, Yong Gyu Park, Nan Hee Kim
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Trends and risk factors of elderly-onset Crohn’s disease: A nationwide cohort study
Jung Min Moon, Eun Ae Kang, Kyungdo Han, Seung Wook Hong, Hosim Soh, Seona Park, Jooyoung Lee, Hyun Jung Lee, Jong Pil Im, Joo Sung Kim
World Journal of Gastroenterology.2020; 26(4): 404. CrossRef
Improved oral hygiene is associated with decreased risk of new-onset diabetes: a nationwide population-based cohort study
Yoonkyung Chang, Ji Sung Lee, Ki-Jung Lee, Ho Geol Woo, Tae-Jin Song
Diabetologia.2020; 63(5): 924. CrossRef
Development of stroke identification algorithm for claims data using the multicenter stroke registry database
Jun Yup Kim, Keon-Joo Lee, Jihoon Kang, Beom Joon Kim, Moon-Ku Han, Seong-Eun Kim, Heeyoung Lee, Jong-Moo Park, Kyusik Kang, Soo Joo Lee, Jae Guk Kim, Jae-Kwan Cha, Dae-Hyun Kim, Tai Hwan Park, Moo-Seok Park, Sang-Soon Park, Kyung Bok Lee, Hong-Kyun Park,
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Cardiovascular Research Using the Korean National Health Information Database
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Korean Circulation Journal.2020; 50(9): 754. CrossRef
Impact of the timing of Helicobacter pylori eradication on the risk of development of metachronous lesions after treatment of early gastric cancer: a population-based cohort study
Hyun Ju Kim, Yun Jin Kim, Seung In Seo, Woon Geon Shin, Chan Hyuk Park
Gastrointestinal Endoscopy.2020; 92(3): 613. CrossRef
Bodyweight fluctuation is associated with increased risk of incident atrial fibrillation
Hyun-Jung Lee, Eue-Keun Choi, Kyung-Do Han, Euijae Lee, Inki Moon, So-Ryoung Lee, Myung-Jin Cha, Seil Oh, Gregory Y.H. Lip
Heart Rhythm.2020; 17(3): 365. CrossRef
Longitudinal Study of Diabetic Differences between International Migrants and Natives among the Asian Population
Heng Piao, Jae Moon Yun, Aesun Shin, Belong Cho
Biomolecules & Therapeutics.2020; 28(1): 110. CrossRef
Early detection of influenza outbreak using time derivative of incidence
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EPJ Data Science.2020;[Epub] CrossRef
A prediction model of low back pain risk: a population based cohort study in Korea
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The Korean Journal of Pain.2020; 33(2): 153. CrossRef
The impact of PM2.5 on acute otitis media in children (aged 0–3): A time series study
Jongmin Oh, Seulbi Lee, Min-ho Kim, Youngrin Kwag, Hae Soon Kim, Soontae Kim, Shinhee Ye, Eunhee Ha
Environment International.2020; 145: 106133. CrossRef
Serum gamma-glutamyltransferase activity and Parkinson’s disease risk in men and women
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Scientific Reports.2020;[Epub] CrossRef
Association between institutional case volume and mortality following thoracic aorta replacement: a nationwide Korean cohort study
Karam Nam, Eun Jin Jang, Jun Woo Jo, Jae Woong Choi, Minkyoo Lee, Ho Geol Ryu
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Underutilization of Hospital-based Cardiac Rehabilitation after Acute Myocardial Infarction in Korea
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Infection, antibiotic exposure and development of atopic dermatitis: A nationwide case–control study
Chong Won Choi, Bo Ram Yang, Dong In Suh, Mi‐Sook Kim, Jungyoon Ohn, Jong Soo Hong, Joongyub Lee, Kyu Han Kim
The Journal of Dermatology.2020; 47(7): 707. CrossRef
Effect of the variability of blood pressure, glucose level, total cholesterol level, and body mass index on the risk of atrial fibrillation in a healthy population
So-Ryoung Lee, Eue-Keun Choi, Kyung-Do Han, Seung-Hwan Lee, Seil Oh
Heart Rhythm.2020; 17(1): 12. CrossRef
Impact of Mitral Valve Repair Case Volume on Postoperative Mortality　― A Nationwide Korean Cohort Study ―
Karam Nam, Eun Jin Jang, Jun Woo Jo, Jae Woong Choi, Jun Gi Jo, Jaehun Lee, Ho Geol Ryu
Circulation Journal.2020; 84(9): 1493. CrossRef
The Clinical Impact of Body Mass Index on Breast Cancer in Korea: A Nationwide Population-Based Cohort Study
Jae Hwan Jeong, Hak Min Lee, Hai Young Son, Ilkyun Lee
Journal of Breast Disease.2020; 8(1): 51. CrossRef
Improved oral hygiene care is associated with decreased risk of occurrence for atrial fibrillation and heart failure: A nationwide population-based cohort study
Yoonkyung Chang, Ho Geol Woo, Jin Park, Ji Sung Lee, Tae-Jin Song
European Journal of Preventive Cardiology.2020; 27(17): 1835. CrossRef
Increased Mortality Burden in Young Asian Subjects with Dysglycemia and Comorbidities
Eun-Jung Rhee, Inha Jung, Hyemi Kwon, Se Eun Park, Yang-Hyun Kim, Kyung-Do Han, Yong-Gyu Park, Won-Young Lee
Journal of Clinical Medicine.2020; 9(4): 1042. CrossRef
Fasting Plasma Glucose Variability and Gastric Cancer Risk in Individuals Without Diabetes Mellitus: A Nationwide Population-Based Cohort Study
So-hyeon Hong, Eunjin Noh, Jinsil Kim, Soon Young Hwang, Jun A. Kim, You-Bin Lee, Eun Roh, Kyung Mook Choi, Sei Hyun Baik, Geum Joon Cho, Hye Jin Yoo
Clinical and Translational Gastroenterology.2020; 11(9): e00221. CrossRef
Use of Gadoxetic Acid–enhanced Liver MRI and Mortality in More than 30 000 Patients with Hepatocellular Carcinoma: A Nationwide Analysis
Tae Wook Kang, Sun-Young Kong, Danbee Kang, Min Woong Kang, Young Kon Kim, Seong Hyun Kim, Dong Hyun Sinn, Young Ae Kim, Kui Son Choi, Eun Sook Lee, Sang Myung Woo, Joung Hwan Back, Eliseo Guallar, Juhee Cho
Radiology.2020; 295(1): 114. CrossRef
The association between sialolithiasis and smoking, alcohol drinking and obesity in Korea: a nested case-control study
Young Ju Jin, Young Eun Han, Hyo Geun Choi
BMC Public Health.2020;[Epub] CrossRef
Outcomes for Inappropriate Renal Dose Adjustment of Dipeptidyl Peptidase-4 Inhibitors in Patients With Type 2 Diabetes Mellitus: Population-Based Study
Sangmo Hong, Kyungdo Han, Cheol-Young Park
Mayo Clinic Proceedings.2020; 95(1): 101. CrossRef
Impact of Mean and Variability of High‐Density Lipoprotein‐Cholesterol on the Risk of Myocardial Infarction, Stroke, and Mortality in the General Population
Byung‐Hun Han, Kyungdo Han, Kun‐Ho Yoon, Mee Kyoung Kim, Seung‐Hwan Lee
Journal of the American Heart Association.2020;[Epub] CrossRef
Underweight Increases the Risk of End-Stage Renal Diseases for Type 2 Diabetes in Korean Population: Data From the National Health Insurance Service Health Checkups 2009–2017
Yang-Hyun Kim, Jun Goo Kang, Seong Jin Lee, Kyung-do Han, Sung-Hee Ihm, Kyung-Hwan Cho, Yong-Gyu Park
Diabetes Care.2020; 43(5): 1118. CrossRef
Pneumonia risk and its associated factors in Parkinson's disease: A National Database Study
Jun Hee Won, Seong Jun Byun, Byung-Mo Oh, Han-Joon Kim, Sang Jun Park, Han Gil Seo
Journal of the Neurological Sciences.2020; 415: 116949. CrossRef
The Association with rhegmatogenous retinal detachment and paediatric atopic dermatitis: a 12-year Nationwide Cohort Study
M. Choi, S. J. Byun, D. H. Lee, K. H. Kim, K. H. Park, S. J. Park
Eye.2020; 34(10): 1909. CrossRef
Peripartum Blood Transfusions are Associated with Increased Risk of Cancer: A National Retrospective Cohort Study

Geum Joon Cho, Michael S Oh, Min-Jeong Oh, Keon Vin Park, Sung Won Han, Young Kwang Chae
Clinical Epidemiology.2020; Volume 12: 659. CrossRef
The Burden of Cervical Cancer in Korea: A Population-Based Study
Jinhee Kim, Donghwan Lee, Kyung-Bok Son, SeungJin Bae
International Journal of Environmental Research and Public Health.2020; 17(17): 6308. CrossRef
Temporal trends of catheter ablation for patients with atrial fibrillation: A Korean nationwide population‐based study
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Journal of Cardiovascular Electrophysiology.2020; 31(10): 2616. CrossRef
Trend of prevalence and incidence of systemic lupus erythematosus in South Korea, 2005 to 2015: a nationwide population-based study
Eun Hui Bae, Sang Yeob Lim, Kyung-Do Han, Jin-Hyung Jung, Hong Sang Choi, Ha Yeon Kim, Chang Seong Kim, Seong Kwon Ma, Soo Wan Kim
The Korean Journal of Internal Medicine.2020; 35(3): 652. CrossRef
Achievement of the low-density lipoprotein cholesterol goal among patients with dyslipidemia in South Korea
Siin Kim, Sola Han, Pratik P. Rane, Yi Qian, Zhongyun Zhao, Hae Sun Suh, Luigina Guasti
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Oral health and gastrointestinal cancer: A nationwide cohort study
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Journal of Clinical Periodontology.2020; 47(7): 796. CrossRef
Site-specific cancer risk in patients with type 2 diabetes: a nationwide population-based cohort study in Korea
Suk Kyeong Kim, Ju-Young Jang, Dong-Lim Kim, Young A Rhyu, Suh Eun Lee, Seung-Hyun Ko, Kyungdo Han, Kee-Ho Song
The Korean Journal of Internal Medicine.2020; 35(3): 641. CrossRef
Data Configuration and Publication Trends for the Korean National Health Insurance and Health Insurance Review & Assessment Database
Hae Kyung Kim, Sun Ok Song, Junghyun Noh, In-Kyung Jeong, Byung-Wan Lee
Diabetes & Metabolism Journal.2020; 44(5): 671. CrossRef
Metformin and Gastrointestinal Cancer Development in Newly Diagnosed Type 2 Diabetes: A Population-Based Study in Korea
Ji Hong You, Sun Ok Song, Min Jin Kang, Yoon Young Cho, Sun Wook Kim, Sung Hwan Suh, Sujin Lee, Yong-ho Lee, Byung-Wan Lee
Clinical and Translational Gastroenterology.2020; 11(11): e00254. CrossRef
Machine learning prediction for mortality of patients diagnosed with COVID-19: a nationwide Korean cohort study
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The association between hospital case volume and in-hospital and one-year mortality after hip fracture surgery
Seokha Yoo, Eun Jin Jang, Junwoo Jo, Jun Gi Jo, Seungpyo Nam, Hansol Kim, Hannah Lee, Ho Geol Ryu
The Bone & Joint Journal.2020; 102-B(10): 1384. CrossRef
Association between physical activity and conversion from mild cognitive impairment to dementia
Yeo Jin Kim, Kyung-Do Han, Min Seok Baek, Hanna Cho, Eun Joo Lee, Chul Hyoung Lyoo
Alzheimer's Research & Therapy.2020;[Epub] CrossRef
Clinical Outcomes of COVID-19 Patients with Type 2 Diabetes: A Population-Based Study in Korea
Ji Hong You, Sang Ah Lee, Sung-Youn Chun, Sun Ok Song, Byung-Wan Lee, Dae Jung Kim, Edward J. Boyko
Endocrinology and Metabolism.2020; 35(4): 901. CrossRef
Does Diabetes Increase the Risk of Contracting COVID-19? A Population-Based Study in Korea
Sung-Youn Chun, Dong Wook Kim, Sang Ah Lee, Su Jung Lee, Jung Hyun Chang, Yoon Jung Choi, Seong Woo Kim, Sun Ok Song
Diabetes & Metabolism Journal.2020; 44(6): 897. CrossRef
The triglyceride glucose index is a simple and low-cost marker associated with atherosclerotic cardiovascular disease: a population-based study
Sangmo Hong, Kyungdo Han, Cheol-Young Park
BMC Medicine.2020;[Epub] CrossRef
The durability and effectiveness of sensor-augmented insulin pump therapy in pediatric and young adult patients with type 1 diabetes
Yun Jeong Lee, Young Ah Lee, Jae Hyun Kim, Hye Rim Chung, Min Jeong Gu, Ji Young Kim, Choong Ho Shin
Annals of Pediatric Endocrinology & Metabolism.2020; 25(4): 248. CrossRef
Impact of comorbid asthma on severity of coronavirus disease (COVID-19)
Sang Chul Lee, Kang Ju Son, Chang Hoon Han, Ji Ye Jung, Seon Cheol Park
Scientific Reports.2020;[Epub] CrossRef
Big Data in Ophthalmology
Ching-Yu Cheng, Zhi Da Soh, Shivani Majithia, Sahil Thakur, Tyler Hyungtaek Rim, Yih Chung Tham, Tien Yin Wong
Asia-Pacific Journal of Ophthalmology.2020; 9(4): 291. CrossRef
Maintenance of body weight is an important determinant for the risk of ischemic stroke: A nationwide population-based cohort study
Jung-Hwan Cho, Eun-Jung Rhee, Se Eun Park, Hyemi Kwon, Jin-Hyung Jung, Kyung-Do Han, Yong-Gyu Park, Soon-Jib Yoo, Yang-Hyun Kim, Won-Young Lee, Sabine Rohrmann
PLOS ONE.2019; 14(1): e0210153. CrossRef
Effect of Institutional Case Volume on In-Hospital and Long-Term Mortality in Critically Ill Patients Requiring Mechanical Ventilation for 48 Hours or More
Hannah Lee, Seongmi Choi, Eun Jin Jang, Juhee Lee, Dalho Kim, Seokha Yoo, Seung Young Oh, Ho Geol Ryu
Journal of Korean Medical Science.2019;[Epub] CrossRef
Impact of the 2015 Middle East Respiratory Syndrome Outbreak on Emergency Care Utilization and Mortality in South Korea
Sun Young Lee, Young-Ho Khang, Hwa-Kyung Lim
Yonsei Medical Journal.2019; 60(8): 796. CrossRef
Effect of Institutional Case Volume on In-hospital Mortality After Living Donor Liver Transplantation: Analysis of 7073 Cases Between 2007 and 2016 in Korea
Seokha Yoo, Eun Jin Jang, Nam-Joon Yi, Ga Hee Kim, Dal Ho Kim, Hannah Lee, Chul-Woo Jung, Ho Geol Ryu
Transplantation.2019; 103(5): 952. CrossRef
Increased risk of benign paroxysmal positional vertigo in osteoporosis: a nationwide population-based cohort study
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Scientific Reports.2019;[Epub] CrossRef
Incremental economic burden associated with exudative age-related macular degeneration: a population-based study
Siin Kim, Sang Jun Park, Seong Jun Byun, Kyu Hyung Park, Hae Sun Suh
BMC Health Services Research.2019;[Epub] CrossRef
Patients with Inflammatory Bowel Disease Are at an Increased Risk of Parkinson’s Disease: A South Korean Nationwide Population-Based Study
Seona Park, Jihye Kim, Jaeyoung Chun, Kyungdo Han, Hosim Soh, Eun Ae Kang, Hyun Jung Lee, Jong Pil Im, Joo Sung Kim
Journal of Clinical Medicine.2019; 8(8): 1191. CrossRef
Effect of hypertension duration and blood pressure level on ischaemic stroke risk in atrial fibrillation: nationwide data covering the entire Korean population
Tae-Hoon Kim, Pil-Sung Yang, Hee Tae Yu, Eunsun Jang, Hyejung Shin, Ha Yan Kim, Jae-Sun Uhm, Jong-Youn Kim, Jung-Hoon Sung, Hui-Nam Pak, Moon-Hyoung Lee, Boyoung Joung, Gregory Y H Lip
European Heart Journal.2019; 40(10): 809. CrossRef
Perioperative red blood cell transfusion and mortality following heart transplantation: A retrospective nationwide population‐based study between 2007 and 2016 in Korea
Karam Nam, Eun Jin Jang, Ga Hee Kim, Hyung Been Yhim, Hannah Lee, Dal Ho Kim, Ho Geol Ryu
Journal of Cardiac Surgery.2019; 34(10): 927. CrossRef
The Effect of Health-Related Behaviors on Disease Progression and Mortality in Early Stages of Chronic Kidney Disease: A Korean Nationwide Population-Based Study
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Journal of Clinical Medicine.2019; 8(8): 1100. CrossRef
Association of body mass index with bladder cancer risk in men depends on abdominal obesity
Jin Bong Choi, Jung Ho Kim, Sung-Hoo Hong, Kyung-Do Han, U-Syn Ha
World Journal of Urology.2019; 37(11): 2393. CrossRef
Time‐ and Dose‐Dependent Association of Statin Use With Risk of Clinically Relevant New‐Onset Diabetes Mellitus in Primary Prevention: A Nationwide Observational Cohort Study
Min Jung Ko, Ae Jeong Jo, Yun Jung Kim, Shin Hee Kang, Songhee Cho, Sang‐Ho Jo, Cheol‐Young Park, Sung‐Cheol Yun, Woo Je Lee, Duk‐Woo Park
Journal of the American Heart Association.2019;[Epub] CrossRef
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Diabetes & Metabolism.2019; 45(1): 19. CrossRef
Risk of Incident Dementia According to Metabolic Health and Obesity Status in Late Life: A Population-Based Cohort Study
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The Journal of Clinical Endocrinology & Metabolism.2019; 104(7): 2942. CrossRef
Increased Risk of Osteoporotic Fracture in Postgastrectomy Gastric Cancer Survivors Compared With Matched Controls: A Nationwide Cohort Study in Korea
Dong Wook Shin, Beomseok Suh, Hyunsun Lim, Yun-Suhk Suh, Yoon Jin Choi, Su-Min Jeong, Jae Moon Yun, Sun Ok Song, Youngmin Park
American Journal of Gastroenterology.2019; 114(11): 1735. CrossRef
Metabolic syndrome is associated with an increased risk of psoriasis: A nationwide population-based study
Ha-Na Kim, Kyungdo Han, Yong-Gyu Park, Ji Hyun Lee
Metabolism.2019; 99: 19. CrossRef
Association of Exposure to Diagnostic Low-Dose Ionizing Radiation With Risk of Cancer Among Youths in South Korea
Jae-Young Hong, Kyungdo Han, Jin-Hyung Jung, Jung Sun Kim
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Long‐term clinical outcomes in patients with autoimmune hepatitis according to treatment response in Asian country
Jonggi Choi, Gwang Hyeon Choi, Danbi Lee, Ju Hyun Shim, Young‐Suk Lim, Han Chu Lee, Young‐Hwa Chung, Yung‐Sang Lee, Kang Mo Kim
Liver International.2019; 39(5): 985. CrossRef
Effectiveness and Safety of Direct Oral Anticoagulant for Secondary Prevention in Asians with Atrial Fibrillation
Jiesuck Park, So-Ryoung Lee, Eue-Keun Choi, Soonil Kwon, Jin-Hyung Jung, Kyung-Do Han, Myung-Jin Cha, Sang-Bae Ko, Seil Oh, Gregory Y. H. Lip
Journal of Clinical Medicine.2019; 8(12): 2228. CrossRef
Optimal Rivaroxaban Dose in Asian Patients With Atrial Fibrillation and Normal or Mildly Impaired Renal Function
So-Ryoung Lee, Eue-Keun Choi, Kyung-Do Han, Jin-Hyung Jung, Seil Oh, Gregory Y.H. Lip
Stroke.2019; 50(5): 1140. CrossRef
Tobacco Smoking and Alcohol Consumption Are Related to Benign Parotid Tumor: A Nested Case-Control Study Using a National Health Screening Cohort
So Young Kim, Chanyang Min, Dong Jun Oh, Hyo Geun Choi
Clinical and Experimental Otorhinolaryngology.2019; 12(4): 412. CrossRef
Increased Risk of Diabetes in Inflammatory Bowel Disease Patients: A Nationwide Population-Based Study in Korea
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Journal of Clinical Medicine.2019; 8(3): 343. CrossRef
Changes in the Diagnostic Efficiency of Thyroid Fine-Needle Aspiration Biopsy during the Era of Increased Thyroid Cancer Screening in Korea
Young Ki Lee, Kyeong Hye Park, Young Duk Song, Taemi Youk, Joo Young Nam, Sun Ok Song, Dong Yeob Shin, Eun Jig Lee
Cancer Research and Treatment.2019; 51(4): 1430. CrossRef
Safety and Effectiveness of Contemporary P2Y 12 Inhibitors in an East Asian Population With Acute Coronary Syndrome: A Nationwide Population‐Based Cohort Study
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Direct Oral Anticoagulants in Patients With Nonvalvular Atrial Fibrillation and Low Body Weight
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Journal of the American College of Cardiology.2019; 73(8): 919. CrossRef
Trends in varicella and herpes zoster epidemiology before and after the implementation of universal one-dose varicella vaccination over one decade in South Korea, 2003–2015
Jae-Ki Choi, Sun Hee Park, Sanghyun Park, Su-Mi Choi, Si-Hyun Kim, Dong-Gun Lee, Jin-Hong Yoo, Jung-Hyun Choi, Jin Han Kang
Human Vaccines & Immunotherapeutics.2019; 15(11): 2554. CrossRef
Obesity Fact Sheet in Korea, 2018: Data Focusing on Waist Circumference and Obesity-Related Comorbidities
Ga Eun Nam, Yang-Hyun Kim, Kyungdo Han, Jin-Hyung Jung, Yong Gyu Park, Kwan-Woo Lee, Eun-Jung Rhee, Jang Won Son, Seong-Su Lee, Hyuk-Sang Kwon, Won-Young Lee, Soon Jib Yoo
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Long-Term Impact of Newly Diagnosed Atrial Fibrillation During Critical Care
Kyu Kim, Pil-Sung Yang, Eunsun Jang, Hee Tae Yu, Tae-Hoon Kim, Jae-Sun Uhm, Jong-Youn Kim, Jung-Hoon Sung, Hui-Nam Pak, Moon-Hyoung Lee, Gregory Y.H. Lip, Boyoung Joung
Chest.2019; 156(3): 518. CrossRef
Correlation of Androgen Deprivation Therapy with Cognitive Dysfunction in Patients with Prostate Cancer: A Nationwide Population-Based Study Using the National Health Insurance Service Database
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Cancer Research and Treatment.2019; 51(2): 593. CrossRef
Non-Vitamin K Antagonist Oral Anticoagulants in Patients with Atrial Fibrillation and Valvular Heart Disease
Inki Moon, So-Ryoung Lee, Eue-Keun Choi, Euijae Lee, Jin-Hyung Jung, Kyung-Do Han, Myung-Jin Cha, Seil Oh, Gregory Y.H. Lip
Journal of Clinical Medicine.2019; 8(10): 1624. CrossRef
Relation between Baseline Height and New Diabetes Development: A Nationwide Population-Based Study
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The Risk of Myocardial Infarction and Ischemic Stroke According to Waist Circumference in 21,749,261 Korean Adults: A Nationwide Population-Based Study
Jung-Hwan Cho, Eun-Jung Rhee, Se-Eun Park, Hyemi Kwon, Jin-Hyung Jung, Kyung-Do Han, Yong-Gyu Park, Hye Soon Park, Yang-Hyun Kim, Soon-Jib Yoo, Won-Young Lee
Diabetes & Metabolism Journal.2019; 43(2): 206. CrossRef
The risk of end-stage renal disease in systemic lupus erythematosus
Hong Sang Choi, Kyung-Do Han, Jin-Hyung Jung, Chang Seong Kim, Eun Hui Bae, Seong Kwon Ma, Soo Wan Kim
Medicine.2019; 98(28): e16420. CrossRef
Antithrombotic Therapy in Patients With Atrial Fibrillation After Percutaneous Coronary Intervention During 2-Year Follow-Up, from a Nationwide Population Study
Jiesuck Park, Eue-Keun Choi, Kyung-Do Han, You-Jung Choi, So-Ryoung Lee, Myung-Jin Cha, Jeehoon Kang, Kyung Woo Park, Seil Oh, Gregory Y.H. Lip
The American Journal of Cardiology.2019; 123(12): 1921. CrossRef
Outcomes After Use of Standard- and Low-Dose Non–Vitamin K Oral Anticoagulants in Asian Patients With Atrial Fibrillation
Min Soo Cho, Ji Eun Yun, Ji Jeong Park, Yun Jung Kim, Jessie Lee, Hyungmin Kim, Duk-Woo Park, Gi-Byoung Nam
Stroke.2019; 50(1): 110. CrossRef
Association between Atrial Fibrillation, Myocardial Infarction, Heart Failure and Mortality in Patients with Nontuberculous Mycobacterial Infection: a nationwide population-based study
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Scientific Reports.2019;[Epub] CrossRef
National practice patterns and direct medical costs for prostate cancer in Korea across a 10 year period: a nationwide population-based study using a national health insurance database
Ho Won Kang, Seok-Joong Yun, Jae Il Chung, Hoon Choi, Jae Heon Kim, Ho Song Yu, Yun-Sok Ha, In-Chang Cho, Hyung Joon Kim, Hyun Chul Chung, Jun Sung Koh, Wun-Jae Kim, Jong-Hyock Park, Ji Youl Lee, So-Young Kim
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Karam Nam, Eun Jin Jang, Ga Hee Kim, Hannah Lee, Dal Ho Kim, Ho Geol Ryu
International Heart Journal.2019; 60(3): 695. CrossRef
Weight change is significantly associated with risk of thyroid cancer: A nationwide population-based cohort study
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Scientific Reports.2019;[Epub] CrossRef
Venous thromboembolism in relapsed or refractory multiple myeloma patients treated with lenalidomide plus dexamethasone
Junghoon Shin, Je-Jung Lee, Kihyun Kim, Chang-Ki Min, Jeong-Ok Lee, Cheolwon Suh, Jin Seok Kim, Yoo Jin Lee, Sung-Soo Yoon, Jae-Cheol Jo, Ho Sup Lee, Soo-Mee Bang
International Journal of Hematology.2019; 109(1): 79. CrossRef
Actinic keratosis and diabetes complications: A nationwide population-based study in South Korea (2009–2015)
YoungBok Lee, JiHyun Lee, JinYoung Choi, DongSoo Yu, KyungDo Han, Yong-Gyu Park
Diabetes & Metabolism.2019; 45(1): 32. CrossRef
Ankylosing spondylitis: A novel risk factor for atrial fibrillation — A nationwide population-based study
Inki Moon, Eue-Keun Choi, Jin-Hyung Jung, Kyung-Do Han, You-Jung Choi, Jiesuck Park, Jun Hwan Cho, Euijae Lee, Wonseok Choe, So-Ryoung Lee, Myung-Jin Cha, Woo-Hyun Lim, Seil Oh
International Journal of Cardiology.2019; 275: 77. CrossRef
Cancer risk among young men with weight gain after smoking cessation: A population-based cohort study
Kyuwoong Kim, Seulggie Choi, Gyeongsil Lee, Su-Min Jeong, Sung Min Kim, Joung Sik Son, Jae-Moon Yun, Yeon-Yong Kim, Seong Yong Park, Sang Min Park
Cancer Epidemiology.2019; 60: 86. CrossRef
Effect of drug compliance on health care costs in newly-diagnosed dementia: Analysis of nationwide population-based data
Seung-Taek Oh, Kyu-Tae Han, Won-Jung Choi, Jaesub Park
Journal of Psychiatric Research.2019; 118: 31. CrossRef
Colorectal Cancer Risks According to Sex Differences in Patients With Type II Diabetes Mellitus: A Korean Nationwide Population-Based Cohort Study
Ji Min Lee, Kang-Moon Lee, Dae Bum Kim, Seung-Hyun Ko, Yong Gyu Park
Clinical and Translational Gastroenterology.2019; 10(10): e00090. CrossRef
Body Mass Index Variability and Long-term Risk of New-Onset Atrial Fibrillation in the General Population: A Korean Nationwide Cohort Study
Yeong-Min Lim, Pil-Sung Yang, Eunsun Jang, Hee Tae Yu, Tae-Hoon Kim, Jae-Sun Uhm, Jong-Youn Kim, Hui-Nam Pak, Moon-Hyoung Lee, Boyoung Joung, Gregory Y.H. Lip
Mayo Clinic Proceedings.2019; 94(2): 225. CrossRef
Childbirth in young Korean women with previously treated breast cancer: The SMARTSHIP study
Hak Min Lee, Bo Wook Kim, Seho Park, Sungmin Park, Jeon Eon Lee, Young Jin Choi, Sung Yong Kim, Sang Uk Woo, Hyun Jo Youn, Ilkyun Lee
Breast Cancer Research and Treatment.2019; 176(2): 419. CrossRef
Obstructive sleep apnea as a risk factor for incident end stage renal disease: a nationwide population-based cohort study from Korea
Hong Sang Choi, Ha Yeon Kim, Kyung-Do Han, Jin-Hyung Jung, Chang Seong Kim, Eun Hui Bae, Seong Kwon Ma, Soo Wan Kim
Clinical and Experimental Nephrology.2019; 23(12): 1391. CrossRef
Severe hypoglycemia and the risk of cardiovascular disease and mortality in type 2 diabetes: a nationwide population-based cohort study
Jae-Seung Yun, Yong-Moon Park, Kyungdo Han, Seon-Ah Cha, Yu-Bae Ahn, Seung-Hyun Ko
Cardiovascular Diabetology.2019;[Epub] CrossRef
Severity of dental caries and risk of coronary heart disease in middle-aged men and women: a population-based cohort study of Korean adults, 2002–2013
Kyuwoong Kim, Seulggie Choi, Jooyoung Chang, Sung Min Kim, Seon Jip Kim, Ryan Jin-Young Kim, Hyun-Jae Cho, Sang Min Park
Scientific Reports.2019;[Epub] CrossRef
Risk of Anxiety and Depression in Patients with Inflammatory Bowel Disease: A Nationwide, Population-Based Study
Kookhwan Choi, Jaeyoung Chun, Kyungdo Han, Seona Park, Hosim Soh, Jihye Kim, Jooyoung Lee, Hyun Lee, Jong Im, Joo Kim
Journal of Clinical Medicine.2019; 8(5): 654. CrossRef
The Effects after Implementing a Drug Utilization Review System on Contraindicated Drug use: A Systematic Review
Heeyoung Lee, Hyea Suk Choi, Eunhee Ji
Korean Journal of Clinical Pharmacy.2019; 29(1): 9. CrossRef
Nationwide Trends in Pancreatitis and Pancreatic Cancer Risk Among Patients With Newly Diagnosed Type 2 Diabetes Receiving Dipeptidyl Peptidase 4 Inhibitors
Minyoung Lee, Jiyu Sun, Minkyung Han, Yongin Cho, Ji-Yeon Lee, Chung Mo Nam, Eun Seok Kang
Diabetes Care.2019; 42(11): 2057. CrossRef
Dose–response relationship between cigarette smoking and risk of ulcerative colitis: a nationwide population-based study
Seona Park, Jaeyoung Chun, Kyung-Do Han, Hosim Soh, Eun Ae Kang, Hyun Jung Lee, Jong Pil Im, Joo Sung Kim
Journal of Gastroenterology.2019; 54(10): 881. CrossRef
Is androgen deprivation therapy associated with cerebral infarction in patients with prostate cancer? A Korean nationwide population‐based propensity score matching study
Bum Sik Tae, Byeong Jo Jeon, Hoon Choi, Jae Hyun Bae, Jae Young Park
Cancer Medicine.2019; 8(9): 4475. CrossRef
Adult lung transplantation case-volume and in-hospital and long-term mortality in Korea
Susie Yoon, Eun Jin Jang, Ga Hee Kim, Dal Ho Kim, Tae-Yoon Lim, Hannah Lee, Ho Geol Ryu
Journal of Cardiothoracic Surgery.2019;[Epub] CrossRef
Systemic lupus erythematosus is a risk factor for cancer: a nationwide population-based study in Korea
E.H. Bae, S.Y. Lim, K.-D. Han, J.-Hy. Jung, H.S. Choi, C.S. Kim, S.K. Ma, SW Kim
Lupus.2019; 28(3): 317. CrossRef
Association Between Drug Exposure and Occurrence of Parkinsonism in Korea: A Population-Based Case-Control Study
Siin Kim, Sang-Myung Cheon, Hae Sun Suh
Annals of Pharmacotherapy.2019; 53(11): 1102. CrossRef
Validation of diagnostic codes of major clinical outcomes in a National Health Insurance database
Jiesuck Park, Soonil Kwon, Eue-Keun Choi, You-jung Choi, Euijae Lee, Wonseok Choe, So-Ryoung Lee, Myung-Jin Cha, Woo-Hyun Lim, Seil Oh
International Journal of Arrhythmia.2019;[Epub] CrossRef
HDL-Cholesterol, Its Variability, and the Risk of Diabetes: A Nationwide Population-Based Study
Seung-Hwan Lee, Hun-Sung Kim, Yong-Moon Park, Hyuk-Sang Kwon, Kun-Ho Yoon, Kyungdo Han, Mee Kyoung Kim
The Journal of Clinical Endocrinology & Metabolism.2019; 104(11): 5633. CrossRef
Prognostic influence of Korean public medical insurance system on breast cancer patients
Ki-Tae Hwang, Young Wook Ju, Young A Kim, Jongjin Kim, Sohee Oh, Jiwoong Jung, Young Jun Chai, In Sil Choi, So Won Oh
Annals of Surgical Treatment and Research.2019; 96(2): 58. CrossRef
Effect of Case Volume on Mortality After Pediatric Liver Transplantation in Korea
Hannah Lee, Eun Jin Jang, Ga Hee Kim, Nam Joon Yi, Dal Ho Kim, Seokha Yoo, Hyung Sang Row, Chul-Woo Jung, Seung-Young Oh, Ho Geol Ryu
Transplantation.2019; 103(8): 1649. CrossRef
Prescription Patterns and Burden of Pediatric Asthma in Korea
In Suk Sol, Yoon Hee Kim, Soo Yeon Kim, Sun Ha Choi, Jong Deok Kim, Bo Ok Kim, Ji Eun Moon, Kyung Won Kim, Myung Hyun Sohn
Allergy, Asthma & Immunology Research.2019; 11(2): 280. CrossRef
Increased risk of coronary heart disease and stroke in lung cancer survivors: A Korean nationwide study of 20,458 patients
Dong Woog Yoon, Dong Wook Shin, Jong Ho Cho, Jeong Hoon Yang, Su-Min Jeong, Kyungdo Han, Sang Hyun Park
Lung Cancer.2019; 136: 115. CrossRef
Waist Circumference and All-Cause Mortality Independent of Body Mass Index in Korean Population from the National Health Insurance Health Checkup 2009–2015
Yang-Hyun Kim, Seon Mee Kim, Kyung-Do Han, Jin-Hyung Jung, Seong-Su Lee, Sang Woo Oh, Hye Soon Park, Eun-Jung Rhee, Won-Young Lee, Soon Jib Yoo
Journal of Clinical Medicine.2019; 8(1): 72. CrossRef
Temporal trends in prevalence and antithrombotic treatment among Asians with atrial fibrillation undergoing percutaneous coronary intervention: A nationwide Korean population-based study
Jiesuck Park, Eue-Keun Choi, Kyung-Do Han, You-jung Choi, Euijae Lee, Wonseok Choe, So-Ryoung Lee, Myung-Jin Cha, Woo-Hyun Lim, Jeehoon Kang, Kyung Woo Park, Seil Oh, Gregory Y. H. Lip, Chiara Lazzeri
PLOS ONE.2019; 14(1): e0209593. CrossRef
Factors influencing the incidence and treatment of intracranial aneurysm and subarachnoid hemorrhage: time trends and socioeconomic disparities under an universal healthcare system
Won Kyung Lee, Chang Wan Oh, Heeyoung Lee, Kun Sei Lee, Hyeonseon Park
Journal of NeuroInterventional Surgery.2019; 11(2): 159. CrossRef
Increasing trends in hospital care burden of atrial fibrillation in Korea, 2006 through 2015
Daehoon Kim, Pil-Sung Yang, Eunsun Jang, Hee Tae Yu, Tae-Hoon Kim, Jae-Sun Uhm, Jong Youn Kim, Hui-Nam Pak, Moon-Hyoung Lee, Boyoung Joung, Gregory Y H Lip
Heart.2018; 104(24): 2010. CrossRef
Appropriate Amount of Regular Exercise Is Associated with a Reduced Mortality Risk
DA YOUNG LEE, EUN-JUNG RHEE, JUNG HWAN CHO, HYEMI KWON, SE EUN PARK, YANG-HYUN KIM, KYUNGDO HAN, YONG-KYU PARK, SOON JIB YOO, WON-YOUNG LEE
Medicine & Science in Sports & Exercise.2018; 50(12): 2451. CrossRef
The effect of continuity of care on the incidence of end-stage renal disease in patients with newly detected type 2 diabetic nephropathy: a retrospective cohort study
Yun Jung Jang, Yoon Soo Choy, Chung Mo Nam, Ki Tae Moon, Eun-Cheol Park
BMC Nephrology.2018;[Epub] CrossRef
Increased end-stage renal disease risk in patients with inflammatory bowel disease: A nationwide population-based study
Seona Park, Jaeyoung Chun, Kyung-Do Han, Hosim Soh, Kookhwan Choi, Ji Hye Kim, Jooyoung Lee, Changhyun Lee, Jong Pil Im, Joo Sung Kim
World Journal of Gastroenterology.2018; 24(42): 4798. CrossRef
Cardiovascular disease risk differences between bus company employees and general workers according to the Korean National Health Insurance Data
Ji-Hoo Yook, Dong-Wook Lee, Min-Seok Kim, Yun-Chul Hong
Annals of Occupational and Environmental Medicine.2018;[Epub] CrossRef
Impact of Renal Function on Outcomes With Edoxaban in Real-World Patients With Atrial Fibrillation
Hee Tae Yu, Pil-Sung Yang, Tae-Hoon Kim, Eunsun Jang, Daehoon Kim, Jae-Sun Uhm, Jong-Youn Kim, Hui-Nam Pak, Moon-Hyoung Lee, Gregory Y.H. Lip, Boyoung Joung
Stroke.2018; 49(10): 2421. CrossRef
Association between adult height, myocardial infarction, heart failure, stroke and death: a Korean nationwide population-based study
Chan Soon Park, Eue-Keun Choi, Kyung-Do Han, Hyun Jung Lee, Tae-Min Rhee, So-Ryoung Lee, Myung-Jin Cha, Woo-Hyun Lim, Si-Hyuck Kang, Seil Oh
International Journal of Epidemiology.2018; 47(1): 289. CrossRef
Dietary Fat Intake and Risk of Colorectal Cancer: A Systematic Review and Meta-Analysis of Prospective Studies
Minkyeong Kim, Kyong Park
Nutrients.2018; 10(12): 1963. CrossRef
Association Between Changes in Hemoglobin Concentration and Cardiovascular Risks and All‐Cause Mortality Among Young Women
Gyeongsil Lee, Seulggie Choi, Kyuwoong Kim, Jae‐Moon Yun, Joung Sik Son, Su‐Min Jeong, Sung Min Kim, Yeon‐Yong Kim, Seong Yong Park, Youngil Koh, Seung‐sik Hwang, Sang Min Park
Journal of the American Heart Association.2018;[Epub] CrossRef
The economic burden of rotavirus infection in South Korea from 2009 to 2012
Kyung Suk Lee, Ye-Rin Lee, So-Youn Park, In-Hwan Oh, Donald R. Olson
PLOS ONE.2018; 13(3): e0194120. CrossRef
Incidence and death rate of pemphigus vulgaris and pemphigus foliaceus in Korea: A nationwide, population‐based study (2006–2015)
Young Bok Lee, Ji Hyun Lee, Soo Young Lee, Jin‐Wou Kim, Dong Soo Yu, Kyung Do Han, Yong Gyu Park
The Journal of Dermatology.2018; 45(12): 1396. CrossRef
Protective Effect of Metformin Against Thyroid Cancer Development: A Population-Based Study in Korea
Yoon Young Cho, Min Jin Kang, Soo Kyoung Kim, Jung Hwa Jung, Jong Ryeal Hahm, Tae Hyuk Kim, Joo Young Nam, Byung-Wan Lee, Yong-ho Lee, Jae Hoon Chung, Sun Ok Song, Sun Wook Kim
Thyroid.2018; 28(7): 864. CrossRef
Association of oral ciprofloxacin, levofloxacin, ofloxacin and moxifloxacin with the risk of serious ventricular arrhythmia: a nationwide cohort study in Korea
Yongil Cho, Hyun Soo Park
BMJ Open.2018; 8(9): e020974. CrossRef
The risk of alopecia areata and other related autoimmune diseases in patients with sleep disorders: a Korean population–based retrospective cohort study
Hyun-Min Seo, Tae Lim Kim, Joung Soo Kim
Sleep.2018;[Epub] CrossRef
Evaluation of relationships between onychomycosis and vascular diseases using sequential pattern mining
Chul Hwan Bang, Jae Woong Yoon, Hyun Ji Lee, Jun Young Lee, Young Min Park, Suk Jun Lee, Ji Hyun Lee
Scientific Reports.2018;[Epub] CrossRef
Age Threshold for Ischemic Stroke Risk in Atrial Fibrillation
Tae-Hoon Kim, Pil-Sung Yang, Hee Tae Yu, Eunsun Jang, Jae-Sun Uhm, Jong-Youn Kim, Hui-Nam Pak, Moon-Hyoung Lee, Boyoung Joung, Gregory Y.H. Lip
Stroke.2018; 49(8): 1872. CrossRef
Variations of Prevalence and Incidence of Atrial Fibrillation and Oral Anticoagulation Rate According to Different Analysis Approaches
Pil-Sung Yang, Soorack Ryu, Daehoon Kim, Eunsun Jang, Hee Tae Yu, Tae-Hoon Kim, Jinseub Hwang, Boyoung Joung, Gregory Y. H. Lip
Scientific Reports.2018;[Epub] CrossRef
Reciprocal relationship between herpes zoster and cardiovascular diseases: A nationwide population‐based case–control study in Korea
Hyun‐Min Seo, Myung‐Jin Cha, Ju Hee Han, Kyungdo Han, Sang Hyun Park, Chul Hwan Bang, Ji Hyun Lee, Jun Young Lee, Eue‐Keun Choi, Young Min Park
The Journal of Dermatology.2018; 45(11): 1312. CrossRef
Hypertension and risk of psoriasis incidence: An 11-year nationwide population-based cohort study
Ha-Na Kim, Kyungdo Han, Sang-Wook Song, Ji Hyun Lee, Valerio De Vita
PLOS ONE.2018; 13(8): e0202854. CrossRef
Association between abdominal obesity and increased risk for the development of hypertension regardless of physical activity: A nationwide population‐based study
Eun‐Jung Rhee, Jung‐Hwan Cho, Hyemi Kwon, Se‐Eun Park, Jin‐Hyung Jung, Kyung‐Do Han, Yong‐Gyu Park, Hye Soon Park, Yang‐Hyun Kim, Soon‐Jib Yoo, Won‐Young Lee
The Journal of Clinical Hypertension.2018; 20(10): 1417. CrossRef
Prevalence of extraintestinal manifestations in Korean inflammatory bowel disease patients
Bo Ram Yang, Nam-Kyong Choi, Mi-Sook Kim, Jaeyoung Chun, Sang Hyun Joo, Hyesung Kim, Joongyub Lee, Gang Liu
PLOS ONE.2018; 13(7): e0200363. CrossRef
Need for Systematic Efforts to Modify Health-Related Behaviors After Acute Myocardial Infarction in Korea
Seungwoo Cha, Jin Joo Park, Sunyoung Kim, Hong-Yup Ahn, Kyungdo Han, Yookyung Lee, Won-Seok Kim, Nam-Jong Paik
Circulation Journal.2018; 82(10): 2523. CrossRef
Association between diabetes and asthma
Ji Yeon Baek, Seung Eun Lee, Kyungdo Han, Eun Hee Koh
Annals of Allergy, Asthma & Immunology.2018; 121(6): 699. CrossRef
Association between Height and Actinic Keratosis: A Nationwide Population-based Study in South Korea
Young Bok Lee, Ji Hyun Lee, Min Ji Kang, Jin-Wou Kim, Dong Soo Yu, Kyung Do Han, Yong Gyu Park
Scientific Reports.2018;[Epub] CrossRef
Effect of Institutional Case Volume on In-Hospital Mortality After Deceased Donor Liver Transplantation: A Nationwide Retrospective Cohort Study in Korea
S. Yoo, E.J. Jang, G.H. Kim, D.H. Kim, S.M. Kwon, H. Lee, C.-W. Jung, H.G. Ryu
Transplantation Proceedings.2018; 50(10): 3644. CrossRef
Past and Current Status of Adult Type 2 Diabetes Mellitus Management in Korea: A National Health Insurance Service Database Analysis
Seung-Hyun Ko, Kyungdo Han, Yong-ho Lee, Junghyun Noh, Cheol-Young Park, Dae-Jung Kim, Chang Hee Jung, Ki-Up Lee, Kyung-Soo Ko
Diabetes & Metabolism Journal.2018; 42(2): 93. CrossRef
Difference in prostate cancer incidence around sixty years: effects of age and metabolic diseases
Jin Bong Choi, Jung Ho Kim, Sung‐Hoo Hong, Kyung‐Do Han, U‐Syn Ha
Cancer Medicine.2018; 7(6): 2736. CrossRef
A nationwide population-based study of common bile duct stone recurrence after endoscopic stone removal in Korea
Byung Kyu Park, Jeong Hun Seo, Han Ho Jeon, Jong Won Choi, Sun Young Won, Yong Suk Cho, Chun Kyon Lee, Haeyong Park, Dong Wook Kim
Journal of Gastroenterology.2018; 53(5): 670. CrossRef
Estimating the impact of body mass index on bladder cancer risk: Stratification by smoking status
Jin Bong Choi, Eun Joo Lee, Kyung-Do Han, Sung-Hoo Hong, U-Syn Ha
Scientific Reports.2018;[Epub] CrossRef
Prevalence of Obesity and Incidence of Obesity-Related Comorbidities in Koreans Based on National Health Insurance Service Health Checkup Data 2006–2015
Mi Hae Seo, Yang-Hyun Kim, Kyungdo Han, Jin-Hyung Jung, Yong-Gyu Park, Seong-Su Lee, Hyuk-Sang Kwon, Won-Young Lee, Soon Jib Yoo
Journal of Obesity & Metabolic Syndrome.2018; 27(1): 46. CrossRef
Association of Hemoglobin Concentration and Its Change With Cardiovascular and All‐Cause Mortality
Gyeongsil Lee, Seulggie Choi, Kyuwoong Kim, Jae‐Moon Yun, Joung Sik Son, Su‐Min Jeong, Sung Min Kim, Sang Min Park
Journal of the American Heart Association.2018;[Epub] CrossRef
Impact of acupuncture treatment on the lumbar surgery rate for low back pain in Korea: A nationwide matched retrospective cohort study
Wonil Koh, Kyungwon Kang, Yoon Jae Lee, Me-riong Kim, Joon-Shik Shin, Jinho Lee, Jun-Hwan Lee, Kyung-Min Shin, In-Hyuk Ha, Qinhong Zhang
PLOS ONE.2018; 13(6): e0199042. CrossRef
The influence of diabetes and antidiabetic medications on the risk of pancreatic cancer: a nationwide population-based study in Korea
Da Young Lee, Ji Hee Yu, Sanghyun Park, Kyungdo Han, Nam Hoon Kim, Hye Jin Yoo, Kyung Mook Choi, Sei Hyun Baik, Nan Hee Kim, Ji A. Seo
Scientific Reports.2018;[Epub] CrossRef
Validation of Administrative Big Database for Colorectal Cancer Searched by International Classification of Disease 10th Codes in Korean: A Retrospective Big-cohort Study
Young-Jae Hwang, Nayoung Kim, Chang Yong Yun, Hyuk Yoon, Cheol Min Shin, Young Soo Park, Il Tae Son, Heung-Kwon Oh, Duck-Woo Kim, Sung-Bum Kang, Hye Seung Lee, Seon Mee Park, Dong Ho Lee
Journal of Cancer Prevention.2018; 23(4): 183. CrossRef
J-Shaped Association Between Postoperative Levothyroxine Dosage and Fracture Risk in Thyroid Cancer Patients: A Retrospective Cohort Study
Dong Wook Shin, Beomseok Suh, Hyunsun Lim, Jae Moon Yun, Sun Ok Song, Youngmin Park
Journal of Bone and Mineral Research.2018; 33(6): 1037. CrossRef
Liver cirrhosis and cancer: comparison of mortality
Wankyo Chung, Changik Jo, Woo Jin Chung, Dong Joon Kim
Hepatology International.2018; 12(3): 269. CrossRef
Risk of ischemic stroke in metabolically healthy obesity: A nationwide population-based study
Hyun-Jung Lee, Eue-Keun Choi, Seung-Hwan Lee, Yong-Jin Kim, Kyung-Do Han, Seil Oh, Manlio Vinciguerra
PLOS ONE.2018; 13(3): e0195210. CrossRef
Incidence, prevalence, and mortality of Adamantiades‐Behçet's disease in Korea: a nationwide, population‐based study (2006–2015)
Y.B. Lee, S.Y. Lee, J.Y. Choi, J.H. Lee, H.S. Chae, J.W. Kim, K.D. Han, Y.G. Park, D.S. Yu
Journal of the European Academy of Dermatology and Venereology.2018; 32(6): 999. CrossRef
Temporal trends of antithrombotic therapy for stroke prevention in Korean patients with non-valvular atrial fibrillation in the era of non-vitamin K antagonist oral anticoagulants: A nationwide population-based study
So-Ryoung Lee, Eue-Keun Choi, Kyung-Do Han, Myung-Jin Cha, Seil Oh, Gregory Y. H. Lip, Thanh G Phan
PLOS ONE.2017; 12(12): e0189495. CrossRef
Persistent smoking after a cardiovascular event: A nationwide retrospective study in Korea
Yoo Kyoung Lim, Dong Wook Shin, Hyeon Suk Kim, Jae Moon Yun, Jung-Hyun Shin, Hyejin Lee, Hye Yeon Koo, Min Jung Kim, Jeong Yeon Yoon, Mi Hee Cho, Katriina Aalto-Setala
PLOS ONE.2017; 12(10): e0186872. CrossRef
Change in Weight and Body Mass Index Associated With All-Cause Mortality in Korea: A Nationwide Longitudinal Study
Yang-Hyun Kim, Seon Mee Kim, Kyung-do Han, Jang-Won Son, Seong-Su Lee, Sang Woo Oh, Won-Young Lee, Soon Jib Yoo
The Journal of Clinical Endocrinology & Metabolism.2017; 102(11): 4041. CrossRef
Secondary Primary Prostate Cancer after Colorectal Cancer: A Nationwide Population-based Cohort Study in Korea
Hyun Soo Kim, Yoon Jin Choi, Dong Woo Shin, Kyung-Do Han, Hyuk Yoon, Cheol Min Shin, Young Soo Park, Nayoung Kim, Dong Ho Lee
Journal of Cancer Prevention.2017; 22(4): 241. CrossRef
Increasing burden of liver cancer despite extensive use of antiviral agents in a hepatitis B virus‐endemic population
Jonggi Choi, Seungbong Han, Namkug Kim, Young‐Suk Lim
Hepatology.2017; 66(5): 1454. CrossRef
Data Analytic Process of a Nationwide Population-Based Study on Obesity Using the National Health Information Database Presented by the National Health Insurance Service 2006-2015
Yang-Hyun Kim, Kyungdo Han, Jang-Won Son, Seong-Su Lee, Sang Woo Oh, Hyuk-Sang Kwon, Soon-Ae Shin, Yeon-Yong Kim, Won-Young Lee, Soon Jib Yoo
Journal of Obesity & Metabolic Syndrome.2017; 26(1): 23. CrossRef
Trends in the incidence and prevalence of atrial fibrillation and estimated thromboembolic risk using the CHA2DS2-VASc score in the entire Korean population
So-Ryoung Lee, Eue-Keun Choi, Kyung-Do Han, Myung-Jin Cha, Seil Oh
International Journal of Cardiology.2017; 236: 226. CrossRef
Home Return After Surgery in Patients Aged over 85 Years is Associated with Preoperative Albumin Levels, the Type of Surgery, and APACHE II Score
Bora Lee, Sungwon Na, Miran Park, Sungyeon Ham, Jeongmin Kim
World Journal of Surgery.2017; 41(4): 919. CrossRef
Atrial fibrillation and the risk of myocardial infarction: a nation-wide propensity-matched study
Hye Young Lee, Pil-Sung Yang, Tae-Hoon Kim, Jae-Sun Uhm, Hui-Nam Pak, Moon-Hyoung Lee, Boyoung Joung
Scientific Reports.2017;[Epub] CrossRef
Regional variations in frequency of glycosylated hemoglobin (HbA1c) monitoring in Korea: A multilevel analysis of nationwide data
Kyoung-Hun Yoo, Dong-Wook Shin, Mi-Hee Cho, Sang-Hyuck Kim, Hyun-Jung Bahk, Shin-Hye Kim, Su-Min Jeong, Jae-Moon Yun, Jin-Ho Park, Heesun Kim, BeLong Cho
Diabetes Research and Clinical Practice.2017; 131: 61. CrossRef
Pediatric fluoroquinolone prescription in South Korea before and after a regulatory intervention: A nationwide study, 2007-2015
Seung Yeon Song, Joo Hee Shin, Su Yeong Hyeon, Donguk Kim, Won Ku Kang, Soo-Han Choi, Yae-Jean Kim, Eun Young Kim, Ravi Jhaveri
PLOS ONE.2017; 12(5): e0176420. CrossRef
Recent Shift of Body Mass Index Distribution in Korea: a Population-based Korea National Health Insurance Database, 2002–2013
Yeong Sook Yoon, Sang Woo Oh
Journal of Korean Medical Science.2017; 32(3): 434. CrossRef
Increased risk of thyroid diseases in patients with systemic lupus erythematosus: A nationwide population-based Study in Korea
Jae-Seung Yun, Jung Min Bae, Ki-Jo Kim, Yu Seok Jung, Gyong Moon Kim, Hyung-Rae Kim, Jun-Seok Lee, Seung-Hyun Ko, Seon-Ah Cha, Yu-Bae Ahn, Ludmila Prokunina-Olsson
PLOS ONE.2017; 12(6): e0179088. CrossRef
Trends in the pervasiveness of type 2 diabetes, impaired fasting glucose and co-morbidities during an 8-year-follow-up of nationwide Korean population
Junghyun Noh, Kyung-Do Han, Seung-Hyun Ko, Kyung Soo Ko, Cheol-Young Park
Scientific Reports.2017;[Epub] CrossRef
Impact of National Health Checkup Service on Hard Atherosclerotic Cardiovascular Disease Events and All-Cause Mortality in the General Population
Yongsung Suh, Chan Joo Lee, Deok-Kyu Cho, Yun-Hyeong Cho, Dong-Ho Shin, Chul-Min Ahn, Jung-Sun Kim, Byeong-Keuk Kim, Young-Guk Ko, Donghoon Choi, Yangsoo Jang, Myeong-Ki Hong
The American Journal of Cardiology.2017; 120(10): 1804. CrossRef
Data Analytic Process of a Nationwide Population-Based Study Using National Health Information Database Established by National Health Insurance Service
Yong-ho Lee, Kyungdo Han, Seung-Hyun Ko, Kyung Soo Ko, Ki-Up Lee
Diabetes & Metabolism Journal.2016; 40(1): 79. CrossRef
Trends in Diabetes Incidence in the Last Decade Based on Korean National Health Insurance Claims Data
Sun Ok Song, Yong-ho Lee, Dong Wook Kim, Young Duk Song, Joo Young Nam, Kyoung Hye Park, Dae Jung Kim, Seok Won Park, Hyun Chul Lee, Byung-Wan Lee
Endocrinology and Metabolism.2016; 31(2): 292. CrossRef
Obesity, metabolic health, and mortality in adults: a nationwide population-based study in Korea
Hae Kyung Yang, Kyungdo Han, Hyuk-Sang Kwon, Yong-Moon Park, Jae-Hyoung Cho, Kun-Ho Yoon, Moo-Il Kang, Bong-Yun Cha, Seung-Hwan Lee
Scientific Reports.2016;[Epub] CrossRef
Epidemiology of Type 1 Diabetes Mellitus in Korea through an Investigation of the National Registration Project of Type 1 Diabetes for the Reimbursement of Glucometer Strips with Additional Analyses Using Claims Data
Sun Ok Song, Young Duk Song, Joo Young Nam, Kyeong Hye Park, Ji-Hae Yoon, Kyung-Mi Son, Young Ko, Dong-Ha Lim
Diabetes & Metabolism Journal.2016; 40(1): 35. CrossRef
Central nervous system diseases of organic solvents exposed workers based on nationwide medical surveillance‐data in Korea
Young‐Sun Min, Yeon‐Soon Ahn
American Journal of Industrial Medicine.2016; 59(5): 392. CrossRef
Metabolic Risk Profile and Cancer in Korean Men and Women
Seulki Ko, Seok-Jun Yoon, Dongwoo Kim, A-Rim Kim, Eun-Jung Kim, Hye-Young Seo
Journal of Preventive Medicine and Public Health.2016; 49(3): 143. CrossRef
Trends of antidiabetic drug use in adult type 2 diabetes in Korea in 2002–2013
Seung-Hyun Ko, Dae-Jung Kim, Jong-Heon Park, Cheol-Young Park, Chang Hee Jung, Hyuk-Sang Kwon, Joong-Yeol Park, Kee-Ho Song, Kyungdo Han, Ki-Up Lee, Kyung-Soo Ko
Medicine.2016; 95(27): e4018. CrossRef
Hypoglycemia is associated with dementia in elderly patients with type 2 diabetes mellitus: An analysis based on the Korea National Diabetes Program Cohort
Sang Ouk Chin, Sang Youl Rhee, Suk Chon, Sei Hyun Baik, Yongsoo Park, Moon Suk Nam, Kwan Woo Lee, Ki Hong Chun, Jeong-taek Woo, Young Seol Kim
Diabetes Research and Clinical Practice.2016; 122: 54. CrossRef
How Can We Identify the Elimination of Infectious Diseases? Experience From an Active Measles Laboratory Surveillance System in the Republic of Korea
Tae Un Yang, Hae Ji Kang, Hye Eun Eom, Young-Joon Park, Ok Park, Su Jin Kim, Jeong-Gu Nam, Sung Soon Kim, Eun Kyeong Jeong
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A Novel Therapeutic Agent for Type 2 Diabetes Mellitus: SGLT2 Inhibitor: Chang Hee Jung, Jung Eun Jang, Joong-Yeol Park; Diabetes Metab J. 2014;38(4):261-273. Published online August 20, 2014; DOI: https://doi.org/10.4093/dmj.2014.38.4.261

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Type 2 diabetes mellitus (T2DM) is a complex endocrine and metabolic disorder, and a major public health problem that is rapidly increasing in prevalence. Although a wide range of pharmacotherapies for glycemic control is now available, management of T2DM remains complex and challenging. The kidneys contribute immensely to glucose homeostasis by reabsorbing glucose from the glomerular filtrate. Sodium-glucose cotransporter 2 (SGLT2) inhibitors, a new class of antidiabetic agents that inhibit glucose absorption from the kidney independent of insulin, offer a unique opportunity to improve the outcomes of patients with T2DM. In this review, we provide an overview of two globally-approved SGLT2 inhibitors, dapagliflozin and canagliflozin, and discuss their effects and safety. This information will help clinicians to decide whether these drugs will benefit their patients.

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Low Density Lipoprotein Cholesterol Target Goal Attainment Rate and Physician Perceptions about Target Goal Achievement in Korean Patients with Diabetes: Jenie Yoonoo Hwang, Chang Hee Jung, Woo Je Lee, Cheol Young Park, Sung Rae Kim, Kun-Ho Yoon, Moon Kyu Lee, Sung Woo Park, Joong-Yeol Park; Diabetes Metab J. 2011;35(6):628-636. Published online December 26, 2011; DOI: https://doi.org/10.4093/dmj.2011.35.6.628

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Background

This study aims to investigate the discrepancy between clinicians' perceptions and actual achievement rates of low density lipoprotein cholesterol (LDL-C) in Korean patients with diabetes according to updated American Diabetes Association (ADA)/American College of Cardiology Foundation (ACC) recommendations.

Methods

This is a multi-center, retrospective, non-interventional, observational study. Diabetic patients aged 18 years or older were eligible if they had been diagnosed with hypercholesterolemia or were receiving a lipid-lowering therapy between May 2010 and August 2010. The information was obtained by reviewing medical records and using a self-completed questionnaire to examine physician perceptions.

Results

A total of 2,591 subjects who satisfied the inclusion criteria were enrolled. Highest-risk and high-risk patients accounted for 61.9% and 38.1% of the patients, respectively. Although most (96.3%) underwent a statin monotherapy or a statin-based combination therapy, just 47.4% of patients attained the LDL-C target. However, the physicians' perceptions on target achievement rate (70.6%) were different from the actual results (47.4%). Many patients (65.3%) remained on the starting doses of statins, despite evidence of poor achievement of lipid goals.

Conclusion

Only less than half of patients with diabetes attained the LDL-C goal. The surveys showed that poor physician performance might be due to the lack of recognition on ADA/ACC consensus causing a low LDL-C target attainment rate. Therefore, changes in doctor perception are needed to attain target LDL-C level and reduce cardiovascular risk in Korean patients with diabetes.

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The Prevalence of Peripheral Arterial Disease in Korean Patients with Type 2 Diabetes Mellitus Attending a University Hospital: Ji Hee Yu, Jenie Yoonoo Hwang, Mi-Seon Shin, Chang Hee Jung, Eun Hee Kim, Sang Ah Lee, Eun Hee Koh, Woo Je Lee, Min-Seon Kim, Joong-Yeol Park, Ki-Up Lee; Diabetes Metab J. 2011;35(5):543-550. Published online October 31, 2011; DOI: https://doi.org/10.4093/dmj.2011.35.5.543

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Background

Peripheral arterial disease (PAD) is a common manifestation of systemic atherosclerosis and is associated with significant morbidity and mortality. Diabetes is known to increase the risk of PAD two- to four-fold. The prevalence of PAD in Korean diabetic patients has not been established. In this study, we investigated the prevalence of PAD in Korean patients with type 2 diabetes attending a large university hospital and analyzed the factors associated with PAD.

Methods

A total of 2,002 patients with type 2 diabetes who underwent ankle-brachial index (ABI) measurement in an outpatient clinic were enrolled. PAD was defined as an ABI ≤0.9. Clinical characteristics of 64 patients with PAD were compared with those of 192 age- and sex-matched control patients without PAD.

Results

Of the 2,002 type 2 diabetic patients, 64 (3.2%) were diagnosed as having PAD. PAD was associated with higher prevalences of retinopathy, nephropathy, neuropathy, cerebrovascular and coronary artery disease. Patients with PAD had higher systolic blood pressure and serum triglyceride level and reported higher pack-years of smoking. Multivariate analysis showed that the presence of micro- and macrovascular complications and high systolic blood pressure are factors independently associated with PAD.

Conclusion

The prevalence of PAD in diabetic patients was 3.2%, suggesting that the prevalence in Korean diabetic patients is lower than that of patients in Western countries.

Citations

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