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Keun Young Park  (Park KY) 1 Article
The Biochemical Markers of Coronary Heart Disease Correlates Better to Metabolic Syndrome Defined by WHO than by NCEP-ATP III or IDF in Korean Type 2 Diabetic Patients.
Dong Mee Lim, Keun Young Park, Gwan Pyo Koh
Korean Diabetes J. 2008;32(2):157-164.   Published online April 1, 2008
DOI: https://doi.org/10.4093/kdj.2008.32.2.157
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AbstractAbstract PDF
BACKGROUND
Metabolic syndrome (MetS) is constellation of cardiovascular risk factors. There are three typically used definitions of MetS proposed by WHO, IDF and NCEP-ATP III. We conducted this study to compare the associations of MetS by WHO, IDF and NCEP-ATP III definition to various metabolic markers of coronary heart diseases in Korean type 2 diabetes patients. METHODS: We enrolled 151 Korean type 2 diabetes patients in one hospital. Anthropometric and biochemical parameters, including high-sensitivity C-reactive protein (hsCRP), homocysteine, uric acid were measured. And then, we divided MetS group from non-MetS group according to three other definitions. RESULTS: Serum hsCRP level was higher in those with MetS group than non-MetS group by WHO definition (0.33 +/- 0.36 mg/dL vs 0.18 +/- 0.26 mg/dL, P < 0.001). But, there are no difference in MetS group and non-MetS group by IDF and NCEP-ATPIII definition. (By IDF, 0.28 +/- 0.31 mg/dL vs 0.25 +/- 0.34 mg/dL, P = 0.64; By NCEP-ATP III, 0.28 +/- 0.33 mg/dL vs 0.22 +/- 0.32 mg/dL, P = 0.41). Uric acid and homocysteine levels were higher in those with MetS by WHO definition (P < 0.05). Similarly, analyses according to IDF and NCEP ATP III definition showed no significant difference. CONCLUSION: In conclusion, WHO definition of MetS has a stronger relationship with the biochemical markers of coronary heart disease in Korean type 2 diabetes patients.

Citations

Citations to this article as recorded by  
  • Validation of Waist-to-Height Ratio for Predicting Metabolic Syndrome in Patients with Prediabetes (Korean J Obes 2015;24:36-43)
    Ji Min Kim, Bon Jeong Ku
    The Korean Journal of Obesity.2015; 24(3): 177.     CrossRef
  • Validation of Waist-to-Height Ratio for Predicting Metabolic Syndrome in Patients with Prediabetes
    Ji Min Kim, Min Kyung Back, Sang Hyeon Ju, Min Young Shin, Mi Joo Kim, Yeon-hee Park, Kwang-In Park, Kyong-Hye Joung, Hyun Jin Kim, Bon Jeong Ku
    The Korean Journal of Obesity.2015; 24(1): 36.     CrossRef
  • The Effects of U-Health Program on Metabolic Syndrome of Workers
    Hye-Sun Jung, Bokim Lee, Young-Hyun Kwon, Kyu-Ri Min, Su-Young Myung
    Korean Journal of Occupational Health Nursing.2014; 23(1): 47.     CrossRef
  • The Relationship between Factors of Metabolic Syndrome in Korean Adult Males and the Parents' Family History of Diabetes
    Hyung-Su Park, Jin-Gyu Jeong, Jin-Ho Yu
    The Journal of the Korea institute of electronic communication sciences.2013; 8(5): 779.     CrossRef
  • Use of Serum Homocysteine to Predict Cardiovascular Disease in Korean Men with or without Metabolic Syndrome
    Ji Yeon Kang, Ill Keun Park, Ji Young Lee, Sook Hee Sung, Youn Koun Chang, Yoo Kyoung Park, Tae In Choi
    Journal of Korean Medical Science.2012; 27(5): 500.     CrossRef

Diabetes Metab J : Diabetes & Metabolism Journal